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Search Results to Alan Tackett

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One or more keywords matched the following properties of Tackett, Alan

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overview My laboratory focuses on histone epigenetic mechanisms that regulate gene transcription and that are coupled to melanoma progression. We utilize a suite of techniques in our studies including proteomics of human biopsies, immunohistochemistry, cell culture, tumorigenicity assays, ChIPseq, biochemical and proteomic approaches for analyses of protein complexes, and cutting-edge mass spectrometry for the analysis of histone post-translational modifications. We have a unique environment that provides for discovery-based studies like proteomics as well as hypothesis-driven studies like those we perform in cell culture and with skin biopsies. In addition to our melanoma work, we develop new technologies for epigenetic studies such as tools for detection of in vivo protein interactions and quantitative assays for histone modifying proteins.

One or more keywords matched the following items that are connected to Tackett, Alan

Item TypeName
Academic Article Proteomic and genomic characterization of chromatin complexes at a boundary.
Academic Article I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions.
Academic Article A quantitative proteomic analysis of FFPE melanoma.
Academic Article Purification of a specific native genomic locus for proteomic analysis.
Concept Proteomics
Academic Article Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma
Academic Article A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Academic Article Purification of specific chromatin loci for proteomic analysis.
Academic Article The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.
Academic Article Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway.
Academic Article Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
Academic Article Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles.
Academic Article Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.
Academic Article Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus.
Academic Article A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates.
Academic Article Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide.
Academic Article A Proteomic Study of Human Merkel Cell Carcinoma.
Academic Article Proteomic Findings in Melanoma.
Academic Article Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma.
Academic Article Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection.
Academic Article CD109 Overexpression in Pancreatic Cancer Identified by Cell-Surface Glycoprotein Capture.
Academic Article Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break.
Academic Article Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1.
Academic Article Microscopes and Mass Spectrometers.
Academic Article Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol.
Academic Article Impact of Spaceflight and Artificial Gravity on the Mouse Retina: Biochemical and Proteomic Analysis.
Academic Article Proteomics and melanoma: a current perspective.
Academic Article Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome.
Academic Article Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot.
Academic Article Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats.
Grant Partnerships for Biomedical Research in Arkansas
Grant Technology for Identification of Epiproteomes in Tissue Samples
Grant Transgenic analysis of platelet receptor expression
Academic Article Proteomic characterization of the arsenic response locus in S. cerevisiae.
Grant Epigenetic regulation of metabolic stress pathways in melanoma infiltrating lymphocytes- Resubmission
Academic Article Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations.
Grant Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer
Academic Article Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis.
Academic Article Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags.
Academic Article ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data.
Grant IDeA National Resource for Quantitative Proteomics
Academic Article MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas.
Academic Article Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma.
Grant IDeA National Resource for Quantitative Proteomics

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