QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum.

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QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum.

Zheng F, McConnell MJ, Zhan CG, Dwoskin LP, Crooks PA. QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum. Bioorg Med Chem. 2009 Jul 01; 17(13):4477-85.

View in: PubMed

subject areas

Animals
Corpus Striatum
Dopamine
Linear Models
Models, Biological
Molecular Structure
Nicotine
Nicotinic Antagonists
Quantitative Structure-Activity Relationship
Quaternary Ammonium Compounds
Rats
Receptors, Nicotinic

authors with profiles

Peter Crooks