Multicellular tumor-stromal interactions recapitulate aspects of therapeutic response and human oncogenic signaling in a 3D disease model for H3K27M-altered DIPG.
Upreti M, Petrosyan A, Thornton ME, Hovsepyan A, Fernandez GE, Koos DS, Byrum SD, Mackintosh SG, Al-Husseini JK, Porras T, Ha J, Tackett AJ, Zhang M, Johal MS, Erdreich-Epstein A, Durham S, Krieger MD, Margol AS, Grubbs BH, Chambers TC, Asgharzadeh S, Moats RA, Chiarelli PA. Multicellular tumor-stromal interactions recapitulate aspects of therapeutic response and human oncogenic signaling in a 3D disease model for H3K27M-altered DIPG. Oncogene. 2025 Oct; 44(39):3694-3712.