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Connection

Robert Reis to Humans

This is a "connection" page, showing publications Robert Reis has written about Humans.

 
Connection Strength
 
 
 
0.445
 
  1. Ganne A, Balasubramaniam M, Ayyadevara H, Kiaei L, Shmookler Reis RJ, Varughese KI, Kiaei M. In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration. Sci Rep. 2023 02 06; 13(1):2096.
    View in: PubMed
    Score: 0.018
  2. Ganne A, Balasubramaniam M, Mainali N, Atluri P, Shmookler Reis RJ, Ayyadevara S. Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases. Int J Mol Sci. 2022 Dec 07; 23(24).
    View in: PubMed
    Score: 0.018
  3. Alagpulinsa DA, Toribio MP, Alhallak I, Shmookler Reis RJ. Advances in understanding the molecular basis of clonal hematopoiesis. Trends Mol Med. 2022 05; 28(5):360-377.
    View in: PubMed
    Score: 0.017
  4. Nedosekin DA, Chen T, Ayyadevara S, Zharov VP, Shmookler Reis RJ. Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease. Sci Rep. 2021 10 05; 11(1):19732.
    View in: PubMed
    Score: 0.017
  5. Ayyadevara S, Ganne A, Balasubramaniam M, Shmookler Reis RJ. Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration. Metab Brain Dis. 2022 01; 37(1):147-152.
    View in: PubMed
    Score: 0.016
  6. Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. Bioorg Med Chem. 2021 09 01; 45:116311.
    View in: PubMed
    Score: 0.016
  7. Shmookler Reis RJ, Atluri R, Balasubramaniam M, Johnson J, Ganne A, Ayyadevara S. "Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation. Aging Cell. 2021 05; 20(5):e13326.
    View in: PubMed
    Score: 0.016
  8. Balasubramaniam M, Mainali N, Bowroju SK, Atluri P, Penthala NR, Ayyadevera S, Crooks PA, Shmookler Reis RJ. Structural modeling of GSK3? implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs. Sci Rep. 2020 10 27; 10(1):18326.
    View in: PubMed
    Score: 0.016
  9. Bowroju SK, Mainali N, Ayyadevara S, Penthala NR, Krishnamachari S, Kakraba S, Shmookler Reis RJ, Crooks PA. Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of A? Self-Aggregation and Metal Chelation-Induced A? Aggregation. Molecules. 2020 08 08; 25(16).
    View in: PubMed
    Score: 0.015
  10. Alagpulinsa DA, Szalat RE, Poznansky MC, Shmookler Reis RJ. Genomic Instability in Multiple Myeloma. Trends Cancer. 2020 10; 6(10):858-873.
    View in: PubMed
    Score: 0.015
  11. Ayyadevara S, Ganne A, Hendrix RD, Balasubramaniam M, Shmookler Reis RJ, Barger SW. Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'. J Neurosci Methods. 2019 05 01; 319:40-46.
    View in: PubMed
    Score: 0.014
  12. Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ. Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2. Sci Rep. 2018 10 05; 8(1):14891.
    View in: PubMed
    Score: 0.014
  13. Kiaei M, Balasubramaniam M, Govind Kumar V, Shmookler Reis RJ, Moradi M, Varughese KI. ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation. Sci Rep. 2018 08 30; 8(1):13102.
    View in: PubMed
    Score: 0.013
  14. Parcon PA, Balasubramaniam M, Ayyadevara S, Jones RA, Liu L, Shmookler Reis RJ, Barger SW, Mrak RE, Griffin WST. Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs. Alzheimers Dement. 2018 02; 14(2):230-242.
    View in: PubMed
    Score: 0.013
  15. Balasubramaniam M, Shmookler Reis RJ, Ayyadevara S, Wang X, Ganne A, Khaidakov M. Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase. Mech Ageing Dev. 2017 09; 166:55-63.
