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Connection

Piotr Zimniak to Aldehydes

This is a "connection" page, showing publications Piotr Zimniak has written about Aldehydes.

 
Connection Strength
  
 
 
3.997
  
  1. Zimniak P. 4-Hydroxynonenal and fat storage: A paradoxical pro-obesity mechanism? Cell Cycle. 2010 Sep 01; 9(17):3393-4.
    View in: PubMed
    Score: 0.356
  2. Singh SP, Niemczyk M, Saini D, Sadovov V, Zimniak L, Zimniak P. Disruption of the mGsta4 gene increases life span of C57BL mice. J Gerontol A Biol Sci Med Sci. 2010 Jan; 65(1):14-23.
    View in: PubMed
    Score: 0.335
  3. Singh SP, Niemczyk M, Zimniak L, Zimniak P. Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE). Aging (Albany NY). 2008 Dec 18; 1(1):68-80.
    View in: PubMed
    Score: 0.316
  4. Singh SP, Niemczyk M, Saini D, Awasthi YC, Zimniak L, Zimniak P. Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice. Biochemistry. 2008 Mar 25; 47(12):3900-11.
    View in: PubMed
    Score: 0.299
  5. Ayyadevara S, Dandapat A, Singh SP, Siegel ER, Shmookler Reis RJ, Zimniak L, Zimniak P. Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. Mech Ageing Dev. 2007 Feb; 128(2):196-205.
    View in: PubMed
    Score: 0.274
  6. Ayyadevara S, Engle MR, Singh SP, Dandapat A, Lichti CF, Benes H, Shmookler Reis RJ, Liebau E, Zimniak P. Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. Aging Cell. 2005 Oct; 4(5):257-71.
    View in: PubMed
    Score: 0.253
  7. Singh SP, Chen T, Chen L, Mei N, McLain E, Samokyszyn V, Thaden JJ, Moore MM, Zimniak P. Mutagenic effects of 4-hydroxynonenal triacetate, a chemically protected form of the lipid peroxidation product 4-hydroxynonenal, as assayed in L5178Y/Tk+/- mouse lymphoma cells. J Pharmacol Exp Ther. 2005 May; 313(2):855-61.
    View in: PubMed
    Score: 0.242
  8. Engle MR, Singh SP, Czernik PJ, Gaddy D, Montague DC, Ceci JD, Yang Y, Awasthi S, Awasthi YC, Zimniak P. Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse. Toxicol Appl Pharmacol. 2004 Feb 01; 194(3):296-308.
    View in: PubMed
    Score: 0.225
  9. Nanduri B, Zimniak P. Role of active-site residues 107 and 108 of glutathione S-transferase mGSTA4-4 in determining the catalytic properties of the enzyme for 4-hydroxynonenal. Arch Biochem Biophys. 1999 Feb 01; 362(1):167-74.
    View in: PubMed
    Score: 0.159
  10. Nanduri B, Hayden JB, Awasthi YC, Zimniak P. Amino acid residue 104 in an alpha-class glutathione S-transferase is essential for the high selectivity and specificity of the enzyme for 4-hydroxynonenal. Arch Biochem Biophys. 1996 Nov 15; 335(2):305-10.
    View in: PubMed
    Score: 0.137
  11. Shearn CT, Fritz KS, Shearn AH, Saba LM, Mercer KE, Engi B, Galligan JJ, Zimniak P, Orlicky DJ, Ronis MJ, Petersen DR. Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice. Redox Biol. 2016 Apr; 7:68-77.
    View in: PubMed
    Score: 0.128
  12. Ronis MJ, Mercer KE, Gannon B, Engi B, Zimniak P, Shearn CT, Orlicky DJ, Albano E, Badger TM, Petersen DR. Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-a double knockout mice enhance injury during early stages of alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 01; 308(5):G403-15.
    View in: PubMed
    Score: 0.120
  13. Zimniak P. Relationship of electrophilic stress to aging. Free Radic Biol Med. 2011 Sep 15; 51(6):1087-105.
    View in: PubMed
    Score: 0.094
  14. Singh SP, Zimniak L, Zimniak P. The human hGSTA5 gene encodes an enzymatically active protein. Biochim Biophys Acta. 2010 Jan; 1800(1):16-22.
    View in: PubMed
    Score: 0.082
  15. Sharma A, Sharma R, Chaudhary P, Vatsyayan R, Pearce V, Jeyabal PV, Zimniak P, Awasthi S, Awasthi YC. 4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells. Arch Biochem Biophys. 2008 Dec 15; 480(2):85-94.
    View in: PubMed
    Score: 0.078
  16. Sharma R, Sharma A, Dwivedi S, Zimniak P, Awasthi S, Awasthi YC. 4-Hydroxynonenal self-limits fas-mediated DISC-independent apoptosis by promoting export of Daxx from the nucleus to the cytosol and its binding to Fas. Biochemistry. 2008 Jan 08; 47(1):143-56.
    View in: PubMed
    Score: 0.074
  17. Li J, Sharma R, Patrick B, Sharma A, Jeyabal PV, Reddy PM, Saini MK, Dwivedi S, Dhanani S, Ansari NH, Zimniak P, Awasthi S, Awasthi YC. Regulation of CD95 (Fas) expression and Fas-mediated apoptotic signaling in HLE B-3 cells by 4-hydroxynonenal. Biochemistry. 2006 Oct 10; 45(40):12253-64.
    View in: PubMed
    Score: 0.068
  18. Patrick B, Li J, Jeyabal PV, Reddy PM, Yang Y, Sharma R, Sinha M, Luxon B, Zimniak P, Awasthi S, Awasthi YC. Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression. Biochem Biophys Res Commun. 2005 Aug 26; 334(2):425-32.
