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Search Results to Laura James

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overview Dr. James is the Director of the Translational Research Institute at the University of Arkansas for Medical Sciences. Her research interest is in translational studies of acetaminophen toxicity. She and her collaborators developed novel approaches for the quantitation of acetaminophen protein adducts in peripheral blood samples. She also directs clinical trials in children to develop safe and effective drug dosing strategies in a number of disease areas.

One or more keywords matched the following items that are connected to James, Laura

Item TypeName
Academic Article Correlation of MCP1 with toxicity in acetaminophen overdose.
Academic Article Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouse.
Academic Article Cytokines and toxicity in acetaminophen overdose.
Academic Article Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation.
Academic Article Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress.
Academic Article Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress.
Academic Article Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity.
Academic Article Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.
Academic Article Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression.
Academic Article Acetaminophen hepatotoxicity and HIF-1a induction in acetaminophen toxicity in mice occurs without hypoxia.
Academic Article Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure.
Academic Article Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity.
Academic Article Hair drug testing of children suspected of exposure to the manufacture of methamphetamine.
Academic Article K2 toxicity: fatal case of psychiatric complications following AM2201 exposure.
Academic Article Echinomycin decreases induction of vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity in mice.
Academic Article Effect of trifluoperazine on toxicity, HIF-1a induction and hepatocyte regeneration in acetaminophen toxicity in mice.
Academic Article Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity.
Academic Article Correlation of MRI findings to histology of acetaminophen toxicity in the mouse.
Concept Toxicity Tests
Concept Forensic Toxicology
Academic Article Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children.
Academic Article CYP1A2*1F allele predicts risk of liver toxicity in children prescribed acetaminophen following surgery
Academic Article Elevation of Cytokines in acetaminophen overdose
Academic Article Effects of trifluoperazine on toxicity, HIF-1 induction and hepatocyte regeneration in acetaminophen toxicity in mice
Academic Article Severe toxicity following synthetic cannabinoid ingestion
Academic Article Susceptibility to acetaminophen (APAP) toxicity unexpectedly is decreased during acute viral hepatitis in mice
Academic Article Mild hypothermia attenuates liver injury and improves survival in mice with acetaminophen toxicity
Academic Article Acetaminophen hepatotoxicity and HIF-1alpha induction in mice occurs without hypoxia
Academic Article Tumor Necrosis Factor Receptor 1 and Hepatocyte Regeneration in Acetaminophen Toxicity: A Kinetic Study of Proliferating Cell Nuclear Antigen and Cytoline Expression
Academic Article K@ toxicity: fatal case of psychiatric complications following AM2201 exposure
Academic Article Acylcarnitine profiles in acetaminophen toxicity in the mouse: comparison to toxicity, metabolism and hepatocyte regeneration
Academic Article Mechanisms of chloroform-induced hepatotoxicity: oxidative stess and mitochondrial permeability transition in freshly isolated mouse hepatocytes
Academic Article Indocyanin green clearance varies as a function of n-acetylcysteine treatment in a murine model of acetaminophen toxicity
Academic Article Examination of exogenous hrVEGF in a mouse model of acetaminophen toxicity
Academic Article Severe toxicity following synthetic cannabinoid ingestion
Academic Article Acylcarnitine profiles in acetaminophen toxicity in the mouse: comparison to toxicity, metabolism and hepatocyte regeneration.
Academic Article The role of intrahepatic CD3+/CD4-/CD8- double negative T (DN T) cells in enhanced acetaminophen toxicity.
Academic Article Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children.
Academic Article Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity.
Academic Article Translational biomarkers of acetaminophen-induced acute liver injury.
Academic Article The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes.
Academic Article Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes.
Academic Article MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity.
Academic Article Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose.
Academic Article Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration.
Academic Article The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3? and Wnt/?-catenin signaling.
Grant AcetaSTAT Rapid Assay for Acetaminophen Liver Injury
Grant NOVEL THERAPIES FOR ACETAMINOPHEN TOXICITY
Grant Identification of new mechanistic biomarkers of adverse responses to acetaminophe
Grant Synthetic Cannabinoid Toxicity: Role of Biotransformation
Grant Dipstick Assay for Detection of Acetaminophen Protein Adducts
Grant Evaluation of a Biomarker for Acetaminophen Toxicity
Grant HIF-1alpha and VEGF in Acetaminophen Toxicity and Repair
Grant Adduct Dipstick for Diagnosis of Acetaminophen Toxicity
Grant Synthetic Cannabinoid Toxicity: Role of Biotransformation
Academic Article Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children.
Academic Article Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice.
Academic Article Advances in biomarker development in acetaminophen toxicity.
Academic Article Acute Liver Failure of unclear cause? Acetaminophen-protein adducts make the diagnosis.
Academic Article Hands-Free Analytical Urine Testing Technology Validated for Drug-Facilitated Crime Investigations.

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