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Connection

Jawahar Mehta to Lipoproteins, LDL

This is a "connection" page, showing publications Jawahar Mehta has written about Lipoproteins, LDL.

 
Connection Strength
  
 
 
12.323
  
  1. Kattoor AJ, Kanuri SH, Mehta JL. Role of Ox-LDL and LOX-1 in Atherogenesis. Curr Med Chem. 2019; 26(9):1693-1700.
    View in: PubMed
    Score: 0.562
  2. Ding Z, Liu S, Wang X, Theus S, Deng X, Fan Y, Zhou S, Mehta JL. PCSK9 regulates expression of scavenger receptors and ox-LDL uptake in macrophages. Cardiovasc Res. 2018 07 01; 114(8):1145-1153.
    View in: PubMed
    Score: 0.543
  3. Wang X, Ding Z, Lin J, Guo Z, Mehta JL. LOX-1 in macrophage migration in response to ox-LDL and the involvement of calpains. Biochem Biophys Res Commun. 2015 Nov 06; 467(1):135-9.
    View in: PubMed
    Score: 0.448
  4. Dai Y, Dai D, Wang X, Ding Z, Li C, Mehta JL. GLP-1 agonists inhibit ox-LDL uptake in macrophages by activating protein kinase A. J Cardiovasc Pharmacol. 2014 Jul; 64(1):47-52.
    View in: PubMed
    Score: 0.411
  5. Mehta JL, Basnakian AG. Interaction of carbamylated LDL with LOX-1 in the induction of endothelial dysfunction and atherosclerosis. Eur Heart J. 2014 Nov 14; 35(43):2996-7.
    View in: PubMed
    Score: 0.404
  6. Dai Y, Palade P, Wang X, Mercanti F, Ding Z, Dai D, Mehta JL. High fat diet causes renal fibrosis in LDLr-null mice through MAPK-NF-?B pathway mediated by Ox-LDL. J Cardiovasc Pharmacol. 2014 Feb; 63(2):158-66.
    View in: PubMed
    Score: 0.400
  7. Ding Z, Liu S, Wang X, Khaidakov M, Dai Y, Mehta JL. Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis. Sci Rep. 2013; 3:1077.
    View in: PubMed
    Score: 0.372
  8. Dai Y, Su W, Ding Z, Wang X, Mercanti F, Chen M, Raina S, Mehta JL. Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-?. Biochem Biophys Res Commun. 2013 Feb 15; 431(3):496-500.
    View in: PubMed
    Score: 0.372
  9. Ding Z, Wang X, Schnackenberg L, Khaidakov M, Liu S, Singla S, Dai Y, Mehta JL. Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7 g. Int J Cardiol. 2013 Sep 30; 168(2):1378-85.
    View in: PubMed
    Score: 0.371
  10. Ding Z, Liu S, Sun C, Chen Z, Fan Y, Deng X, Wang X, Mehta JL. Concentration polarization of ox-LDL activates autophagy and apoptosis via regulating LOX-1 expression. Sci Rep. 2013; 3:2091.
    View in: PubMed
    Score: 0.371
  11. Khaidakov M, Mitra S, Wang X, Ding Z, Bora N, Lyzogubov V, Romeo F, Schichman SA, Mehta JL. Large impact of low concentration oxidized LDL on angiogenic potential of human endothelial cells: a microarray study. PLoS One. 2012; 7(10):e47421.
    View in: PubMed
    Score: 0.366
  12. Khaidakov M, Mehta JL. Oxidized LDL triggers pro-oncogenic signaling in human breast mammary epithelial cells partly via stimulation of MiR-21. PLoS One. 2012; 7(10):e46973.
    View in: PubMed
    Score: 0.365
  13. Ding Z, Wang X, Khaidakov M, Liu S, Mehta JL. MicroRNA hsa-let-7g targets lectin-like oxidized low-density lipoprotein receptor-1 expression and inhibits apoptosis in human smooth muscle cells. Exp Biol Med (Maywood). 2012 Sep; 237(9):1093-100.
    View in: PubMed
    Score: 0.363
  14. Ding Z, Wang X, Khaidakov M, Liu S, Dai Y, Mehta JL. Degradation of heparan sulfate proteoglycans enhances oxidized-LDL-mediated autophagy and apoptosis in human endothelial cells. Biochem Biophys Res Commun. 2012 Sep 14; 426(1):106-11.
