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Search Results to Anna Radominska-Pandya

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One or more keywords matched the following items that are connected to Radominska-Pandya, Anna

Item TypeName
Academic Article Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7.
Academic Article Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.
Academic Article Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases.
Academic Article Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.
Academic Article Human gastrointestinal sulfotransferases: identification and distribution.
Academic Article Regulation of UDP glucuronosyltransferase genes.
Academic Article Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.
Academic Article A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years.
Academic Article Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.
Academic Article Structure of UDP-glucuronosyltransferases in membranes.
Academic Article Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10.
Academic Article The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.
Academic Article Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.
Academic Article Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.
Academic Article Sulfation of the isoflavones genistein and daidzein in human and rat liver and gastrointestinal tract.
Academic Article Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells.
Academic Article A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors.
Academic Article Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.
Academic Article Preface.
Academic Article Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10.
Academic Article Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans.
Academic Article Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases.
Academic Article UDP-glucuronosyltransferases in human intestinal mucosa.
Academic Article Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.
Academic Article Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide.
Academic Article Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.
Academic Article Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7.
Academic Article The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
Academic Article Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene.
Academic Article Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues.
Academic Article Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors.
Academic Article Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II.
Academic Article 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases.
Academic Article K2 toxicity: fatal case of psychiatric complications following AM2201 exposure.
Academic Article Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds.
Academic Article Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells.
Academic Article Carboxyl residues in the active site of human phenol sulfotransferase (SULT1A1).
Academic Article Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.
Academic Article Targeted metabolomic approach for assessing human synthetic cannabinoid exposure and pharmacology.
Academic Article Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals.
Academic Article Ethylenediamine functionalized-single-walled nanotube (f-SWNT)-assisted in vitro delivery of the oncogene suppressor p53 gene to breast cancer MCF-7 cells.
Academic Article Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells.
Academic Article Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism.
Academic Article Sulfaphenazole and a-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice.
Academic Article Photoaffinity labeling of human retinoid X receptor beta (RXRbeta) with 9-cis-retinoic acid: identification of phytanic acid, docosahexaenoic acid, and lithocholic acid as ligands for RXRbeta.
Academic Article Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.
Academic Article Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases.
Academic Article CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen.
Academic Article Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element.
Academic Article Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.
Academic Article Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine.
Academic Article Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use.
Academic Article Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6.
Academic Article Critical role of diacylglycerol- and phospholipid-regulated protein kinase C epsilon in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol.
Academic Article Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved.
Academic Article An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
Academic Article 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7.
Academic Article Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases.
Academic Article Direct photoaffinity labeling of cellular retinoic acid-binding protein I (CRABP-I) with all-trans-retinoic acid: identification of amino acids in the ligand binding site.
Academic Article Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine.
Academic Article Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens.
Academic Article Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10.
Academic Article Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands.
Academic Article Photoaffinity labeling probe for the substrate binding site of human phenol sulfotransferase (SULT1A1): 7-azido-4-methylcoumarin.
Academic Article Glucuronidation of estrogens and retinoic acid and expression of UDP-glucuronosyltransferase 2B7 in human intestinal mucosa.
Academic Article Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes.
Academic Article Structural and functional studies of UDP-glucuronosyltransferases.
Academic Article Direct interaction of all-trans-retinoic acid with protein kinase C (PKC). Implications for PKC signaling and cancer therapy.
Academic Article Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis.
Academic Article Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin.
Academic Article Variability of human hepatic UDP-glucuronosyltransferase activity.
Concept Humans
Academic Article Special issue: nanotechnology and disease.
Academic Article Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases.
Academic Article Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to ?(9)-THC: mechanism underlying greater toxicity?
