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Search Results to Peter Crooks

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One or more keywords matched the following items that are connected to Crooks, Peter

Item TypeName
Concept Antibiotics, Antineoplastic
Concept Ethanol
Concept Amines
Concept Acetylcysteine
Concept Acetates
Concept Acetylcholinesterase
Concept Anti-Inflammatory Agents, Non-Steroidal
Concept Alkaloids
Concept Boronic Acids
Concept Analgesics, Opioid
Concept Antimetabolites, Antineoplastic
Concept Antiviral Agents
Concept Alkynes
Concept Anabasine
Concept Antineoplastic Agents
Concept Bacterial Proteins
Concept Benzyl Compounds
Concept Carboxy-Lyases
Concept Biphenyl Compounds
Concept Carboxylic Acids
Concept Alcohol Deterrents
Concept Cyclohexanols
Concept Choline
Concept Benzazepines
Concept Benzofurans
Concept Codeine
Concept Cisplatin
Concept Anti-Infective Agents
Concept Butyrylcholinesterase
Concept Deoxyglucose
Concept Aerosols
Concept Agmatine
Concept Anti-Bacterial Agents
Concept Dactinomycin
Concept Dihydroxyphenylalanine
Concept Drug Tolerance
Concept Drug Evaluation, Preclinical
Concept Dihydromorphine
Concept Estrenes
Concept Dextromethorphan
Concept Antineoplastic Agents, Phytogenic
Concept Antitubercular Agents
Concept Acetamides
Concept Acetonitriles
Concept Anticonvulsants
Concept Analgesics
Concept Angiotensin-Converting Enzyme Inhibitors
Concept Antifungal Agents
Concept Antioxidants
Concept Central Nervous System Stimulants
Concept Arginine
Concept Amino Acids
Concept Amphetamine
Concept Antihypertensive Agents
Concept Acrylonitrile
Concept Acetylcholine
Concept Aminobutyrates
Concept Aniline Compounds
Concept Arginine-tRNA Ligase
Concept Adhesives
Concept Antibodies, Monoclonal
Concept Aconitine
Concept Aminopyrine
Concept Quaternary Ammonium Compounds
Concept Anti-Inflammatory Agents
Concept Adrenergic beta-Antagonists
Concept Aldehydes
Concept Glass
Concept Glutathione Peroxidase
Concept Guanidines
Concept Octanols
Concept Azetidines
Concept Amides
Concept Immunotoxins
Concept Estradiol
Concept Benzylidene Compounds
Concept Benzopyrans
Concept Caproates
Concept Carbonates
Concept Formates
Concept Cations
Concept Boron
Concept Carbamates
Concept Fluorouracil
Concept Guaiacol
Concept Dopa Decarboxylase
Concept Drug Combinations
Concept Esters
Concept Aza Compounds
Concept Benzylamines
Concept Caffeine
Concept Dopamine
Concept Dose-Response Relationship, Drug
Concept DNA-Directed DNA Polymerase
Concept Drug Utilization
Concept Carrier Proteins
Concept Canavanine
Concept Chelating Agents
Concept Atenolol
Concept Benzene
Concept Binding Sites
Concept Butyrates
Concept Cannabinoids
Concept Gels
Concept Cholinesterase Inhibitors
Concept Colchicine
Concept Crystallization
Concept Cytoskeletal Proteins
Concept Delayed-Action Preparations
Concept Hydrazines
Concept Chromones
Concept Cocaine
Concept Base Sequence
Concept Cellulose, Oxidized
Concept Chlorobenzoates
Concept Isoquinolines
Concept Carcinogens
Concept Catalase
Concept Hydrogen
Concept Deoxyribonuclease I
Concept Dioxolanes
Concept Drug Resistance
Concept Pharmaceutical Preparations
Concept Ketamine
Concept Drug Carriers
Concept Enzyme Inhibitors
Concept Solvents
Concept Sulfhydryl Compounds
Concept Transcription Factors
Concept Dipeptides
Concept DNA-Binding Proteins
Concept Morphine
Concept Fluorescent Dyes
Concept Food
Concept Drugs, Investigational
Concept Formaldehyde
Concept Drug Synergism