    View in: PubMed
    Score: 0.012
  16. Ayyadevara S, Balasubramaniam M, Kakraba S, Alla R, Mehta JL, Shmookler Reis RJ. Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation. Antioxid Redox Signal. 2017 Dec 10; 27(17):1383-1396.
    View in: PubMed
    Score: 0.012
  17. Ayyadevara S, Balasubramaniam M, Suri P, Mackintosh SG, Tackett AJ, Sullivan DH, Shmookler Reis RJ, Dennis RA. Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans. Aging (Albany NY). 2016 12 15; 8(12):3486-3497.
    View in: PubMed
    Score: 0.012
  18. Ayyadevara S, Balasubramaniam M, Parcon PA, Barger SW, Griffin WS, Alla R, Tackett AJ, Mackintosh SG, Petricoin E, Zhou W, Shmookler Reis RJ. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell. 2016 10; 15(5):924-39.
    View in: PubMed
    Score: 0.012
  19. Alagpulinsa DA, Ayyadevara S, Yaccoby S, Shmookler Reis RJ. A Cyclin-Dependent Kinase Inhibitor, Dinaciclib, Impairs Homologous Recombination and Sensitizes Multiple Myeloma Cells to PARP Inhibition. Mol Cancer Ther. 2016 Feb; 15(2):241-50.
    View in: PubMed
    Score: 0.011
  20. Alagpulinsa DA, Yaccoby S, Ayyadevara S, Shmookler Reis RJ. A peptide nucleic acid targeting nuclear RAD51 sensitizes multiple myeloma cells to melphalan treatment. Cancer Biol Ther. 2015; 16(6):976-86.
    View in: PubMed
    Score: 0.011
  21. Wuttke D, Connor R, Vora C, Craig T, Li Y, Wood S, Vasieva O, Shmookler Reis R, Tang F, de Magalh?es JP. Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes. PLoS Genet. 2012; 8(8):e1002834.
    View in: PubMed
    Score: 0.009
  22. Nedosekin DA, Galanzha EI, Ayyadevara S, Shmookler Reis RJ, Zharov VP. Photothermal confocal spectromicroscopy of multiple cellular chromophores and fluorophores. Biophys J. 2012 Feb 08; 102(3):672-81.
    View in: PubMed
    Score: 0.009
  23. Pal J, Bertheau R, Buon L, Qazi A, Batchu RB, Bandyopadhyay S, Ali-Fehmi R, Beer DG, Weaver DW, Shmookler Reis RJ, Goyal RK, Huang Q, Munshi NC, Shammas MA. Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome. Oncogene. 2011 Aug 18; 30(33):3585-98.
    View in: PubMed
    Score: 0.008
  24. Shmookler Reis RJ, Bharill P, Tazearslan C, Ayyadevara S. Extreme-longevity mutations orchestrate silencing of multiple signaling pathways. Biochim Biophys Acta. 2009 Oct; 1790(10):1075-83.
    View in: PubMed
    Score: 0.007
  25. Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC. Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Blood. 2009 Mar 05; 113(10):2290-7.
    View in: PubMed
    Score: 0.007
  26. Szumska D, Benes H, Kang P, Weinstein RS, Jilka RL, Manolagas SC, Shmookler Reis RJ. A novel locus on the X chromosome regulates post-maturity bone density changes in mice. Bone. 2007 Mar; 40(3):758-66.
    View in: PubMed
    Score: 0.006
  27. Shmookler Reis RJ, Kang P, Ayyadevara S. Quantitative trait loci define genes and pathways underlying genetic variation in longevity. Exp Gerontol. 2006 Oct; 41(10):1046-54.
    View in: PubMed
    Score: 0.006
  28. Ayyadevara S, Mercanti F, Wang X, Mackintosh SG, Tackett AJ, Prayaga SV, Romeo F, Shmookler Reis RJ, Mehta JL. Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles. Hypertension. 2016 May; 67(5):1006-13.
