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Connection

Piotr Zimniak to Humans

This is a "connection" page, showing publications Piotr Zimniak has written about Humans.

 
Connection Strength
  
 
 
0.226
  
  1. Anisimov VN, Bartke A, Barzilai N, Batin MA, Blagosklonny MV, Brown-Borg H, Budovskaya Y, Campisi J, Friguet B, Fraifeld V, Franceschi C, Gems D, Gladyshev V, Gorbunova V, Gudkov AV, Kennedy B, Konovalenko M, Kraemer B, Moskalev A, Petropoulos I, Pasyukova E, Rattan S, Rogina B, Seluanov A, Shaposhnikov M, Shmookler Reis R, Tavernarakis N, Vijg J, Yashin A, Zimniak P. The second international conference "genetics of aging and longevity". Aging (Albany NY). 2012 May; 4(5):305-17.
    View in: PubMed
    Score: 0.017
  2. Zimniak P. Relationship of electrophilic stress to aging. Free Radic Biol Med. 2011 Sep 15; 51(6):1087-105.
    View in: PubMed
    Score: 0.016
  3. Singh SP, Zimniak L, Zimniak P. The human hGSTA5 gene encodes an enzymatically active protein. Biochim Biophys Acta. 2010 Jan; 1800(1):16-22.
    View in: PubMed
    Score: 0.014
  4. Zimniak P. Detoxification reactions: relevance to aging. Ageing Res Rev. 2008 Dec; 7(4):281-300.
    View in: PubMed
    Score: 0.013
  5. Raufman JP, Cheng K, Zimniak P. Activation of muscarinic receptor signaling by bile acids: physiological and medical implications. Dig Dis Sci. 2003 Aug; 48(8):1431-44.
    View in: PubMed
    Score: 0.009
  6. Ji X, Blaszczyk J, Xiao B, O'Donnell R, Hu X, Herzog C, Singh SV, Zimniak P. Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1. Biochemistry. 1999 Aug 10; 38(32):10231-8.
    View in: PubMed
    Score: 0.007
  7. Zimniak P, Pikula S, Bandorowicz-Pikula J, Awasthi YC. Mechanisms for xenobiotic transport in biological membranes. Toxicol Lett. 1999 Jun 01; 106(2-3):107-18.
    View in: PubMed
    Score: 0.007
  8. Ji X, Tordova M, O'Donnell R, Parsons JF, Hayden JB, Gilliland GL, Zimniak P. Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase. Biochemistry. 1997 Aug 12; 36(32):9690-702.
    View in: PubMed
    Score: 0.006
  9. Zimniak L, Awasthi S, Srivastava SK, Zimniak P. Increased resistance to oxidative stress in transfected cultured cells overexpressing glutathione S-transferase mGSTA4-4. Toxicol Appl Pharmacol. 1997 Mar; 143(1):221-9.
    View in: PubMed
    Score: 0.006
  10. Zimniak P, Nanduri B, Pikula S, Bandorowicz-Pikula J, Singhal SS, Srivastava SK, Awasthi S, Awasthi YC. Naturally occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties. Eur J Biochem. 1994 Sep 15; 224(3):893-9.
    View in: PubMed
    Score: 0.005
  11. Lester R, Zimniak P. True transport: one or more sodium-dependent bile acid transporters? Hepatology. 1993 Nov; 18(5):1279-82.
    View in: PubMed
    Score: 0.005
  12. Zimniak P. Dubin-Johnson and Rotor syndromes: molecular basis and pathogenesis. Semin Liver Dis. 1993 Aug; 13(3):248-60.
    View in: PubMed
    Score: 0.005
  13. Zimniak P, Awasthi S, Awasthi YC. Phase III detoxification system. Trends Biochem Sci. 1993 May; 18(5):164-6.
    View in: PubMed
    Score: 0.005
  14. Zimniak P, Awasthi YC. ATP-dependent transport systems for organic anions. Hepatology. 1993 Feb; 17(2):330-9.
    View in: PubMed
    Score: 0.004
  15. Apidianakis Y, Que YA, Xu W, Tegos GP, Zimniak P, Hamblin MR, Tompkins RG, Xiao W, Rahme LG. Down-regulation of glutatione S-transferase a 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB J. 2012 Feb; 26(2):730-7.
