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research overview Current Research Support: NSF Award Iasemidis (PI) 9/16–Present Title: EPSCoR NeuroNem NCE Role: Co–Investigator (5%) RII Track-2 FEC-Probing and understanding the brain: micro and macro dynamics of seizure and memory networks This project is an interdisciplinary and multi-site collaboration of neuroscientists, engineers and medical professionals that will probe brain function at molecular, cellular and macro-levels in epileptic rats and human subjects with the goal of identifying epileptic and memory networks in interictal periods, monitor their dynamical behavior and study their transition to seizure. Completed Research Support: NIGMS P30 Virmani (PI) 05/17–04/19 Title: Modafinil as a novel treatment for freezing of gait in Parkinson’s disease Role: Co-Investigator UAMS TRI Pilot Award Kleiner (PI) 09/12–03/14 UL1TR000039 Title: Functional MRI Predictive of Cognitive Risk in DBS Role: Principal Investigator UAMS Medical Research Endowment Petersen (PI) 01/12–11/13 Cognitive and fMRI Biomarkers in Obsessive Compulsive Disorder Role: Co-Investigator KL2 TR000063 James (PI) 08/11–08/12 Title: Predicting treatment response to surgical resection in epilepsy with functional neuroimaging Role: Mentor Internal Pilot Funding James (PI) 06/11–09/11 Title: The Cognitive Connectome Role: Co-Investigator R01DA024080 Bickel (PI) 12/07–11/12 Title: Executive Function Therapy for Stimulant Addiction Role: Co-Investigator R18DP001145 West/Beck (Co–PIs) 09/07–09/11 Center for Disease Control Title: Translation of Obesity and Cognition Research in a Rural State via Senior Centers Role: Co-Investigator Other Support: 4/04 APA Advanced Training Institute Grant Advanced Training in fMRI Charleston, MA Peer Reviewed Publications: *DeGeorge, E, Fullen, C, Gess, J, Kleiner, J, & Larson-Prior, L (2021). Effects of age of onset and medication on cognitive performance and quality of life in patients with epilepsy. Epilepsy & Behavior. *James GA, Kearney-Ramos TE, Young JA, Kilts CD, Gess JL, Fausett JS. (2016). Functional independence in resting-state connectivity facilitates higher-order cognition. Brain and Cognition, 105: 78–87. PMID: 27105037 Fausett, J. S., Gilmore–Szott, E., & Hester, M. (2015). Networking ethics: A survey of bioethics networks across the US. Healthcare Ethics Consortium. *Kearney-Ramos, T. Fausett, J., Gess, J., Reno, A., Peraza, J., Kilts, C., & James, GA. (2014). Merging clinical neuropsychology and functional neuroimaging to evaluate the construct validity and neural representation of the n-back task. Journal of the International Neuropsychological Society. *Gess, J., Fausett, J., Kearney-Ramos, T., Kilts, C., & James, G. A. (2014). Task- dependent recruitment of resting state networks reflective normative variance in cognition. Brain & Behavior. Felix H.C., Adams B, Cornell C, Fausett J., Krukowski R.A., Love S.J., Prewitt T.E., & West DS. (2014). Barriers and facilitators to senior centers participating in translational research, Research on Aging, 36(1), 22–38 Edmondson, D., Richardson, S., Fausett, J., Falzon, L., Toledo, B., & Kronish, I. (2013). Prevalence of PTSD in survivors of stroke and transient ischemic attack: A Meta-Analytic Review. PLoS ONE. Beck, C., Fausett, J., Krukowski, R., Cornell, C., Prewitt, T.E., Lensing, S., Bursac, Z., Felix, H., Love, S., McDougall, G., & West, D. (2013). A community-based, lay health educator delivered cognitive intervention for obese senior adults. Journal of Aging and Health Felix, H., Adams, B., Kleiner Fausett, J., Krukowski, B., Prewitt, T.E., & West, D. (2012). Calculating reach of evidence-based weight loss and memory improvement interventions among older adults attending Arkansas senior centers, 2008–2011. Preventing Chronic Disease. 