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Connection

Jawahar Mehta to Scavenger Receptors, Class E

This is a "connection" page, showing publications Jawahar Mehta has written about Scavenger Receptors, Class E.

 
Connection Strength
 
 
 
16.882
 
  1. Kore RA, Bagchi AK, Varughese KI, Mehta JL. The structural basis of effective LOX-1 inhibition. Future Med Chem. 2022 05; 14(10):731-743.
    View in: PubMed
    Score: 0.694
  2. Kore RA, Henson JC, Hamzah RN, Griffin RJ, Tackett AJ, Ding Z, Mehta JL. Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes. Sci Rep. 2019 12 17; 9(1):19276.
    View in: PubMed
    Score: 0.589
  3. Ding Z, Liu S, Wang X, Theus S, Deng X, Fan Y, Zhou S, Mehta JL. PCSK9 regulates expression of scavenger receptors and ox-LDL uptake in macrophages. Cardiovasc Res. 2018 07 01; 114(8):1145-1153.
    View in: PubMed
    Score: 0.532
  4. Dai Y, Wu X, Dai D, Li J, Mehta JL. MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1. Redox Biol. 2018 06; 16:255-262.
    View in: PubMed
    Score: 0.521
  5. Pothineni NVK, Karathanasis SK, Ding Z, Arulandu A, Varughese KI, Mehta JL. LOX-1 in Atherosclerosis and Myocardial?Ischemia: Biology, Genetics, and Modulation. J Am Coll Cardiol. 2017 Jun 06; 69(22):2759-2768.
    View in: PubMed
    Score: 0.495
  6. Dai Y, Cao Y, Zhang Z, Vallurupalli S, Mehta JL. Xanthine Oxidase Induces Foam Cell Formation through LOX-1 and NLRP3 Activation. Cardiovasc Drugs Ther. 2017 Feb; 31(1):19-27.
    View in: PubMed
    Score: 0.483
  7. Wang X, Ding Z, Lin J, Guo Z, Mehta JL. LOX-1 in macrophage migration in response to ox-LDL and the involvement of calpains. Biochem Biophys Res Commun. 2015 Nov 06; 467(1):135-9.
    View in: PubMed
    Score: 0.439
  8. Ding Z, Liu S, Wang X, Deng X, Fan Y, Shahanawaz J, Shmookler Reis RJ, Varughese KI, Sawamura T, Mehta JL. Cross-talk between LOX-1 and PCSK9 in vascular tissues. Cardiovasc Res. 2015 Sep 01; 107(4):556-67.
    View in: PubMed
    Score: 0.432
  9. Ding Z, Liu S, Wang X, Khaidakov M, Fan Y, Deng X, Xiang D, Mehta JL. Lectin-like oxidized low-density lipoprotein receptor-1 regulates autophagy and Toll-like receptor 4 in the brain of hypertensive mice. J Hypertens. 2015 Mar; 33(3):525-33; discussion 533.
    View in: PubMed
    Score: 0.423
  10. Ding Z, Liu S, Deng X, Fan Y, Wang X, Mehta JL. Hemodynamic shear stress modulates endothelial cell autophagy: Role of LOX-1. Int J Cardiol. 2015 Apr 01; 184:86-95.
    View in: PubMed
    Score: 0.420
  11. Wang X, Khaidakov M, Guo Z, Ding Z, He Q, Mehta JL. LOX-1 deletion limits cardiac angiogenesis in mice given angiotensin II. Cardiovasc Drugs Ther. 2014 Oct; 28(5):441-6.
    View in: PubMed
    Score: 0.411
  12. Ding Z, Liu S, Wang X, Theus S, Fan Y, Deng X, Mehta JL. LOX-1 - dependent mitochondrial DNA damage and NLRP3 activation during systemic inflammation in mice. Biochem Biophys Res Commun. 2014 Sep 05; 451(4):637-43.
    View in: PubMed
    Score: 0.407
  13. Ding Z, Liu S, Wang X, Khaidakov M, Dai Y, Deng X, Fan Y, Xiang D, Mehta JL. Lectin-like ox-LDL receptor-1 (LOX-1)-Toll-like receptor 4 (TLR4) interaction and autophagy in CATH.a differentiated cells exposed to angiotensin II. Mol Neurobiol. 2015 Apr; 51(2):623-32.
