Nalini Bora
Title | Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Ophthalmology, College of Medicine |
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Division | Ophthalmology Faculty |
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Address | J317 Jones Eye Institute 4105 Outpatient Circle Mail Slot # 523 Little Rock AR 72205
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Phone | 501-686-5150 |
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vCard | Download vCard |
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Title | Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Genetics, College of Medicine |
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Title | Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Microbiology And Immunology, College of Medicine |
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Research R01EY022333 (BORA, NALINI S.)Dec 1, 2012 - Nov 30, 2015 NIH Uveitogenic Epitope(s) and Idiopathic Anterior Uveitis Role: Principal Investigator |
| R44EY018017 (BORA, NALINI S)May 12, 2010 - May 11, 2011 NIH/Nat. Eye Institute MASP-2 Therapy for Macular Degeneration NIH Grant # 2R44EY018017-02A1 Role: Principal Investigator |
| Factor H (BORA, NALINI S)Sep 2, 2009 - Sep 1, 2012 Baxter Healthcare Corporation Evaluation of Human Factor H in Murine CNV Model Role: Principal Investigator |
| FactorH (BORA, NALINI S)Sep 2, 2009 - Sep 1, 2012 Baxter Healthcare Corporation Evaluation of Human Factor H in Murine CNV Model Role: Principal Investigator |
| R01EY018812 (BORA, NALINI S.)Jul 1, 2009 - Jun 30, 2013 NIH Complement System and Idiopathic Anterior Uveitis Role: Principal Investigator |
| MASP-2 (BORA, NALINI S)Oct 31, 2008 - Oct 30, 2009 Omeros Corporation Assessment of Laser -Induced CNV in Rats treated with MASP-2 Blocking MoAbs Role: Principal Investigator |
| R01EY016205 (BORA, NALINI S.)Feb 1, 2005 - Jan 31, 2011 NIH Idiopathic Anterior Uveitis and Type I Collagen Role: Principal Investigator |
| R01EY014623 (BORA, PURAN S)Aug 1, 2003 - Jun 30, 2013 NIH Complement System and Choroidal Neovascularization Role: Co-Investigator |
| R01EY013335 (BORA, NALINI S.)Aug 1, 2001 - Jul 31, 2007 NIH Complement System and the Eye Role: Principal Investigator |
| R01EY009730 (BORA, NALINI S.)Aug 1, 1994 - Mar 31, 2002 NIH ETIOPATHOGENESIS OF UVEITIS Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Bora NS, Bora PS. Genetic Insights into Age-Related Macular Degeneration. Biomedicines. 2024 Jul 04; 12(7). PMID: 39062052.
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Choubey M, Tirumalasetty MB, Bora NS, Bora PS. Linking Adiponectin and Its Receptors to Age-Related Macular Degeneration (AMD). Biomedicines. 2023 Nov 14; 11(11). PMID: 38002042.
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Logan C, Lyzogubov V, Bora N, Bora P. Role of Adiponectin Peptide I (APNp1) in Age-Related Macular Degeneration. Biomolecules. 2022 09 03; 12(9). PMID: 36139070.
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Park A, Hardin JS, Bora NS, Morshedi RG. Effects of Lidocaine on Mitomycin C Cytotoxicity. Ophthalmol Glaucoma. 2021 May-Jun; 4(3):330-335. PMID: 33080409.
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Lyzogubov V, Dasso M, Bora N, Bora PS. Role of thalidomide, senicapoc, and sodium butyrate in choroidal neovascularization. Biochem Biophys Res Commun. 2020 09 17; 530(2):367-373. PMID: 32800337.
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Matta B, Bora PS, Neuhouser AJ, Bora NS. Inhibitory role of transforming growth factor ?2 in experimental autoimmune anterior uveitis. Graefes Arch Clin Exp Ophthalmol. 2019 May; 257(5):953-960. PMID: 30719689.