Academic Article The effect of inhibitors, structurally related to UDP-glucuronic acid, on human recombinant UGT1A10
Academic Article Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaffinity labeling of fusion proteins
Academic Article Gambogic acid and its analogues are novel substrates for human UDP-glucuronosyltransferase and bind cannabinoid receptors CB1 and CB2
Academic Article The glucuronidation of native and oxidized estrogens can be effectively inhibited by compounds structurally related to UDP-glucuronic acid in human recombinant UGT1A10
Academic Article Human UDP-Glucuronosyltransferases: Role in modulation of pancreatic cancer cell proliferation and drug toxicity
Academic Article Application of 5-azido-UDP-glucuronic acid for the characterization of human liver microsomal UDP-glucuronosyltransferase
Academic Article Glucuronidation of arachidonic acid 20-HETE and prostagladin E2 by human hepatic and intestinal UDP-glucuronosyltransferases and recombinant UGT2B7
Academic Article Glucuronidation of Warfarin Metabolites by human Recombinant UDP-Glucuronosyltransferases (UGTs)
Academic Article Estradiol regulates the expression of UDP-glucuronosyltransferase 1A10 in normal and malignant human breast cells
Academic Article Effect of high pressure treatment on the properties of human liver microsomal UDP-glucuronosyltransferase
Academic Article Identification of Substrate Binding Sites of Human UGT1A10; Implication for Multiple Binding Sites
Academic Article The effects of inhibitors structurally related to UDP-glucuronic acid on human recombinant UGT2B7 expreesesd in HK293 cells
Academic Article Human UGT2B7:Nuclear localization by immunofluorescence and immunogold labeling
Academic Article Identification and Characterization of the UDP-glucuronic Acid and Substrate Binding Sites of Human UDP-glucuronosyltransferases: Crystallization and Photoaffinity Labeling
Academic Article Alternative transcript-specific expression for human PXR correlates with the expression for human PXR correlates with the expression of UGT2B7 in human liver and intestine
Academic Article Characterization of mutation in the 395DQxD398 motif of the glucuronic acid binding site in human UGT1A6: Comparison to UGT1A10
Academic Article Characterization of UDP-glucuronic acid binding site of recombinant human liver UGT1*6 by the photoaffinity labeling and proteolytic mapping
Academic Article Steroid glucuronidation in human intestine
Academic Article A structure and reaction mechanism of human UDP-glucuronosyltransferases
Academic Article Sulfotransferases in human intestinal tract
Academic Article constitutive expression of human UDP-glucuronosyltranseferases 2B7 neuyralizes the anti-proliferative effect of retinoic acod in cell culture
Academic Article Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4
Academic Article Human liver UDP-glucuronosyltransferases 8th international Colloquium Biologie Prospectives:Drug Metabolizing Enzymes in man
Academic Article Human UDP-glucuronosyltransferases: A Novel Role in Modulating Cytotoxicity in Cancer
Academic Article Glucuronidation of the 6 -hydroxylated bile acids, hyocholic and hyodeoxycholic acids by human liver microsomes Hepatology 6:1171
Academic Article Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process
Academic Article Phenylalanine90 is a crucial amino acid localized with the phenol binding site of human UDP-glucuronosyltransferases 1A10 as determined by photoaffinity labeling mass spectrometry and site directed mutagenesis
Academic Article In vitro glucuronidation of conventional and 6-hydroxylated bile acids by the rat and human liver microsomes
Academic Article Human UDP-glucuronosyltransferases UGTs) 1A3 and 1A4 are induced by ligands of the aryl hydrocarbon receptor (AhR)
Academic Article Photoaffinity labeling of the aglycon binding site of the human recombinant UDP-glucuronosyltransferase UGT1A6 and phenol sulfotransferase P-PST with 7-azido-4-methylcoumarin
Academic Article Simultaneous glucuronidation of native and oxidized estrogens and warfarin by human recombinant UGT1A10: Potential for drug-drug interactions
Academic Article Glucuronidation of retinoic acid and 4-OH-RA by human liver microsomes and recombinant UGT proteins
Academic Article Human UGT2B7: Nuclear localization by immunofluorescence and immunogold labeling
Academic Article Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6
