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Connection

Stavros Manolagas to Humans

This is a "connection" page, showing publications Stavros Manolagas has written about Humans.

 
Connection Strength
 
 
 
0.496
 
  1. Ponte F, Kim HN, Warren A, Iyer S, Han L, Mannen E, Gomez-Acevedo H, Nookaew I, Almeida M, Manolagas SC. Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency. Sci Rep. 2022 06 17; 12(1):10257.
    View in: PubMed
    Score: 0.035
  2. Manolagas SC. The Quest for Osteoporosis Mechanisms and Rational Therapies: How Far We've Come, How Much Further We Need to Go. J Bone Miner Res. 2018 03; 33(3):371-385.
    View in: PubMed
    Score: 0.026
  3. Almeida M, Laurent MR, Dubois V, Claessens F, O'Brien CA, Bouillon R, Vanderschueren D, Manolagas SC. Estrogens and Androgens in Skeletal Physiology and Pathophysiology. Physiol Rev. 2017 01; 97(1):135-187.
    View in: PubMed
    Score: 0.024
  4. Carson JA, Manolagas SC. Effects of sex steroids on bones and muscles: Similarities, parallels, and putative interactions in health and disease. Bone. 2015 Nov; 80:67-78.
    View in: PubMed
    Score: 0.022
  5. Manolagas SC, Compston J, Rao S, Seeman E. A. Michael Parfitt: Enlightened Scholar and Revered Mentor: May 10, 1930-May 18, 2015. J Bone Miner Res. 2015 Aug; 30(8):1349-55.
    View in: PubMed
    Score: 0.021
  6. Manolagas SC, Kronenberg HM. Reproducibility of results in preclinical studies: a perspective from the bone field. J Bone Miner Res. 2014 Oct; 29(10):2131-40.
    View in: PubMed
    Score: 0.020
  7. Manolagas SC. Wnt signaling and osteoporosis. Maturitas. 2014 Jul; 78(3):233-7.
    View in: PubMed
    Score: 0.020
  8. Manolagas SC, O'Brien CA, Almeida M. The role of estrogen and androgen receptors in bone health and disease. Nat Rev Endocrinol. 2013 Dec; 9(12):699-712.
    View in: PubMed
    Score: 0.019
  9. Manolagas SC, Cummings SR. Skeletal aging: from bench to bed side. J Gerontol A Biol Sci Med Sci. 2013 Oct; 68(10):1195-6.
    View in: PubMed
    Score: 0.019
  10. Manolagas SC. Steroids and osteoporosis: the quest for mechanisms. J Clin Invest. 2013 May; 123(5):1919-21.
    View in: PubMed
    Score: 0.018
  11. Manolagas SC, Parfitt AM. For whom the bell tolls: distress signals from long-lived osteocytes and the pathogenesis of metabolic bone diseases. Bone. 2013 Jun; 54(2):272-8.
    View in: PubMed
    Score: 0.018
  12. Jilka RL, O'Brien CA, Bartell SM, Weinstein RS, Manolagas SC. Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms. J Bone Miner Res. 2010 Nov; 25(11):2427-37.
    View in: PubMed
    Score: 0.016
  13. Almeida M, Han L, Ambrogini E, Bartell SM, Manolagas SC. Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens. Mol Endocrinol. 2010 Oct; 24(10):2030-7.
    View in: PubMed
    Score: 0.015
  14. Almeida M, Martin-Millan M, Ambrogini E, Bradsher R, Han L, Chen XD, Roberson PK, Weinstein RS, O'Brien CA, Jilka RL, Manolagas SC. Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha. J Bone Miner Res. 2010 Apr; 25(4):769-81.
    View in: PubMed
    Score: 0.015
  15. Manolagas SC, Parfitt AM. What old means to bone. Trends Endocrinol Metab. 2010 Jun; 21(6):369-74.
    View in: PubMed
    Score: 0.015
  16. Ambrogini E, Almeida M, Martin-Millan M, Paik JH, Depinho RA, Han L, Goellner J, Weinstein RS, Jilka RL, O'Brien CA, Manolagas SC. FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice. Cell Metab. 2010 Feb 03; 11(2):136-46.
    View in: PubMed
    Score: 0.015
  17. Manolagas SC. From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr Rev. 2010 Jun; 31(3):266-300.
    View in: PubMed
    Score: 0.015
  18. Weinstein RS, Roberson PK, Manolagas SC. Giant osteoclast formation and long-term oral bisphosphonate therapy. N Engl J Med. 2009 Jan 01; 360(1):53-62.
    View in: PubMed
    Score: 0.014
  19. Jilka RL, Weinstein RS, Parfitt AM, Manolagas SC. Quantifying osteoblast and osteocyte apoptosis: challenges and rewards. J Bone Miner Res. 2007 Oct; 22(10):1492-501.
    View in: PubMed
    Score: 0.013
  20. Manolagas SC, Almeida M. Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism. Mol Endocrinol. 2007 Nov; 21(11):2605-14.
    View in: PubMed
    Score: 0.012
  21. Kousteni S, Almeida M, Han L, Bellido T, Jilka RL, Manolagas SC. Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor. Mol Cell Biol. 2007 Feb; 27(4):1516-30.
    View in: PubMed
    Score: 0.012
  22. Manolagas SC, Jilka RL, Kousteni S, Bellido T, Weinstein RS, O'Brien CA, Plotkin L, Han L. Response to Windahl et al. J Clin Invest. 2006 Nov; 116(11):2834.