    View in: PubMed
    Score: 0.006
  29. Khaidakov M, Shmookler Reis RJ. Possibility of selection against mtDNA mutations in tumors. Mol Cancer. 2005 Sep 13; 4:36.
    View in: PubMed
    Score: 0.005
  30. McEwen JE, Zimniak P, Mehta JL, Shmookler Reis RJ. Molecular pathology of aging and its implications for senescent coronary atherosclerosis. Curr Opin Cardiol. 2005 Sep; 20(5):399-406.
    View in: PubMed
    Score: 0.005
  31. Shammas MA, Shmookler Reis RJ, Li C, Koley H, Hurley LH, Anderson KC, Munshi NC. Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma. Clin Cancer Res. 2004 Jan 15; 10(2):770-6.
    View in: PubMed
    Score: 0.005
  32. Shammas MA, Shmookler Reis RJ, Akiyama M, Koley H, Chauhan D, Hideshima T, Goyal RK, Hurley LH, Anderson KC, Munshi NC. Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma. Mol Cancer Ther. 2003 Sep; 2(9):825-33.
    View in: PubMed
    Score: 0.005
  33. Shmookler Reis RJ, Ebert RH. Animal models for discovery and assessment of genetic determinants of osteoporosis. Osteoporos Int. 2003 Sep; 14 Suppl 5:S100-6.
    View in: PubMed
    Score: 0.005
  34. Anisimov VN, Bartke A, Barzilai N, Batin MA, Blagosklonny MV, Brown-Borg H, Budovskaya Y, Campisi J, Friguet B, Fraifeld V, Franceschi C, Gems D, Gladyshev V, Gorbunova V, Gudkov AV, Kennedy B, Konovalenko M, Kraemer B, Moskalev A, Petropoulos I, Pasyukova E, Rattan S, Rogina B, Seluanov A, Shaposhnikov M, Shmookler Reis R, Tavernarakis N, Vijg J, Yashin A, Zimniak P. The second international conference "genetics of aging and longevity". Aging (Albany NY). 2012 May; 4(5):305-17.
    View in: PubMed
    Score: 0.004
  35. Batchu RB, Shammas MA, Wang JY, Shmookler Reis RJ, Munshi NC. Expression of AAV Rep proteins in SV40-transformed and untransformed cells: reciprocal interaction with host DNA synthesis. Intervirology. 2001; 44(5):298-305.
    View in: PubMed
    Score: 0.004
  36. Shammas MA, Simmons CG, Corey DR, Shmookler Reis RJ. Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells. Oncogene. 1999 Nov 04; 18(46):6191-200.
    View in: PubMed
    Score: 0.004
  37. Shmookler Reis RJ. Strategies and criteria for the development of molecular biomarkers of senescence. Exp Gerontol. 1988; 23(4-5):271-80.
    View in: PubMed
    Score: 0.003
  38. Xia SJ, Shammas MA, Shmookler Reis RJ. Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase. Mol Cell Biol. 1997 Dec; 17(12):7151-8.
    View in: PubMed
    Score: 0.003
  39. Li J, Ayyadevera R, Shmookler Reis RJ. Carcinogens stimulate intrachromosomal homologous recombination at an endogenous locus in human diploid fibroblasts. Mutat Res. 1997 Dec; 385(3):173-93.
    View in: PubMed
    Score: 0.003
  40. Shammas MA, Xia SJ, Shmookler Reis RJ. Induction of duplication reversion in human fibroblasts, by wild-type and mutated SV40 T antigen, covaries with the ability to induce host DNA synthesis. Genetics. 1997 Aug; 146(4):1417-28.
    View in: PubMed
    Score: 0.003
  41. Cheng RZ, Shammas MA, Li J, Shmookler Reis RJ. Expression of SV40 large T antigen stimulates reversion of a chromosomal gene duplication in human cells. Exp Cell Res. 1997 Aug 01; 234(2):300-12.
