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Kenneth Knecht

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Cardiology
Address ACH Administration
1900 Maryland Street
Mail Slot # 512-3
Little Rock AR 72202
Phone501-364-1479
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    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Medical Director Ambulatory Care, Arkansas Children's Hospital

    Medical Director, Heart Transplant Program, Arkansas Children's Hospital


    Collapse Research 
    Collapse research activities and funding
    RPGACH     (BRENTS, LISA K)Jun 26, 2017 - Jul 31, 2019
    UAMS College of Medicine
    RSPGACH 17-DN-10
    Role: Principal Investigator
    ACRI #TBD     (MORAN, JEFFERY H)Jul 1, 2016 - Jun 30, 2019
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#TBD     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Deshpande SR, Zangwill SD, Richmond ME, Kindel SJ, Schroder JN, Gaglianello N, Bichell DP, Wigger MA, Knecht KR, Thrush PT, Mahle WT, North PE, Simpson PM, Zhang L, Dasgupta M, Tomita-Mitchell A, Mitchell ME. Evaluating threshold for donor fraction cell-free DNA using clinically available assay for rejection in pediatric and adult heart transplantation. Pediatr Transplant. 2024 May; 28(3):e14708. PMID: 38553812.
      View in: PubMed
    2. Theisen BW, Knecht KR, Daily JA. Mid-aortic syndrome diagnosed by transesophageal echocardiogram in a patient with dilated cardiomyopathy. Cardiol Young. 2023 May; 33(5):795-797. PMID: 37185169.
      View in: PubMed
    3. Godown J, Fountain D, Bansal N, Ameduri R, Anderson S, Beasley G, Burstein D, Knecht K, Molina K, Pye S, Richmond M, Spinner JA, Watanabe K, West S, Reinhardt Z, Scheel J, Urschel S, Villa C, Hollander SA. Heart Transplantation in Children With Down Syndrome. J Am Heart Assoc. 2022 05 17; 11(10):e024883. PMID: 35574952.
      View in: PubMed
    4. Richmond ME, Deshpande SR, Zangwill SD, Bichell DP, Kindel SJ, Mahle WT, Schroder JN, Wigger MA, Knecht KR, Pahl E, Gaglianello NA, Goetsch MA, Simpson P, Dasgupta M, Zhang L, North PE, Tomita-Mitchell A, Mitchell ME. Validation of donor fraction cell-free DNA with biopsy-proven cardiac allograft rejection in children and adults. J Thorac Cardiovasc Surg. 2023 02; 165(2):460-468.e2. PMID: 35643770.
      View in: PubMed
    5. Deshpande SR, Zangwill SD, Kindel SJ, Schroder JN, Bichell DP, Wigger MA, Richmond ME, Knecht KR, Pahl E, Gaglianello NA, Mahle WT, Stamm KD, Simpson PM, Dasgupta M, Zhang L, North PE, Tomita-Mitchell A, Mitchell ME. Relationship between donor fraction cell-free DNA and clinical rejection in heart transplantation. Pediatr Transplant. 2022 06; 26(4):e14264. PMID: 35258162.
      View in: PubMed
    6. Gambetta KE, McCulloch MA, Lal AK, Knecht K, Butts RJ, Villa CR, Johnson JN, Conway J, Bock MJ, Schumacher KR, Law SP, Friedland-Little JM, Deshpande SR, West SC, Lytrivi ID, Wittlieb-Weber CA. Diversity of Dystrophin Gene Mutations and Disease Progression in a Contemporary Cohort of Duchenne Muscular Dystrophy. Pediatr Cardiol. 2022 Apr; 43(4):855-867. PMID: 35064276.
      View in: PubMed
    7. Arthur L, Knecht K, Ferry J, Grigsby D, Spencer H, Zakaria D. Serial assessment of right ventricular function can detect acute cellular rejection in children with heart transplantation. Pediatr Transplant. 2022 06; 26(4):e14231. PMID: 35043516.