    View in: PubMed
    Score: 0.402
  14. Ding Z, Liu S, Wang X, Dai Y, Khaidakov M, Deng X, Fan Y, Xiang D, Mehta JL. LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis. Cardiovasc Res. 2014 Sep 01; 103(4):619-28.
    View in: PubMed
    Score: 0.399
  15. Ding Z, Liu S, Wang X, Dai Y, Khaidakov M, Romeo F, Mehta JL. LOX-1, oxidant stress, mtDNA damage, autophagy, and immune response in atherosclerosis. Can J Physiol Pharmacol. 2014 Jul; 92(7):524-30.
    View in: PubMed
    Score: 0.393
  16. Ding Z, Mizeracki AM, Hu C, Mehta JL. LOX-1 deletion and macrophage trafficking in atherosclerosis. Biochem Biophys Res Commun. 2013 Oct 18; 440(2):210-4.
    View in: PubMed
    Score: 0.382
  17. Dai Y, Mercanti F, Dai D, Wang X, Ding Z, Pothineni NV, Mehta JL. LOX-1, a bridge between GLP-1R and mitochondrial ROS generation in human vascular smooth muscle cells. Biochem Biophys Res Commun. 2013 Jul 19; 437(1):62-6.
    View in: PubMed
    Score: 0.376
  18. Ding Z, Liu S, Sun C, Chen Z, Fan Y, Deng X, Wang X, Mehta JL. Concentration polarization of ox-LDL activates autophagy and apoptosis via regulating LOX-1 expression. Sci Rep. 2013; 3:2091.
    View in: PubMed
    Score: 0.364
  19. Wang X, Khaidakov M, Ding Z, Mitra S, Lu J, Dai Y, Mehta JL. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and cardiac fibroblast growth. Hypertension. 2012 Dec; 60(6):1437-42.
    View in: PubMed
    Score: 0.358
  20. Lu J, Wang X, Wang W, Muniyappa H, Deshmukh A, Hu C, Das K, Mehta JL. Abrogation of lectin-like oxidized LDL receptor-1 attenuates acute myocardial ischemia-induced renal dysfunction by modulating systemic and local inflammation. Kidney Int. 2012 Aug; 82(4):436-44.
    View in: PubMed
    Score: 0.353
  21. Hermonat PL, Zhu H, Cao M, Mehta JL. LOX-1 transcription. Cardiovasc Drugs Ther. 2011 Oct; 25(5):393-400.
    View in: PubMed
    Score: 0.334
  22. Mehta JL, Khaidakov M, Hermonat PL, Mitra S, Wang X, Novelli G, Sawamura T. LOX-1: a new target for therapy for cardiovascular diseases. Cardiovasc Drugs Ther. 2011 Oct; 25(5):495-500.
    View in: PubMed
    Score: 0.334
  23. L? J, Mehta JL. LOX-1: a critical player in the genesis and progression of myocardial ischemia. Cardiovasc Drugs Ther. 2011 Oct; 25(5):431-40.
    View in: PubMed
    Score: 0.334
  24. Khaidakov M, Mehta JL. Do atherosclerosis and obesity-associated susceptibility to cancer share causative link to oxLDL and LOX-1? Cardiovasc Drugs Ther. 2011 Oct; 25(5):477-87.
    View in: PubMed
    Score: 0.334
  25. Khaidakov M, Wang X, Mehta JL. Potential involvement of LOX-1 in functional consequences of endothelial senescence. PLoS One. 2011; 6(6):e20964.
    View in: PubMed
    Score: 0.327
  26. Khaidakov M, Szwedo J, Mitra S, Ayyadevara S, Dobretsov M, Lu J, Mehta JL. Antiangiogenic and antimitotic effects of aspirin in hypoxia?reoxygenation modulation of the LOX-1-NADPH oxidase axis as a potential mechanism. J Cardiovasc Pharmacol. 2010 Dec; 56(6):635-41.