    View in: PubMed
    Score: 0.361
  15. L? J, Mehta JL. LOX-1: a critical player in the genesis and progression of myocardial ischemia. Cardiovasc Drugs Ther. 2011 Oct; 25(5):431-40.
    View in: PubMed
    Score: 0.340
  16. Khaidakov M, Mehta JL. Do atherosclerosis and obesity-associated susceptibility to cancer share causative link to oxLDL and LOX-1? Cardiovasc Drugs Ther. 2011 Oct; 25(5):477-87.
    View in: PubMed
    Score: 0.340
  17. Mitra S, Goyal T, Mehta JL. Oxidized LDL, LOX-1 and atherosclerosis. Cardiovasc Drugs Ther. 2011 Oct; 25(5):419-29.
    View in: PubMed
    Score: 0.340
  18. Mitra S, Deshmukh A, Sachdeva R, Lu J, Mehta JL. Oxidized low-density lipoprotein and atherosclerosis implications in antioxidant therapy. Am J Med Sci. 2011 Aug; 342(2):135-42.
    View in: PubMed
    Score: 0.336
  19. Mitra S, Khaidakov M, Lu J, Ayyadevara S, Szwedo J, Wang XW, Chen C, Khaidakov S, Kasula SR, Stone A, Pogribny I, Mehta JL. Prior exposure to oxidized low-density lipoprotein limits apoptosis in subsequent generations of endothelial cells by altering promoter methylation. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H506-13.
    View in: PubMed
    Score: 0.331
  20. Li D, Mehta JL. Intracellular signaling of LOX-1 in endothelial cell apoptosis. Circ Res. 2009 Mar 13; 104(5):566-8.
    View in: PubMed
    Score: 0.285
  21. Dandapat A, Hu C, Sun L, Mehta JL. Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway. Arterioscler Thromb Vasc Biol. 2007 Nov; 27(11):2435-42.
    View in: PubMed
    Score: 0.256
  22. Mehta JL. Oxidized or native low-density lipoprotein cholesterol: which is more important in atherogenesis? J Am Coll Cardiol. 2006 Sep 05; 48(5):980-2.
    View in: PubMed
    Score: 0.238
  23. Chen J, Mehta JL. Interaction of oxidized low-density lipoprotein and the renin-angiotensin system in coronary artery disease. Curr Hypertens Rep. 2006 May; 8(2):139-43.
    View in: PubMed
    Score: 0.233
  24. Li D, Mehta JL. Oxidized LDL, a critical factor in atherogenesis. Cardiovasc Res. 2005 Dec 01; 68(3):353-4.
    View in: PubMed
    Score: 0.225
  25. Mehta JL, Chen J, Yu F, Li DY. Aspirin inhibits ox-LDL-mediated LOX-1 expression and metalloproteinase-1 in human coronary endothelial cells. Cardiovasc Res. 2004 Nov 01; 64(2):243-9.
    View in: PubMed
    Score: 0.210
  26. Mehta JL. The role of LOX-1, a novel lectin-like receptor for oxidized low density lipoprotein, in atherosclerosis. Can J Cardiol. 2004 Aug; 20 Suppl B:32B-36B.
    View in: PubMed
    Score: 0.207
  27. Hu B, Li D, Sawamura T, Mehta JL. Oxidized LDL through LOX-1 modulates LDL-receptor expression in human coronary artery endothelial cells. Biochem Biophys Res Commun. 2003 Aug 08; 307(4):1008-12.
    View in: PubMed
    Score: 0.193
  28. Joseph J, Ranganathan S, Mehta JL. Low density lipoproteins modulate collagen metabolism in fibroblasts. J Cardiovasc Pharmacol Ther. 2003 Jun; 8(2):161-6.
    View in: PubMed
    Score: 0.191
  29. Li D, Liu L, Chen H, Sawamura T, Mehta JL. LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol. 2003 May 01; 23(5):816-21.
    View in: PubMed
    Score: 0.188
  30. Li D, Liu L, Chen H, Sawamura T, Ranganathan S, Mehta JL. LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation. 2003 Feb 04; 107(4):612-7.
