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Connection

Anna Radominska-Pandya to Humans

This is a "connection" page, showing publications Anna Radominska-Pandya has written about Humans.

 
Connection Strength
  
 
 
0.711
  
  1. Pinson A, Yarbrough AL, Bush JM, Cabanlong CV, Shoeib A, Jackson BK, Fukuda S, Gogoi J, Fantegrossi WE, McCain K, Prather PL, Fujiwara R, Radominska-Pandya A. Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity. Pharmacol Biochem Behav. 2020 08; 195:172949.
    View in: PubMed
    Score: 0.030
  2. Patton AL, Seely KA, Yarbrough AL, Fantegrossi W, James LP, McCain KR, Fujiwara R, Prather PL, Moran JH, Radominska-Pandya A. Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants. Biochem Biophys Res Commun. 2018 04 06; 498(3):597-602.
    View in: PubMed
    Score: 0.026
  3. Dates CR, Fahmi T, Pyrek SJ, Yao-Borengasser A, Borowa-Mazgaj B, Bratton SM, Kadlubar SA, Mackenzie PI, Haun RS, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines. Cancer Biol Ther. 2015; 16(5):714-23.
    View in: PubMed
    Score: 0.020
  4. Greer AK, Dates CR, Starlard-Davenport A, Edavana VK, Bratton SM, Dhakal IB, Finel M, Kadlubar SA, Radominska-Pandya A. A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives. Drug Metab Dispos. 2014 Sep; 42(9):1392-400.
    View in: PubMed
    Score: 0.020
  5. Biris AS, Radominska-Pandya A. Special issue: nanotechnology and disease. Drug Metab Rev. 2014 May; 46(2):127.
    View in: PubMed
    Score: 0.019
  6. Greer AK, Madadi NR, Bratton SM, Eddy SD, Mazerska Z, Hendrickson HP, Crooks PA, Radominska-Pandya A. Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases. Chem Res Toxicol. 2014 Apr 21; 27(4):536-45.
    View in: PubMed
    Score: 0.019
  7. Prather PL, FrancisDevaraj F, Dates CR, Greer AK, Bratton SM, Ford BM, Franks LN, Radominska-Pandya A. CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen. Biochem Biophys Res Commun. 2013 Nov 15; 441(2):339-43.
    View in: PubMed
    Score: 0.019
  8. Brents LK, Medina-Bolivar F, Seely KA, Nair V, Bratton SM, Nopo-Olazabal L, Patel RY, Liu H, Doerksen RJ, Prather PL, Radominska-Pandya A. Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Xenobiotica. 2012 Feb; 42(2):139-56.
    View in: PubMed
    Score: 0.016
  9. Bratton SM, Mosher CM, Khallouki F, Finel M, Court MH, Moran JH, Radominska-Pandya A. Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther. 2012 Jan; 340(1):46-55.
    View in: PubMed
    Score: 0.016
  10. Chimalakonda KC, Bratton SM, Le VH, Yiew KH, Dineva A, Moran CL, James LP, Moran JH, Radominska-Pandya A. Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases. Drug Metab Dispos. 2011 Oct; 39(10):1967-76.
    View in: PubMed
    Score: 0.016
  11. Radominska-Pandya A, Bratton SM, Redinbo MR, Miley MJ. The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families. Drug Metab Rev. 2010 Feb; 42(1):133-44.
    View in: PubMed
    Score: 0.015
  12. Radominska-Pandya A. Preface. Drug Metab Rev. 2010 Feb; 42(1):1-2.
    View in: PubMed
    Score: 0.015
  13. Miller GP, Lichti CF, Zielinska AK, Mazur A, Bratton SM, Gallus-Zawada A, Finel M, Moran JH, Radominska-Pandya A. Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin. Drug Metab Dispos. 2008 Nov; 36(11):2211-8.
    View in: PubMed
    Score: 0.013
  14. Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues. Steroids. 2008 Jul; 73(6):611-20.