    View in: PubMed
    Score: 0.315
  27. Kang BY, Khan JA, Ryu S, Shekhar R, Seung KB, Mehta JL. Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition. J Cardiovasc Pharmacol. 2010 Apr; 55(4):417-24.
    View in: PubMed
    Score: 0.301
  28. Kang BY, Hu C, Ryu S, Khan JA, Biancolella M, Prayaga S, Seung KB, Novelli G, Mehta P, Mehta JL. Genomics of cardiac remodeling in angiotensin II-treated wild-type and LOX-1-deficient mice. Physiol Genomics. 2010 Jun; 42(1):42-54.
    View in: PubMed
    Score: 0.300
  29. Kang BY, Khan JA, Ryu S, Shekhar R, Seung KB, Mehta JL. Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition. J Cardiovasc Pharmacol. 2010 Feb; 55(2):176-83.
    View in: PubMed
    Score: 0.297
  30. Kang BY, Mehta JL. Rosuvastatin attenuates Ang II--mediated cardiomyocyte hypertrophy via inhibition of LOX-1. J Cardiovasc Pharmacol Ther. 2009 Dec; 14(4):283-91.
    View in: PubMed
    Score: 0.289
  31. Hu C, Kang BY, Megyesi J, Kaushal GP, Safirstein RL, Mehta JL. Deletion of LOX-1 attenuates renal injury following angiotensin II infusion. Kidney Int. 2009 Sep; 76(5):521-7.
    View in: PubMed
    Score: 0.285
  32. Li D, Mehta JL. Intracellular signaling of LOX-1 in endothelial cell apoptosis. Circ Res. 2009 Mar 13; 104(5):566-8.
    View in: PubMed
    Score: 0.279
  33. Hu C, Dandapat A, Sun L, Chen J, Marwali MR, Romeo F, Sawamura T, Mehta JL. LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet. Cardiovasc Res. 2008 Jul 15; 79(2):287-93.
    View in: PubMed
    Score: 0.263
  34. Hu C, Dandapat A, Sun L, Khan JA, Liu Y, Hermonat PL, Mehta JL. Regulation of TGFbeta1-mediated collagen formation by LOX-1: studies based on forced overexpression of TGFbeta1 in wild-type and lox-1 knock-out mouse cardiac fibroblasts. J Biol Chem. 2008 Apr 18; 283(16):10226-31.
    View in: PubMed
    Score: 0.258
  35. Hu C, Chen J, Dandapat A, Fujita Y, Inoue N, Kawase Y, Jishage K, Suzuki H, Li D, Hermonat PL, Sawamura T, Mehta JL. LOX-1 abrogation reduces myocardial ischemia-reperfusion injury in mice. J Mol Cell Cardiol. 2008 Jan; 44(1):76-83.
    View in: PubMed
    Score: 0.254
  36. Dandapat A, Hu C, Sun L, Mehta JL. Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway. Arterioscler Thromb Vasc Biol. 2007 Nov; 27(11):2435-42.
    View in: PubMed
    Score: 0.251
  37. Hu C, Dandapat A, Chen J, Fujita Y, Inoue N, Kawase Y, Jishage K, Suzuki H, Sawamura T, Mehta JL. LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfusion. Cardiovasc Res. 2007 Nov 01; 76(2):292-302.
    View in: PubMed
    Score: 0.249
  38. Marwali MR, Hu CP, Mohandas B, Dandapat A, Deonikar P, Chen J, Cawich I, Sawamura T, Kavdia M, Mehta JL. Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling. J Pharmacol Exp Ther. 2007 Sep; 322(3):1324-32.
    View in: PubMed
    Score: 0.247
  39. Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L, Beger R, Hermonat PL, Thomas M, Sawamura T. Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res. 2007 Jun 08; 100(11):1634-42.
    View in: PubMed
    Score: 0.246
  40. Novelli G, Borgiani P, Mango R, Romeo F, Mehta JL. OLR1 gene and coronary artery disease/acute myocardial infarction: replication in an independently collected sample. Eur J Hum Genet. 2006 Aug; 14(8):894-5; author reply 895.