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Lyzogubov VV, Bora PS, Wu X, Horn LE, de Roque R, Rudolf XV, Atkinson JP, Bora NS. The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration-Like Phenotype. Am J Pathol. 2016 08; 186(8):2088-2104. PMID: 27295359.
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Goyal S, Lyzogubov VV, Ali O, Bora PS, Bora NS, Uwaydat SH. Effect of aspirin on models of retinal pigment epithelium pathology. Clin Exp Ophthalmol. 2016 Sep; 44(7):610-617. PMID: 26861462.
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Lyzogubov VV, Bora NS, Tytarenko RG, Bora PS. Polyethylene glycol induced mouse model of retinal degeneration. Exp Eye Res. 2014 Oct; 127:143-52. PMID: 25088354.
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Bora NS, Matta B, Lyzogubov VV, Bora PS. Relationship between the complement system, risk factors and prediction models in age-related macular degeneration. Mol Immunol. 2015 Feb; 63(2):176-83. PMID: 25074023.
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Lyzogubov V, Wu X, Jha P, Tytarenko R, Triebwasser M, Kolar G, Bertram P, Bora PS, Atkinson JP, Bora NS. Complement regulatory protein CD46 protects against choroidal neovascularization in mice. Am J Pathol. 2014 Sep; 184(9):2537-48. PMID: 25019227.
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Khaidakov M, Mitra S, Wang X, Ding Z, Bora N, Lyzogubov V, Romeo F, Schichman SA, Mehta JL. Large impact of low concentration oxidized LDL on angiogenic potential of human endothelial cells: a microarray study. PLoS One. 2012; 7(10):e47421. PMID: 23115646.
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Davis SJ, Lyzogubov VV, Tytarenko RG, Safar AN, Bora NS, Bora PS. The effect of nicotine on anti-vascular endothelial growth factor therapy in a mouse model of neovascular age-related macular degeneration. Retina. 2012 Jun; 32(6):1171-80. PMID: 22088983.
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Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS. Inhibitory role of adiponectin peptide I on rat choroidal neovascularization. Biochim Biophys Acta. 2012 Aug; 1823(8):1264-72. PMID: 22633972.
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Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS. Inhibitory role of adiponectin peptide 1 on rat model of choroidal neovascularization. Biochim Biophys Acta. 2012; 1823(3):1264-1272.
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Davis SJ, Lyzogubov VV, Tytarenko RG, Safar AN, Bora NS, Bora PS. The Effect of Nicotine on the Anti-Vascular Endothelial Growth Factor Therapy in a Mouse Model of Neovascular Age-Related Macular Degeneration. Retina. 2012; 48:1171-1180.
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Uwaydat S, Jha P, Tytarenko R, Brown H, Wiggins M, Bora PS, Bora NS. The use of topical honey in the treatment of corneal abrasions and endotoxin-induced keratitis in an animal model. Curr Eye Res. 2011 Sep; 36(9):787-96. PMID: 21812661.
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Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS. Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization. J Biol Chem. 2011 Jun 10; 286(23):20991-1001. PMID: 21515678.
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Lyzogubov VV, Tytarenko RG, Liu J, Bora NS, Bora PS. Polyethylene glycol (PEG)-induced mouse model of choroidal neovascularization. J Biol Chem. 2011 May 06; 286(18):16229-37. PMID: 21454496.
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Manickam B, Jha P, Matta B, Liu J, Bora PS, Bora NS. Inhibition of complement alternative pathway suppresses experimental autoimmune anterior uveitis by modulating T cell responses. J Biol Chem. 2011 Mar 11; 286(10):8472-8480. PMID: 21216963.
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Jha P, Banda H, Tytarenko RG, Bora PS, Bora NS. Cmplement Mediated Apoptosis Leads to the Loss of Retinal Ganglion Cells in Animal Model of Galucoma. Molecular Immunology. 2011; 48:2151-2158.
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Uwaydat S, Jha P, Tytarenko RG, Brown H, Wiggins M, Bora PS, Bora NS. The use of topical honey in the treatment of corneal abrasions and endotoxin induced kereatitis in an animal model. Curr Eye Res. 2011; 36(9):787-796.
