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Identification of hydroxywarfarin binding site in human UGT1A10: Phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxy- but not 8-hydroxywarfarin

Miller, GP, Lichti, CF, Zielinska, AK, Bratton, SM, Mazur, A, Gallus-Zawada, A, Finel, M, Moran, JH, Radominska-Pandya, A. Identification of hydroxywarfarin binding site in human UGT1A10: Phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxy- but not 8-hydroxywarfarin. Drug Metab Dispo. 2008; 36:2211-8.


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