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Search Results to Stephanie Byrum

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One or more keywords matched the following properties of Byrum, Stephanie

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overview My research focus involves a translational approach for the identification of cancer systems biology, from the bench to the bedside. I have performed experiments ranging from collecting patient samples, to performing proteomic and genomic analyses, using bioinformatics to mine large complex data sets, and identify important clinical markers for metastatic breast cancer and melanoma. I have formal training in bioinformatics and mass spectrometry. My bioinformatics skill set includes: proteomics (label-free, stable isotope tags, SILAC, TMT-labeling, intensity-based analysis), epigenetics (quantitation of histone posttranslational modifications and chromatin remodelers), genomics (microarray, ChIP-seq, RNA-seq), metagenomics, biostatistics and data mining, and pathway and functional analysis. My research is currently focused on developing multi-omics data integration and proteogenomics applications.

One or more keywords matched the following items that are connected to Byrum, Stephanie

Item TypeName
Academic Article ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus.
Academic Article Purification of a specific native genomic locus for proteomic analysis.
Concept Peptide Chain Elongation, Translational
Concept Protein Processing, Post-Translational
Concept Computational Biology
Academic Article A CRISPR-based approach for proteomic analysis of a single genomic locus.
Academic Article A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Academic Article Purification of specific chromatin loci for proteomic analysis.
Academic Article Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
Academic Article Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break.
Grant Center for Translational Pediatric Research
Grant Defining the role of post-translational regulation by extracellular proteases in the pathogenesis of Staphylococcus aureus osteomyelitis
Grant Development of technology for high resolution epigenetic profiling of chromatin
Grant Identification of combinatorial histone post-translational modifications within t
Academic Article Continuous Developmental and Early Life Trichloroethylene Exposure Promoted DNA Methylation Alterations in Polycomb Protein Binding Sites in Effector/Memory CD4+ T Cells.
Academic Article Respiratory defects in the CrtapKO mouse model of osteogenesis imperfecta.
Academic Article ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data.
Academic Article PTMViz: a tool for analyzing and visualizing histone post translational modification data.

Search Criteria
  • Translational
  • Bioinformatics