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Search Results to Piotr Zimniak

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Zimniak, Piotr

One or more keywords matched the following items that are connected to Zimniak, Piotr

Item Type	Name
Academic Article	Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells.
Academic Article	Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse.
Academic Article	Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal.
Academic Article	Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis.
Academic Article	Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells.
Academic Article	4-Hydroxynonenal and fat storage: A paradoxical pro-obesity mechanism?
Academic Article	4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas.
Academic Article	Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression.
Academic Article	Disruption of the mGsta4 gene increases life span of C57BL mice.
Academic Article	Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice.
Academic Article	Down-regulation of glutatione S-transferase a 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection.
Academic Article	Novel human ocular glutathione S-transferases with high activity toward 4-hydroxynonenal.
Academic Article	The human hGSTA5 gene encodes an enzymatically active protein.
Academic Article	Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE).
Academic Article	Mutagenic effects of 4-hydroxynonenal triacetate, a chemically protected form of the lipid peroxidation product 4-hydroxynonenal, as assayed in L5178Y/Tk+/- mouse lymphoma cells.
Academic Article	Relationship of electrophilic stress to aging.
Academic Article	Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of alpha, beta-unsaturated aldehydes.
Academic Article	Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues.
Academic Article	Amino acid residue 104 in an alpha-class glutathione S-transferase is essential for the high selectivity and specificity of the enzyme for 4-hydroxynonenal.
Academic Article	Catalytic function of Drosophila melanogaster glutathione S-transferase DmGSTS1-1 (GST-2) in conjugation of lipid peroxidation end products.
Academic Article	4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells.
Academic Article	Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal.
Academic Article	Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells.
Academic Article	Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells.
Academic Article	Transfection of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme, mouse GSTA4-4, confers doxorubicin resistance to Chinese hamster ovary cells.
Academic Article	Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface.
Academic Article	Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal.
Academic Article	The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (-/-) mice.
Academic Article	Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues.
Academic Article	Role of active-site residues 107 and 108 of glutathione S-transferase mGSTA4-4 in determining the catalytic properties of the enzyme for 4-hydroxynonenal.
Concept	Aldehydes
Academic Article	Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-a double knockout mice enhance injury during early stages of alcoholic liver disease.
Academic Article	Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice.
Grant	Role of glutathione transferases in life span extension of C. elegans
Grant	Role of Lipid peroxidation and 4-hydroxynonenal in aging

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Aldehydes