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Search Results to Joshua Kennedy

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Kennedy, Joshua

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Dr. Kennedy received his medical degree from UAMS in 2006 and completed an Internal Medicine and Pediatrics residency from 2006 to 2010. He went on to complete a fellowship in Allergy and Immunology at the University of Virginia. Dr. Kennedy joined the faculty of UAMS in July 2013 where he is a member of the Division of Pediatric Allergy and Immunology and the ACRI Lung Cell Biology Lab. Dr. Kennedy’s primary research focuses upon mechanisms whereby infection with the common cold virus, rhinovirus (RV), leads to exacerbations of asthma. 60% to 80% of children seen in the emergency room with an exacerbation of asthma will be infected with RV. In his previous research, it became clear that while RV infection alone increases the risk of wheezing in children with asthma; the combination of RV infection and high titer sensitization to allergen significantly increases the odds to wheeze in children seen in the emergency department. It is this synergy between allergy and RV infection that drives his current research hypotheses. To that end, he is studying epithelial cell-derived cytokines that bias a Th2 (i.e., allergic) response (IL-33, IL-25, and TSLP) associated with RV infection in subjects with asthma both in vitro and in vivo. Also, Dr. Kennedy enthusiastically contributes to the education of fellows, residents, and students at UAMS by participating in the educational mission of the Department of Pediatrics in many capacities.

One or more keywords matched the following items that are connected to Kennedy, Joshua

Item Type	Name
Concept	Rhinovirus
Academic Article	Rhinovirus-induced asthma exacerbations during childhood: the importance of understanding the atopic status of the host.
Academic Article	Comparison of viral load in individuals with and without asthma during infections with rhinovirus.
Academic Article	Pathogenesis of rhinovirus infection.
Academic Article	High titers of IgE antibody to dust mite allergen and risk for wheezing among asthmatic children infected with rhinovirus
Academic Article	Rhinovirus and asthma: a storied history of incompatibility.
Academic Article	High titers of IgE antibody to dust mite allergen and risk for wheezing among asthmatic children infected with rhinovirus.
Academic Article	Infection with human rhinovirus 16 promotes enhanced IgE responsiveness in basophils of atopic asthmatics.
Academic Article	Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices.
Academic Article	Modulation of airway hyperresponsiveness by rhinovirus exposure.
Grant	“Mechanisms for Rhinovirus Induced Airway Hyper-responsiveness in Human Lung.”
Grant	“Examining the intersection of rhinovirus infection and asthma exacerbations.”
Academic Article	Rhinovirus and Asthma Exacerbations.
Academic Article	Rhinovirus C15 Induces Airway Hyperresponsiveness via Calcium Mobilization in Airway Smooth Muscle.
Academic Article	Understanding the asthmatic response to an experimental rhinovirus infection: Exploring the effects of blocking IgE.
Academic Article	Lower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity.
Academic Article	Cluster analysis of nasal cytokines during rhinovirus infection identifies different immunophenotypes in both children and adults with allergic asthma.
Academic Article	T-helper 2 mechanisms involved in human rhinovirus infections and asthma.

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Rhinovirus