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Manickam B, Jha P, Matta B, Bora PS, Bora NS. Inhibition of Complement Alternative Pathway Suppresses Experimental Autoimmune Anterior Uveitis (EAAU) by Modulating T Cell Responses. J of Biological Chemistry. 2011; 286:8472-8480.
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Manickam B, Jha P, Hepburn NJ, Morgan BP, Harris CL, Bora PS, Bora NS. Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU). Mol Immunol. 2010 Nov-Dec; 48(1-3):231-9. PMID: 20843553.
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Lyzogubov VV, Tytarenko RG, Jha P, Liu J, Bora NS, Bora PS. Role of ocular complement factor H in a murine model of choroidal neovascularization. Am J Pathol. 2010 Oct; 177(4):1870-80. PMID: 20813971.
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Bora NS, Jha P, Lyzogubov VV, Kaliappan S, Liu J, Tytarenko RG, Fraser DA, Morgan BP, Bora PS. Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice. J Biol Chem. 2010 Oct 29; 285(44):33826-33. PMID: 20736175.
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Jha P, Lyzogubov VV, Kaliappan S, Liu J, Tytarenko RG, Fraser DH, Morgan BP, Bora PS, Bora NS. Recombinant Membrane Targeted Form of CD59 Inhibits the Growh of Choroidal Neovascular Complex in Mice. J Biological Chemistry. 2010; 285(44):33826-33833.
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Jha, P, Bora, P.S., Bora NS. Role of Complement in Ocular immune response. Encyclopedia of the Eye. 2010; 4:160-164.
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Matta, B, Jha, P, Bora, P.S., Bora NS. Antigen specific tolerance inhibits autoimmune unveitis in pre-sensitized animals via deletion and CD4 CD25 T regulatory cells. Immunology & Cell Biology. 2010; 88:187-196.
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Matta B, Jha P, Bora PS, Bora NS. Antigen-specific tolerance inhibits autoimmune uveitis in pre-sensitized animals by deletion and CD4+CD25+ T-regulatory cells. Immunol Cell Biol. 2010 Feb; 88(2):187-96. PMID: 19884905.
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Jha P, Manickam B, Matta B, Bora PS, Bora NS. Proteolytic cleavage of type I collagen generates an autoantigen in autoimmune uveitis. J Biol Chem. 2009 Nov 06; 284(45):31401-11. PMID: 19755419.
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Lyzogubov VV, Tytarenko RG, Thotakura S, Viswanathan T, Bora NS, Bora PS. Inhibition of new vessel growth in mouse model of laser-induced choroidal neovascularization by adiponectin peptide II. Cell Biol Int. 2009 Jul; 33(7):765-71. PMID: 19422927.
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Davis, S.J., Lyzogubov, V.V., Tytarenko, R. G., Safar, A.N., Bora NS, Bora, P. S. ARVO; May 1-6, 2010;. ARVO. 2009.
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Tytarenko, R. G., Lyzogubov, V.V., Jha, P, Liu, J, Bora NS, Bora, P.S. Role of Ocular Complement Factor H in Animal Model of Choroidal Neovascularization. ARVO. 2009.
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Jha, P., Matta, B., Tytarenko, R. G., Bora, P. S., Bora NS. Role of Complement in the Protection of Retinal Ganglion Cells in Chronic Ocular Hypertension Model of Glaucoma. ARVO. 2009.
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Davis. S.J., Lyzogubov, V.V., Tytarenko, R.G., Bora NS, Bora, P.S. Nicotine receptor antagonists and the treatment of neovascular age-related macular degeneration. AOS. 2009.
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Jha, P, Manickam, B, Matta, B, Bora, P. S., Bora NS. Proteolytic Cleavage of Type I Collagen Generates and Autoantigen in Autoimmune Uveitis. J of Biological Chemistry. 2009; 284:31401-31411.
