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Search Results to Steven Post

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One or more keywords matched the following properties of Post, Steven

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research overview The goal of our research is to better understand the key role that macrophages play in the development and progression of chronic inflammatory diseases including cardiovascular disease and cancer. Our studies indicate that a specific macrophage receptor, the class A macrophage scavenger receptor (SR-A), may differentially function to enhance or diminish inflammation. Our ongoing studies seek to provide mechanistic details regarding the functional interactions between SR-A and inflammatory signaling pathways. Results of these studies will advance understanding of the pathologic role of macrophages in cardiovascular disease and cancer, and may indicate novel therapeutic approaches targeting the inflammatory responses in these disease.

One or more keywords matched the following items that are connected to Post, Steven

Item TypeName
Academic Article Macrophage colony-stimulating factor differentially regulates low density lipoprotein and transferrin receptors.
Academic Article SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.
Academic Article Class A scavenger receptors mediate cell adhesion via activation of G(i/o) and formation of focal adhesion complexes.
Academic Article Class A scavenger receptor-mediated cell adhesion requires the sequential activation of Lyn and PI3-kinase.
Academic Article Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.
Academic Article Regulation of class A scavenger receptor-mediated cell adhesion and surface localization by PI3K: identification of a regulatory cytoplasmic motif.
Academic Article Regulation of acetylated low density lipoprotein uptake in macrophages by pertussis toxin-sensitive G proteins.
Academic Article SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation.
Academic Article Macrophage colony-stimulating factor rapidly enhances beta-migrating very low density lipoprotein metabolism in macrophages through activation of a Gi/o protein signaling pathway.
Concept Macrophages, Peritoneal
Concept Macrophage Colony-Stimulating Factor
Concept Macrophage-1 Antigen
Concept Macrophages
Academic Article Platelet glycoprotein Ib-IX as a regulator of systemic inflammation.
Academic Article Lipid rafts couple class A scavenger receptors to phospholipase A2 activation during macrophage adhesion.
Academic Article Prostaglandins produced during class A scavenger receptor-mediated macrophage adhesion differentially regulate cytokine production.
Academic Article Cleavage of Type I Collagen by Fibroblast Activation Protein-a Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion.
Grant Fibroblast-macrophage interactions induce a tumor-promoting microenvironment
Academic Article Identification of a novel monocytic phenotype in Classic Hodgkin Lymphoma tumor microenvironment.
Grant Fibroblast-macrophage interactions induce a tumor-promoting microenvironment

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  • Macrophages