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Connection

Anna Radominska-Pandya to Glucuronosyltransferase

This is a "connection" page, showing publications Anna Radominska-Pandya has written about Glucuronosyltransferase.

 
Connection Strength
  
 
 
9.958
  
  1. Dates CR, Fahmi T, Pyrek SJ, Yao-Borengasser A, Borowa-Mazgaj B, Bratton SM, Kadlubar SA, Mackenzie PI, Haun RS, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines. Cancer Biol Ther. 2015; 16(5):714-23.
    View in: PubMed
    Score: 0.455
  2. Greer AK, Dates CR, Starlard-Davenport A, Edavana VK, Bratton SM, Dhakal IB, Finel M, Kadlubar SA, Radominska-Pandya A. A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives. Drug Metab Dispos. 2014 Sep; 42(9):1392-400.
    View in: PubMed
    Score: 0.438
  3. Greer AK, Madadi NR, Bratton SM, Eddy SD, Mazerska Z, Hendrickson HP, Crooks PA, Radominska-Pandya A. Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases. Chem Res Toxicol. 2014 Apr 21; 27(4):536-45.
    View in: PubMed
    Score: 0.430
  4. Brents LK, Medina-Bolivar F, Seely KA, Nair V, Bratton SM, Nopo-Olazabal L, Patel RY, Liu H, Doerksen RJ, Prather PL, Radominska-Pandya A. Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Xenobiotica. 2012 Feb; 42(2):139-56.
    View in: PubMed
    Score: 0.363
  5. Bratton SM, Mosher CM, Khallouki F, Finel M, Court MH, Moran JH, Radominska-Pandya A. Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther. 2012 Jan; 340(1):46-55.
    View in: PubMed
    Score: 0.363
  6. Chimalakonda KC, Bratton SM, Le VH, Yiew KH, Dineva A, Moran CL, James LP, Moran JH, Radominska-Pandya A. Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases. Drug Metab Dispos. 2011 Oct; 39(10):1967-76.
    View in: PubMed
    Score: 0.358
  7. Radominska-Pandya A, Bratton SM, Redinbo MR, Miley MJ. The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families. Drug Metab Rev. 2010 Feb; 42(1):133-44.
    View in: PubMed
    Score: 0.324
  8. Radominska-Pandya A. Preface. Drug Metab Rev. 2010 Feb; 42(1):1-2.
    View in: PubMed
    Score: 0.324
  9. Miller GP, Lichti CF, Zielinska AK, Mazur A, Bratton SM, Gallus-Zawada A, Finel M, Moran JH, Radominska-Pandya A. Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin. Drug Metab Dispos. 2008 Nov; 36(11):2211-8.
    View in: PubMed
    Score: 0.293
  10. Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues. Steroids. 2008 Jul; 73(6):611-20.
    View in: PubMed
    Score: 0.282
  11. Lu Y, Bratton S, Heydel JM, Radominska-Pandya A. Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells. Drug Metab Pharmacokinet. 2008; 23(5):364-72.
    View in: PubMed
    Score: 0.280
  12. Xiong Y, Patana AS, Miley MJ, Zielinska AK, Bratton SM, Miller GP, Goldman A, Finel M, Redinbo MR, Radominska-Pandya A. The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis. Drug Metab Dispos. 2008 Mar; 36(3):517-22.
    View in: PubMed
    Score: 0.278
  13. Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. Steroids. 2008 Jan; 73(1):139-47.
    View in: PubMed
    Score: 0.275
  14. Li X, Bratton S, Radominska-Pandya A. Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes. Drug Metab Pharmacokinet. 2007 Jun; 22(3):152-61.
    View in: PubMed
    Score: 0.269
  15. Starlard-Davenport A, Xiong Y, Bratton S, Gallus-Zawada A, Finel M, Radominska-Pandya A. Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10. Steroids. 2007 Jan; 72(1):85-94.
    View in: PubMed
    Score: 0.260
  16. Xiong Y, Bernardi D, Bratton S, Ward MD, Battaglia E, Finel M, Drake RR, Radominska-Pandya A. Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis. Biochemistry. 2006 Feb 21; 45(7):2322-32.
    View in: PubMed
    Score: 0.246
  17. Finel M, Li X, Gardner-Stephen D, Bratton S, Mackenzie PI, Radominska-Pandya A. Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity. J Pharmacol Exp Ther. 2005 Dec; 315(3):1143-9.
    View in: PubMed
    Score: 0.238
  18. Lu Y, Heydel JM, Li X, Bratton S, Lindblom T, Radominska-Pandya A. Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element. Drug Metab Dispos. 2005 Jul; 33(7):937-46.
    View in: PubMed
    Score: 0.232