Concept Prostaglandin-Endoperoxide Synthases
Concept Polyethylene Glycols
Concept Prodrugs
Concept Promoter Regions, Genetic
Concept Pyrimidines
Concept Reserpine
Concept Nomifensine
Concept Indolizines
Concept Quinoxalines
Concept Cytotoxins
Concept Membrane Proteins
Concept Stereoisomerism
Concept Streptozocin
Concept Sucrose
Concept Tablets
Concept Membrane Glycoproteins
Concept Sulfones
Concept Plant Extracts
Concept Oxygen
Concept Pregnanes
Concept Protein Disulfide Reductase (Glutathione)
Concept Sulfates
Concept Triazoles
Concept Growth Inhibitors
Concept Polyamines
Concept Tritium
Concept Vinyl Compounds
Concept 2,2'-Dipyridyl
Concept Drug Design
Concept Amyloid beta-Peptides
Concept Phenylurea Compounds
Concept Receptors, Cholinergic
Concept Sesquiterpenes
Concept Protein Subunits
Concept Indole Alkaloids
Concept Neurotransmitter Agents
Concept Muscarinic Antagonists
Concept Cytochrome P-450 CYP1A2
Concept Semicarbazones
Concept Urea
Concept Vincristine
Concept Receptors, N-Methyl-D-Aspartate
Concept Receptors, Opioid, kappa
Concept Dialysis Solutions
Concept Tryptophan
Concept Urethane
Concept Pregnanolone
Concept Proteins
Concept Superoxide Dismutase
Concept Barbiturates
Concept Calcium
Concept RNA, Small Interfering
Concept NADP
Concept Cholinergic Antagonists
Concept Phosphoserine
Concept Quinuclidines
Concept RNA
Concept Morphine Derivatives
Concept Nicotine
Concept Peptide Fragments
Concept Pyrazines
Concept Reference Standards
Concept GTP-Binding Proteins
Concept Timolol
Concept Valerates
Concept Guanidine
Concept Nicotinic Agonists
Concept Cyclooxygenase 2
Concept BRCA1 Protein
Concept Ubiquitin
Concept DNA-(Apurinic or Apyrimidinic Site) Lyase
Concept Recombinant Proteins
Concept Salts
Concept Mitogen-Activated Protein Kinase 9
Concept Tetradecanoylphorbol Acetate
Concept Neurotransmitter Uptake Inhibitors
Concept Cotinine
Concept Coumarins
Concept Granulocyte Colony-Stimulating Factor
Concept Proto-Oncogene Proteins p21(ras)
Concept Cyclin A
Concept Membrane Transport Modulators
Concept NF-kappa B p52 Subunit
Concept Vesicular Monoamine Transport Proteins
Concept Cyclooxygenase 2 Inhibitors
Concept Succinates
Concept Large Neutral Amino Acid-Transporter 1
Concept Neuroprotective Agents
Concept Tyrosine 3-Monooxygenase
Concept Mitochondrial Proteins
Concept RNA Helicases
Concept Drug Stability
Concept Hydrazones
Concept Glutathione
Concept Vesicular Biogenic Amine Transport Proteins
Concept Paraquat
Concept Propionates
Concept Rubidium
Concept Serotonin Plasma Membrane Transport Proteins
Concept Glutamate-Cysteine Ligase
Concept DNA
Concept Drug Interactions
Concept Formamides
Concept Melphalan
Concept NAD
Concept Narcotic Antagonists
Concept Nitrosamines
Concept Piperazines
Concept Tetrazoles
Concept NF-kappa B
Concept Angiogenesis Inhibitors
Concept Chitosan
Concept Neuropeptides
Concept Radiation-Protective Agents
Concept RNA, Messenger
Concept Vancomycin
Concept Durapatite
Concept Histones
Concept Sulindac
Concept Thiobarbiturates
Concept Tumor Suppressor Protein p53
Concept Dihydro-beta-Erythroidine
Concept Environmental Pollutants
Concept omega-N-Methylarginine
Concept Receptors, Opioid, delta
Concept Adrenergic Uptake Inhibitors
Concept Chemokines, C
Concept Taxoids
Concept BH3 Interacting Domain Death Agonist Protein
Concept Benzodioxoles
Concept Mecamylamine
Concept beta-Cyclodextrins
Concept PTEN Phosphohydrolase
Concept Rad51 Recombinase
Concept Benzothiazoles