9:110141. DOI: http://dx.doi.org/10.5888/pcd9.110141 West, D., Bursac, Z., Cornell, C., Felix, H., Kleiner, J., Krukowski, R., Love, S., Prewitt, E., & Beck, C. (2011). Randomized trial of lay health educators translating an evidenced based weight loss intervention to obese older adults in rural senior centers. American Journal of Preventative Medicine, 41(4), 385–391. Brewin, C., Kleiner, J.S., Vasterling, J.J., & Field, A. (2007). Memory for emotionally neutral information in posttraumatic stress disorder: A meta-analytic investigation. Journal of Abnormal Psychology, 116(3), 448–463. O’Bryant, S.E., Engle, L., Kleiner, J.S., Vasterling, J.J., & Black, F.W. (2007). TOMM Trial 1 as a screening instrument for insufficient effort. The Clinical Neuropsychologist, 21(3), 511–521. Grohman, K., Donnelly, K., Strang, J., & Kleiner, J.S. (2002). Neuropsychological impairment in veterans who are HIV-positive. Brain & Cognition, 49(2), 194–198. Strang, J., Donnelly, K., Grohman K., & Kleiner, J.S. (2002). Verbal learning and visuomotor attention: Alzheimer’s disease and geriatric depression. Brain & Cognition, 49(2), 216–220. Under Review: Invited Presentations: Kleiner, J. (2011). Traumatic Brain Injury. Invited presentation to the Psychiatric Research Institute Board of Directors, University of Arkansas for Medical Sciences. Kleiner, J. (2010). Neuropsychological Assessment. Invited presentation to the Psychiatric Research Institute Board of Directors, University of Arkansas for Medical Sciences. Kleiner, J (2010). Neuropsychological Assessment. Invited Grand Rounds to the Department of Neurology, University of Arkansas for Medical Sciences. Kleiner, J (2006). Neuropsychological Assessment. Invited Grand Rounds to the Department of Neurology, University of Arkansas for Medical Sciences. Peer Reviewed Abstracts: *Peraza, J., Gess, J. L., Fausett, J. S., Reno, A. J., Kearney-Ramos, T., & James, G. A. (2013). Emotional regulation and change in brain response from novel to familiar emotional images. Journal of the International Neuropsychological Society, 19, Supplement S1, 13. doi: 10.1017/S1355617713000362 *Reno, A. J., Fausett, J. S., Gess, J. L., Peraza, J., Kearney-Ramos, T., & James, G. A. (2013). Neural activity and behavioral performance on measures of working memory among healthy subjects. Journal of the International Neuropsychological Society, 19, Supplement S1, 14. doi: 10.1017/S1355617713000362 Donnelly, J.P., Zevon, M.A., Kleiner, J.S., Hoffmann, B.M., Duquin, J.A., Donnelly, K., Jensen, S.L., & McCarthy, P.L., Jr. (2007). Structural analysis of response shift and stability of the FACT-BMT. International Society for Quality of Life Research meeting abstracts [www.isoqol.org/2007mtgabstracts]. The QLR Journal, A-119, Abstract #1698. Duquin, J. A., Donnelly, J. P., Donnelly, K. Z., Kleiner, J. S., Hoffman, B., Englert, J., Zevon, M. A., & McCarthy, P. (2006). A longitudinal investigation of neuropsychological sequelae in blood or marrow transplantation. Journal of Neuropsychiatry and Clinical Neurosciences, 18, 267. Kleiner, J.S., Grohman, K., Donnelly, K., & Strang, J. (2002). Differential diagnosis of AD, VaD, PD, and mild cognitive impairment using the Clock Drawing Test and the Dementia Rating Scale. Journal of the International Neuropsychology Society, 8(2), 197. Grohman, K., Donnelly, K., Kleiner, J.S., & Strang, J. (2002). Memory and olfactory discrimination in posttraumatic stress disorder. Journal of the International Neuropsychology Society, 8(2), 248. Strang, J.S., Donnelly, K. Z., Grohman, K., & Kleiner, J.S. (2001). Attention and working memory in Gulf War Syndrome and depression. Archives of Clinical Neuropsychology, 16(8), 799. Invited Publications: Kleiner, J.S. (2010). Brain Plasticity. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 440–441). New York: Springer. Kleiner, J.S. (2010). Equipotentiality. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 969–970). New York: Springer. Kleiner, J.S. (2010). Parasthesia. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 1859–1860). New York: Springer. Kleiner, J.S. (2010). Peduncular Hallucinosis. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 1895). New York: Springer. Kleiner, J.S. (2010). Right Left Orientation. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2179–2180). New York: Springer. Kleiner, J.S. (2010). Somatotopic Organization. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp.2324–2324). New York: Springer. Kleiner, J.S. (2010). Somesthesia. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2325). New York: Springer. Kleiner, J.S. (2010). Spontaneous Recovery. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2361–2362). New York: Springer. Kleiner, J.S. (2010). Substantia Gelatinosa. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2432–2433). New York: Springer. Kleiner, J.S. (2010). Taste. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2470-2471). New York: Springer. Kleiner, J.S. (2010). Thalamic Pain Syndrome. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2505). New York: Springer. Kleiner, J.S. (2010). Vestibular Dysfunction. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2609–2610). New York: Springer. Kleiner, J.S. (2010). Vestibular System. In Kreutzer, DeLuca and Kaplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 2611–2612). New York: Springer. Book Chapters: Vasterling, J.J. & Kleiner, J.S. (2005). Clinical neuropsychological evaluation. In Vasterling and Brewin (Eds.), Neuropsychology of PTSD: Biological, Clinical, and Cognitive Perspectives. Harcourt Publications. DeLucia–Waack, J.L., Bridbord, K.H., & Kleiner, J.S. (Eds.). (2002). Group Work Experts Share Their Favorite Activities: A Guide to Planning, Conducting, and Processing. Alexandria, VA: Association for Specialists in Group Work. Presentations at Professional Conferences (Peer-Reviewed): *Teti, A., Gess, J., Kleiner, J., Isaac, L., Fullen, C., & Larson-Prior, L. Lateralization in phonemic fluency, not semantic fluency in temporal lobe epilepsy. Poster presented at the 49th International Neuropsychological Society Meeting; February 2021. Virtual. *Isaac, L., Gess, J., Kleiner, J., Kemp, A., & James, G.A., Frontoparietal and salience network activation varies with difficulty on Tower of London Trials. Poster presented at the 49th International Neuropsychological Society Meeting; February 2021. Virtual. *Isaac, L., Fullen, C., Kleiner, J., Kemp, A., Larson-Prior, L., & Gess, J., Mood, but not cognitive functioning predictive of self-reported medication effects in epilepsy. Poster presented at the 48th International Neuropsychological Society Meeting; February 2020. Denver, CO. *Fullen, C., Isaac, L., Gess, J., Kleiner, J., Kemp, A., & Larson-Prior, L. The effect of patient-specific seizure characteristics on perceived cognitive functioning. Poster presented at the 48th International Neuropsychological Society Meeting; February 2020. Denver, CO. *Carns, D., Gess, J., Kleiner, J., Kemp, A., & Larson-Prior, L. Utilization of DKEFS Fluency Measures to Determine Laterality in Epilepsy Patients. International Neuropsychological Society. Poster presented at the 47th International Neuropsychological Society Meeting, February, 2019. *Carns, D., Kleiner, J., Gess, J., Kemp, A., & Larson-Prior, L. Relationship of seizure locality and error rates on the Wisconsin Card Sorting Test. Poster presented at the 47th International Neuropsychological Society Meeting, February, 2019. *Tengowski, L., Salinas, S. L., Kleiner, J. S., Gess, J. L., Kemp, A. S., & Larson-Prior, L. (2019, February). A Task of Visual Integration Can Help Lateralize Seizure Location in Pre-Surgical Epilepsy Candidates. Poster presented at the International Neuropsychological Society 47thAnnual Meeting, New York City, NY. *Salinas, S. L., Kleiner, J. S., Gess, J. L., & James, G. A. (2018, February). Dissociable Patterns of Neural Activity for Semantically and Arbitrarily Related Word Pairs. Poster to be presented at the International Neuropsychological Society 46th Annual Meeting, Washington, D.C. *Giambrone, L., Salinas, S. L., Kemp, A. S., Kleiner, J. S., Gess, J. L., & Larson-Prior, L. (2018, February). Gender Differences on a Test of Spatial Memory Among Patients with Epilepsy. Poster to be presented at the International Neuropsychological Society 46th Annual