    View in: PubMed
    Score: 0.230
  41. Chen J, Liu Y, Liu H, Hermonat PL, Mehta JL. Molecular dissection of angiotensin II-activated human LOX-1 promoter. Arterioscler Thromb Vasc Biol. 2006 May; 26(5):1163-8.
    View in: PubMed
    Score: 0.226
  42. Chen J, Liu Y, Liu H, Hermonat PL, Mehta JL. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) transcriptional regulation by Oct-1 in human endothelial cells: implications for atherosclerosis. Biochem J. 2006 Jan 01; 393(Pt 1):255-65.
    View in: PubMed
    Score: 0.224
  43. Chen K, Chen J, Liu Y, Xie J, Li D, Sawamura T, Hermonat PL, Mehta JL. Adhesion molecule expression in fibroblasts: alteration in fibroblast biology after transfection with LOX-1 plasmids. Hypertension. 2005 Sep; 46(3):622-7.
    View in: PubMed
    Score: 0.218
  44. Chen J, Li D, Schaefer R, Mehta JL. Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan. Atherosclerosis. 2006 Feb; 184(2):295-301.
    View in: PubMed
    Score: 0.216
  45. Dai Y, Zhang Z, Cao Y, Mehta JL, Li J. MiR-590-5p Inhibits Oxidized- LDL Induced Angiogenesis by Targeting LOX-1. Sci Rep. 2016 Mar 02; 6:22607.
    View in: PubMed
    Score: 0.113
  46. Thakkar S, Wang X, Khaidakov M, Dai Y, Gokulan K, Mehta JL, Varughese KI. Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein. Sci Rep. 2015 Nov 18; 5:16740.
    View in: PubMed
    Score: 0.111
  47. Ding Z, Liu S, Wang X, Deng X, Fan Y, Sun C, Wang Y, Mehta JL. Hemodynamic shear stress via ROS modulates PCSK9 expression in human vascular endothelial and smooth muscle cells and along the mouse aorta. Antioxid Redox Signal. 2015 Mar 20; 22(9):760-71.
    View in: PubMed
    Score: 0.105
  48. Ding Z, Liu S, Wang X, Khaidakov M, Dai Y, Mehta JL. Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis. Sci Rep. 2013; 3:1077.
    View in: PubMed
    Score: 0.091
  49. Ding Z, Wang X, Khaidakov M, Liu S, Dai Y, Mehta JL. Degradation of heparan sulfate proteoglycans enhances oxidized-LDL-mediated autophagy and apoptosis in human endothelial cells. Biochem Biophys Res Commun. 2012 Sep 14; 426(1):106-11.
    View in: PubMed
    Score: 0.089
  50. Vecchione L, Diano L, Campagnolo L, Rocchi L, Ferr? F, Mehta JL, Novelli G, Amati F. Functional characterization and expression analysis of novel alternative splicing isoforms of Olr1 gene during mouse embryogenesis. Gene. 2012 Jan 01; 491(1):5-12.
    View in: PubMed
    Score: 0.083
  51. Luo P, Yan M, Frohlich ED, Mehta JL, Hu C. Novel concepts in the genesis of hypertension: role of LOX-1. Cardiovasc Drugs Ther. 2011 Oct; 25(5):441-9.
    View in: PubMed
    Score: 0.083
  52. Yan M, Mehta JL, Zhang W, Hu C. LOX-1, oxidative stress and inflammation: a novel mechanism for diabetic cardiovascular complications. Cardiovasc Drugs Ther. 2011 Oct; 25(5):451-9.
    View in: PubMed
    Score: 0.083
  53. Mitra S, Deshmukh A, Sachdeva R, Lu J, Mehta JL. Oxidized low-density lipoprotein and atherosclerosis implications in antioxidant therapy. Am J Med Sci. 2011 Aug; 342(2):135-42.
    View in: PubMed
    Score: 0.082
  54. Mitra S, Khaidakov M, Lu J, Ayyadevara S, Szwedo J, Wang XW, Chen C, Khaidakov S, Kasula SR, Stone A, Pogribny I, Mehta JL. Prior exposure to oxidized low-density lipoprotein limits apoptosis in subsequent generations of endothelial cells by altering promoter methylation. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H506-13.
