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One or more keywords matched the following properties of Byrum, Stephanie

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overview My research focus involves a translational approach for the identification of cancer systems biology, from the bench to the bedside. I have performed experiments ranging from collecting patient samples, to performing proteomic and genomic analyses, using bioinformatics to mine large complex data sets, and identify important clinical markers for metastatic breast cancer and melanoma. I have formal training in bioinformatics and mass spectrometry. My bioinformatics skill set includes: proteomics (label-free, stable isotope tags, SILAC, TMT-labeling, intensity-based analysis), epigenetics (quantitation of histone posttranslational modifications and chromatin remodelers), genomics (microarray, ChIP-seq, RNA-seq), metagenomics, biostatistics and data mining, and pathway and functional analysis. During my career I have consulted and provided bioinformatics analyses, including bench work, biostatistics, and OMICs data analyses, for 41 faculty on and off campus and mentored 20 students.

One or more keywords matched the following items that are connected to Byrum, Stephanie

Item TypeName
Academic Article ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus.
Academic Article Identification of PTHrP(12-48) as a plasma biomarker associated with breast cancer bone metastasis.
Academic Article A quantitative proteomic analysis of FFPE melanoma.
Academic Article Purification of a specific native genomic locus for proteomic analysis.
Concept Tandem Mass Spectrometry
Concept Mass Spectrometry
Academic Article A CRISPR-based approach for proteomic analysis of a single genomic locus.
Academic Article A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Academic Article Purification of specific chromatin loci for proteomic analysis.
Academic Article Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication.
Academic Article Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
Academic Article Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection.
Academic Article Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break.
Academic Article Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol.
Academic Article Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome.
Grant Development of technology for high resolution epigenetic profiling of chromatin
Grant Technology for Identification of Epiproteomes in Tissue Samples
Grant Identification of combinatorial histone post-translational modifications within t
Grant Identification of Druggable Targets to Complement Melanoma Therapy

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