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Search Results to Mitchell Mcgill

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One or more keywords matched the following items that are connected to Mcgill, Mitchell

Item TypeName
Concept Mitochondria, Liver
Concept Liver
Concept Liver Cirrhosis
Concept Liver Regeneration
Concept Liver Diseases
Concept End Stage Liver Disease
Concept Fatty Liver
Concept Liver Function Tests
Concept Liver Transplantation
Concept Liver Failure, Acute
Academic Article Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.
Academic Article A direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine and N-ethylmaleimide.
Academic Article Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.
Academic Article Inhibition of pannexin1 channels alleviates acetaminophen-induced hepatotoxicity.
Academic Article Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis.
Academic Article Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.
Academic Article Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis.
Academic Article Involvement of connexin43 in acetaminophen-induced liver injury.
Academic Article Caspase Inhibition Prevents Tumor Necrosis Factor-a-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro.
Academic Article Cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity.
Academic Article Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver.
Academic Article Pathophysiological relevance of neutrophils in acetaminophen hepatotoxicity.
Academic Article Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice.
Academic Article Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation.
Academic Article Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients.
Academic Article Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.
Academic Article The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury.
Academic Article Acetaminophen-induced Liver Injury: from Animal Models to Humans.
Academic Article Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.
Academic Article Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans.
Academic Article Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans.
Academic Article The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation.
Academic Article Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications.
Academic Article A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen.
Academic Article Hearing, reactive metabolite formation, and oxidative stress in cochleae after a single acute overdose of acetaminophen: an in vivo study.
Academic Article Caveats of using acetaminophen hepatotoxicity models for natural product testing.
Academic Article Critical review of resveratrol in xenobiotic-induced hepatotoxicity.
Academic Article Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity.
Academic Article Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways.
Academic Article Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase.
Academic Article MicroRNAs as Signaling Mediators and Biomarkers of Drug- and Chemical-Induced Liver Injury.
Academic Article Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity.
Academic Article Pathophysiological relevance of proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.
Academic Article Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis.
Academic Article HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity.
Academic Article Apoptosis or necrosis in acetaminophen-induced acute liver failure? New insights from mechanistic biomarkers*.
Academic Article Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity.
Academic Article Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice.
Academic Article Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome.
Academic Article Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury.
Academic Article Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity.
Academic Article RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity.
Academic Article Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice.
Academic Article Biomarkers of drug-induced liver injury: progress and utility in research, medicine, and regulation.
Academic Article The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.
Academic Article Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity.
Academic Article Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress.
Academic Article Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients.
Academic Article Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.
Academic Article Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells.
Academic Article Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products.
Academic Article Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.
Academic Article Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses.
Academic Article Argininosuccinate synthetase as a plasma biomarker of liver injury after acetaminophen overdose in rodents and humans.
Academic Article The Problem With Predictive Values: Are We Using the Right Metrics for Preclinical Prediction of Drug Hepatotoxicity?
Academic Article Protection against acetaminophen-induced liver injury by allopurinol is dependent on aldehyde oxidase-mediated liver preconditioning.
Academic Article Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products.
Academic Article Serum glutamate dehydrogenase--biomarker for liver cell death or mitochondrial dysfunction?
Academic Article The past and present of serum aminotransferases and the future of liver injury biomarkers.
Academic Article Connexin32: a mediator of acetaminophen-induced liver injury?
Academic Article The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3ß and Wnt/ß-catenin signaling.
Academic Article Propagation of Pericentral Necrosis During Acetaminophen-Induced Liver Injury: Evidence for Early Interhepatocyte Communication and Information Exchange.
Academic Article Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model.
Academic Article Decaffeinated Green Tea Extract Does Not Elicit Hepatotoxic Effects and Modulates the Gut Microbiome in Lean B6C3F1 Mice.
Academic Article Animal models of drug-induced liver injury.
Academic Article Expression of drug metabolizing enzymes and transporters in the cochlea: Implications for drug delivery and ototoxicity.
Academic Article Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration.
Academic Article Biomarkers of drug-induced liver injury.
Academic Article Mechanisms and biomarkers of liver regeneration after drug-induced liver injury.
Academic Article Effect of Bile Duct Ligation-induced Liver Dysfunction on Methamphetamine Pharmacokinetics and Locomotor Activity in Rats.
Academic Article Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children.
Academic Article Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations.
Academic Article Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms.
Academic Article Advances in biomarker development in acetaminophen toxicity.
Academic Article Effect of bile duct ligation-induced liver dysfunction on methamphetamine pharmacokinetics in male and female rats.
Academic Article Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis.
Academic Article Pre-treatment twice with liposomal clodronate protects against acetaminophen hepatotoxicity through a pre-conditioning effect.
Academic Article Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration.
Academic Article The development and hepatotoxicity of acetaminophen: reviewing over a century of progress.
Academic Article Biomarkers of mitotoxicity after acute liver injury: Further insights into the interpretation of glutamate dehydrogenase.
Academic Article Short-Term Safety of Repeated Acetaminophen Use in Patients With Compensated Cirrhosis.
Academic Article Redrawing the map to novel DILI biomarkers in circulation: Where are we, where should we go, and how can we get there?
Academic Article Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk.
Academic Article Radiation Effects on Methamphetamine Pharmacokinetics and Pharmacodynamics in Rats.
Academic Article Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways.
Academic Article Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients.

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