  19. Radominska-Pandya A, Bratton S, Little JM. A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years. Curr Drug Metab. 2005 Apr; 6(2):141-60.
    View in: PubMed
    Score: 0.231
  20. Radominska-Pandya A, Ouzzine M, Fournel-Gigleux S, Magdalou J. Structure of UDP-glucuronosyltransferases in membranes. Methods Enzymol. 2005; 400:116-47.
    View in: PubMed
    Score: 0.228
  21. Little JM, Kurkela M, Sonka J, J?ntti S, Ketola R, Bratton S, Finel M, Radominska-Pandya A. Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. J Lipid Res. 2004 Sep; 45(9):1694-703.
    View in: PubMed
    Score: 0.220
  22. Gardner-Stephen D, Heydel JM, Goyal A, Lu Y, Xie W, Lindblom T, Mackenzie P, Radominska-Pandya A. Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression. Drug Metab Dispos. 2004 Mar; 32(3):340-7.
    View in: PubMed
    Score: 0.215
  23. Mackenzie PI, Gregory PA, Gardner-Stephen DA, Lewinsky RH, Jorgensen BR, Nishiyama T, Xie W, Radominska-Pandya A. Regulation of UDP glucuronosyltransferase genes. Curr Drug Metab. 2003 Jun; 4(3):249-57.
    View in: PubMed
    Score: 0.204
  24. Mackenzie P, Little JM, Radominska-Pandya A. Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. Biochem Pharmacol. 2003 Feb 01; 65(3):417-21.
    View in: PubMed
    Score: 0.199
  25. Radominska-Pandya A, Pokrovskaya ID, Xu J, Little JM, Jude AR, Kurten RC, Czernik PJ. Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes. Arch Biochem Biophys. 2002 Mar 01; 399(1):37-48.
    View in: PubMed
    Score: 0.187
  26. Jude AR, Little JM, Czernik PJ, Tephly TR, Grant DF, Radominska-Pandya A. Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved. Arch Biochem Biophys. 2001 May 15; 389(2):176-86.
    View in: PubMed
    Score: 0.177
  27. Jude AR, Little JM, Bull AW, Podgorski I, Radominska-Pandya A. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. Drug Metab Dispos. 2001 May; 29(5):652-5.
    View in: PubMed
    Score: 0.176
  28. Czernik PJ, Little JM, Barone GW, Raufman JP, Radominska-Pandya A. Glucuronidation of estrogens and retinoic acid and expression of UDP-glucuronosyltransferase 2B7 in human intestinal mucosa. Drug Metab Dispos. 2000 Oct; 28(10):1210-6.
    View in: PubMed
    Score: 0.169
  29. Samokyszyn VM, Gall WE, Zawada G, Freyaldenhoven MA, Chen G, Mackenzie PI, Tephly TR, Radominska-Pandya A. 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. J Biol Chem. 2000 Mar 10; 275(10):6908-14.
    View in: PubMed
    Score: 0.163
  30. Radominska-Pandya A, Czernik PJ, Little JM, Battaglia E, Mackenzie PI. Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev. 1999 Nov; 31(4):817-99.
    View in: PubMed
    Score: 0.159
  31. Senay C, Battaglia E, Chen G, Breton R, Fournel-Gigleux S, Magdalou J, Radominska-Pandya A. Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin. Arch Biochem Biophys. 1999 Aug 01; 368(1):75-84.
    View in: PubMed
    Score: 0.156
  32. Gall WE, Zawada G, Mojarrabi B, Tephly TR, Green MD, Coffman BL, Mackenzie PI, Radominska-Pandya A. Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7. J Steroid Biochem Mol Biol. 1999 Jul-Aug; 70(1-3):101-8.
    View in: PubMed
    Score: 0.155
  33. Little JM, Lester R, Kuipers F, Vonk R, Mackenzie PI, Drake RR, Frame L, Radominska-Pandya A. Variability of human hepatic UDP-glucuronosyltransferase activity. Acta Biochim Pol. 1999; 46(2):351-63.
    View in: PubMed
    Score: 0.150
  34. Radominska-Pandya A, Little JM, Pandya JT, Tephly TR, King CD, Barone GW, Raufman JP. UDP-glucuronosyltransferases in human intestinal mucosa. Biochim Biophys Acta. 1998 Nov 02; 1394(2-3):199-208.
    View in: PubMed
    Score: 0.148
  35. Battaglia E, Terrier N, Mizeracka M, Senay C, Magdalou J, Fournel-Gigleux S, Radominska-Pandya A. Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6. Drug Metab Dispos. 1998 Aug; 26(8):812-7.
    View in: PubMed
    Score: 0.146
  36. Pawlowska M, Chu R, Fedejko-Kap B, Augustin E, Mazerska Z, Radominska-Pandya A, Chambers TC. Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use. Drug Metab Dispos. 2013 Feb; 41(2):414-21.
    View in: PubMed
    Score: 0.098
