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Search Results to Paul Prather

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Prather, Paul

One or more keywords matched the following items that are connected to Prather, Paul

Item Type	Name
Academic Article	The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset.
Academic Article	Differential drug-drug interactions of the synthetic Cannabinoids JWH-018 and JWH-073: implications for drug abuse liability and pain therapy.
Academic Article	Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.
Academic Article	Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity.
Academic Article	Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds.
Academic Article	Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors.
Academic Article	Marijuana-based drugs: innovative therapeutics or designer drugs of abuse?
Academic Article	Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands.
Concept	Cannabinoids
Academic Article	Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to ?(9)-THC: mechanism underlying greater toxicity?
Academic Article	The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products.
Academic Article	The omega and omega-1 monohydroxyl metabolites of the abused K2/Spice synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as agonists at human cannabinoid 2 receptors (hCB2s)
Academic Article	Biotransformation of abused synthetic cannabinoids in K2/Spice by human hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs)
Academic Article	Tolerance and cross-tolerance among high-efficacy synthetic cannabinoids JWH-018 and JWH-073 and low-efficacy phytocannabinoid ?9-THC
Academic Article	Simultaneous Urinary Identification and Quantification and In Vitro Characterization of Omega and Omega-1 Metabolites of the abused synthetic cannabinoids JWH-018 and JWH-073
Academic Article	The K2/Spice phenomenon: The emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products
Academic Article	Cannabinoids and the Brain
Academic Article	Use of natural and synthetic cannabinoids to establish cannabinoid receptors as novel targets for the treatment of breast cancer
Academic Article	Preface to DMR special edition 'Cannabinoid receptors and ligands: therapeutic drug development and abuse potential'.
Grant	Selective CB2 Cannabinoid Agonists as Candidate Therapeutics for ALS
Academic Article	Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22).
Academic Article	Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein-Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with ?9-Tetrahydrocannabinol and JWH-018.
Academic Article	Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics.
Academic Article	Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development.
Academic Article	Metabolites of Synthetic Cannabinoid 5F-MDMB-PINACA Retain Affinity, Act as High Efficacy Agonists and Exhibit Atypical Pharmacodynamic Properties at CB1 Receptors.
Academic Article	Non-Canonical Cannabinoid Receptors with Distinct Binding and Signaling Properties in Prostate and Other Cancer Cell Types Mediate Cell Death.

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Cannabinoids