    View in: PubMed
    Score: 0.013
  15. Lu Y, Bratton S, Heydel JM, Radominska-Pandya A. Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells. Drug Metab Pharmacokinet. 2008; 23(5):364-72.
    View in: PubMed
    Score: 0.013
  16. Xiong Y, Patana AS, Miley MJ, Zielinska AK, Bratton SM, Miller GP, Goldman A, Finel M, Redinbo MR, Radominska-Pandya A. The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis. Drug Metab Dispos. 2008 Mar; 36(3):517-22.
    View in: PubMed
    Score: 0.013
  17. Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. Steroids. 2008 Jan; 73(1):139-47.
    View in: PubMed
    Score: 0.012
  18. Li X, Bratton S, Radominska-Pandya A. Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes. Drug Metab Pharmacokinet. 2007 Jun; 22(3):152-61.
    View in: PubMed
    Score: 0.012
  19. Starlard-Davenport A, Xiong Y, Bratton S, Gallus-Zawada A, Finel M, Radominska-Pandya A. Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10. Steroids. 2007 Jan; 72(1):85-94.
    View in: PubMed
    Score: 0.012
  20. Xiong Y, Bernardi D, Bratton S, Ward MD, Battaglia E, Finel M, Drake RR, Radominska-Pandya A. Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis. Biochemistry. 2006 Feb 21; 45(7):2322-32.
    View in: PubMed
    Score: 0.011
  21. Finel M, Li X, Gardner-Stephen D, Bratton S, Mackenzie PI, Radominska-Pandya A. Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity. J Pharmacol Exp Ther. 2005 Dec; 315(3):1143-9.
    View in: PubMed
    Score: 0.011
  22. Lu Y, Heydel JM, Li X, Bratton S, Lindblom T, Radominska-Pandya A. Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element. Drug Metab Dispos. 2005 Jul; 33(7):937-46.
    View in: PubMed
    Score: 0.010
  23. Radominska-Pandya A, Bratton S, Little JM. A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years. Curr Drug Metab. 2005 Apr; 6(2):141-60.
    View in: PubMed
    Score: 0.010
  24. Radominska-Pandya A, Ouzzine M, Fournel-Gigleux S, Magdalou J. Structure of UDP-glucuronosyltransferases in membranes. Methods Enzymol. 2005; 400:116-47.
    View in: PubMed
    Score: 0.010
  25. Little JM, Kurkela M, Sonka J, J?ntti S, Ketola R, Bratton S, Finel M, Radominska-Pandya A. Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. J Lipid Res. 2004 Sep; 45(9):1694-703.
    View in: PubMed
    Score: 0.010
  26. Gardner-Stephen D, Heydel JM, Goyal A, Lu Y, Xie W, Lindblom T, Mackenzie P, Radominska-Pandya A. Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression. Drug Metab Dispos. 2004 Mar; 32(3):340-7.
    View in: PubMed
    Score: 0.010
  27. Mackenzie PI, Gregory PA, Gardner-Stephen DA, Lewinsky RH, Jorgensen BR, Nishiyama T, Xie W, Radominska-Pandya A. Regulation of UDP glucuronosyltransferase genes. Curr Drug Metab. 2003 Jun; 4(3):249-57.
    View in: PubMed
    Score: 0.009
  28. Antonio L, Xu J, Little JM, Burchell B, Magdalou J, Radominska-Pandya A. Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7. Arch Biochem Biophys. 2003 Mar 15; 411(2):251-61.
    View in: PubMed
    Score: 0.009
  29. Chen G, Zhang D, Jing N, Yin S, Falany CN, Radominska-Pandya A. Human gastrointestinal sulfotransferases: identification and distribution. Toxicol Appl Pharmacol. 2003 Mar 15; 187(3):186-97.
    View in: PubMed
    Score: 0.009
  30. Mackenzie P, Little JM, Radominska-Pandya A. Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. Biochem Pharmacol. 2003 Feb 01; 65(3):417-21.