  37. Fedejko-Kap B, Bratton SM, Finel M, Radominska-Pandya A, Mazerska Z. Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10. Drug Metab Dispos. 2012 Sep; 40(9):1736-43.
    View in: PubMed
    Score: 0.095
  38. H?glund C, Sneitz N, Radominska-Pandya A, Laakonen L, Finel M. Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens. Steroids. 2011 Dec 11; 76(13):1465-73.
    View in: PubMed
    Score: 0.090
  39. Miller GP, Jones DR, Sullivan SZ, Mazur A, Owen SN, Mitchell NC, Radominska-Pandya A, Moran JH. Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans. Chem Res Toxicol. 2009 Jul; 22(7):1239-45.
    View in: PubMed
    Score: 0.078
  40. Mazur A, Lichti CF, Prather PL, Zielinska AK, Bratton SM, Gallus-Zawada A, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids. Drug Metab Dispos. 2009 Jul; 37(7):1496-504.
    View in: PubMed
    Score: 0.076
  41. It?aho K, Court MH, Uutela P, Kostiainen R, Radominska-Pandya A, Finel M. Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. Drug Metab Dispos. 2009 Apr; 37(4):768-75.
    View in: PubMed
    Score: 0.075
  42. Zielinska A, Lichti CF, Bratton S, Mitchell NC, Gallus-Zawada A, Le VH, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther. 2008 Jan; 324(1):139-48.
    View in: PubMed
    Score: 0.069
  43. Miley MJ, Zielinska AK, Keenan JE, Bratton SM, Radominska-Pandya A, Redinbo MR. Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7. J Mol Biol. 2007 Jun 01; 369(2):498-511.
    View in: PubMed
    Score: 0.066
  44. Sabolovic N, Humbert AC, Radominska-Pandya A, Magdalou J. Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells. Biopharm Drug Dispos. 2006 May; 27(4):181-9.
    View in: PubMed
    Score: 0.062
  45. Sabolovic N, Heydel JM, Li X, Little JM, Humbert AC, Radominska-Pandya A, Magdalou J. Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract. Biochim Biophys Acta. 2004 Nov 18; 1675(1-3):120-9.
    View in: PubMed
    Score: 0.056
  46. Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4150-5.
    View in: PubMed
    Score: 0.050
  47. Antonio L, Xu J, Little JM, Burchell B, Magdalou J, Radominska-Pandya A. Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7. Arch Biochem Biophys. 2003 Mar 15; 411(2):251-61.
    View in: PubMed
    Score: 0.050
  48. Radominska-Pandya A, Chen G, Samokyszyn VM, Little JM, Gall WE, Zawada G, Terrier N, Magdalou J, Czernik P. Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II. Protein Sci. 2001 Jan; 10(1):200-11.
    View in: PubMed
    Score: 0.043
  49. Jude AR, Little JM, Freeman JP, Evans JE, Radominska-Pandya A, Grant DF. Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases. Arch Biochem Biophys. 2000 Aug 15; 380(2):294-302.
    View in: PubMed
    Score: 0.042
  50. Cheng Z, Radominska-Pandya A, Tephly TR. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10. Drug Metab Dispos. 1999 Oct; 27(10):1165-70.
    View in: PubMed
    Score: 0.040
  51. Terrier N, Benoit E, Senay C, Lapicque F, Radominska-Pandya A, Magdalou J, Fournel-Gigleux S. Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide. Mol Pharmacol. 1999 Jul; 56(1):226-34.
    View in: PubMed
    Score: 0.039
  52. Nowell SA, Massengill JS, Williams S, Radominska-Pandya A, Tephly TR, Cheng Z, Strassburg CP, Tukey RH, MacLeod SL, Lang NP, Kadlubar FF. Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved. Carcinogenesis. 1999 Jun; 20(6):1107-14.
    View in: PubMed
    Score: 0.039
  53. Jones S, Yarbrough AL, Shoeib A, Bush JM, Fantegrossi WE, Prather PL, Radominska-Pandya A, Fujiwara R. Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22). Xenobiotica. 2019 Dec; 49(12):1388-1395.
    View in: PubMed
    Score: 0.038
  54. Cheng Z, Radominska-Pandya A, Tephly TR. Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8. Arch Biochem Biophys. 1998 Aug 15; 356(2):301-5.
    View in: PubMed
    Score: 0.037
  55. Seely KA, Brents LK, Radominska-Pandya A, Endres GW, Keyes GS, Moran JH, Prather PL. A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. Chem Res Toxicol. 2012 Apr 16; 25(4):825-7.
    View in: PubMed
    Score: 0.023
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.