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Connection

Peter Crooks to Prodrugs

This is a "connection" page, showing publications Peter Crooks has written about Prodrugs.

 
Connection Strength
  
 
 
2.644
  
  1. Eldridge JA, Milewski M, Stinchcomb AL, Crooks PA. Synthesis and in vitro stability of amino acid prodrugs of 6-?-naltrexol for microneedle-enhanced transdermal delivery. Bioorg Med Chem Lett. 2014 Nov 15; 24(22):5212-5.
    View in: PubMed
    Score: 0.502
  2. Yerramreddy TR, Milewski M, Penthala NR, Stinchcomb AL, Crooks PA. Novel 3-O-pegylated carboxylate and 3-O-pegylated carbamate prodrugs of naltrexone for microneedle-enhanced transdermal delivery. Bioorg Med Chem Lett. 2010 Jun 01; 20(11):3280-3.
    View in: PubMed
    Score: 0.368
  3. Al-Ghananeem AM, Crooks PA. Phase I and phase II ocular metabolic activities and the role of metabolism in ophthalmic prodrug and codrug design and delivery. Molecules. 2007 Mar 08; 12(3):373-88.
    View in: PubMed
    Score: 0.297
  4. Chandrasekaran S, Al-Ghananeem AM, Riggs RM, Crooks PA. Synthesis and stability of two indomethacin prodrugs. Bioorg Med Chem Lett. 2006 Apr 01; 16(7):1874-9.
    View in: PubMed
    Score: 0.275
  5. Cynkowska G, Cynkowski T, Al-Ghananeem AM, Al-Ghananeem AA, Guo H, Ashton P, Crooks PA. Novel antiglaucoma prodrugs and codrugs of ethacrynic acid. Bioorg Med Chem Lett. 2005 Aug 01; 15(15):3524-7.
    View in: PubMed
    Score: 0.266
  6. Milewski M, Yerramreddy TR, Ghosh P, Crooks PA, Stinchcomb AL. In vitro permeation of a pegylated naltrexone prodrug across microneedle-treated skin. J Control Release. 2010 Aug 17; 146(1):37-44.
    View in: PubMed
    Score: 0.093
  7. Vaddi HK, Banks SL, Chen J, Hammell DC, Crooks PA, Stinchcomb AL. Human skin permeation of 3-O-alkyl carbamate prodrugs of naltrexone. J Pharm Sci. 2009 Aug; 98(8):2611-25.
    View in: PubMed
    Score: 0.088
  8. Kiptoo PK, Paudel KS, Hammell DC, Pinninti RR, Chen J, Crooks PA, Stinchcomb AL. Transdermal delivery of bupropion and its active metabolite, hydroxybupropion: a prodrug strategy as an alternative approach. J Pharm Sci. 2009 Feb; 98(2):583-94.
    View in: PubMed
    Score: 0.085
  9. Kiptoo PK, Paudel KS, Hammell DC, Hamad MO, Crooks PA, Stinchcomb AL. In vivo evaluation of a transdermal codrug of 6-beta-naltrexol linked to hydroxybupropion in hairless guinea pigs. Eur J Pharm Sci. 2008 Apr 23; 33(4-5):371-9.
    View in: PubMed
    Score: 0.079
  10. Howard-Sparks M, Al-Ghananeem AM, Crooks PA, Pearson AP. A novel chemical delivery system comprising an ocular sustained release formulation of a 3alpha, 17alpha, 21-trihydroxy-5beta-pregnan-20-one-BIS-5-fluorouracil [correction of flourouracil] codrug. Drug Dev Ind Pharm. 2007 Jun; 33(6):677-82.
    View in: PubMed
    Score: 0.075
  11. Nalluri BN, Milligan C, Chen J, Crooks PA, Stinchcomb AL. In vitro release studies on matrix type transdermal drug delivery systems of naltrexone and its acetyl prodrug. Drug Dev Ind Pharm. 2005 Oct; 31(9):871-7.
    View in: PubMed
    Score: 0.067
  12. Paudel KS, Nalluri BN, Hammell DC, Valiveti S, Kiptoo P, Hamad MO, Crooks PA, Stinchcomb AL. Transdermal delivery of naltrexone and its active metabolite 6-beta-naltrexol in human skin in vitro and guinea pigs in vivo. J Pharm Sci. 2005 Sep; 94(9):1965-75.
    View in: PubMed
    Score: 0.067
  13. Valiveti S, Paudel KS, Hammell DC, Hamad MO, Chen J, Crooks PA, Stinchcomb AL. In vitro/in vivo correlation of transdermal naltrexone prodrugs in hairless guinea pigs. Pharm Res. 2005 Jun; 22(6):981-9.
    View in: PubMed
    Score: 0.066
  14. Vaddi HK, Hamad MO, Chen J, Banks SL, Crooks PA, Stinchcomb AL. Human skin permeation of branched-chain 3-0-alkyl ester and carbonate prodrugs of naltrexone. Pharm Res. 2005 May; 22(5):758-65.
    View in: PubMed
    Score: 0.065
  15. Hammell DC, Stolarczyk EI, Klausner M, Hamad MO, Crooks PA, Stinchcomb AL. Bioconversion of naltrexone and its 3-O-alkyl-ester prodrugs in a human skin equivalent. J Pharm Sci. 2005 Apr; 94(4):828-36.
    View in: PubMed
    Score: 0.065
  16. Valiveti S, Hammell DC, Paudel KS, Hamad MO, Crooks PA, Stinchcomb AL. In vivo evaluation of 3-O-alkyl ester transdermal prodrugs of naltrexone in hairless guinea pigs. J Control Release. 2005 Feb 02; 102(2):509-20.
    View in: PubMed
    Score: 0.064
  17. Pillai O, Hamad MO, Crooks PA, Stinchcomb AL. Physicochemical evaluation, in vitro human skin diffusion, and concurrent biotransformation of 3-O-alkyl carbonate prodrugs of naltrexone. Pharm Res. 2004 Jul; 21(7):1146-52.
    View in: PubMed
    Score: 0.062
  18. Hammell DC, Hamad M, Vaddi HK, Crooks PA, Stinchcomb AL. A duplex "Gemini" prodrug of naltrexone for transdermal delivery. J Control Release. 2004 Jun 18; 97(2):283-90.
    View in: PubMed
    Score: 0.061
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.