Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages.

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Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages.

Conrad SJ, Raza T, Peterson EA, Liem J, Connor R, Nounamo B, Cannon M, Liu J. Myxoma virus lacking the host range determinant M062 stimulates cGAS-dependent type 1 interferon response and unique transcriptomic changes in human monocytes/macrophages. PLoS Pathog. 2022 09; 18(9):e1010316.

View in: PubMed

subject areas

Animals
Host Specificity
Humans
Interferon Type I
Intracellular Signaling Peptides and Proteins
Macrophages
Mammals
Monocytes
Myxoma virus
Nucleotidyltransferases
Poxviridae
Poxviridae Infections
Rabbits
Transcriptome
Vaccinia virus
Viral Proteins

authors with profiles

Martin Cannon