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Connection

John Imig to Hypertension

This is a "connection" page, showing publications John Imig has written about Hypertension.

 
Connection Strength
  
 
 
8.826
  
  1. Goorani S, Zangene S, Imig JD. Hypertension: A Continuing Public Healthcare Issue. Int J Mol Sci. 2024 Dec 26; 26(1).
    View in: PubMed
    Score: 0.722
  2. Imig JD. Bioactive lipids in hypertension. Adv Pharmacol. 2023; 97:1-35.
    View in: PubMed
    Score: 0.645
  3. Imig JD, Khan MAH, Stavniichuk A, Jankiewicz WK, Goorani S, Yeboah MM, El-Meanawy A. Salt-sensitive hypertension after reversal of unilateral ureteral obstruction. Biochem Pharmacol. 2023 04; 210:115438.
    View in: PubMed
    Score: 0.632
  4. Imig JD. Orally active epoxyeicosatrienoic acid analogs in hypertension and renal injury. Adv Pharmacol. 2022; 94:27-55.
    View in: PubMed
    Score: 0.597
  5. Yeboah MM, Hye Khan MA, Chesnik MA, Sharma A, Paudyal MP, Falck JR, Imig JD. The epoxyeicosatrienoic acid analog PVPA ameliorates cyclosporine-induced hypertension and renal injury in rats. Am J Physiol Renal Physiol. 2016 09 01; 311(3):F576-85.
    View in: PubMed
    Score: 0.401
  6. Hye Khan MA, Sharma A, Rarick KR, Roman RJ, Harder DR, Imig JD. Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats. PLoS One. 2015; 10(12):e0145335.
    View in: PubMed
    Score: 0.386
  7. Imig JD. Epoxyeicosatrienoic acids, hypertension, and kidney injury. Hypertension. 2015 Mar; 65(3):476-82.
    View in: PubMed
    Score: 0.362
  8. Hye Khan MA, Neck?r J, Cummens B, Wahl GM, Imig JD. Azilsartan decreases renal and cardiovascular injury in the spontaneously hypertensive obese rat. Cardiovasc Drugs Ther. 2014 Aug; 28(4):313-22.
    View in: PubMed
    Score: 0.351
  9. Imig JD, Walsh KA, Hye Khan MA, Nagasawa T, Cherian-Shaw M, Shaw SM, Hammock BD. Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor ? agonist improve vascular function and decrease renal injury in hypertensive obese rats. Exp Biol Med (Maywood). 2012 Dec; 237(12):1402-12.
    View in: PubMed
    Score: 0.313
  10. Khan AH, Imig JD. Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome. Am J Hypertens. 2011 Jul; 24(7):816-21.
    View in: PubMed
    Score: 0.278
  11. Imig JD. Targeting epoxides for organ damage in hypertension. J Cardiovasc Pharmacol. 2010 Oct; 56(4):329-35.
    View in: PubMed
    Score: 0.269
  12. Imig JD. 20-hydroxyeicosatetraenoic acid and angiotensin: a positive feedback system to cause hypertension. Hypertension. 2010 Nov; 56(5):822-3.
    View in: PubMed
    Score: 0.268
  13. Elmarakby AA, Imig JD. Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats. Clin Sci (Lond). 2010 Feb; 118(4):291-301.
    View in: PubMed
    Score: 0.257
  14. Imig JD. Adenosine2A receptors and epoxyeicosatrienoic acids: a recipe for salt and blood pressure regulation. Hypertension. 2009 Dec; 54(6):1223-5.
    View in: PubMed
    Score: 0.252
  15. Manhiani M, Quigley JE, Knight SF, Tasoobshirazi S, Moore T, Brands MW, Hammock BD, Imig JD. Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension. Am J Physiol Renal Physiol. 2009 Sep; 297(3):F740-8.
    View in: PubMed
    Score: 0.246
  16. Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD. Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clin Sci (Lond). 2009 Jan; 116(1):61-70.
    View in: PubMed
    Score: 0.238
  17. Elmarakby AA, Quigley JE, Olearczyk JJ, Sridhar A, Cook AK, Inscho EW, Pollock DM, Imig JD. Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension. 2007 Dec; 50(6):1069-76.
    View in: PubMed
    Score: 0.219
  18. Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD. An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol. 2005 Dec; 46(6):842-8.
    View in: PubMed
    Score: 0.193
  19. Imig JD, Zhao X, Zaharis CZ, Olearczyk JJ, Pollock DM, Newman JW, Kim IH, Watanabe T, Hammock BD. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension. 2005 Oct; 46(4):975-81.
    View in: PubMed
    Score: 0.190
  20. Inscho EW, Cook AK, Murzynowski JB, Imig JD. Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation. J Hypertens. 2004 Apr; 22(4):811-8.
    View in: PubMed
    Score: 0.172