    View in: PubMed
    Score: 0.009
  31. Coles BF, Chen G, Kadlubar FF, Radominska-Pandya A. Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals. Arch Biochem Biophys. 2002 Jul 15; 403(2):270-6.
    View in: PubMed
    Score: 0.009
  32. Radominska-Pandya A, Chen G. Photoaffinity labeling of human retinoid X receptor beta (RXRbeta) with 9-cis-retinoic acid: identification of phytanic acid, docosahexaenoic acid, and lithocholic acid as ligands for RXRbeta. Biochemistry. 2002 Apr 16; 41(15):4883-90.
    View in: PubMed
    Score: 0.008
  33. Radominska-Pandya A, Pokrovskaya ID, Xu J, Little JM, Jude AR, Kurten RC, Czernik PJ. Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes. Arch Biochem Biophys. 2002 Mar 01; 399(1):37-48.
    View in: PubMed
    Score: 0.008
  34. Shoeib AM, Yarbrough AL, Ford BM, Franks LN, Urbaniak A, Hensley LL, Benson LN, Mu S, Radominska-Pandya A, Prather PL. Characterization of cannabinoid receptors expressed in Ewing sarcoma TC-71 and A-673 cells as potential targets for anti-cancer drug development. Life Sci. 2021 Nov 15; 285:119993.
    View in: PubMed
    Score: 0.008
  35. Jude AR, Little JM, Czernik PJ, Tephly TR, Grant DF, Radominska-Pandya A. Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved. Arch Biochem Biophys. 2001 May 15; 389(2):176-86.
    View in: PubMed
    Score: 0.008
  36. Jude AR, Little JM, Bull AW, Podgorski I, Radominska-Pandya A. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. Drug Metab Dispos. 2001 May; 29(5):652-5.
    View in: PubMed
    Score: 0.008
  37. Radominska-Pandya A, Chen G, Samokyszyn VM, Little JM, Gall WE, Zawada G, Terrier N, Magdalou J, Czernik P. Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II. Protein Sci. 2001 Jan; 10(1):200-11.
    View in: PubMed
    Score: 0.008
  38. Chen G, Rabjohn PA, York JL, Wooldridge C, Zhang D, Falany CN, Radominska-Pandya A. Carboxyl residues in the active site of human phenol sulfotransferase (SULT1A1). Biochemistry. 2000 Dec 26; 39(51):16000-7.
    View in: PubMed
    Score: 0.008
  39. Pinson AO, Pouncey DL, Schleiff MA, Fantegrossi WE, Prather PL, Radominska-Pandya A, Boysen G, Miller GP. Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics. Molecules. 2020 Oct 20; 25(20).
    View in: PubMed
    Score: 0.008
  40. Chen G, Radominska-Pandya A. Direct photoaffinity labeling of cellular retinoic acid-binding protein I (CRABP-I) with all-trans-retinoic acid: identification of amino acids in the ligand binding site. Biochemistry. 2000 Oct 17; 39(41):12568-74.
    View in: PubMed
    Score: 0.008
  41. Czernik PJ, Little JM, Barone GW, Raufman JP, Radominska-Pandya A. Glucuronidation of estrogens and retinoic acid and expression of UDP-glucuronosyltransferase 2B7 in human intestinal mucosa. Drug Metab Dispos. 2000 Oct; 28(10):1210-6.
    View in: PubMed
    Score: 0.008
  42. Radominska-Pandya A, Chen G, Czernik PJ, Little JM, Samokyszyn VM, Carter CA, Nowak Gd. Direct interaction of all-trans-retinoic acid with protein kinase C (PKC). Implications for PKC signaling and cancer therapy. J Biol Chem. 2000 Jul 21; 275(29):22324-30.