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Liu, J, Jha, P., Lyzogubov, P. S., Bora, P.S., Bora NS. Recombinant Membrane-Targeted CD59 Inhibits the Growth of Choroidal Neovascular Complex in Murine Model of Laser-Induced Choroidal Neovascularization (CNV). ARVO. 2009.
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Lyzogubov, V.V., Tytarenko, R. G., Bora, P.S., Bora NS. Relationship Between Complement Actvation and Choroidal Neovascularization in Type II Diabetes. ARVO. 2009.
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Bora NS. International Press Coverage. Interviewed by science and technology magazine "Notes on Engineering Reseaarch and Develpment". 2009.
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Matta, B., Jha, P, Bora, P.S., Bora NS. Role of T Effector and CD4+CD25+FoxP3+T Regulatory Cells in Idiopathic Anterior Uveitis. ARVO. 2009.
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Matta B, Jha P, Bora PS, Bora NS. Tolerance to melanin-associated antigen in autoimmune uveitis is mediated by CD4+CD25+ T-regulatory cells. Am J Pathol. 2008 Nov; 173(5):1440-54. PMID: 18832572.
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Kaliappan S, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS. Alcohol and nicotine consumption exacerbates choroidal neovascularization by modulating the regulation of complement system. FEBS Lett. 2008 Oct 15; 582(23-24):3451-8. PMID: 18789935.
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Bora NS, Jha P, Bora PS. The role of complement in ocular pathology. Semin Immunopathol. 2008 Apr; 30(2):85-95. PMID: 18299835.
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Chang JY, Bora PS, Bora NS. Prevention of Oxidative Stress-Induced Retinal Pigment Epithelial Cell Death by the PPARgamma Agonists, 15-Deoxy-Delta 12, 14-Prostaglandin J(2). PPAR Res. 2008; 2008:720163. PMID: 18382621.
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Chang JY, Bora PS, Bora NS. Prevention of oxidative stress induced RPE cell death by PPARy agonist, 15-deoxy-delta 12, 14-Prostaglandin J2. (Review Article). PPAR Research. 2008.
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Bora NS, Jha P, Bora PS. The role of complement in ocular pathology (Review Article). Seminars in Immunopathology. 2008; 30:80-95.
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S Kaliappan, P Jha, V V Lyzogubov, R Tyteranko, N Bora, P Bora. Alcohol and Nicotine Consumption Exacerbates Choroidal Neovascularization by. FEBS Letters. 2008; 582:3452-3458.
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Jha P, Matta B, Lyzogubov V, Tytarenko R, Bora PS, Bora NS. Crucial role of apoptosis in the resolution of experimental autoimmune anterior uveitis. Invest Ophthalmol Vis Sci. 2007 Nov; 48(11):5091-100. PMID: 17962461.
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Jha P, Bora PS, Bora NS. The role of complement system in ocular diseases including uveitis and macular degeneration. Mol Immunol. 2007 Sep; 44(16):3901-8. PMID: 17768108.
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Bora PS, Kaliappan S, Lyzogubov VV, Tytarenko RG, Thotakura S, Viswanathan T, Bora NS. Expression of adiponectin in choroidal tissue and inhibition of laser induced choroidal neovascularization by adiponectin. FEBS Lett. 2007 May 15; 581(10):1977-82. PMID: 17466298.
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Bora NS, Kaliappan S, Jha P, Xu Q, Sivasankar B, Harris CL, Morgan BP, Bora PS. CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration. J Immunol. 2007 Feb 01; 178(3):1783-90. PMID: 17237428.
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Bora NS, Kaplan HJ. Intraocular diseases - anterior uveitis. Chem Immunol Allergy. 2007; 92:213-220. PMID: 17264497.
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Sohn JH, Bora PS, Jha P, Tezel TH, Kaplan HJ, Bora NS. Complement, innate immunity and ocular disease. Chem Immunol Allergy. 2007; 92:105-114. PMID: 17264487.
