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Co-Authors

This is a "connection" page, showing publications co-authored by Srinivas Ayyadevara and Meenakshisundaram Balasubramaniam.

 
Connection Strength
  
 
 
3.430
  
  1. Ganne A, Mainali N, Balasubramaniam M, Atluri R, Pahal S, Asante J, Nagel C, Vallurupalli S, Shmookler Reis RJ, Ayyadevara S. Ezetimibe Lowers Risk of Alzheimer's and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction. Aging Biol. 2024; 2.
    View in: PubMed
    Score: 0.243
  2. Balasubramaniam M, Narasimhappagari J, Liu L, Ganne A, Ayyadevara S, Atluri R, Ayyadevara H, Caldwell G, Shmookler Reis RJ, Barger SW, Griffin WST. Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer's disease by targeted small molecules. Commun Biol. 2024 01 08; 7(1):60.
    View in: PubMed
    Score: 0.236
  3. Balasubramaniam M, Ganne A, Mainali N, Pahal S, Ayyadevara S, Shmookler Reis RJ. Alzheimer's-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets. iScience. 2024 Jan 19; 27(1):108745.
    View in: PubMed
    Score: 0.235
  4. Mainali N, Li X, Wang X, Balasubramaniam M, Ganne A, Kore R, Shmookler Reis RJ, Mehta JL, Ayyadevara S. Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain. Mol Cell Biochem. 2024 Oct; 479(10):2741-2753.
    View in: PubMed
    Score: 0.233
  5. Ganne A, Balasubramaniam M, Mainali N, Atluri P, Shmookler Reis RJ, Ayyadevara S. Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases. Int J Mol Sci. 2022 Dec 07; 23(24).
    View in: PubMed
    Score: 0.219
  6. Ganne A, Balasubramaniam M, Griffin WST, Shmookler Reis RJ, Ayyadevara S. Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease. Pharmaceutics. 2022 Jun 26; 14(7).
    View in: PubMed
    Score: 0.212
  7. Ayyadevara S, Ganne A, Balasubramaniam M, Shmookler Reis RJ. Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration. Metab Brain Dis. 2022 01; 37(1):147-152.
    View in: PubMed
    Score: 0.199
  8. Shmookler Reis RJ, Atluri R, Balasubramaniam M, Johnson J, Ganne A, Ayyadevara S. "Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation. Aging Cell. 2021 05; 20(5):e13326.
    View in: PubMed
    Score: 0.195
  9. Balasubramaniam M, Ayyadevara S, Ganne A, Kakraba S, Penthala NR, Du X, Crooks PA, Griffin ST, Shmookler Reis RJ. Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases. iScience. 2019 Oct 25; 20:248-264.
    View in: PubMed
    Score: 0.175
  10. Ayyadevara S, Ganne A, Hendrix RD, Balasubramaniam M, Shmookler Reis RJ, Barger SW. Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'. J Neurosci Methods. 2019 05 01; 319:40-46.
    View in: PubMed
    Score: 0.165
  11. Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ. Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2. Sci Rep. 2018 10 05; 8(1):14891.
    View in: PubMed
    Score: 0.164
  12. Balasubramaniam M, Shmookler Reis RJ, Ayyadevara S, Wang X, Ganne A, Khaidakov M. Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase. Mech Ageing Dev. 2017 09; 166:55-63.
    View in: PubMed
    Score: 0.151
  13. Ayyadevara S, Balasubramaniam M, Kakraba S, Alla R, Mehta JL, Shmookler Reis RJ. Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation. Antioxid Redox Signal. 2017 Dec 10; 27(17):1383-1396.
    View in: PubMed
    Score: 0.150
  14. Ayyadevara S, Balasubramaniam M, Suri P, Mackintosh SG, Tackett AJ, Sullivan DH, Shmookler Reis RJ, Dennis RA. Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans. Aging (Albany NY). 2016 12 15; 8(12):3486-3497.
    View in: PubMed
    Score: 0.144
  15. Ayyadevara S, Balasubramaniam M, Johnson J, Alla R, Mackintosh SG, Shmookler Reis RJ. PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans. Oncotarget. 2016 Aug 02; 7(31):48870-48886.
    View in: PubMed
    Score: 0.141
  16. Ayyadevara S, Balasubramaniam M, Parcon PA, Barger SW, Griffin WS, Alla R, Tackett AJ, Mackintosh SG, Petricoin E, Zhou W, Shmookler Reis RJ. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell. 2016 10; 15(5):924-39.
    View in: PubMed
    Score: 0.141
  17. Ayyadevara S, Balasubramaniam M, Gao Y, Yu LR, Alla R, Shmookler Reis R. Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes. Aging Cell. 2015 Feb; 14(1):35-48.
    View in: PubMed
    Score: 0.126
  18. Mainali N, Balasubramaniam M, Johnson J, Ayyadevara S, Shmookler Reis RJ. Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data. Bioinformation. 2024; 20(1):4-10.
    View in: PubMed
    Score: 0.059
  19. Kakraba S, Ayyadevara S, Mainali N, Balasubramaniam M, Bowroju S, Penthala NR, Atluri R, Barger SW, Griffin ST, Crooks PA, Shmookler Reis RJ. Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan. Pharmaceuticals (Basel). 2023 Oct 20; 16(10).
    View in: PubMed
    Score: 0.058
  20. Ganne A, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ. Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation. Front Aging Neurosci. 2022; 14:938117.
    View in: PubMed
    Score: 0.053
  21. Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. Bioorg Med Chem. 2021 09 01; 45:116311.
    View in: PubMed
    Score: 0.050
  22. Kakraba S, Ayyadevara S, Penthala NR, Balasubramaniam M, Ganne A, Liu L, Alla R, Bommagani SB, Barger SW, Griffin WST, Crooks PA, Shmookler Reis RJ. A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease. Front Mol Neurosci. 2019; 12:310.
    View in: PubMed
    Score: 0.044
  23. Parcon PA, Balasubramaniam M, Ayyadevara S, Jones RA, Liu L, Shmookler Reis RJ, Barger SW, Mrak RE, Griffin WST. Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs. Alzheimers Dement. 2018 02; 14(2):230-242.
    View in: PubMed
    Score: 0.038
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.