    View in: PubMed
    Score: 0.081
  55. Dominguez JH, Mehta JL, Li D, Wu P, Kelly KJ, Packer CS, Temm C, Goss E, Cheng L, Zhang S, Patterson CE, Hawes JW, Peterson R. Anti-LOX-1 therapy in rats with diabetes and dyslipidemia: ablation of renal vascular and epithelial manifestations. Am J Physiol Renal Physiol. 2008 Jan; 294(1):F110-9.
    View in: PubMed
    Score: 0.064
  56. Hu CP, Dandapat A, Liu Y, Hermonat PL, Mehta JL. Blockade of hypoxia-reoxygenation-mediated collagen type I expression and MMP activity by overexpression of TGF-beta1 delivered by AAV in mouse cardiomyocytes. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1833-8.
    View in: PubMed
    Score: 0.062
  57. Mehta JL. The role of LOX-1, a novel lectin-like receptor for oxidized low density lipoprotein, in atherosclerosis. Can J Cardiol. 2004 Aug; 20 Suppl B:32B-36B.
    View in: PubMed
    Score: 0.051
  58. Khan MA, Mohammad I, Banerjee S, Tomar A, Varughese KI, Mehta JL, Chandele A, Arockiasamy A. Oxidized LDL receptors: a recent update. Curr Opin Lipidol. 2023 08 01; 34(4):147-155.
    View in: PubMed
    Score: 0.047
  59. Li D, Williams V, Liu L, Chen H, Sawamura T, Romeo F, Mehta JL. Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia-reperfusion and its role in determination of apoptosis and left ventricular dysfunction. J Am Coll Cardiol. 2003 Mar 19; 41(6):1048-55.
    View in: PubMed
    Score: 0.046
  60. Li D, Liu L, Chen H, Sawamura T, Ranganathan S, Mehta JL. LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation. 2003 Feb 04; 107(4):612-7.
    View in: PubMed
    Score: 0.046
  61. Li D, Chen H, Romeo F, Sawamura T, Saldeen T, Mehta JL. Statins modulate oxidized low-density lipoprotein-mediated adhesion molecule expression in human coronary artery endothelial cells: role of LOX-1. J Pharmacol Exp Ther. 2002 Aug; 302(2):601-5.
    View in: PubMed
    Score: 0.044
  62. Mehta JL, Li DY, Chen HJ, Joseph J, Romeo F. Inhibition of LOX-1 by statins may relate to upregulation of eNOS. Biochem Biophys Res Commun. 2001 Dec 14; 289(4):857-61.
    View in: PubMed
    Score: 0.042
  63. Liu ML, Scalia R, Mehta JL, Williams KJ. Cholesterol-induced membrane microvesicles as novel carriers of damage-associated molecular patterns: mechanisms of formation, action, and detoxification. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2113-21.
    View in: PubMed
    Score: 0.022
  64. Rasouli N, Yao-Borengasser A, Varma V, Spencer HJ, McGehee RE, Peterson CA, Mehta JL, Kern PA. Association of scavenger receptors in adipose tissue with insulin resistance in nondiabetic humans. Arterioscler Thromb Vasc Biol. 2009 Sep; 29(9):1328-35.
    View in: PubMed
    Score: 0.018
  65. Mango R, Biocca S, del Vecchio F, Clementi F, Sangiuolo F, Amati F, Filareto A, Grelli S, Spitalieri P, Filesi I, Favalli C, Lauro R, Mehta JL, Romeo F, Novelli G. In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction. Circ Res. 2005 Jul 22; 97(2):152-8.
    View in: PubMed
    Score: 0.013
  66. Muscoli C, Sacco I, Alecce W, Palma E, Nistic? R, Costa N, Clementi F, Rotiroti D, Romeo F, Salvemini D, Mehta JL, Mollace V. The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1. J Pharmacol Exp Ther. 2004 Oct; 311(1):44-50.
    View in: PubMed
    Score: 0.013
  67. Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells. Circ Res. 2004 Feb 20; 94(3):370-6.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.