Meeting, Washington, D.C. *Giambrone, L., Salinas, S. L., Kemp, A. S., Kleiner, J. S., Gess, J. L., & Larson-Prior, L. (2017, July). A Test of Spatial Memory Predicts Lateralization Among Patients with Epilepsy. Poster presented at the Neuronal Networks in Epilepsy and Memory Annual Meeting, Rustin, LA. *Martins BS, Kearney-Ramos TE, Gess JL, Fausett JS, Cisler JM, Kilts CD, James GA. Re-evaluating the Iowa Gambling Task: A New Perspective for an Established Method. Seventy-first Annual Meeting of the Society of Biological Psychiatry, May 12–14, 2016, Atlanta, GA, USA. *James GA, Kearney-Ramos TE, Young JA, Gess JL, Fausett JS, Kilts CD. Resting-state functional connectivity encodes higher-order (but not lower-order) cognitions. Twenty–third Annual Meeting of the Society for Cognitive Neuroscience, April 2–5, 2016, New York, NY, USA. *James GA, Kearney-Ramos TE, Young JA, Gess JL, Fausett JS, Kilts CD. Functional independence of brain regions at rest broadly predicts individual differences in higher-order cognition. American College of Neuropsychopharmacology, December 5–10, 2015, Hollywood, FL, USA. Sullivan S, Fausett JS, Gess JL, James GA. Contribution of extraversion to executive function: a construct validity analysis. International Neuropsychology Society, February 3–6, 2016, Boston, MA, UAMS. *James GA, Kearney-Ramos TE, Young JA, Gess JL, Fausett JS, Kilts CD. (Submitted for Review). Predicting Cognition from Brain Activity: A comparison of Task-based and Resting-state fMRI Methods. *Morais, H., Gess, J.L., Fausett, J., Miller, N., & James, GA. (2015, February). Network Connectivity and Proverb Test Performance. Poster presented at the Annual Meeting of the International Neuropsychological Society, Denver, CO. *Miller, N., Fausett, J., Gess, J.L., Morais, H. & James, GA. (2015, February). Neuroanatomical contributions to planning and the relationship between resting state fMRI and DKEFS Tower Test. Poster presented at the Annual Meeting of the International Neuropsychological Society, Denver, CO. *Kearney-Ramos TE, Fausett JS, Gess JL, Reno A, Peraza J, Kilts CD, James GA. (2014, June) Exploring normative working memory variance to better understand disparities in risk for drug use disorders. Seventy-sixth Annual Scientific Meeting for the College on Problems of Drug Dependence, June 14–19, 2014, San Juan, PR, USA. *Kearney-Ramos, T., Fausett, J., Gess, J., Jones-Reno, A., Peraza, J., Kilts, C., & James, GA. (2014, April). Modeling the neural representation of normative working memory ability through functional neuroimaging and clinical neuropsychology. 21 Annual Meeting of the Society for Cognitive Neuroscience; Boston, MA. *James. GA., Kearney-Ramos, T., Gess, J., Fausett, J., & Kilts, C. (2014, April). The Cognitive Connectome: Mapping the neural representation of normative variance in cognition. 21 Annual Meeting of the Society for Cognitive Neuroscience; Boston, MA. *James. GA., Gess, J., Fausett, J., Kearney-Ramos, T., & Kilts, C. (2013, December). Translating functional neuroimaging into clinical care by understanding normative variance in cognition and neural function: Insights from the Cognitive Connectome. American College of Neuropsychopharmacology; Hollywood, FL. *Kearney-Ramos, T, Fausett, JK, Gess, JL, Reno, A, Peraza, J, Kilts, CD, & James, GA. (2013, November). Defining individual differences in the neural representation of working memory though functional neuroimaging and clinical neuropsychology. Annual Biomedical Research Conference for Minority Students. Nashville, TN. *Gess, JL., Fausett, JK., Kearney-Ramos, T., Kilts, C., & James, GA. (2013, June). Missed It! What does the MSIT truly measure? Poster presented at the Annual Meeting of the Organization for Human Brain Mapping; Seattle, WA. *Kearney-Ramos T, Fausett JS, Gess JL, Reno A, Peraza J, Kilts CD, James GA. (2013, June) Resting connectivity of parietal and parahippocampus predicts visual working memory performance. Poster presented at the Annual Meeting of the Organization for Human Brain Mapping, Seattle, WA. *James, GA., Fausett, JK., Gess, JL., Kearney-Ramos, T., Reno, A., Peraza, J., Greenfield, LJ., & Kilts, CD. (2013, April). Mapping