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Search Results to Anna Radominska-Pandya

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One or more keywords matched the following items that are connected to Radominska-Pandya, Anna

Item TypeName
Academic Article Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.
Academic Article Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7.
Academic Article Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression.
Academic Article Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases.
Academic Article Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.
Academic Article Regulation of UDP glucuronosyltransferase genes.
Academic Article Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.
Academic Article A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years.
Academic Article Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.
Academic Article Structure of UDP-glucuronosyltransferases in membranes.
Academic Article Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10.
Academic Article The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.
Academic Article Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity.
Academic Article Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.
Academic Article Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells.
Academic Article A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors.
Academic Article Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.
Academic Article Preface.
Academic Article Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10.
Academic Article Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans.
Academic Article Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases.
Academic Article UDP-glucuronosyltransferases in human intestinal mucosa.
Academic Article Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.
Academic Article Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide.
Academic Article Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.
Academic Article Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7.
Academic Article The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
Academic Article Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene.
Academic Article Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues.
Academic Article Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors.
Academic Article Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II.
Academic Article 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases.
Academic Article Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved.
Academic Article Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells.
Academic Article Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.
Academic Article Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases.
Academic Article Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element.
Academic Article Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.
Academic Article Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use.
Academic Article Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6.
Academic Article Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved.
Academic Article 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7.
Academic Article Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases.
Academic Article Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens.
Academic Article Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10.
Academic Article Glucuronidation of estrogens and retinoic acid and expression of UDP-glucuronosyltransferase 2B7 in human intestinal mucosa.
Academic Article Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes.
Academic Article Structural and functional studies of UDP-glucuronosyltransferases.
Academic Article Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis.
Academic Article Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin.
Academic Article Variability of human hepatic UDP-glucuronosyltransferase activity.
Concept Glucuronosyltransferase
Academic Article Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases.
Academic Article Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaffinity labeling of fusion proteins
Academic Article Gambogic acid and its analogues are novel substrates for human UDP-glucuronosyltransferase and bind cannabinoid receptors CB1 and CB2
Academic Article inhibitors and characterization of the active site of UDP-glucuronosyltransferase UGT*6
Academic Article Application of 5-azido-UDP-glucuronic acid for the characterization of human liver microsomal UDP-glucuronosyltransferase
Academic Article Estradiol regulates the expression of UDP-glucuronosyltransferase 1A10 in normal and malignant human breast cells
Academic Article Effect of high pressure treatment on the properties of human liver microsomal UDP-glucuronosyltransferase
Academic Article Isolation of UDP-glucuronosyltransferase clones using specific PCR-generated probes
Academic Article Comparison of bile acid glucuronidation activity in various species; solubilzation of rabbit liver caboxyl-directed bile acid UDP-glucuronosyltransferase(UDP-GT). FASEB J, 2:A581
Academic Article Targeted nanoparticle delivery of tumor suppressing UDP-glucuronosyltransferase (UGT) genes into cancer cells
Academic Article Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4
Academic Article Glucuronidation of all-trans-retinoic acid and 5,6-epoxy-all-trans-retinoic acid. Activation of rat liver microsomal UDP-glucuronosyltransferase activity by alamethicin
Academic Article Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process
Academic Article Photoaffinity labeling of the aglycon binding site of the human recombinant UDP-glucuronosyltransferase UGT1A6 and phenol sulfotransferase P-PST with 7-azido-4-methylcoumarin
Academic Article Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6
Academic Article Biotransformation of abused synthetic cannabinoids in K2/Spice by human hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs)
Academic Article Targeted nanoparticle delivery of tumor suppressing p53 and UDP-glucuronosyltransferase (UGT) genes into breast cancer cells
Academic Article Production and characterization of catalytically active human liver UDP-glucuronosyltransferase as a fusion protein in E coli
Academic Article Application of photoaffinity labeling with [11,12-3H]all-trans-retinoic acid to characterization of rat liver microsomal UDP-glucuronosyltransferase(s) with activity toward retinoic acid
Academic Article Phe90 is a crucial amino acid within the estrogen biniding site of the human UDP-glucuronosyltransferase 1A10
Academic Article Purification and characterization of a catalytically active human liver UDP-glucuronosyltransferase expressed as a fusion protein in E. coli
Academic Article The Aspartic Acid Of the DxxD Motif Within The C-Terminal region Of Human UDP-Glucuronosyltransferase 1A10 is Critical To The Binding of UDP-Glucuronic Acid
Academic Article UDP-glucuronosyltransferase activity in human intestinal microsomes
Academic Article Identification of the recombinant UDP-glucuronosyltransferase 2B7 in nuclear envelops
Academic Article Isolation of UDP-glucuronosyltransferase clones using specific PCR-generated probes
Academic Article alteration of UDP-glucuronosyltransferase expression in malignant human breast tissue
Academic Article Conjugation of synthetic cannabinoids in K2/Spice by human UDP-glucuronosyltransferase (UGTs)
Academic Article Human Hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs) enzymes involved in the metabolism of cannabinoids
Academic Article Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid
Academic Article Similarities between chtochrome P450 (CYP)2C1 and UDP-glucuronosyltransferase (UGT)1A10 phenol active site residues as identified by photoaffinity labeling (PAL), MS, and homology modeling
Academic Article A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives.
Academic Article Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
Grant HUMAN HEPATIC &INTESTINAL UDP GLUCURONOSYLTRANSFERASES
Academic Article Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22).

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  • Glucuronosyltransferase