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PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia.
Zhang J, Xiang Z, Malaviarachchi PA, Yan Y, Baltz NJ, Emanuel PD, Liu YL. PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia. Cell Signal. 2018 Oct; 50:72-79.
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PubMed
subject areas
Animals
Cell Line
Down-Regulation
Early Growth Response Protein 1
Granulocyte-Macrophage Colony-Stimulating Factor
HEK293 Cells
Humans
Leukemia, Myeloid
Mice
Mitogen-Activated Protein Kinases
Phosphorylation
Protein Kinase Inhibitors
Proto-Oncogene Proteins c-akt
PTEN Phosphohydrolase
Signal Transduction
authors with profiles
Nicholas Baltz