Surrogate markers, emboldened and boxed warnings, and an expanding culture of misinformation: evidence-based clinical science should guide FDA decision making about product labeling.
Shulman LP, Bateman LH, Creinin MD, Cullins VE, Doyle LL, Godfrey E, Murphy P, Rodriguez P, Spear SJ, Stewart FH, Thomas MA, Westhoff CL, Worthington S. Surrogate markers, emboldened and boxed warnings, and an expanding culture of misinformation: evidence-based clinical science should guide FDA decision making about product labeling. Contraception. 2006 May; 73(5):440-2.