    View in: PubMed
    Score: 0.004
  16. Zimniak P, Radominska A, Lester R. The pathogenesis of cholestasis. Hosp Pract (Off Ed). 1990 Aug 15; 25(8):107-11, 114-8, 123-5.
    View in: PubMed
    Score: 0.004
  17. Ahmed BA, Bukhari IA, Jeffus BC, Harney JT, Thyparambil S, Ziu E, Fraer M, Rusch NJ, Zimniak P, Lupashin V, Tang D, Kilic F. The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network. PLoS One. 2009; 4(3):e4730.
    View in: PubMed
    Score: 0.003
  18. Sharma A, Sharma R, Chaudhary P, Vatsyayan R, Pearce V, Jeyabal PV, Zimniak P, Awasthi S, Awasthi YC. 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells. Arch Biochem Biophys. 2008 Dec 15; 480(2):85-94.
    View in: PubMed
    Score: 0.003
  19. Sharma R, Sharma A, Dwivedi S, Zimniak P, Awasthi S, Awasthi YC. 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. Biochemistry. 2008 Jan 08; 47(1):143-56.
    View in: PubMed
    Score: 0.003
  20. Li J, Sharma R, Patrick B, Sharma A, Jeyabal PV, Reddy PM, Saini MK, Dwivedi S, Dhanani S, Ansari NH, Zimniak P, Awasthi S, Awasthi YC. Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal. Biochemistry. 2006 Oct 10; 45(40):12253-64.
    View in: PubMed
    Score: 0.003
  21. Gong H, Singh SV, Singh SP, Mu Y, Lee JH, Saini SP, Toma D, Ren S, Kagan VE, Day BW, Zimniak P, Xie W. Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells. Mol Endocrinol. 2006 Feb; 20(2):279-90.
    View in: PubMed
    Score: 0.003
  22. McEwen JE, Zimniak P, Mehta JL, Shmookler Reis RJ. Molecular pathology of aging and its implications for senescent coronary atherosclerosis. Curr Opin Cardiol. 2005 Sep; 20(5):399-406.
    View in: PubMed
    Score: 0.003
  23. Patrick B, Li J, Jeyabal PV, Reddy PM, Yang Y, Sharma R, Sinha M, Luxon B, Zimniak P, Awasthi S, Awasthi YC. Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression. Biochem Biophys Res Commun. 2005 Aug 26; 334(2):425-32.
    View in: PubMed
    Score: 0.003
  24. Gu Y, Guo J, Pal A, Pan SS, Zimniak P, Singh SV, Ji X. Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity. Biochemistry. 2004 Dec 21; 43(50):15673-9.
    View in: PubMed
    Score: 0.003
  25. Singh SV, Varma V, Zimniak P, Srivastava SK, Marynowski SW, Desai D, Amin S, Ji X. Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide. Biochemistry. 2004 Aug 03; 43(30):9708-15.
    View in: PubMed
    Score: 0.002
  26. Wu Z, Minhas GS, Wen D, Jiang H, Chen K, Zimniak P, Zheng J. Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors. J Med Chem. 2004 Jun 03; 47(12):3282-94.
    View in: PubMed
    Score: 0.002
  27. Sharma R, Brown D, Awasthi S, Yang Y, Sharma A, Patrick B, Saini MK, Singh SP, Zimniak P, Singh SV, Awasthi YC. Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells. Eur J Biochem. 2004 May; 271(9):1690-701.
    View in: PubMed
    Score: 0.002
  28. Yang Y, Yang Y, Trent MB, He N, Lick SD, Zimniak P, Awasthi YC, Boor PJ. Glutathione-S-transferase A4-4 modulates oxidative stress in endothelium: possible role in human atherosclerosis. Atherosclerosis. 2004 Apr; 173(2):211-21.