    View in: PubMed
    Score: 0.008
  43. Samokyszyn VM, Gall WE, Zawada G, Freyaldenhoven MA, Chen G, Mackenzie PI, Tephly TR, Radominska-Pandya A. 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. J Biol Chem. 2000 Mar 10; 275(10):6908-14.
    View in: PubMed
    Score: 0.007
  44. Jones S, Yarbrough AL, Fantegrossi WE, Prather PL, Bush JM, Radominska-Pandya A, Fujiwara R. Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135). Pharmacol Res Perspect. 2020 02; 8(1):e00561.
    View in: PubMed
    Score: 0.007
  45. Radominska-Pandya A, Czernik PJ, Little JM, Battaglia E, Mackenzie PI. Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev. 1999 Nov; 31(4):817-99.
    View in: PubMed
    Score: 0.007
  46. Chen G, Battaglia E, Senay C, Falany CN, Radominska-Pandya A. Photoaffinity labeling probe for the substrate binding site of human phenol sulfotransferase (SULT1A1): 7-azido-4-methylcoumarin. Protein Sci. 1999 Oct; 8(10):2151-7.
    View in: PubMed
    Score: 0.007
  47. Senay C, Battaglia E, Chen G, Breton R, Fournel-Gigleux S, Magdalou J, Radominska-Pandya A. Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin. Arch Biochem Biophys. 1999 Aug 01; 368(1):75-84.
    View in: PubMed
    Score: 0.007
  48. Gall WE, Zawada G, Mojarrabi B, Tephly TR, Green MD, Coffman BL, Mackenzie PI, Radominska-Pandya A. Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7. J Steroid Biochem Mol Biol. 1999 Jul-Aug; 70(1-3):101-8.
    View in: PubMed
    Score: 0.007
  49. Jones S, Yarbrough AL, Shoeib A, Bush JM, Fantegrossi WE, Prather PL, Radominska-Pandya A, Fujiwara R. Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22). Xenobiotica. 2019 Dec; 49(12):1388-1395.
    View in: PubMed
    Score: 0.007
  50. Little JM, Lester R, Kuipers F, Vonk R, Mackenzie PI, Drake RR, Frame L, Radominska-Pandya A. Variability of human hepatic UDP-glucuronosyltransferase activity. Acta Biochim Pol. 1999; 46(2):351-63.
    View in: PubMed
    Score: 0.007
  51. Wilson CD, Tai S, Ewing L, Crane J, Lockhart T, Fujiwara R, Radominska-Pandya A, Fantegrossi WE. Convulsant Effects of Abused Synthetic Cannabinoids JWH-018 and 5F-AB-PINACA Are Mediated by Agonist Actions at CB1 Receptors in Mice. J Pharmacol Exp Ther. 2019 02; 368(2):146-156.
    View in: PubMed
    Score: 0.007
  52. Radominska-Pandya A, Little JM, Pandya JT, Tephly TR, King CD, Barone GW, Raufman JP. UDP-glucuronosyltransferases in human intestinal mucosa. Biochim Biophys Acta. 1998 Nov 02; 1394(2-3):199-208.
    View in: PubMed
    Score: 0.007
  53. Battaglia E, Terrier N, Mizeracka M, Senay C, Magdalou J, Fournel-Gigleux S, Radominska-Pandya A. Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6. Drug Metab Dispos. 1998 Aug; 26(8):812-7.
    View in: PubMed
    Score: 0.007
  54. Ford BM, Franks LN, Radominska-Pandya A, Prather PL. Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One. 2016; 11(12):e0167240.
    View in: PubMed
    Score: 0.006
  55. Saeed LM, Mahmood M, Pyrek SJ, Fahmi T, Xu Y, Mustafa T, Nima ZA, Bratton SM, Casciano D, Dervishi E, Radominska-Pandya A, Biris AS. Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells. J Appl Toxicol. 2014 Nov; 34(11):1188-99.
