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Search Results to Timothy Ashby

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One or more keywords matched the following items that are connected to Ashby, Timothy

Item TypeName
Academic Article Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.
Academic Article New enumeration algorithm for protein structure comparison and classification.
Academic Article The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma.
Academic Article Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing.
Academic Article Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
Academic Article A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.
Academic Article Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Academic Article The genomic landscape of plasma cells in systemic light chain amyloidosis.
Academic Article Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma.
Academic Article DNAp: A Pipeline for DNA-seq Data Analysis.
Academic Article Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients.
Academic Article Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53.
Academic Article Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma.
Academic Article BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Academic Article Differential RNA splicing as a potentially important driver mechanism in multiple myeloma.
Academic Article TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use.
Academic Article Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.
Academic Article The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma.
Academic Article Monitoring treatment response and disease progression in myeloma with circulating cell-free DNA.
Academic Article Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials.
Academic Article The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Academic Article Chromothripsis as a pathogenic driver of multiple myeloma.
Academic Article Improving prognostic assignment in older adults with multiple myeloma using acquired genetic features, clonal hemopoiesis and telomere length.
Academic Article High-risk transcriptional profiles in multiple myeloma are an acquired feature that can occur in any subtype and more frequently with each subsequent relapse.
Academic Article Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups.
Academic Article Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers.
Academic Article Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.
Academic Article Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement.
Academic Article Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.
Academic Article The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states.

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