    View in: PubMed
    Score: 0.002
  29. Cheng K, Zimniak P, Raufman JP. Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells. Cancer Res. 2003 Oct 15; 63(20):6744-50.
    View in: PubMed
    Score: 0.002
  30. Awasthi S, Singhal SS, Sharma R, Zimniak P, Awasthi YC. Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistance. Int J Cancer. 2003 Sep 20; 106(5):635-46.
    View in: PubMed
    Score: 0.002
  31. Yang Y, Sharma A, Sharma R, Patrick B, Singhal SS, Zimniak P, Awasthi S, Awasthi YC. Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis. J Biol Chem. 2003 Oct 17; 278(42):41380-8.
    View in: PubMed
    Score: 0.002
  32. Awasthi S, Singhal SS, Singhal J, Cheng J, Zimniak P, Awasthi YC. Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76. Int J Oncol. 2003 Apr; 22(4):713-20.
    View in: PubMed
    Score: 0.002
  33. Singhal SS, Singhal J, Sharma R, Singh SV, Zimniak P, Awasthi YC, Awasthi S. Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells. Int J Oncol. 2003 Feb; 22(2):365-75.
    View in: PubMed
    Score: 0.002
  34. Raufman JP, Chen Y, Zimniak P, Cheng K. Deoxycholic acid conjugates are muscarinic cholinergic receptor antagonists. Pharmacology. 2002 Aug; 65(4):215-21.
    View in: PubMed
    Score: 0.002
  35. Awasthi S, Sharma R, Yang Y, Singhal SS, Pikula S, Bandorowicz-Pikula J, Singh SV, Zimniak P, Awasthi YC. Transport functions and physiological significance of 76 kDa Ral-binding GTPase activating protein (RLIP76). Acta Biochim Pol. 2002; 49(4):855-67.
    View in: PubMed
    Score: 0.002
  36. Sharma R, Singhal SS, Cheng J, Yang Y, Sharma A, Zimniak P, Awasthi S, Awasthi YC. RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes. Arch Biochem Biophys. 2001 Jul 15; 391(2):171-9.
    View in: PubMed
    Score: 0.002
  37. Cheng JZ, Yang Y, Singh SP, Singhal SS, Awasthi S, Pan SS, Singh SV, Zimniak P, Awasthi YC. Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues. Biochem Biophys Res Commun. 2001 Apr 20; 282(5):1268-74.
    View in: PubMed
    Score: 0.002
  38. Awasthi S, Cheng JZ, Singhal SS, Pandya U, Sharma R, Singh SV, Zimniak P, Awasthi YC. Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences. Biochemistry. 2001 Apr 03; 40(13):4159-68.
    View in: PubMed
    Score: 0.002
  39. Singhal SS, Singhal J, Cheng J, Pikula S, Sharma R, Zimniak P, Awasthi YC, Awasthi S. Purification and functional reconstitution of intact ral-binding Gtpase activating protein, RLIP76, in artificial liposomes. Acta Biochim Pol. 2001; 48(2):551-62.
    View in: PubMed
    Score: 0.002
  40. Pal A, Desai DH, Amin S, Srivastava SK, Hu X, Herzog C, Zimniak P, Singh SV. Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers. FEBS Lett. 2000 Dec 08; 486(2):163-6.
    View in: PubMed
    Score: 0.002
  41. Pandya U, Srivastava SK, Singhal SS, Pal A, Awasthi S, Zimniak P, Awasthi YC, Singh SV. Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil. Biochem Biophys Res Commun. 2000 Nov 11; 278(1):258-62.
    View in: PubMed
    Score: 0.002
  42. Awasthi S, Cheng J, Singhal SS, Saini MK, Pandya U, Pikula S, Bandorowicz-Pikula J, Singh SV, Zimniak P, Awasthi YC. Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin. Biochemistry. 2000 Aug 08; 39(31):9327-34.
    View in: PubMed
    Score: 0.002
  43. Pal A, Hu X, Zimniak P, Singh SV. Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of alpha, beta-unsaturated aldehydes. Cancer Lett. 2000 Jun 01; 154(1):39-43.
