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Search Results to Brendan Frett

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One or more keywords matched the following items that are connected to Frett, Brendan

Item TypeName
Concept Proto-Oncogene Proteins
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogenes
Concept Proto-Oncogene Proteins c-kit
Concept Proto-Oncogene Proteins c-ret
Academic Article Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.
Academic Article Targeting the K-Ras/PDEd protein-protein interaction: the solution for Ras-driven cancers or just another therapeutic mirage?
Academic Article Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology.
Academic Article Identification of two novel RET kinase inhibitors through MCR-based drug discovery: design, synthesis and evaluation.
Academic Article Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT.
Academic Article Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology.
Academic Article Pyrrolo[2,3-d]pyrimidine derivatives as inhibitors of RET: Design, synthesis and biological evaluation.
Academic Article Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach.
Academic Article Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases.
Academic Article Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
Academic Article Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
Academic Article An updated patent review of rearranged during transfection (RET) kinase inhibitors (2016-present).
Academic Article Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia.

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  • Proto Oncogenes