      View in: PubMed
    8. Kohli U, Desai L, Chowdhury D, Harahsheh AS, Yonts AB, Ansong A, Sabati A, Nguyen HH, Hussain T, Khan D, Parra DA, Su JA, Patel JK, Ronai C, Bohun M, Freij BJ, O'Connor MJ, Rosanno JW, Gupta A, Salavitabar A, Dorfman AL, Hansen J, Frosch O, Profita EL, Maskatia S, Thacker D, Shrivastava S, Harris TH, Feingold B, Berger S, Campbell M, Idriss SF, Das S, Renno MS, Knecht K, Asaki SY, Patel S, Ashwath R, Shih R, Phillips J, Das B, Ramachandran P, Sagiv E, Bhat AH, Johnson JN, Taggart NW, Imundo J, Nakra N, Behere S, Patel A, Aggarwal A, Aljemmali S, Lang S, Batlivala SP, Forsha DE, Conners GP, Shaw J, Smith FC, Pauliks L, Vettukattil J, Shaffer K, Cheang S, Voleti S, Shenoy R, Komarlu R, Ryan SJ, Snyder C, Bansal N, Sharma M, Robinson JA, Arnold SR, Salvatore CM, Kumar M, Fremed MA, Glickstein JS, Perrotta M, Orr W, Rozema T, Thirumoorthi M, Mullett CJ, Ang JY. mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis?in?Adolescents: A Survey Study. J Pediatr. 2022 04; 243:208-213.e3. PMID: 34952008.
      View in: PubMed
    9. Zangwill SD, Deshpande SR, Simpson PM, Liang HL, Zhang L, Dasgupta M, Richmond ME, Kindel SJ, Bichell DP, Mahle WT, Wigger MA, Schroder JN, Knecht KR, Pahl E, Gaglianello NA, North PE, Tomita-Mitchell A, Mitchell ME. Increase in nuclear cell-free DNA is associated with major adverse events in adult and pediatric heart transplant recipients. Clin Transplant. 2022 01; 36(1):e14509. PMID: 34649304.
      View in: PubMed
    10. Butto A, Mao CY, Wright L, Wetzel M, Kelleman MS, Carboni MP, Dipchand AI, Knecht KR, Reinhardt Z, Sparks JD, Villa C, Mahle WT. Relationship of ventricular assist device support duration with pediatric heart transplant outcomes. J Heart Lung Transplant. 2022 01; 41(1):61-69. PMID: 34688547.
      View in: PubMed
    11. Dykes JC, Rosenthal DN, Bernstein D, McElhinney DB, Chrisant MRK, Daly KP, Ameduri RK, Knecht K, Richmond ME, Lin KY, Urschel S, Simmonds J, Simpson KE, Albers EL, Khan A, Schumacher K, Almond CS, Chen S. Clinical and hemodynamic characteristics of the pediatric failing Fontan. J Heart Lung Transplant. 2021 12; 40(12):1529-1539. PMID: 34412962.
      View in: PubMed
    12. Amdani S, Simpson KE, Thrush P, Shih R, Simmonds J, Knecht K, Mogul DB, Hurley K, Koehl D, Cantor R, Naftel D, Kirklin JK, Daly KP. Hepatorenal dysfunction assessment with the Model for End-Stage Liver Disease Excluding INR score predicts worse survival after heart transplant in pediatric Fontan patients. J Thorac Cardiovasc Surg. 2022 04; 163(4):1462-1473.e12. PMID: 33745714.
      View in: PubMed
    13. Crawford RL, Bolin EH, Prodhan P, Renno MS, Knecht KR. Variable Presentation of COVID-19 in Pediatric Patients. Pediatr Infect Dis J. 2021 02 01; 40(2):e88-e90. PMID: 33433162.
      View in: PubMed
    14. McCulloch MA, Zuckerman WA, M?ller T, Knecht K, Lin KY, Beasley GS, Peng DM, Albert DC, Miera O, Dipchand AI, Kirk R, Davies RR. Effects of donor cause of death, ischemia time, inotrope exposure, troponin values, cardiopulmonary resuscitation, electrocardiographic and echocardiographic data on recipient outcomes: A review of the literature. Pediatr Transplant. 2020 05; 24(3):e13676. PMID: 32198808.
      View in: PubMed
    15. McCulloch MA, Lal AK, Knecht K, Butts RJ, Villa CR, Johnson JN, Conway J, Bock MJ, Schumacher KR, Law SP, Friedland-Little JM, Deshpande SR, West SC, Lytrivi ID, Gambetta KE, Wittlieb-Weber CA. Implantable Cardioverter Defibrillator Use in Males with Duchenne Muscular Dystrophy and Severe Left Ventricular Dysfunction. Pediatr Cardiol. 2020 Jun; 41(5):925-931. PMID: 32157397.
