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Search Results to Stavros Manolagas

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One or more keywords matched the following items that are connected to Manolagas, Stavros

Item TypeName
Academic Article Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids.
Academic Article The skeletal effects of glucocorticoid excess override those of orchidectomy in mice.
Academic Article Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs.
Academic Article Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.
Academic Article Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism.
Academic Article Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength.
Academic Article Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation.
Academic Article Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor.
Academic Article Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases.
Academic Article Quantifying osteoblast and osteocyte apoptosis: challenges and rewards.
Academic Article Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts.
Academic Article Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.
Academic Article Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice.
Academic Article Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo.
Academic Article Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha.
Academic Article FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice.
Academic Article Glucocorticoids and tumor necrosis factor a increase oxidative stress and suppress Wnt protein signaling in osteoblasts.
Academic Article A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction.
Academic Article Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton.
Academic Article Commitment to the osteoblast lineage is not required for RANKL gene expression.
Academic Article Control of bone mass and remodeling by PTH receptor signaling in osteocytes.
Academic Article Steroids and osteoporosis: the quest for mechanisms.
Academic Article Suppression of autophagy in osteocytes mimics skeletal aging.
Academic Article Matrix-embedded cells control osteoclast formation.
Academic Article Sex steroids and bone.
Academic Article Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids.
Academic Article Estrogen receptor-a signaling in osteoblast progenitors stimulates cortical bone accrual.
Academic Article The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone.
Academic Article Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts.
Academic Article Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.
Academic Article Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age.
Academic Article Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation.
Academic Article Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms.
Concept Osteoblasts
Academic Article Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates bone porosity with age
Academic Article Suppression of Autophagy in Osteoblasts and Osteocytes Increases Oxidative Stress and Recapitulates the Effects of Aging on the Murine Skeleton
Academic Article Glucocorticoids and tumor necrosis factor alpha increase oxidative stress and suppress Wnt protein signaling in osteoblasts
Academic Article Estrogen receptor-alpha signaling in osteoblast progenitors stimulates cortical bone accrual
Academic Article The ERa of Osteoblast Progenitors is Required for Normal Accrual of Cortical Bone Mass Independently of Estrogens
Academic Article Sirtuin1 (Sirt1) promotes cortical bone formation by preventing ?-catenin sequestration by FoxO transcription factors in osteoblast progenitors.
Academic Article The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERa Signaling in Osteoblasts and Osteoclasts.
Academic Article Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone.
Academic Article Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice.
Academic Article Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes.
Academic Article DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age.
Academic Article Old age causes de novo intracortical bone remodeling and porosity in mice.
Academic Article The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice.
Academic Article Oxidation-specific epitopes restrain bone formation.
Grant OSTEOBLAST COMMITMENT AND DIFFERENTIATION BY ANGELS
Grant Molecular and Cellular Mechanisms of Osteoporosis
Grant Androgens, estrogens, and bone loss in males
Academic Article Cxcl12 Deletion in Mesenchymal Cells Increases Bone Turnover and Attenuates the Loss of Cortical Bone Caused by Estrogen Deficiency in Mice.
Academic Article Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency.
Academic Article Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass.
Academic Article Retraction: Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass.

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