    View in: PubMed
    Score: 0.002
  44. Sharma R, Awasthi S, Zimniak P, Awasthi YC. Transport of glutathione-conjugates in human erythrocytes. Acta Biochim Pol. 2000; 47(3):751-62.
    View in: PubMed
    Score: 0.002
  45. Cheng JZ, Singhal SS, Saini M, Singhal J, Piper JT, Van Kuijk FJ, Zimniak P, Awasthi YC, Awasthi S. Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells. Arch Biochem Biophys. 1999 Dec 01; 372(1):29-36.
    View in: PubMed
    Score: 0.002
  46. Srivastava SK, Singhal SS, Hu X, Awasthi YC, Zimniak P, Singh SV. Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa. Arch Biochem Biophys. 1999 Jun 01; 366(1):89-94.
    View in: PubMed
    Score: 0.002
  47. Hu X, Herzog C, Zimniak P, Singh SV. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. Cancer Res. 1999 May 15; 59(10):2358-62.
    View in: PubMed
    Score: 0.002
  48. Awasthi S, Singhal SS, Pandya U, Gopal S, Zimniak P, Singh SV, Awasthi YC. ATP-Dependent colchicine transport by human erythrocyte glutathione conjugate transporter. Toxicol Appl Pharmacol. 1999 Mar 15; 155(3):215-26.
    View in: PubMed
    Score: 0.002
  49. Hu X, Xia H, Srivastava SK, Pal A, Awasthi YC, Zimniak P, Singh SV. Catalytic efficiencies of allelic variants of human glutathione S-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene. Cancer Res. 1998 Dec 01; 58(23):5340-3.
    View in: PubMed
    Score: 0.002
  50. Hu X, Pal A, Krzeminski J, Amin S, Awasthi YC, Zimniak P, Singh SV. Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes. Carcinogenesis. 1998 Sep; 19(9):1685-9.
    View in: PubMed
    Score: 0.002
  51. Awasthi S, Singhal SS, Srivastava SK, Torman RT, Zimniak P, Bandorowicz-Pikula J, Singh SV, Piper JT, Awasthi YC, Pikula S. ATP-Dependent human erythrocyte glutathione-conjugate transporter. I. Purification, photoaffinity labeling, and kinetic characteristics of ATPase activity. Biochemistry. 1998 Apr 14; 37(15):5231-8.
    View in: PubMed
    Score: 0.002
  52. Awasthi S, Singhal SS, Pikula S, Piper JT, Srivastava SK, Torman RT, Bandorowicz-Pikula J, Lin JT, Singh SV, Zimniak P, Awasthi YC. ATP-Dependent human erythrocyte glutathione-conjugate transporter. II. Functional reconstitution of transport activity. Biochemistry. 1998 Apr 14; 37(15):5239-48.
    View in: PubMed
    Score: 0.002
  53. Janecki AJ, Montrose MH, Zimniak P, Zweibaum A, Tse CM, Khurana S, Donowitz M. Subcellular redistribution is involved in acute regulation of the brush border Na+/H+ exchanger isoform 3 in human colon adenocarcinoma cell line Caco-2. Protein kinase C-mediated inhibition of the exchanger. J Biol Chem. 1998 Apr 10; 273(15):8790-8.
    View in: PubMed
    Score: 0.002
  54. Hu X, Xia H, Srivastava SK, Herzog C, Awasthi YC, Ji X, Zimniak P, Singh SV. Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons. Biochem Biophys Res Commun. 1997 Sep 18; 238(2):397-402.
    View in: PubMed
    Score: 0.002
  55. Hu X, Ji X, Srivastava SK, Xia H, Awasthi S, Nanduri B, Awasthi YC, Zimniak P, Singh SV. Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene. Arch Biochem Biophys. 1997 Sep 01; 345(1):32-8.
    View in: PubMed
    Score: 0.002
  56. Hu X, O'Donnell R, Srivastava SK, Xia H, Zimniak P, Nanduri B, Bleicher RJ, Awasthi S, Awasthi YC, Ji X, Singh SV. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene. Biochem Biophys Res Commun. 1997 Jun 18; 235(2):424-8.