      View in: PubMed
    16. Wittlieb-Weber CA, Knecht KR, Villa CR, Cunningham C, Conway J, Bock MJ, Gambetta KE, Lal AK, Schumacher KR, Law SP, Deshpande SR, West SC, Friedland-Little JM, Lytrivi ID, McCulloch MA, Butts RJ, Weber DR, Johnson JN. Risk Factors for Cardiac and Non-cardiac Causes of Death in Males with Duchenne Muscular Dystrophy. Pediatr Cardiol. 2020 Apr; 41(4):764-771. PMID: 32016582.
      View in: PubMed
    17. Kirk R, Dipchand AI, Davies RR, Miera O, Chapman G, Conway J, Denfield S, Gossett JG, Johnson J, McCulloch M, Schweiger M, Zimpfer D, Ablonczy L, Adachi I, Albert D, Alexander P, Amdani S, Amodeo A, Azeka E, Ballweg J, Beasley G, B?hmer J, Butler A, Camino M, Castro J, Chen S, Chrisant M, Christen U, Danziger-Isakov L, Das B, Everitt M, Feingold B, Fenton M, Garcia-Guereta L, Godown J, Gupta D, Irving C, Joong A, Kemna M, Khulbey SK, Kindel S, Knecht K, Lal AK, Lin K, Lord K, M?ller T, Nandi D, Niesse O, Peng DM, P?rez-Blanco A, Punnoose A, Reinhardt Z, Rosenthal D, Scales A, Scheel J, Shih R, Smith J, Smits J, Thul J, Weintraub R, Zangwill S, Zuckerman WA. ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation. J Heart Lung Transplant. 2020 04; 39(4):331-341. PMID: 32088108.
      View in: PubMed
    18. Richmond ME, Zangwill SD, Kindel SJ, Deshpande SR, Schroder JN, Bichell DP, Knecht KR, Mahle WT, Wigger MA, Gaglianello NA, Pahl E, Simpson PM, Dasgupta M, North PE, Hidestrand M, Tomita-Mitchell A, Mitchell ME. Donor fraction cell-free DNA and rejection in adult and pediatric heart transplantation. J Heart Lung Transplant. 2020 05; 39(5):454-463. PMID: 31983667.
      View in: PubMed
    19. Barfuss SB, Butts R, Knecht KR, Prada-Ruiz A, Lal AK. Outcomes of Myocarditis in Patients with Normal Left Ventricular Systolic Function on Admission. Pediatr Cardiol. 2019 Aug; 40(6):1171-1174. PMID: 31177303.
      View in: PubMed
    20. Wittlieb-Weber CA, Villa CR, Conway J, Bock MJ, Gambetta KE, Johnson JN, Lal AK, Schumacher KR, Law SP, Deshpande SR, West SC, Friedland-Little JM, Lytrivi ID, McCulloch MA, Butts RJ, Weber DR, Knecht KR. Use of advanced heart failure therapies in Duchenne muscular dystrophy. Prog Pediatr Cardiol. 2019 Jun; 53:11-14. PMID: 31360053.
      View in: PubMed
    21. Butts RJ, Boyle GJ, Deshpande SR, Gambetta K, Knecht KR, Prada-Ruiz CA, Richmond ME, West SC, Lal AK. Characteristics of Clinically Diagnosed Pediatric Myocarditis in a Contemporary Multi-Center Cohort. Pediatr Cardiol. 2017 Aug; 38(6):1175-1182. PMID: 28536746.
      View in: PubMed
    22. Thomas TO, Knecht KR. Hypertrophic Cardiomyopathy in an Adolescent. J Ark Med Soc. 2016 Nov; 113(5):112-114. PMID: 30005461.
      View in: PubMed
    23. Zakaria D, Frazier E, Imamura M, Garcia X, Pye S, Knecht KR, Prodhan P, Gossett JR, Swearingen CJ, Morrow WR. Improved Survival While Waiting and Risk Factors for Death in Pediatric Patients Listed for Cardiac Transplantation. Pediatr Cardiol. 2017 Jan; 38(1):77-85. PMID: 27803956.