    View in: PubMed
    Score: 0.005
  56. Seely KA, Patton AL, Moran CL, Womack ML, Prather PL, Fantegrossi WE, Radominska-Pandya A, Endres GW, Channell KB, Smith NH, McCain KR, James LP, Moran JH. Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds. Forensic Sci Int. 2013 Dec 10; 233(1-3):416-22.
    View in: PubMed
    Score: 0.005
  57. Fantegrossi WE, Moran JH, Radominska-Pandya A, Prather PL. Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to ?(9)-THC: mechanism underlying greater toxicity? Life Sci. 2014 Feb 27; 97(1):45-54.
    View in: PubMed
    Score: 0.005
  58. Patton AL, Seely KA, Chimalakonda KC, Tran JP, Trass M, Miranda A, Fantegrossi WE, Kennedy PD, Dobrowolski P, Radominska-Pandya A, McCain KR, James LP, Endres GW, Moran JH. Targeted metabolomic approach for assessing human synthetic cannabinoid exposure and pharmacology. Anal Chem. 2013 Oct 01; 85(19):9390-9.
    View in: PubMed
    Score: 0.005
  59. Patton AL, Chimalakonda KC, Moran CL, McCain KR, Radominska-Pandya A, James LP, Kokes C, Moran JH. K2 toxicity: fatal case of psychiatric complications following AM2201 exposure. J Forensic Sci. 2013 Nov; 58(6):1676-80.
    View in: PubMed
    Score: 0.005
  60. Chimalakonda KC, James LP, Radominska-Pandya A, Moran JH. Sulfaphenazole and a-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice. Drug Metab Lett. 2013 Mar; 7(1):34-8.
    View in: PubMed
    Score: 0.005
  61. Pawlowska M, Chu R, Fedejko-Kap B, Augustin E, Mazerska Z, Radominska-Pandya A, Chambers TC. Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use. Drug Metab Dispos. 2013 Feb; 41(2):414-21.
    View in: PubMed
    Score: 0.004
  62. Chimalakonda KC, Seely KA, Bratton SM, Brents LK, Moran CL, Endres GW, James LP, Hollenberg PF, Prather PL, Radominska-Pandya A, Moran JH. Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands. Drug Metab Dispos. 2012 Nov; 40(11):2174-84.
    View in: PubMed
    Score: 0.004
  63. Fedejko-Kap B, Bratton SM, Finel M, Radominska-Pandya A, Mazerska Z. Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10. Drug Metab Dispos. 2012 Sep; 40(9):1736-43.
    View in: PubMed
    Score: 0.004
  64. Seely KA, Brents LK, Radominska-Pandya A, Endres GW, Keyes GS, Moran JH, Prather PL. A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. Chem Res Toxicol. 2012 Apr 16; 25(4):825-7.
    View in: PubMed
    Score: 0.004
  65. Fedejko-Kap B, Niemira M, Radominska-Pandya A, Mazerska Z. Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells. Xenobiotica. 2011 Dec; 41(12):1044-55.
    View in: PubMed
    Score: 0.004
  66. H?glund C, Sneitz N, Radominska-Pandya A, Laakonen L, Finel M. Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens. Steroids. 2011 Dec 11; 76(13):1465-73.
    View in: PubMed
    Score: 0.004
  67. Chimalakonda KC, Moran CL, Kennedy PD, Endres GW, Uzieblo A, Dobrowolski PJ, Fifer EK, Lapoint J, Nelson LS, Hoffman RS, James LP, Radominska-Pandya A, Moran JH. Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine. Anal Chem. 2011 Aug 15; 83(16):6381-8.
    View in: PubMed
    Score: 0.004
  68. Karmakar A, Bratton SM, Dervishi E, Ghosh A, Mahmood M, Xu Y, Saeed LM, Mustafa T, Casciano D, Radominska-Pandya A, Biris AS. Ethylenediamine functionalized-single-walled nanotube (f-SWNT)-assisted in vitro delivery of the oncogene suppressor p53 gene to breast cancer MCF-7 cells. Int J Nanomedicine. 2011; 6:1045-55.
