Connection

Announcement

You can now add alternative names! Click here to add other names that you've published under.

Search Results to Keshari Thakali

This is a "connection" page, showing the details of why an item matched the keywords from your search.

Search Results

Thakali, Keshari

One or more keywords matched the following properties of Thakali, Keshari

Property

Value

overview

Currently, many women entering pregnancy are either overweight or obese and it is well-established that exposure to maternal obesity during gestation is associated with increased risk of offspring obesity. In addition, in both humans and animal models, in utero exposure to maternal obesity is associated with increased offspring risk of developing cardiovascular disease. Perivascular adipose tissue (PVAT) is an adipose depot surrounding blood vessels and is an important paracrine regulator of underlying smooth muscle and endothelial cell function. Obesity is associated with the loss of PVAT-mediated anti-contractile properties, thus contributing to obesity-associated vascular dysfunction and hypertension. While studies suggest that PVAT is a key link between obesity and cardiovascular disease, there is a lack of information regarding how maternal nutritional status, dietary factors, and physical activity affect offspring PVAT function and overall vascular reactivity. Our studies will examine how maternal nutrition and physical activity during pregnancy program offspring vascular function and are part of an ACNC systems-based approach to carefully characterize how maternal nutrition and physical activity impact offspring health and well-being.

One or more keywords matched the following items that are connected to Thakali, Keshari

Item Type	Name
Academic Article	Intracellular Ca2+ silences L-type Ca2+ channels in mesenteric veins: mechanism of venous smooth muscle resistance to calcium channel blockers.
Academic Article	The ?3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice.
Academic Article	Postsynaptic density-95 scaffolding of Shaker-type K? channels in smooth muscle cells regulates the diameter of cerebral arteries.
Concept	Muscle, Smooth, Vascular
Concept	Myocytes, Smooth Muscle
Concept	Muscle Contraction
Academic Article	Ion channel remodeling in vascular smooth muscle during hypertension: Implications for novel therapeutic approaches.
Academic Article	Preferential myosin heavy chain isoform B Expression may contribute to the faster velocity of contraction in veins versus arteries.
Academic Article	Big ET-1 processing into vasoactive peptides in arteries and veins.
Academic Article	Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats.
Academic Article	Methyl-beta-cyclodextrin prevents angiotensin II-induced tachyphylactic contractile responses in rat aorta.
Academic Article	Arteries and veins desensitize differently to endothelin.
Academic Article	Endothelin-1-induced contraction in veins is independent of hydrogen peroxide.
Academic Article	17?-estradiol reduces Cav 1.2 channel abundance and attenuates Ca2+ -dependent contractions in coronary arteries.
Grant	L-type calcium channels are silent during depolarization of venous smooth muscle

Search Criteria

Muscles