    View in: PubMed
    Score: 0.187
  31. Li D, Singh RM, Liu L, Chen H, Singh BM, Kazzaz N, Mehta JL. Oxidized-LDL through LOX-1 increases the expression of angiotensin converting enzyme in human coronary artery endothelial cells. Cardiovasc Res. 2003 Jan; 57(1):238-43.
    View in: PubMed
    Score: 0.185
  32. Li D, Mehta JL. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect against oxidized low-density lipoprotein-induced endothelial dysfunction. Endothelium. 2003; 10(1):17-21.
    View in: PubMed
    Score: 0.185
  33. Li D, Chen H, Romeo F, Sawamura T, Saldeen T, Mehta JL. Statins modulate oxidized low-density lipoprotein-mediated adhesion molecule expression in human coronary artery endothelial cells: role of LOX-1. J Pharmacol Exp Ther. 2002 Aug; 302(2):601-5.
    View in: PubMed
    Score: 0.180
  34. Tomar A, Sahoo S, Aathi M, Kuila S, Khan MA, Ravi GRR, Jeyaraman J, Mehta JL, Varughese KI, Arockiasamy A. Exploring the druggability of oxidized low-density lipoprotein (ox-LDL) receptor, LOX-1, a proatherogenic drug target involved in atherosclerosis. Biochem Biophys Res Commun. 2022 10 01; 623:59-65.
    View in: PubMed
    Score: 0.179
  35. Dai Y, Wu X, Dai D, Li J, Mehta JL. MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1. Redox Biol. 2018 06; 16:255-262.
    View in: PubMed
    Score: 0.133
  36. Kattoor AJ, Pothineni NVK, Palagiri D, Mehta JL. Oxidative Stress in Atherosclerosis. Curr Atheroscler Rep. 2017 Sep 18; 19(11):42.
    View in: PubMed
    Score: 0.128
  37. Dai Y, Zhang Z, Cao Y, Mehta JL, Li J. MiR-590-5p Inhibits Oxidized- LDL Induced Angiogenesis by Targeting LOX-1. Sci Rep. 2016 Mar 02; 6:22607.
    View in: PubMed
    Score: 0.115
  38. Thakkar S, Wang X, Khaidakov M, Dai Y, Gokulan K, Mehta JL, Varughese KI. Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein. Sci Rep. 2015 Nov 18; 5:16740.
    View in: PubMed
    Score: 0.113
  39. Ding Z, Liu S, Wang X, Deng X, Fan Y, Shahanawaz J, Shmookler Reis RJ, Varughese KI, Sawamura T, Mehta JL. Cross-talk between LOX-1 and PCSK9 in vascular tissues. Cardiovasc Res. 2015 Sep 01; 107(4):556-67.
    View in: PubMed
    Score: 0.110
  40. Dai Y, Wang X, Ding Z, Dai D, Mehta JL. DPP-4 inhibitors repress foam cell formation by inhibiting scavenger receptors through protein kinase C pathway. Acta Diabetol. 2014; 51(3):471-8.
    View in: PubMed
    Score: 0.099
  41. Monteleone I, Muscoli S, Terribili N, Zorzi F, Mariano E, Mehta JL, Pallone F, Monteleone G, Romeo F. Local immune activity in acute coronary syndrome: oxLDL abrogates LPS-tolerance in mononuclear cells isolated from culprit lesion. Int J Cardiol. 2013 Oct 25; 169(1):44-51.
    View in: PubMed
    Score: 0.097
  42. Dai Y, Mercanti F, Dai D, Wang X, Ding Z, Pothineni NV, Mehta JL. LOX-1, a bridge between GLP-1R and mitochondrial ROS generation in human vascular smooth muscle cells. Biochem Biophys Res Commun. 2013 Jul 19; 437(1):62-6.
    View in: PubMed
    Score: 0.096
  43. Yan M, Mehta JL, Hu C. LOX-1 and obesity. Cardiovasc Drugs Ther. 2011 Oct; 25(5):469-76.
    View in: PubMed
    Score: 0.085
  44. Luo P, Yan M, Frohlich ED, Mehta JL, Hu C. Novel concepts in the genesis of hypertension: role of LOX-1. Cardiovasc Drugs Ther. 2011 Oct; 25(5):441-9.