Concept DNA Primers
Concept Serotonin Antagonists
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept bcl-X Protein
Concept Ethacrynic Acid
Concept Glucose
Concept Small Molecule Libraries
Concept Vitamin E
Concept Cannabinoid Receptor Agonists
Concept 3,4-Dihydroxyphenylacetic Acid
Concept Luminol
Concept Excitatory Amino Acid Antagonists
Concept Drug Delivery Systems
Concept Drug Therapy, Combination
Concept Excipients
Concept Dopamine Uptake Inhibitors
Concept Plasma Membrane Neurotransmitter Transport Proteins
Concept Deoxycytidine
Concept Blood Glucose
Concept Bungarotoxins
Concept Drug Discovery
Concept Drug Repositioning
Concept Antigens, CD34
Concept Drug Therapy
Concept Conotoxins
Concept Naltrexone
Concept Thiazoles
Concept Lactones
Concept Multienzyme Complexes
Concept Tromethamine
Concept Drug Inverse Agonism
Concept Tubulin Modulators
Concept Neurotransmitter Transport Proteins
Concept Fentanyl
Concept Endodeoxyribonucleases
Concept Nucleic Acid Synthesis Inhibitors
Concept Sirolimus
Concept Mutant Chimeric Proteins
Concept Nerve Tissue Proteins
Concept Ligands
Concept Iodine Radioisotopes
Concept Indoles
Concept Hydroquinones
Concept Imidazoles
Concept Heterocyclic Compounds
Concept Heterocyclic Compounds, 2-Ring
Concept Indomethacin
Concept Isoxazoles
Concept Hypoglycemic Agents
Concept Insecticides
Concept Drug-Seeking Behavior
Concept Lobeline
Concept Ganglionic Stimulants
Concept NADH, NADPH Oxidoreductases
Concept Norepinephrine
Concept Serotonin
Concept Sulfuric Acids
Concept Octanes
Concept Methamphetamine
Concept Naphthalenes
Concept Oligopeptides
Concept Thiophenes
Concept Norepinephrine Plasma Membrane Transport Proteins
Concept Psychotropic Drugs
Concept Pyridinium Compounds
Concept Stilbenes
Concept Teratogens
Concept Oxycodone
Concept Piperidines
Concept Pyrazoles
Concept Receptors, Nicotinic
Concept Pyridines
Concept Ki-67 Antigen
Concept Dinoprostone
Concept Viral Nonstructural Proteins
Concept Picolines
Concept Phosphatidylinositol 3-Kinases
Concept Nicotinic Antagonists
Concept Radiation-Sensitizing Agents
Concept Toxins, Biological
Concept Glucuronosyltransferase
Concept Water
Concept Tubulin
Concept Receptor, Cannabinoid, CB1
Concept Thiadiazoles
Concept Tetracycline
Concept Intracellular Signaling Peptides and Proteins
Concept Phosphoprotein Phosphatases
Concept Tosyl Compounds
Concept Anticarcinogenic Agents
Concept Sulfonamides
Concept Bupropion
Concept Cyclooxygenase Inhibitors
Concept Pyrrolidines
Concept Oxyquinoline
Concept Reactive Oxygen Species
Concept I-kappa B Proteins
Concept Tetrabenazine
Concept Thiazines
Concept Apoptosis
Concept Thioredoxins
Concept Cyclin D1
Concept Membrane Transport Proteins
Concept Tropanes
Concept Cholinergic Agonists
Concept Receptors, Opioid, mu
Concept Glucuronides
Concept Drug Resistance, Neoplasm
Concept Imidazolidines
Concept Dopamine Plasma Membrane Transport Proteins
Concept Myeloablative Agonists
Concept Molecular Chaperones
Concept Drug Partial Agonism
Concept bcl-2-Associated X Protein
Concept Ether-A-Go-Go Potassium Channels
Concept NF-E2-Related Factor 2
Concept Chromatin
Concept Dioxanes
Concept Drug Administration Schedule
Concept Drug Screening Assays, Antitumor
Concept Benzoquinones
Concept gamma-Cyclodextrins
Concept Caspase 3
Concept Neoplasm Proteins
Concept Norbornanes
Concept Proto-Oncogene Proteins c-bcl-2
Concept Receptor, Cannabinoid, CB2
Concept Oncogene Protein v-akt