      View in: PubMed
    24. Greenway SC, Butts R, Naftel DC, Pruitt E, Kirklin JK, Larsen I, Urschel S, Knecht K, Law Y. Statin therapy is not associated with improved outcomes after heart transplantation in children and adolescents. J Heart Lung Transplant. 2016 Apr; 35(4):457-65. PMID: 26746989.
      View in: PubMed
    25. Knecht KR, Bryant J, Garcia X, Pye S, Prodhan P, Frazier EA. Heart Transplantation in the Short Term After Chemotherapy. J Pediatr Hematol Oncol. 2015 Jul; 37(5):409-10. PMID: 25493454.
      View in: PubMed
    26. Knecht KR, Glover A, Dossey AM, Rettiganti M, Gossett J, Frazier EA. Antibody-mediated rejection is associated with impaired graft function in pediatric heart transplant recipients. J Heart Lung Transplant. 2015 Aug; 34(8):1120-1. PMID: 25987310.
      View in: PubMed
    27. Auerbach SR, Kukreja M, Gilbert D, Bastardi H, Feingold B, Knecht K, Kaufman BD, Brown RN, Miyamoto SD. Maintenance steroid use at 30 days post-transplant and outcomes of pediatric heart transplantation: A propensity matched analysis of the Pediatric Heart Transplant Study database. J Heart Lung Transplant. 2015 Aug; 34(8):1066-72. PMID: 25980572.
      View in: PubMed
    28. Gupta P, Rettiganti M, Gossett JM, Gardner M, Bryant JC, Noel TR, Knecht KR. Longitudinal renal function in pediatric heart transplant recipients: 20-years experience. Pediatr Transplant. 2015 Mar; 19(2):182-7. PMID: 25484128.
      View in: PubMed
    29. Knecht KR. Cardiovascular safety of stimulant medications. J Child Adolesc Psychopharmacol. 2015 Mar; 25(2):181. PMID: 25386638.
      View in: PubMed
    30. Moore JP, Patel PA, Shannon KM, Albers EL, Salerno JC, Stein MA, Stephenson EA, Mohan S, Shah MJ, Asakai H, Pflaumer A, Czosek RJ, Everitt MD, Garnreiter JM, McCanta AC, Papez AL, Escudero C, Sanatani S, Cain NB, Kannankeril PJ, Bratincsak A, Mandapati R, Silva JN, Knecht KR, Balaji S. Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy. Heart Rhythm. 2014 Jul; 11(7):1163-9. PMID: 24751393.
      View in: PubMed
    31. Moore JP, Shannon KM, Albers EL, Et al, Knecht KR. Predictors of myocardial recovery in pediatric tachycardia-induced cardiomyopathy. Heart Rhythm. 2014.
    32. Pai V, Alexander A, Knecht K. The curious case of hypoxemia. Clin Pediatr (Phila). 2014 Mar; 53(3):300-2. PMID: 24336440.
      View in: PubMed
    33. Imamura M, Abraham B, Garcia X, Knecht KR, Frazier E, Shinkawa T. New transplant technique with hemiazygos continuation and interrupted inferior vena cava. Ann Thorac Surg. 2013 Nov; 96(5):1882-4. PMID: 24182488.
      View in: PubMed
    34. Knecht KR, MacLeod SL, Hobbs CA, Li M, Morrow WR. Gene expression profiling in pediatric heart transplant rejection. Int J Cardiol. 2013 Oct 12; 168(5):5052-3. PMID: 23972362.
      View in: PubMed
    35. O'Connor MJ, Harville TO, Rhodes-Clark B, Pye SE, Knecht KR, Imamura M, Frazier EA, Morrow WR. Quantification, identification, and relevance of anti-human leukocyte antigen antibodies formed in association with the berlin heart ventricular assist device in children. Transplantation. 2013 Jun 27; 95(12):1542-7. PMID: 23778570.
      View in: PubMed
    36. O'Connor MJ, Harville TO, Rhodes-Clark B, Pye SE, Knecht KR, Imamura M, Frazier EA, Morrow WR. Quantification, identification and relevance of anti-human leukocyte antibodies formed in association with the Berlin Heart ventricular assist device in Children. Transplantation. 2013; 95(12):1542-1547.