    View in: PubMed
    Score: 0.085
  45. Deshmukh A, Mehta JL. Statins and renal disease: friend or foe? Curr Atheroscler Rep. 2011 Feb; 13(1):57-63.
    View in: PubMed
    Score: 0.081
  46. Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L, Beger R, Hermonat PL, Thomas M, Sawamura T. Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res. 2007 Jun 08; 100(11):1634-42.
    View in: PubMed
    Score: 0.063
  47. Chen J, Liu Y, Liu H, Hermonat PL, Mehta JL. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) transcriptional regulation by Oct-1 in human endothelial cells: implications for atherosclerosis. Biochem J. 2006 Jan 01; 393(Pt 1):255-65.
    View in: PubMed
    Score: 0.057
  48. Chen K, Chen J, Liu Y, Xie J, Li D, Sawamura T, Hermonat PL, Mehta JL. Adhesion molecule expression in fibroblasts: alteration in fibroblast biology after transfection with LOX-1 plasmids. Hypertension. 2005 Sep; 46(3):622-7.
    View in: PubMed
    Score: 0.056
  49. Cola C, Almeida M, Li D, Romeo F, Mehta JL. Regulatory role of endothelium in the expression of genes affecting arterial calcification. Biochem Biophys Res Commun. 2004 Jul 23; 320(2):424-7.
    View in: PubMed
    Score: 0.052
  50. Zhang W, Li D, Mehta JL. Role of AIF in human coronary artery endothelial cell apoptosis. Am J Physiol Heart Circ Physiol. 2004 Jan; 286(1):H354-8.
    View in: PubMed
    Score: 0.050
  51. Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells. Circ Res. 2004 Feb 20; 94(3):370-6.
    View in: PubMed
    Score: 0.050
  52. Mehta JL, Hu B, Chen J, Li D. Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation. Arterioscler Thromb Vasc Biol. 2003 Dec; 23(12):2203-8.
    View in: PubMed
    Score: 0.049
  53. Chen H, Li D, Chen J, Roberts GJ, Saldeen T, Mehta JL. EPA and DHA attenuate ox-LDL-induced expression of adhesion molecules in human coronary artery endothelial cells via protein kinase B pathway. J Mol Cell Cardiol. 2003 Jul; 35(7):769-75.
    View in: PubMed
    Score: 0.048
  54. Singh BM, Mehta JL. Interactions between the renin-angiotensin system and dyslipidemia: relevance in the therapy of hypertension and coronary heart disease. Arch Intern Med. 2003 Jun 09; 163(11):1296-304.
    View in: PubMed
    Score: 0.048
  55. Khan MA, Mohammad I, Banerjee S, Tomar A, Varughese KI, Mehta JL, Chandele A, Arockiasamy A. Oxidized LDL receptors: a recent update. Curr Opin Lipidol. 2023 08 01; 34(4):147-155.
    View in: PubMed
    Score: 0.047
  56. Zhang W, Shokeen M, Li D, Mehta JL. Identification of apoptosis-inducing factor in human coronary artery endothelial cells. Biochem Biophys Res Commun. 2003 Jan 31; 301(1):147-51.
    View in: PubMed
    Score: 0.047
  57. Mehta JL, Li DY, Chen HJ, Joseph J, Romeo F. Inhibition of LOX-1 by statins may relate to upregulation of eNOS. Biochem Biophys Res Commun. 2001 Dec 14; 289(4):857-61.
    View in: PubMed
    Score: 0.043
  58. Jiang J, Yan M, Mehta JL, Hu C. Angiogenesis is a link between atherosclerosis and tumorigenesis: role of LOX-1. Cardiovasc Drugs Ther. 2011 Oct; 25(5):461-8.
    View in: PubMed
    Score: 0.021
  59. Mango R, Biocca S, del Vecchio F, Clementi F, Sangiuolo F, Amati F, Filareto A, Grelli S, Spitalieri P, Filesi I, Favalli C, Lauro R, Mehta JL, Romeo F, Novelli G. In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction. Circ Res. 2005 Jul 22; 97(2):152-8.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.