Concept Forkhead Transcription Factors
Concept Cyclooctanes
Concept Transcription Factor RelA
Concept TOR Serine-Threonine Kinases
Concept Phosphates
Concept Hemicholinium 3
Concept Proto-Oncogene Proteins c-akt
Concept Mineral Oil
Concept Mucins
Concept Nuclear Proteins
Concept Progesterone
Concept Recombinant Fusion Proteins
Concept Rubidium Radioisotopes
Concept Cytokines
Concept Symporters
Concept Thiazolidines
Academic Article Heterocyclic aminoparthenolide derivatives modulate G(2)-M cell cycle progression during Xenopus oocyte maturation.
Academic Article Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Academic Article Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs.
Academic Article Novel cytoprotective inhibitors for apoptotic endonuclease G.
Academic Article Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4.
Academic Article Enhancement of transdermal delivery of 6-beta-naltrexol via a codrug linked to hydroxybupropion.
Academic Article Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD).
Academic Article L-Canavanine as a radiosensitization agent for human pancreatic cancer cells.
Academic Article An in vivo evaluation of the antiseizure activity and acute neurotoxicity of agmatine.
Academic Article A duplex "Gemini" prodrug of naltrexone for transdermal delivery.
Academic Article N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices.
Academic Article Bioconversion of naltrexone and its 3-O-alkyl-ester prodrugs in a human skin equivalent.
Academic Article Evaluation of O(3alpha)-, O(21)-di-(N(1)-methyloxycarbonyl-2, 4-dioxo-5-fluoropyrimidinyl) 17alpha-hydroxy-5beta-pregnan-20-one as a novel potential antiangiogenic codrug.
Academic Article An HPLC method for the simultaneous determination of neurotoxic dipyridyl isomers in human plasma.
Academic Article Effects of norketamine enantiomers in rodent models of persistent pain.
Academic Article The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins.
Academic Article Synthesis and antitubercular activity of a series of hydrazone and nitrovinyl analogs derived from heterocyclic aldehydes.
Academic Article Lobelane decreases methamphetamine self-administration in rats.
Academic Article Phase I and phase II ocular metabolic activities and the role of metabolism in ophthalmic prodrug and codrug design and delivery.
Academic Article Antileukemic activity of aminoparthenolide analogs.
Academic Article In vivo evaluation of 3-O-alkyl ester transdermal prodrugs of naltrexone in hairless guinea pigs.
Academic Article In vivo evaluation of a transdermal codrug of 6-beta-naltrexol linked to hydroxybupropion in hairless guinea pigs.
Academic Article Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence.
Academic Article The antiproliferative and immunotoxic effects of L-canavanine and L-canaline.
Academic Article Synthesis and hydrolytic behavior of two novel tripartate codrugs of naltrexone and 6beta-naltrexol with hydroxybupropion as potential alcohol abuse and smoking cessation agents.
Academic Article The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery.
Academic Article An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.
Academic Article Physicochemical evaluation, in vitro human skin diffusion, and concurrent biotransformation of 3-O-alkyl carbonate prodrugs of naltrexone.
Academic Article Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.
Academic Article Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature.