Academic Article Fluorescent photoaffinity labeling of the human phenol sulfotransferase P-PST by 7-azido-4-methylcoumarin
Academic Article Studies on the substrate specificity of human intestinal UDP-glucuronosyltransferases 1A8 and 1A10
Academic Article Cytochromes P450 involved in the 6-hydroxylation of the bile acids in rats and humans
Academic Article Bile acid hydroxylation by human liver microsomes and vaccinia-virus expressed cytochrome P-450 hPCN1 and hPCN3
Academic Article Independent regulation of 1A and 2B UGT expression and UGT2B7/PXR correlated expression in human livers
Academic Article Separation and Glucuronidation of R- and S-Hydroxywarfarins by Human Recombinant UDP-Glucuronosyltransferases (UGTs)
Academic Article Glucurodination of N-hydroxy-2-amino-1-methyl-6phenylimidazo{4,5-b}pyridine (N-OH-PhlP) by human intestinal microsomes
Academic Article Regulation of the Human UDP-glucuronosyltransferases 2B7
Academic Article Bile acid hydroxylation by human liver microsomes and vaccine virus-expressed cytochrome P-450 hPCN1 and hPCN3
Academic Article Overview: Cyrstallography, modeling and catalytic activity of human UDP-glucuronosyltransferases
Academic Article Glucuronidation of arachidonic acid, 20-HETE and prostaglandin E2 by human hepatic and intestinal UDR-glucuronosyltransferases and recombinant UGT2B7
Academic Article Biosynthesis of oxidized fatty acids and prostaglandins by human UDP-Glucuronosyltransferases
Academic Article Human UDP-glucuronosyltransferases involved in estrogen glucuronidation: kinetic and estrogen biniding site
Academic Article Biotransformation of Abused Synthetic Cannabinoids, JWH-018 and JWH-073, by Human Cytochromes P450 and UDP-glucuronosyltransferases
Academic Article Human UDP-glucuronosyltransferases (UGTs) are involved in the metabolism of the natural resveratrol analogues arachidin-1, arachidin-3 and piceatannol
Academic Article Glucuronidation of bile acid and retinoids by the rat and human liver and intestinal microsomes
Academic Article Biotransformation of abused synthetic cannabinoids in K2/Spice by human hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs)
Academic Article Glucuronidation of fatty acid and their oxidized derivatives by human UDP-glucuronosyltransferases
Academic Article Comparative characterization of UDP-glucuronic acid (UDP-GlcUA) binding-site directed inhibitors with human UGT2B7 and 1A10
Academic Article Glucuronidation of fatty acids and their oxidize derivatives by human UDO-glucuronosylttransferases
Academic Article Production and characterization of catalytically active human liver UDP-glucuronosyltransferase as a fusion protein in E coli
Academic Article Oxidation of abused synthetic cannabinoids in K2/Spice by human cytochromes P450
Academic Article Qualitative and quantitative analysis of lipids from human cerebrospinal fluid under normal conditions and in pathology of CNS
Academic Article Glucuronidation of estrogens by human intestinal microsomes
Academic Article Human bile acid sulfotransferase
Academic Article Biosynthesis of glucosides of 6-hydroxylated bile acid by UDP-sugar-dependent mechanism in human liver microsomes
Academic Article Characterization of UDP-glucuronosyltransferases in normal and carcinogenic human breast tissue
Academic Article Transport of 5-azido-UDP-glucuronic acid into human and rat liver microsomes and photolabeling of UDP-glucuronosyltransferases
Academic Article Photoaffinity labeling of human Reecombinant Retinoid X Receptor with 9-cis-Retinoic acid
Academic Article Phe90 is a crucial amino acid within the estrogen biniding site of the human UDP-glucuronosyltransferase 1A10
Academic Article The role and expression of UGT2B7 in the GI tract and human brain
Academic Article Cloning and Expression of three human intestinal UDP-glucuronosyltransferases(UGTs): 1A5, 1A8, and 1A10
Academic Article Human UDP-Glucuronosyltransferases: Role in modulation of breast cancer cell proliferation and drug toxicity
Academic Article Human UDP-glucuronosyltransferases: A Novel Role in Modulating Cytotoxicity in Cancer
Academic Article Fluorescent photoaffinity labeling of human phenol sulfotransferase by 7-azido-4-metnylcoumarin
Academic Article Biosynthesis of glucuronides of oxidized fatty acids and prostaglandins by human UDP-glucuronosyltransferases
Academic Article Mono- and Di-hydroxylated fatty acid derivatives are novel substrates for human microsomal and recombinant UDP-glucuronosyltransferases
