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Search Results to Srinivas Ayyadevara

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One or more keywords matched the following items that are connected to Ayyadevara, Srinivas

Item TypeName
Academic Article Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal.
Academic Article Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants.
Academic Article Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans.
Academic Article Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2.
Concept Aging
Academic Article Remarkable longevity and stress resistance of nematode PI3K-null mutants.
Academic Article Diverse Caenorhabditis elegans genes that are upregulated in dauer larvae also show elevated transcript levels in long-lived, aged, or starved adults.
Academic Article Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes.
Academic Article Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan.
Academic Article Quantitative trait loci define genes and pathways underlying genetic variation in longevity.
Academic Article Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles.
Academic Article Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.
Academic Article Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans.
Grant Role of glutathione transferases in life span extension of C. elegans
Grant Early Events in Alzheimer Pathogenesis
Academic Article A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories.
Grant Inference of Common Pathways Underlying Neurodegeneration & Other Age-Progressive Diseases
Academic Article "Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation.

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  • Aging