    View in: PubMed
    Score: 0.004
  69. Moran CL, Le VH, Chimalakonda KC, Smedley AL, Lackey FD, Owen SN, Kennedy PD, Endres GW, Ciske FL, Kramer JB, Kornilov AM, Bratton LD, Dobrowolski PJ, Wessinger WD, Fantegrossi WE, Prather PL, James LP, Radominska-Pandya A, Moran JH. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. Anal Chem. 2011 Jun 01; 83(11):4228-36.
    View in: PubMed
    Score: 0.004
  70. Miller GP, Jones DR, Sullivan SZ, Mazur A, Owen SN, Mitchell NC, Radominska-Pandya A, Moran JH. Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans. Chem Res Toxicol. 2009 Jul; 22(7):1239-45.
    View in: PubMed
    Score: 0.003
  71. Mazur A, Lichti CF, Prather PL, Zielinska AK, Bratton SM, Gallus-Zawada A, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids. Drug Metab Dispos. 2009 Jul; 37(7):1496-504.
    View in: PubMed
    Score: 0.003
  72. It?aho K, Court MH, Uutela P, Kostiainen R, Radominska-Pandya A, Finel M. Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. Drug Metab Dispos. 2009 Apr; 37(4):768-75.
    View in: PubMed
    Score: 0.003
  73. Zielinska A, Lichti CF, Bratton S, Mitchell NC, Gallus-Zawada A, Le VH, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther. 2008 Jan; 324(1):139-48.
    View in: PubMed
    Score: 0.003
  74. Miley MJ, Zielinska AK, Keenan JE, Bratton SM, Radominska-Pandya A, Redinbo MR. Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7. J Mol Biol. 2007 Jun 01; 369(2):498-511.
    View in: PubMed
    Score: 0.003
  75. Sabolovic N, Humbert AC, Radominska-Pandya A, Magdalou J. Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells. Biopharm Drug Dispos. 2006 May; 27(4):181-9.
    View in: PubMed
    Score: 0.003
  76. Ronis MJ, Little JM, Barone GW, Chen G, Radominska-Pandya A, Badger TM. Sulfation of the isoflavones genistein and daidzein in human and rat liver and gastrointestinal tract. J Med Food. 2006; 9(3):348-55.
    View in: PubMed
    Score: 0.003
  77. Sabolovic N, Heydel JM, Li X, Little JM, Humbert AC, Radominska-Pandya A, Magdalou J. Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract. Biochim Biophys Acta. 2004 Nov 18; 1675(1-3):120-9.
    View in: PubMed
    Score: 0.003
  78. Xie W, Uppal H, Saini SP, Mu Y, Little JM, Radominska-Pandya A, Zemaitis MA. Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism. Drug Discov Today. 2004 May 15; 9(10):442-9.
    View in: PubMed
    Score: 0.002
  79. Mehta KD, Radominska-Pandya A, Kapoor GS, Dave B, Atkins BA. Critical role of diacylglycerol- and phospholipid-regulated protein kinase C epsilon in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol. Mol Cell Biol. 2002 Jun; 22(11):3783-93.
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  80. Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ, Evans RM. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3375-80.
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  81. Jude AR, Little JM, Freeman JP, Evans JE, Radominska-Pandya A, Grant DF. Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases. Arch Biochem Biophys. 2000 Aug 15; 380(2):294-302.
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  82. Cheng Z, Radominska-Pandya A, Tephly TR. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10. Drug Metab Dispos. 1999 Oct; 27(10):1165-70.
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  85. Cheng Z, Radominska-Pandya A, Tephly TR. Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8. Arch Biochem Biophys. 1998 Aug 15; 356(2):301-5.
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  86. Gardos G, Cole JO. Maintenance antipsychotic therapy: is the cure worse than the disease? Am J Psychiatry. 1976 Jan; 133(1):32-6.
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Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.