Academic Article A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-O-glucosides of bile acids in human liver microsomes
Academic Article Purification and characterization of a catalytically active human liver UDP-glucuronosyltransferase expressed as a fusion protein in E. coli
Academic Article Glucuronidation of Hydroxylated Derivatives of Warfarin by Human UGT1A10; Identification of Amino acid Motif Involved in Warfarin Binding
Academic Article Affinity labeling of the human recombinant UDP-glucuronosyltransferases UGT*6 with an aldehyde derivative of UDP-glucuronic acid
Academic Article Glucuronidation of catechols in human gastrointestinal tract and recombinant UGTs
Academic Article The Aspartic Acid Of the DxxD Motif Within The C-Terminal region Of Human UDP-Glucuronosyltransferase 1A10 is Critical To The Binding of UDP-Glucuronic Acid
Academic Article UDP-glucuronosyltransferase activity in human intestinal microsomes
Academic Article Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs
Academic Article Separation and Glucuronidation of R- and S-Hydroxywarfarins by Human Recombinant UDP-Glucuronosyltransferases (UGTs)
Academic Article Human UDP-Glucuronosyltransferases: Role in modulation of breast cancer cell proliferation and drug toxicity
Academic Article Substrate binding and specificity of human UGT 1A10
Academic Article Inhibitors of cell proliferation mediated by human UDP-glucuronosyltransferases 2B7(UGT2B7)
Academic Article Affinity labeling of a the human recomibinant UDP-glucuronosyltransferases UGT1*6 with UDP-glucuronic acid analogs
Academic Article Human Metabolism of JWH-018 and JWH-073 and In Vitro Characterization of Major Omega and Omega-1 Metabolites
Academic Article The hydroxylation of bile acids by human liver microsomes
Academic Article Photoaffinity labeling of human recombinant sulfotransferases with 2-azidoadenosine 3',5'-[5'-32P]bisphosphate
Academic Article Specificity and purification of human hepatic UDP-glucuronosyltransferases acting on monohydroxylated short-chain bile acids Hepatology 6:1171
Academic Article Identification of the binding site of the human recombinant UDP-glucuronosyltransferases UGT1A6 by photoaffinity labeling
Academic Article alteration of UDP-glucuronosyltransferase expression in malignant human breast tissue
Academic Article Conjugation of synthetic cannabinoids in K2/Spice by human UDP-glucuronosyltransferase (UGTs)
Academic Article Nuclear receptor activation of drug metabolism enzymes in humans and C elegans
Academic Article Human Hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs) enzymes involved in the metabolism of cannabinoids
Academic Article Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid
Academic Article Glucuronidation of fatty acids and prostaglandins by human UDP-glucuronosyltransferases in Drug Metabolism and Transport
Academic Article Linoleic acid diols: Novel substrate for human liver UDP-glucuronosyltransferases
Academic Article Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells.
Academic Article A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives.
Academic Article Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
Academic Article Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development.
Academic Article Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants.
Academic Article Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice.
Grant STRUCTURE-FUNCTION OF HUMAN UDP-GLUCURONOSYLTRANSFERASES
Grant Glucuronidation of Fatty Acids by Human ER &Nuclear UGT
Grant Synthetic Cannabinoid Toxicity: Role of Biotransformation
Grant HUMAN HEPATIC &INTESTINAL UDP GLUCURONOSYLTRANSFERASES
Grant UDP-GLCUA TRANSFERASES--SPECIFIC UDP-GLCUA TRANSPORTER
Academic Article Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22).
Academic Article Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135).
Academic Article Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity.
Academic Article Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics.
Academic Article Formate assay in body fluids: application in methanol poisoning.
Academic Article Maintenance antipsychotic therapy: is the cure worse than the disease?
Academic Article The effect of o-salicylate upon pentose phosphate pathway activity in normal and G6PD-deficient red cells.
Academic Article Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development.

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