    37. Imamura M, Abraham B, Garcia X, Knecht KR, Frazier E, Shinkawa T. New transplant technique with hemiazygous continuation and interrupted inferior vena cava. Ann Thorac Surg. 2013; 96:1882-1884.
    38. Knecht KR, Morrow WR. Congenital Heart Disease. Transposition of the Great Arteries. 2013; 9.
    39. Wetzel GT, Knecht KR. Pediatric Right Bundle Branch Block. 2012.
    40. Knecht KR, Alexander ML, Swearingen CJ, Frazier EA. NTproBNP as a marker of rejection in pediatric heart transplant recipients. Pediatr Transplant. 2012 Jun; 16(4):335-9. PMID: 22429516.
      View in: PubMed
    41. Morrow WR, Frazier EA, Mahle WT, Harville TO, Pye SE, Knecht KR, Howard EL, Smith RN, Saylors RL, Garcia X, Jaquiss RD, Woodle ES. Rapid reduction in donor-specific anti-human leukocyte antigen antibodies and reversal of antibody-mediated rejection with bortezomib in pediatric heart transplant patients. Transplantation. 2012 Feb 15; 93(3):319-24. PMID: 22179403.
      View in: PubMed
    42. Knecht KR, Imamura M. Atrial septal dissection late after congenital heart surgery. Ann Thorac Surg. 2011 Oct; 92(4):1522-4. PMID: 21958812.
      View in: PubMed
    43. Knecht KR, Imamura M. Atrial septal dissection late following congenital heart surgery. Ann of Thor Surg. 2011; 92:1522-1524.
    44. Knecht KR, Morrow WR. The Handbook of Growth and Growth Monitoring in Health and Disease. Growth following pediatric heart transplantation. 2011; 111.
    45. Knecht KR, Frazier EA, Garcia X, Morrow WR. Danon Disease in Pediatric Heart Transplantation. 31st Annual Meeting and Scientific Sessions. 2011.
    46. Knecht KR, Leffler CW. Distinct effects of intravascular and extravascular angiotensin II on cerebrovascular circulation of newborn pigs. Exp Biol Med (Maywood). 2010 Dec; 235(12):1479-88. PMID: 21127344.
      View in: PubMed
    47. Knecht KR, Milam S, Wilkinson DA, Fedinec AL, Leffler CW. Time-dependent action of carbon monoxide on the newborn cerebrovascular circulation. Am J Physiol Heart Circ Physiol. 2010 Jul; 299(1):H70-5. PMID: 20435844.
      View in: PubMed
    48. Knecht KR, Seller JD, Alpert BS. Korotkoff sounds in neonates, infants, and toddlers. Am J Cardiol. 2009 Apr 15; 103(8):1165-7. PMID: 19361608.
      View in: PubMed
    49. Knecht KR, Leffler CW. Actions of angiotensin II in neonatal cerebrovascular circulation. 2009; 3(5).
    50. Knecht K. Effects of Angiotensin II in neonatal Cerebrovascular circulation. 2008.
    51. Ralston ME, Euwema MS, Knecht KR, Et al. comparison of levalbuterol and racemic albuterol with ipratropium bromid in acute pediatric asthma: a randomized controlled trial. Journal of Emergency Medicine. 2005; 29(1):29-35.
    52. Ralston ME, Euwema MS, Knecht KR, Ziolkowski TJ, Coakley TA, Cline SM. Comparison of levalbuterol and racemic albuterol combined with ipratropium bromide in acute pediatric asthma: a randomized controlled trial. J Emerg Med. 2005 Jul; 29(1):29-35. PMID: 15961004.
      View in: PubMed
    53. Rhodes LV, Huang C, Sanchez AJ, Nichol ST, Zaki SR, Ksiazek TG, Humphreys JG, Freeman JJ, Knecht KR. Hantavirus pulmonary syndrome associated with monogahela virus, Pennsylvania. Emerging Infectious Diseases. 2000; 6(6):616-621.
    54. Mishriki Y, Knecht K. Felinization of the esophagus. Postgraduate Medicine. 1999; 106(6).
    55. Knecht K, Mishriki T. Oral ulcer due to Wegener's Granulomatosis. Postgraduate Medicine. 1999; 105(5).
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