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Sohn JH, Bora PS, Jha P, Tezel TH, Kaplan HJ, Bora NS. Immune Response and the Eye. Complement, Innate Immunity and Ocular Disease. 2007.
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Bora NS, Kaplan HJ. Immune Response And The Eye. Intraocular Diseases-Anterior Uveitis. 2007.
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Jha P, Bora PS, Bora NS. The role of complement system in ocular diseases including uveitis and macular degeneration (Review Article). Molecular Immunology. 2007; 44:3901-3908.
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Bora NS, Kaliappan S, Jha P, Xu Q, Sohn JH, Dhaulakhandi DB, Kaplan HJ, Bora PS. Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H. J Immunol. 2006 Aug 01; 177(3):1872-8. PMID: 16849499.
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Jha P, Sohn JH, Xu Q, Wang Y, Kaplan HJ, Bora PS, Bora NS. Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU). J Immunol. 2006 Jun 15; 176(12):7221-31. PMID: 16751365.
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Bora PS, Kaliappan S, Xu Q, Kumar S, Wang Y, Kaplan HJ, Bora NS. Alcohol linked to enhanced angiogenesis in rat model of choroidal neovascularization. FEBS J. 2006 Apr; 273(7):1403-14. PMID: 16689928.
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Jha P, Sohn JH, Xu Q, Nishihori H, Wang Y, Nishihori S, Manickam B, Kaplan HJ, Bora PS, Bora NS. The complement system plays a critical role in the development of experimental autoimmune anterior uveitis. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1030-8. PMID: 16505038.
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Jha P, Bora PS, Sohn JH, Kaplan HJ, Bora NS. Complement system and the eye. Adv Exp Med Biol. 2006; 586:53-62. PMID: 16893064.
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Bora NS, Sohn JH, Bora PS, Kaplan HJ, Kulkarni P. Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU). Ocul Immunol Inflamm. 2005 Apr-Jun; 13(2-3):183-9. PMID: 16019677.
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Bora PS, Sohn JH, Cruz JM, Jha P, Nishihori H, Wang Y, Kaliappan S, Kaplan HJ, Bora NS. Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization. J Immunol. 2005 Jan 01; 174(1):491-7. PMID: 15611275.
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Tezel TH, Bora NS, Kaplan HJ. Pathogenesis of age-related macular degeneration. Trends Mol Med. 2004 Sep; 10(9):417-20. PMID: 15350892.
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Bora NS, Sohn JH, Kang SG, Cruz JM, Nishihori H, Suk HJ, Wang Y, Kaplan HJ, Bora PS. Type I collagen is the autoantigen in experimental autoimmune anterior uveitis. J Immunol. 2004 Jun 01; 172(11):7086-94. PMID: 15153531.
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Bora PS, Guruge BL, Bora NS. Molecular characterization of human eye and heart fatty acid ethyl ester synthase/carboxylesterase by site-directed mutagenesis. Biochem Biophys Res Commun. 2003 Dec 26; 312(4):1094-8. PMID: 14651984.
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McLaughlin BJ, Fan W, Zheng JJ, Cai H, Del Priore LV, Bora NS, Kaplan HJ. Novel role for a complement regulatory protein (CD46) in retinal pigment epithelial adhesion. Invest Ophthalmol Vis Sci. 2003 Aug; 44(8):3669-74. PMID: 12882822.
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Bora PS, Hu Z, Tezel TH, Sohn JH, Kang SG, Cruz JM, Bora NS, Garen A, Kaplan HJ. Immunotherapy for choroidal neovascularization in a laser-induced mouse model simulating exudative (wet) macular degeneration. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2679-84. PMID: 12589025.
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Sohn JH, Bora PS, Suk HJ, Molina H, Kaplan HJ, Bora NS. Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Nat Med. 2003 Feb; 9(2):206-12. PMID: 12514742.
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Shao H, Sun D, Sun SL, Cruz JM, Bora N, Kaplan HJ. Expression of B7 molecules in the eye during the course of experimental autoimmune anterior uveitis (EAAU). Curr Eye Res. 2002; 25:271-277.