Academic Article Microwave assisted synthesis and in vitro cytotoxicities of substituted (Z)-2-amino-5-(1-benzyl-1H-indol-3-yl)methylene-1-methyl-1H-imidazol-4(5H)-ones against human tumor cell lines.
Academic Article Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter.
Academic Article Synthesis and in vitro evaluation of N-alkyl-3-hydroxy-3-(2-imino-3-methyl-5-oxoimidazolidin-4-yl)indolin-2-one analogs as potential anticancer agents.
Academic Article The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse.
Academic Article Nicotinic receptor antagonists as treatments for nicotine abuse.
Academic Article One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies.
Academic Article Synthesis and in vitro stability of amino acid prodrugs of 6-?-naltrexol for microneedle-enhanced transdermal delivery.
Academic Article Scopolamine sublingual spray: an alternative route of delivery for the treatment of motion sickness.
Academic Article Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture.
Academic Article The mechanism of L-canavanine cytotoxicity: arginyl tRNA synthetase as a novel target for anticancer drug discovery.
Academic Article The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens.
Academic Article In vitro permeation of a pegylated naltrexone prodrug across microneedle-treated skin.
Academic Article Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat.
Academic Article In vitro release studies on matrix type transdermal drug delivery systems of naltrexone and its acetyl prodrug.
Academic Article Transdermal delivery of bupropion and its active metabolite, hydroxybupropion: a prodrug strategy as an alternative approach.
Academic Article Effect of celecoxib and the novel anti-cancer agent, dimethylamino-parthenolide, in a developmental model of pancreatic cancer.
Academic Article Synthesis and evaluation of a series of homologues of lobelane at the vesicular monoamine transporter-2.
Academic Article Vesicular monoamine transporter 2: role as a novel target for drug development.
Academic Article A pharmacokinetic study on Z-(+/-)-2-(1-benzylindole-3-yl-methylene)azabicyclo[2.2.2]octane-3-ol; a novel radio-sensitization agent.
Academic Article Phenyl ring-substituted lobelane analogs: inhibition of [?H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article Aplysinopsin analogs: Synthesis and anti-proliferative activity of substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-diones.
Academic Article bPiDI: a novel selective a6?2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse.
Academic Article Inhibition of NF-?B and DNA double-strand break repair by DMAPT sensitizes non-small-cell lung cancers to X-rays.
Academic Article Human skin permeation of branched-chain 3-0-alkyl ester and carbonate prodrugs of naltrexone.
Academic Article Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release.
Academic Article N-n-alkylnicotinium analogs, a novel class of antagonists at alpha 4 beta 2* nicotinic acetylcholine receptors: inhibition of S(-)-nicotine-evoked 86Rb+ efflux from rat thalamic synaptosomes.
Academic Article Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation.
Academic Article Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse.
Academic Article Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.
Academic Article Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1).
Academic Article Nicotinic receptor-based therapeutics and candidates for smoking cessation.
Academic Article The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices.
Academic Article bis-Pyridinium cyclophanes: novel ligands with high affinity for the blood-brain barrier choline transporter.
Academic Article The effect of VMAT2 inhibitor GZ-793A on the reinstatement of methamphetamine-seeking in rats.
Academic Article Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Academic Article Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents.
Academic Article Antinociceptive effects and toxicity of morphine-6-O-sulfate sodium salt in rat models of pain.
Academic Article Oral administration of GZ-793A, a VMAT2 inhibitor, decreases methamphetamine self-administration in rats.
Academic Article Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release.
Academic Article The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens.
Academic Article The NF-kappaB inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib.
Academic Article The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.
Academic Article Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor Cells.
Academic Article Discovery of non-peptide, small molecule antagonists of a9a10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.
Academic Article Anti-cancer activity of carbamate derivatives of melampomagnolide B.
Academic Article Transdermal delivery of naltrexol and skin permeability lifetime after microneedle treatment in hairless guinea pigs.
Academic Article The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
Academic Article Dimethylamino parthenolide enhances the inhibitory effects of gemcitabine in human pancreatic cancer cells.
