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Search Results to Paul Prather

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Prather, Paul

One or more keywords matched the following items that are connected to Prather, Paul

Item Type	Name
Academic Article	A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors.
Academic Article	Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity.
Academic Article	Differential drug-drug interactions of the synthetic Cannabinoids JWH-018 and JWH-073: implications for drug abuse liability and pain therapy.
Academic Article	Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity.
Academic Article	Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds.
Academic Article	Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors.
Academic Article	Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine.
Academic Article	Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands.
Concept	Naphthalenes
Academic Article	The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products.
Academic Article	Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development.
Academic Article	Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants.
Academic Article	The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects.
Academic Article	Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein-Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with ?9-Tetrahydrocannabinol and JWH-018.
Academic Article	Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development.

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Naphthalenes