    View in: PubMed
    Score: 0.003
  42. Nikitin AG, Shmookler Reis RJ. Role of transposable elements in age-related genomic instability. Genet Res. 1997 Jun; 69(3):183-95.
    View in: PubMed
    Score: 0.003
  43. Xia SJ, Shammas MA, Shmookler Reis RJ. Reduced telomere length in ataxia-telangiectasia fibroblasts. Mutat Res. 1996 Sep 02; 364(1):1-11.
    View in: PubMed
    Score: 0.003
  44. Shmookler Reis RJ, Ebert RH. Genetics of aging: current animal models. Exp Gerontol. 1996 Jan-Apr; 31(1-2):69-81.
    View in: PubMed
    Score: 0.003
  45. Parsons CA, Mroczkowski HJ, McGuigan FE, Albagha OM, Manolagas S, Reid DM, Ralston SH, Shmookler Reis RJ. Interspecies synteny mapping identifies a quantitative trait locus for bone mineral density on human chromosome Xp22. Hum Mol Genet. 2005 Nov 01; 14(21):3141-8.
    View in: PubMed
    Score: 0.003
  46. Riabowol K, Shmookler Reis RJ, Goldstein S. Interspersed repetitive and tandemly repetitive sequences are differentially represented in extrachromosomal covalently closed circular DNA of human diploid fibroblasts. Nucleic Acids Res. 1985 Aug 12; 13(15):5563-84.
    View in: PubMed
    Score: 0.003
  47. Shammas MA, Liu X, Gavory G, Raney KD, Balasubramanian S, Shmookler Reis RJ. Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. Exp Cell Res. 2004 Apr 15; 295(1):204-14.
    View in: PubMed
    Score: 0.002
  48. Murano S, Thweatt R, Shmookler Reis RJ, Jones RA, Moerman EJ, Goldstein S. Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence. Mol Cell Biol. 1991 Aug; 11(8):3905-14.
    View in: PubMed
    Score: 0.002
  49. Thweatt R, Goldstein S, Shmookler Reis RJ. A universal primer mixture for sequence determination at the 3' ends of cDNAs. Anal Biochem. 1990 Nov 01; 190(2):314-6.
    View in: PubMed
    Score: 0.002
  50. Goldstein S, Jones RA, Hardin JW, Braunstein GD, Shmookler Reis RJ. Expression of alpha- and beta-human chorionic gonadotropin subunits in cultured human cells. In Vitro Cell Dev Biol. 1990 Sep; 26(9):857-64.
    View in: PubMed
    Score: 0.002
  51. Cheng RZ, Murano S, Kurz B, Shmookler Reis RJ. Homologous recombination is elevated in some Werner-like syndromes but not during normal in vitro or in vivo senescence of mammalian cells. Mutat Res. 1990 Sep-Nov; 237(5-6):259-69.
    View in: PubMed
    Score: 0.002
  52. Srivastava A, Shmookler Reis RJ, Goldstein S. Absence of reverse transcriptase activity in human diploid fibroblasts. Mech Ageing Dev. 1990 Feb 01; 51(2):133-8.
    View in: PubMed
    Score: 0.002
  53. Shmookler Reis RJ, Finn GK, Smith K, Goldstein S. Clonal variation in gene methylation: c-H-ras and alpha-hCG regions vary independently in human fibroblast lineages. Mutat Res. 1990 Jan; 237(1):45-57.
    View in: PubMed
    Score: 0.002
  54. Goldstein S, Murano S, Shmookler Reis RJ. Werner syndrome: a molecular genetic hypothesis. J Gerontol. 1990 Jan; 45(1):B3-8.
    View in: PubMed
    Score: 0.002
  55. Finn GK, Kurz BW, Cheng RZ, Shmookler Reis RJ. Homologous plasmid recombination is elevated in immortally transformed cells. Mol Cell Biol. 1989 Sep; 9(9):4009-17.