Academic Article 5-((1-Aroyl-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-diones as potential anticancer agents with anti-inflammatory properties.
Academic Article Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
Academic Article Synthesis and anti-proliferative activity of aromatic substituted 5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione analogs against human tumor cell lines.
Academic Article Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes.
Academic Article Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone.
Academic Article 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1).
Academic Article Effect of celecoxib and novel agent LC-1 in a hamster model of lung cancer.
Academic Article Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells.
Academic Article 1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.
Academic Article Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.
Academic Article N-[11CH3]Dimethylaminoparthenolide (DMAPT) uptake into orthotopic 9LSF glioblastoma tumors in the rat.
Academic Article Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.
Academic Article Identification of resveratrol analogs as potent anti-dengue agents using a cell-based assay.
Academic Article Identification of a melampomagnolide B analog as a potential lead molecule for treatment of acute myelogenous leukemia.
Academic Article Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells.
Academic Article Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors.
Academic Article Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats.
Academic Article Succinamide derivatives of melampomagnolide B and their anti-cancer activities.
Academic Article Stability studies of potent opioid analgesic, morphine-6-O-sulfate in various buffers and biological matrices by HPLC-DAD analysis.
Academic Article The analgesic and toxic effects of nornicotine enantiomers alone and in interaction with morphine in rodent models of acute and persistent pain.
Academic Article Interaction between morphine and norketamine enantiomers in rodent models of nociception.
Academic Article Bioavailability of ??-tetrahydrocannabinol following intranasal administration of a mucoadhesive gel spray delivery system in conscious rabbits.
Academic Article Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats.
Academic Article Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development.
Academic Article A novel chemical delivery system comprising an ocular sustained release formulation of a 3alpha, 17alpha, 21-trihydroxy-5beta-pregnan-20-one-BIS-5-fluorouracil [correction of flourouracil] codrug.
Academic Article Development of a GC-MS assay for the determination of fentanyl pharmacokinetics in rabbit plasma after sublingual spray delivery.
Academic Article Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents.
Academic Article Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats.
Academic Article Evaluation of morphine-like effects of the mixed mu/delta agonist morphine-6-O-sulfate in rats: Drug discrimination and physical dependence.
Academic Article MMB triazole analogs are potent NF-?B inhibitors and anti-cancer agents against both hematological and solid tumor cells.
Academic Article An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic a6?2* antagonist r-bPiDI.
Academic Article Actinomycin-D and dimethylamino-parthenolide synergism in treating human pancreatic cancer cells.
Academic Article A novel tetrazole analogue of resveratrol is a potent anticancer agent.
Academic Article N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3.
Grant Early Events in Alzheimer Pathogenesis
Academic Article Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein-Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with ?9-Tetrahydrocannabinol and JWH-018.
Grant Use of precision deuteration to determine the contribution of norbuprenorphine to buprenorphine-associated neonatal abstinence syndrome
Academic Article GZ-11608, a Vesicular Monoamine Transporter-2 Inhibitor, Decreases the Neurochemical and Behavioral Effects of Methamphetamine.
Academic Article Polyamine modulation of NMDARs as a mechanism to reduce effects of alcohol dependence.
Academic Article Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases.
Academic Article A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease.
Academic Article Deuteration of the farnesyl terminal methyl groups of d-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production.
Academic Article Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of A? Self-Aggregation and Metal Chelation-Induced A? Aggregation.
Academic Article 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands.
Academic Article A pharmacokinetic study of morphine-6-O-sulfate in rat plasma and brain.
Academic Article International care models for chronic kidney disease: methods and economics--United States.
Academic Article Tablet formulation studies on nimesulide and meloxicam-cyclodextrin binary systems.
Academic Article Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKK? ubiquitin-like domain (ULD).
Academic Article Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease.
Academic Article Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion.
Academic Article Selected Antihypertensive Agents and Their Fixed-Dose Combinations Effectively Ameliorate Trastuzumab-Mediated Cardiac Dysfunction In Rats.

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