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Connection

Piotr Zimniak to Isoenzymes

This is a "connection" page, showing publications Piotr Zimniak has written about Isoenzymes.

 
Connection Strength
  
 
 
1.344
  
  1. Singh SP, Zimniak L, Zimniak P. The human hGSTA5 gene encodes an enzymatically active protein. Biochim Biophys Acta. 2010 Jan; 1800(1):16-22.
    View in: PubMed
    Score: 0.326
  2. Ji X, Blaszczyk J, Xiao B, O'Donnell R, Hu X, Herzog C, Singh SV, Zimniak P. Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1. Biochemistry. 1999 Aug 10; 38(32):10231-8.
    View in: PubMed
    Score: 0.163
  3. Ayyadevara S, Engle MR, Singh SP, Dandapat A, Lichti CF, Benes H, Shmookler Reis RJ, Liebau E, Zimniak P. Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. Aging Cell. 2005 Oct; 4(5):257-71.
    View in: PubMed
    Score: 0.062
  4. Singh SV, Varma V, Zimniak P, Srivastava SK, Marynowski SW, Desai D, Amin S, Ji X. Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide. Biochemistry. 2004 Aug 03; 43(30):9708-15.
    View in: PubMed
    Score: 0.058
  5. Sharma R, Brown D, Awasthi S, Yang Y, Sharma A, Patrick B, Saini MK, Singh SP, Zimniak P, Singh SV, Awasthi YC. Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells. Eur J Biochem. 2004 May; 271(9):1690-701.
    View in: PubMed
    Score: 0.057
  6. Bose C, Guo J, Zimniak L, Srivastava SK, Singh SP, Zimniak P, Singh SV. Critical role of allyl groups and disulfide chain in induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally occurring chemopreventive agent in garlic. Carcinogenesis. 2002 Oct; 23(10):1661-5.
    View in: PubMed
    Score: 0.051
  7. Yang Y, Sharma R, Zimniak P, Awasthi YC. Role of alpha class glutathione S-transferases as antioxidant enzymes in rodent tissues. Toxicol Appl Pharmacol. 2002 Jul 15; 182(2):105-15.
    View in: PubMed
    Score: 0.050
  8. Pal A, Gu Y, Herzog C, Srivastava SK, Zimniak P, Ji X, Singh SV. Role of arginine 216 in catalytic activity of murine Alpha class glutathione transferases mGSTAl-1 and mGSTA2-2 toward carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. Carcinogenesis. 2001 Aug; 22(8):1301-5.
    View in: PubMed
    Score: 0.047
  9. Pal A, Desai DH, Amin S, Srivastava SK, Hu X, Herzog C, Zimniak P, Singh SV. Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers. FEBS Lett. 2000 Dec 08; 486(2):163-6.
    View in: PubMed
    Score: 0.045
  10. Pal A, Hu X, Zimniak P, Singh SV. Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of alpha, beta-unsaturated aldehydes. Cancer Lett. 2000 Jun 01; 154(1):39-43.
    View in: PubMed
    Score: 0.043
  11. Srivastava SK, Singhal SS, Hu X, Awasthi YC, Zimniak P, Singh SV. Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa. Arch Biochem Biophys. 1999 Jun 01; 366(1):89-94.
    View in: PubMed
    Score: 0.040
  12. Hu X, Herzog C, Zimniak P, Singh SV. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. Cancer Res. 1999 May 15; 59(10):2358-62.
    View in: PubMed
    Score: 0.040
  13. Hu X, Xia H, Srivastava SK, Pal A, Awasthi YC, Zimniak P, Singh SV. Catalytic efficiencies of allelic variants of human glutathione S-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene. Cancer Res. 1998 Dec 01; 58(23):5340-3.
    View in: PubMed
    Score: 0.039
  14. Hu X, Pal A, Krzeminski J, Amin S, Awasthi YC, Zimniak P, Singh SV. Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes. Carcinogenesis. 1998 Sep; 19(9):1685-9.
    View in: PubMed
    Score: 0.038
  15. Hu X, O'Donnell R, Srivastava SK, Xia H, Zimniak P, Nanduri B, Bleicher RJ, Awasthi S, Awasthi YC, Ji X, Singh SV. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene. Biochem Biophys Res Commun. 1997 Jun 18; 235(2):424-8.
    View in: PubMed
    Score: 0.035
  16. Awasthi S, Singhal SS, Srivastava SK, Chaubey M, Piper JT, Zimniak P, Yallampalli C, Rajaraman S, Awasthi YC. Rat GST 8-8 is expressed predominantly in myeloid origin cells infiltrating the gravid uterus. Int J Biochem Cell Biol. 1997 May; 29(5):807-13.
    View in: PubMed
    Score: 0.035
  17. He NG, Singhal SS, Chaubey M, Awasthi S, Zimniak P, Partridge CA, Awasthi YC. Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells. Biochim Biophys Acta. 1996 Dec 06; 1291(3):182-8.
    View in: PubMed
    Score: 0.034
  18. He NG, Singhal SS, Srivastava SK, Zimniak P, Awasthi YC, Awasthi S. Transfection of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme, mouse GSTA4-4, confers doxorubicin resistance to Chinese hamster ovary cells. Arch Biochem Biophys. 1996 Sep 01; 333(1):214-20.
    View in: PubMed
    Score: 0.033
  19. Singhal SS, Awasthi S, Srivastava SK, Zimniak P, Ansari NH, Awasthi YC. Novel human ocular glutathione S-transferases with high activity toward 4-hydroxynonenal. Invest Ophthalmol Vis Sci. 1995 Jan; 36(1):142-50.
    View in: PubMed
    Score: 0.030
  20. Singhal SS, Zimniak P, Awasthi S, Piper JT, He NG, Teng JI, Petersen DR, Awasthi YC. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch Biochem Biophys. 1994 Jun; 311(2):242-50.
    View in: PubMed
    Score: 0.028
  21. Singhal SS, Zimniak P, Sharma R, Srivastava SK, Awasthi S, Awasthi YC. A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues. Biochim Biophys Acta. 1994 Feb 16; 1204(2):279-86.
    View in: PubMed
    Score: 0.028
  22. Gong H, Singh SV, Singh SP, Mu Y, Lee JH, Saini SP, Toma D, Ren S, Kagan VE, Day BW, Zimniak P, Xie W. Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells. Mol Endocrinol. 2006 Feb; 20(2):279-90.
    View in: PubMed
    Score: 0.016
  23. Wu Z, Minhas GS, Wen D, Jiang H, Chen K, Zimniak P, Zheng J. Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors. J Med Chem. 2004 Jun 03; 47(12):3282-94.
    View in: PubMed
    Score: 0.014
  24. Cheng JZ, Singhal SS, Sharma A, Saini M, Yang Y, Awasthi S, Zimniak P, Awasthi YC. Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling. Arch Biochem Biophys. 2001 Aug 15; 392(2):197-207.
    View in: PubMed
    Score: 0.012
  25. Cheng JZ, Yang Y, Singh SP, Singhal SS, Awasthi S, Pan SS, Singh SV, Zimniak P, Awasthi YC. Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues. Biochem Biophys Res Commun. 2001 Apr 20; 282(5):1268-74.
    View in: PubMed
    Score: 0.011
  26. York JL, Maddox LC, Zimniak P, McHugh TE, Grant DF. Reduction of MTT by glutathione S-transferase. Biotechniques. 1998 Oct; 25(4):622-4, 626-8.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.