    View in: PubMed
    Score: 0.002
  57. Awasthi S, Singhal SS, He N, Chaubey M, Zimniak P, Srivastava SK, Singh SV, Awasthi YC. Modulation of doxorubicin cytotoxicity by ethacrynic acid. Int J Cancer. 1996 Nov 04; 68(3):333-9.
    View in: PubMed
    Score: 0.001
  58. Singhal SS, Awasthi S, Srivastava SK, Zimniak P, Ansari NH, Awasthi YC. Novel human ocular glutathione S-transferases with high activity toward 4-hydroxynonenal. Invest Ophthalmol Vis Sci. 1995 Jan; 36(1):142-50.
    View in: PubMed
    Score: 0.001
  59. Singhal SS, Zimniak P, Awasthi S, Piper JT, He NG, Teng JI, Petersen DR, Awasthi YC. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch Biochem Biophys. 1994 Jun; 311(2):242-50.
    View in: PubMed
    Score: 0.001
  60. Awasthi S, Singhal SS, Srivastava SK, Zimniak P, Bajpai KK, Saxena M, Sharma R, Ziller SA, Frenkel EP, Singh SV, et al. Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoprotein. J Clin Invest. 1994 Mar; 93(3):958-65.
    View in: PubMed
    Score: 0.001
  61. Singhal SS, Zimniak P, Sharma R, Srivastava SK, Awasthi S, Awasthi YC. A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues. Biochim Biophys Acta. 1994 Feb 16; 1204(2):279-86.
    View in: PubMed
    Score: 0.001
  62. Saxena M, Singhal SS, Awasthi S, Singh SV, Labelle EF, Zimniak P, Awasthi YC. Dinitrophenyl S-glutathione ATPase purified from human muscle catalyzes ATP hydrolysis in the presence of leukotrienes. Arch Biochem Biophys. 1992 Oct; 298(1):231-7.
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    Score: 0.001
  63. Drake RR, Zimniak P, Haley BE, Lester R, Elbein AD, Radominska A. Synthesis and characterization of 5-azido-UDP-glucuronic acid. A new photoaffinity probe for UDP-glucuronic acid-utilizing proteins. J Biol Chem. 1991 Dec 05; 266(34):23257-60.
    View in: PubMed
    Score: 0.001
  64. Singhal SS, Sharma R, Gupta S, Ahmad H, Zimniak P, Radominska A, Lester R, Awasthi YC. The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl)glutathione ATPase of human erythrocyte. FEBS Lett. 1991 Apr 09; 281(1-2):255-7.
    View in: PubMed
    Score: 0.001
  65. Awasthi YC, Singhal SS, Gupta S, Ahmad H, Zimniak P, Radominska A, Lester R, Sharma R. Purification and characterization of an ATPase from human liver which catalyzes ATP hydrolysis in the presence of the conjugates of bilirubin bile acids and glutathione. Biochem Biophys Res Commun. 1991 Mar 29; 175(3):1090-6.
    View in: PubMed
    Score: 0.001
  66. Irshaid YM, Radominska A, Zimniak P, Zimniak A, Lester R, Tephly TR. Glucuronidation of monohydroxylated short chain bile acids by human liver microsomes and purified human liver UDP-glucuronosyltransferases. Drug Metab Dispos. 1991 Jan-Feb; 19(1):173-7.
    View in: PubMed
    Score: 0.001
  67. Radominska A, Comer KA, Zimniak P, Falany J, Iscan M, Falany CN. Human liver steroid sulphotransferase sulphates bile acids. Biochem J. 1990 Dec 15; 272(3):597-604.
    View in: PubMed
    Score: 0.001
  68. Radominska-Pyrek A, Zimniak P, Irshaid YM, Lester R, Tephly TR, St Pyrek J. Glucuronidation of 6 alpha-hydroxy bile acids by human liver microsomes. J Clin Invest. 1987 Jul; 80(1):234-41.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.