    View in: PubMed
    Score: 0.002
  56. Houde M, Shmookler Reis RJ, Goldstein S. Proportions of H1 histone subspecies in human fibroblasts shift during density-dependent growth arrest independent of replicative senescence. Exp Cell Res. 1989 Sep; 184(1):256-61.
    View in: PubMed
    Score: 0.002
  57. Goldstein S, Murano S, Benes H, Moerman EJ, Jones RA, Thweatt R, Shmookler Reis RJ, Howard BH. Studies on the molecular-genetic basis of replicative senescence in Werner syndrome and normal fibroblasts. Exp Gerontol. 1989; 24(5-6):461-8.
    View in: PubMed
    Score: 0.002
  58. Shmookler Reis RJ, Srivastava A, Beranek DT, Goldstein S. Human alphoid family of tandemly repeated DNA. Sequence of cloned tetrameric fragments and analysis of familial divergence. J Mol Biol. 1985 Nov 05; 186(1):31-41.
    View in: PubMed
    Score: 0.001
  59. Goldstein S, Shmookler Reis RJ. Methylation patterns in the gene for the alpha subunit of chorionic gonadotropin are inherited with variable fidelity in clonal lineages of human fibroblasts. Nucleic Acids Res. 1985 Oct 11; 13(19):7055-65.
    View in: PubMed
    Score: 0.001
  60. Srivastava A, Norris JS, Shmookler Reis RJ, Goldstein S. c-Ha-ras-1 proto-oncogene amplification and overexpression during the limited replicative life span of normal human fibroblasts. J Biol Chem. 1985 May 25; 260(10):6404-9.
    View in: PubMed
    Score: 0.001
  61. Shmookler Reis RJ, Goldstein S. Mitochondrial DNA in mortal and immortal human cells. Genome number, integrity, and methylation. J Biol Chem. 1983 Aug 10; 258(15):9078-85.
    View in: PubMed
    Score: 0.001
  62. Shmookler Reis RJ, Goldstein S. Interclonal variation in methylation patterns for expressed and non-expressed genes. Nucleic Acids Res. 1982 Jul 24; 10(14):4293-304.
    View in: PubMed
    Score: 0.001
  63. Shmookler Reis RJ, Goldstein S. Variability of DNA methylation patterns during serial passage of human diploid fibroblasts. Proc Natl Acad Sci U S A. 1982 Jul; 79(13):3949-53.
    View in: PubMed
    Score: 0.001
  64. Harley CB, Shmookler Reis RJ, Goldstein S. Loss of repetitious DNA in proliferating somatic cells may be due to unequal recombination. J Theor Biol. 1982 Jan 07; 94(1):1-12.
    View in: PubMed
    Score: 0.001
  65. Shmookler Reis RJ, Lumpkin CK, McGill JR, Riabowol KT, Goldstein S. Amplification of inter-Alu extrachromosomal DNA during cellular ageing: retraction and explanation. Nature. 1985 Jul 11-17; 316(6024):167.
    View in: PubMed
    Score: 0.001
  66. Lumpkin CK, McGill JR, Riabowol KT, Moerman EJ, Shmookler Reis RJ, Goldstein S. Extrachromosomal circular DNA and aging cells. Adv Exp Med Biol. 1985; 190:479-93.
    View in: PubMed
    Score: 0.001
  67. Goldstein S, Srivastava A, Riabowol KT, Shmookler Reis RJ. Changes in genetic organization and expression in aging cells. Basic Life Sci. 1985; 35:255-67.
    View in: PubMed
    Score: 0.001
  68. Shmookler Reis RJ, Lumpkin CK, McGill JR, Riabowol KT, Goldstein S. Extrachromosomal circular copies of an 'inter-Alu' unstable sequence in human DNA are amplified during in vitro and in vivo ageing. Nature. 1983 Feb 03; 301(5899):394-8.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.