    View in: PubMed
    Score: 0.012
  23. Vertino AM, Bula CM, Chen JR, Almeida M, Han L, Bellido T, Kousteni S, Norman AW, Manolagas SC. Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases. J Biol Chem. 2005 Apr 08; 280(14):14130-7.
    View in: PubMed
    Score: 0.010
  24. Manolagas SC, Kousteni S, Chen JR, Schuller M, Plotkin L, Bellido T. Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: a different perspective on the HRT dilemma. Kidney Int Suppl. 2004 Oct; (91):S41-9.
    View in: PubMed
    Score: 0.010
  25. Ijaz MT, Manolagas SC. A patient with pseudohypoparathyroidism. J Ark Med Soc. 2003 Nov; 100(5):164-6.
    View in: PubMed
    Score: 0.010
  26. Abe Y, Kofman ER, Almeida M, Ouyang Z, Ponte F, Mueller JR, Cruz-Becerra G, Sakai M, Prohaska TA, Spann NJ, Resende-Coelho A, Seidman JS, Stender JD, Taylor H, Fan W, Link VM, Cobo I, Schlachetzki JCM, Hamakubo T, Jepsen K, Sakai J, Downes M, Evans RM, Yeo GW, Kadonaga JT, Manolagas SC, Rosenfeld MG, Glass CK. RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1?- and RNA-dependent co-activator of osteoclast gene expression. Mol Cell. 2023 10 05; 83(19):3421-3437.e11.
    View in: PubMed
    Score: 0.009
  27. Kousteni S, Han L, Chen JR, Almeida M, Plotkin LI, Bellido T, Manolagas SC. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J Clin Invest. 2003 Jun; 111(11):1651-64.
    View in: PubMed
    Score: 0.009
  28. Manolagas SC, Kousteni S, Jilka RL. Sex steroids and bone. Recent Prog Horm Res. 2002; 57:385-409.
    View in: PubMed
    Score: 0.008
  29. Manolagas SC, Kousteni S. Perspective: nonreproductive sites of action of reproductive hormones. Endocrinology. 2001 Jun; 142(6):2200-4.
    View in: PubMed
    Score: 0.008
  30. Onal M, Xiong J, Chen X, Thostenson JD, Almeida M, Manolagas SC, O'Brien CA. Receptor activator of nuclear factor ?B ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss. J Biol Chem. 2012 Aug 24; 287(35):29851-60.
    View in: PubMed
    Score: 0.004
  31. Andrade AC, Baron J, Manolagas SC, Shaw NJ, Rappold GA, Donaldson MD, Gault EJ, S?vendahl L. Hormones and genes of importance in bone physiology and their influence on bone mineralization and growth in Turner syndrome. Horm Res Paediatr. 2010; 73(3):161-5.
    View in: PubMed
    Score: 0.004
  32. Plotkin LI, Lezcano V, Thostenson J, Weinstein RS, Manolagas SC, Bellido T. Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo. J Bone Miner Res. 2008 Nov; 23(11):1712-21.
    View in: PubMed
    Score: 0.003
  33. O'Brien CA, Plotkin LI, Galli C, Goellner JJ, Gortazar AR, Allen MR, Robling AG, Bouxsein M, Schipani E, Turner CH, Jilka RL, Weinstein RS, Manolagas SC, Bellido T. Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One. 2008 Aug 13; 3(8):e2942.
    View in: PubMed
    Score: 0.003
  34. Aguirre JI, Plotkin LI, Gortazar AR, Millan MM, O'Brien CA, Manolagas SC, Bellido T. A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction. J Biol Chem. 2007 Aug 31; 282(35):25501-8.
    View in: PubMed
    Score: 0.003
  35. Szumska D, Benes H, Kang P, Weinstein RS, Jilka RL, Manolagas SC, Shmookler Reis RJ. A novel locus on the X chromosome regulates post-maturity bone density changes in mice. Bone. 2007 Mar; 40(3):758-66.
    View in: PubMed
    Score: 0.003
  36. Fu Q, Manolagas SC, O'Brien CA. Parathyroid hormone controls receptor activator of NF-kappaB ligand gene expression via a distant transcriptional enhancer. Mol Cell Biol. 2006 Sep; 26(17):6453-68.
    View in: PubMed
    Score: 0.003
  37. Plotkin LI, Manolagas SC, Bellido T. Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs. Bone. 2006 Sep; 39(3):443-52.
    View in: PubMed
    Score: 0.003
  38. Parsons CA, Mroczkowski HJ, McGuigan FE, Albagha OM, Manolagas S, Reid DM, Ralston SH, Shmookler Reis RJ. Interspecies synteny mapping identifies a quantitative trait locus for bone mineral density on human chromosome Xp22. Hum Mol Genet. 2005 Nov 01; 14(21):3141-8.
    View in: PubMed
    Score: 0.003
  39. Bellido T, Ali AA, Plotkin LI, Fu Q, Gubrij I, Roberson PK, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism. J Biol Chem. 2003 Dec 12; 278(50):50259-72.
    View in: PubMed
    Score: 0.002
  40. Fu Q, Jilka RL, Manolagas SC, O'Brien CA. Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein. J Biol Chem. 2002 Dec 13; 277(50):48868-75.
    View in: PubMed
    Score: 0.002
  41. Plotkin LI, Manolagas SC, Bellido T. Transduction of cell survival signals by connexin-43 hemichannels. J Biol Chem. 2002 Mar 08; 277(10):8648-57.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.