    View in: PubMed
    Score: 0.063
  19. Sharma R, Brown D, Awasthi S, Yang Y, Sharma A, Patrick B, Saini MK, Singh SP, Zimniak P, Singh SV, Awasthi YC. Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells. Eur J Biochem. 2004 May; 271(9):1690-701.
    View in: PubMed
    Score: 0.057
  20. Yang Y, Sharma A, Sharma R, Patrick B, Singhal SS, Zimniak P, Awasthi S, Awasthi YC. Cells preconditioned with mild, transient UVA irradiation acquire resistance to oxidative stress and UVA-induced apoptosis: role of 4-hydroxynonenal in UVA-mediated signaling for apoptosis. J Biol Chem. 2003 Oct 17; 278(42):41380-8.
    View in: PubMed
    Score: 0.054
  21. Singhal SS, Singhal J, Sharma R, Singh SV, Zimniak P, Awasthi YC, Awasthi S. Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells. Int J Oncol. 2003 Feb; 22(2):365-75.
    View in: PubMed
    Score: 0.053
  22. Sharma R, Sharma A, Yang Y, Awasthi S, Singhal SS, Zimniak P, Awasthi YC. Functional reconstitution of Ral-binding GTPase activating protein, RLIP76, in proteoliposomes catalyzing ATP-dependent transport of glutathione conjugate of 4-hydroxynonenal. Acta Biochim Pol. 2002; 49(3):693-701.
    View in: PubMed
    Score: 0.049
  23. Cheng JZ, Sharma R, Yang Y, Singhal SS, Sharma A, Saini MK, Singh SV, Zimniak P, Awasthi S, Awasthi YC. Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress. J Biol Chem. 2001 Nov 02; 276(44):41213-23.
    View in: PubMed
    Score: 0.048
  24. Cheng JZ, Singhal SS, Sharma A, Saini M, Yang Y, Awasthi S, Zimniak P, Awasthi YC. Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling. Arch Biochem Biophys. 2001 Aug 15; 392(2):197-207.
    View in: PubMed
    Score: 0.047
  25. Singh SP, Coronella JA, Benes H, Cochrane BJ, Zimniak P. Catalytic function of Drosophila melanogaster glutathione S-transferase DmGSTS1-1 (GST-2) in conjugation of lipid peroxidation end products. Eur J Biochem. 2001 May; 268(10):2912-23.
    View in: PubMed
    Score: 0.047
  26. Cheng JZ, Yang Y, Singh SP, Singhal SS, Awasthi S, Pan SS, Singh SV, Zimniak P, Awasthi YC. Two distinct 4-hydroxynonenal metabolizing glutathione S-transferase isozymes are differentially expressed in human tissues. Biochem Biophys Res Commun. 2001 Apr 20; 282(5):1268-74.
    View in: PubMed
    Score: 0.046
  27. Pal A, Hu X, Zimniak P, Singh SV. Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of alpha, beta-unsaturated aldehydes. Cancer Lett. 2000 Jun 01; 154(1):39-43.
    View in: PubMed
    Score: 0.044
  28. Cheng JZ, Singhal SS, Saini M, Singhal J, Piper JT, Van Kuijk FJ, Zimniak P, Awasthi YC, Awasthi S. Effects of mGST A4 transfection on 4-hydroxynonenal-mediated apoptosis and differentiation of K562 human erythroleukemia cells. Arch Biochem Biophys. 1999 Dec 01; 372(1):29-36.
    View in: PubMed
    Score: 0.042
  29. Xiao B, Singh SP, Nanduri B, Awasthi YC, Zimniak P, Ji X. Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface. Biochemistry. 1999 Sep 14; 38(37):11887-94.
    View in: PubMed
    Score: 0.042
  30. He NG, Singhal SS, Chaubey M, Awasthi S, Zimniak P, Partridge CA, Awasthi YC. Purification and characterization of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme from bovine pulmonary microvessel endothelial cells. Biochim Biophys Acta. 1996 Dec 06; 1291(3):182-8.
    View in: PubMed
    Score: 0.034
  31. He NG, Singhal SS, Srivastava SK, Zimniak P, Awasthi YC, Awasthi S. Transfection of a 4-hydroxynonenal metabolizing glutathione S-transferase isozyme, mouse GSTA4-4, confers doxorubicin resistance to Chinese hamster ovary cells. Arch Biochem Biophys. 1996 Sep 01; 333(1):214-20.
    View in: PubMed
    Score: 0.034
  32. Singhal SS, Awasthi S, Srivastava SK, Zimniak P, Ansari NH, Awasthi YC. Novel human ocular glutathione S-transferases with high activity toward 4-hydroxynonenal. Invest Ophthalmol Vis Sci. 1995 Jan; 36(1):142-50.
    View in: PubMed
    Score: 0.030
  33. Singhal SS, Zimniak P, Awasthi S, Piper JT, He NG, Teng JI, Petersen DR, Awasthi YC. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch Biochem Biophys. 1994 Jun; 311(2):242-50.
    View in: PubMed
    Score: 0.029
  34. Apidianakis Y, Que YA, Xu W, Tegos GP, Zimniak P, Hamblin MR, Tompkins RG, Xiao W, Rahme LG. Down-regulation of glutatione S-transferase a 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB J. 2012 Feb; 26(2):730-7.
    View in: PubMed
    Score: 0.024
  35. Dwivedi S, Sharma R, Sharma A, Zimniak P, Ceci JD, Awasthi YC, Boor PJ. The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (-/-) mice. Toxicology. 2006 Jan 20; 218(1):58-66.
    View in: PubMed
    Score: 0.016
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.