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Bora NS, Kabeer NH, Kim MC, Paryjas S, Atkinson JP, Kaplan HJ. Expression of the complement regulatory proteins in the normal and diseased (EAI) rat eye. Advances in Occular Immunology. 1994; 83-86.
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Bora NS, Bora PS, Kabeer NH, Gobelman CL, Fleischman JB, Kaplan HJ. Identification of a distinct 36kD circulating protein (P-36) in active pars planitis. Reg Immunol. 1994; 6:42-43.
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Bora NS, Chaplin D, Atkinson JP. Manual of Clinical Laboratory Immunology. Restriction fragment length polymorphism (RFLP) of complement proteins. 1992.
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Panchamoorthy G, Tiwari SC, Bora NS, Srivastava LM. Decreased expression of the C3b receptor (CR1) on the erythrocytes of patients with acute glomerulonephritis. Clin Chem Exzyme Comms. 1990; 2:167-176.
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Das N, Bora NS, Panchamoorthy G, Srivastava LM. Circulating immune complex in myocardial infarction. Indian J Med Res. 1987; 86:74 - 78.
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Bora NS, Srivastava LM. Status of complement system in Indian childhood cirrhosis (ICC). Current Sci. 1987; 56:344-345.
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Srivastava LM, Bora NS. Textbook of Biochemistry and Human Biology. Biochemistry of complement system. 1987.
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Bora PS, Bora NS, Srivastava LM. Lipoproteins and lipoprotein lipase in health and disease. J Indian Inst. 1986; 66:373-383.
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Sahai S, Srivastava N, Goel BK, Srivastava LM. Medical Genetics in India. Status of C3 component of complement and its genetic polymorphism in disease. 1985.
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Srivastava N, Gupta SP, Srivastava LM. Association between C3 complement types and bronchial asthma. Hum Hered. 1985; 35(4):263 - 264.
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Srivastava N, Srivastava LM. Association between C3 complement types and Indian childhood cirrhosis. Hum Hered. 1985; 35(4):268 - 270.
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Srivastava N, Gupta SP, Srivastava LM. Evaluation of complement (C3) inhibition in vitro by drugs used in the management of bronchial asthma. Asian Pac J Allergy Immunol. 1984; 2(2):237 - 240.
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Srivastava N, Gupta SP, Srivastava LM. Effect of house dust mite on serum complement activation and total haemolytic activity in vitro in normal subjects and in patients with bronchial asthma. Clin Allergy. 1983; 13(1):43 - 50.
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Srivastava LM, Srivastava N. Handbook of Practical Immunology. Complement System. 1982.
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Srivastava LM, Srivastava N. Genetic polymorphism of complement components: Functional differences and complement levels among the common C3 phenotypes. Recent Trends in Immunohaematology. 1982; 189-194.
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Srivastava N, Srivastava LM, Gupta SP. Studies on serum complement and IgE in bronchial asthma. Clinical Allergy. 1982; 12:569-576.
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Gupta SP, Srivastava LM, Srivastava N, Naidu YC. A study of bronchial asthma with particular reference to serum IgE and complement components. IRCS Med Sci. 1980; 8:132.
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Sahai S, Goel BK, Srivastava LM. Distribution of C3 phenotypes in North India: A pilot study. Hum Genet. 1978; 43:97-101.
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Gupta PD, Srivastava LM, Srivastava N. Immunocytochemical technique for localization of C3 component of complement. Curr Sci. 1978; 47:892.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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1990 | 1 | 1992 | 1 | 1994 | 2 | 2002 | 1 | 2003 | 4 | 2004 | 2 | 2005 | 2 | 2006 | 5 | 2007 | 9 | 2008 | 7 | 2009 | 12 | 2010 | 6 | 2011 | 7 | 2012 | 5 | 2014 | 3 | 2016 | 2 | 2019 | 1 | 2020 | 2 | 2022 | 1 | 2023 | 1 | 2024 | 1 |
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