the Cognitive Connectome: Translating functional neuroimaging into personalized medicine. Poster presented at the Translational Science Meeting, Washington DC. *Peraza, J., Gess, JL, Fausett, JK, Reno, AJ, Kearney-Ramos, T., & James, GA (2013). Emotional regulation and change in brain response from novel to familiar emotional images. Poster presented at the Annual Meeting of the International Neuropsychological Society, Waikoloa, Hawaii. *Reno, A., Fausett, J., Gess, J., Peraza, J., Kearney-Ramos, T., & James, G.A. (2013). Neural Activity And Behavioral Performance on Measures of Working Memory Among Healthy Subjects. Poster presented at the Annual Meeting of the International Neuropsychological Society, Waikoloa, Hawaii. Gess, J., Fausett, J., & James, G.A. (2013). Building the Cognitive Connectome: A Case Study with Temporal Lobe Epilepsy. Poster presented at the Annual Meeting of the International Neuropsychological Society, Waikoloa, Hawaii. James GA, Fausett JS, Gess JL, Greenfield LJ & Kilts CD. Building the Cognitive Connectome: Translating functional neuroimaging into personalized medicine. Society for Neuroscience, October 13–17, 2012, New Orleans, LA, USA. James, G.A., Fausett, J.S., Gess, J.L., Greenfield, L.J., and Kilts, C.D. (2012, April). Building the Cognitive Connectome: Translating functional neuroimaging into personalized medicine. Translational Neuroscience Meeting, Washington DC. Beck, C., Kleiner Fausett, J., Krukowski, R., Cornell, C., Prewitt, T.E., Lensing, S., Bursac, Z., Felix, H., Love, S., McDougall, G., & West, D. (2011, November). A Randomized Trial of a Community-Based, Lay Health Educator Delivered Cognitive Intervention. Symposia presentation at the Gerontological Society of America’s 64th Annual Scientific Meeting, Boston, Massachusetts. Kleiner, J.S., Engel, L., O’Bryant, S.E., Vasterling, J.J., & Black, F.W. (2005, October). TOMM Trial 1 as a screening instrument for suboptimal effort. Poster presented at the Annual Meeting of the National Academy of Neuropsychology, Orlando, Florida. Kleiner, J.S., Donnelly, K.Z., Hoffman, B.M., Mordhorst, M.J., & Burhart, J.A. (2004, February). Utility of the TMT B divided by A equation in differential diagnosis of depression and dementia. Poster presented at the Annual Meeting of the International Neuropsychological Society, Baltimore, Maryland. Mordhorst, M.J., Donnelly, K.Z., Burhart, J.A., Hoffman, B.M., & Kleiner, J.S. (2004, February). Semantic clustering: Criterion validity of various indices. Poster presented at the Annual Meeting of the International Neuropsychological Society, Baltimore, Maryland. Burhart, J.A., Donnelly, K.Z., Donnelly, J.P., Kleiner, J.S., Hoffman, B.M., & Mordhorst, M.J. (2004, February). The effects of traumatic brain injury on verbal and visual memory in a veteran sample. Poster presented at the Annual Meeting of the International Neuropsychological Society, Baltimore, Maryland. Kleiner, J.S., Grohman, K., Donnelly, K.Z., & Strang, J. (2002, February). Differential diagnosis of AD, VaD, PD, and mild cognitive impairment using the Clock Drawing Test and the Dementia Rating Scale. Poster presented at the Annual Meeting of the International Neuropsychological Society, Toronto, Ontario, Canada. Grohman, K., Donnelly, K.Z., Kleiner, J.S., & Strang, J. (2002, February). Memory and olfactory discrimination in posttraumatic stress disorder. Poster presented at the Annual Meeting of the International Neuropsychological Society, Toronto, Ontario, Canada. Strang, J.S., Donnelly, K. Z., Grohman, K., & Kleiner, J.S. (2001, November). Attention and working memory in Gulf War Syndrome and depression. Poster presented at the Annual Meeting of the National Academy of Neuropsychology, San Francisco, California. Harlan, C., Allison, S., & Kleiner, J.S. (1998). On being “high and humble”: Impressions of individuals practicing tactical and genuine humility. Poster presented at Society of Southeastern Social Psychologists, Athens, GA.

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