  21. Imig JD, Zhao X, Capdevila JH, Morisseau C, Hammock BD. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension. 2002 Feb; 39(2 Pt 2):690-4.
    View in: PubMed
    Score: 0.148
  22. Imig JD, Inscho EW. Adaptations of the renal microcirculation to hypertension. Microcirculation. 2002; 9(4):315-28.
    View in: PubMed
    Score: 0.147
  23. Imig JD, Jankiewicz WK, Khan AH. Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture. Hypertension. 2020 07; 76(1):3-15.
    View in: PubMed
    Score: 0.132
  24. Vackov? ?, Kikerlov? S, Melenovsky V, Kol?r F, Imig JD, Kompanowska-Jezierska E, Sadowski J, Cervenka L. Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure. Kidney Blood Press Res. 2019; 44(4):792-809.
    View in: PubMed
    Score: 0.125
  25. Cervenka L, Huskov? Z, Kopkan L, Kikerlov? S, Sedl?kov? L, Vanourkov? Z, Al?nov? P, Kol?r F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neck?r J. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. J Hypertens. 2018 06; 36(6):1326-1341.
    View in: PubMed
    Score: 0.114
  26. Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy. J Am Soc Nephrol. 2015 Mar; 26(3):597-610.
    View in: PubMed
    Score: 0.088
  27. Kujal P, Cert?kov? Ch?bov? V, ?karoupkov? P, Huskov? Z, Vernerov? Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Cervenka L. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clin Exp Pharmacol Physiol. 2014 Mar; 41(3):227-37.
    View in: PubMed
    Score: 0.085
  28. Cabral PD, Hong NJ, Hye Khan MA, Ortiz PA, Beierwaltes WH, Imig JD, Garvin JL. Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II. Hypertension. 2014 Mar; 63(3):e68-73.
    View in: PubMed
    Score: 0.084
  29. Honetschl?gerov? Z, Kitada K, Huskov? Z, Sporkov? A, Kopkan L, B?rgelov? M, Varcabov? ?, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerov? Z, Cervenka L. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. J Hypertens. 2013 Feb; 31(2):321-32.
    View in: PubMed
    Score: 0.079
  30. Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. FASEB J. 2010 Oct; 24(10):3770-81.
    View in: PubMed
    Score: 0.066
  31. Cert?kov? Ch?bov? V, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kujal P, Vernerov? Z, Vanourkov? Z, Kopkan L, Kramer HJ, Falck JR, Imig JD, Hammock BD, Vaneckov? I, Cervenka L. Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. Clin Sci (Lond). 2010 Feb 23; 118(10):617-32.
    View in: PubMed
    Score: 0.065
  32. Quigley R, Chakravarty S, Zhao X, Imig JD, Capdevila JH. Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice. Nephron Physiol. 2009; 113(4):p23-8.
    View in: PubMed
    Score: 0.062
  33. Elmarakby AA, Quigley JE, Imig JD, Pollock JS, Pollock DM. TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2008 Jan; 294(1):R76-83.
    View in: PubMed
    Score: 0.055
  34. Cert?kov? Ch?bov? V, Kramer HJ, Vaneckov? I, Thumov? M, Skaroupkov? P, Tesar V, Falck JR, Imig JD, Cervenka L. The roles of intrarenal 20-hydroxyeicosatetraenoic and epoxyeicosatrienoic acids in the regulation of renal function in hypertensive Ren-2 transgenic rats. Kidney Blood Press Res. 2007; 30(5):335-46.
    View in: PubMed
    Score: 0.054
  35. Kang KT, Sullivan JC, Sasser JM, Imig JD, Pollock JS. Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats. Hypertension. 2007 Apr; 49(4):893-901.
    View in: PubMed
    Score: 0.052
  36. Elmarakby AA, Williams JM, Imig JD, Pollock JS, Pollock DM. Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension. Vascul Pharmacol. 2007 Feb; 46(2):144-51.
    View in: PubMed
    Score: 0.051
  37. Jin L, Ying Z, Hilgers RH, Yin J, Zhao X, Imig JD, Webb RC. Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats. J Pharmacol Exp Ther. 2006 Jul; 318(1):288-95.
    View in: PubMed
    Score: 0.049
  38. Lee DL, Sturgis LC, Labazi H, Osborne JB, Fleming C, Pollock JS, Manhiani M, Imig JD, Brands MW. Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. Am J Physiol Heart Circ Physiol. 2006 Mar; 290(3):H935-40.
    View in: PubMed
    Score: 0.048
  39. Zhao X, Cook AK, Field M, Edwards B, Zhang S, Zhang Z, Pollock JS, Imig JD, Inscho EW. Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension. Hypertension. 2005 Sep; 46(3):562-8.
    View in: PubMed
    Score: 0.047
  40. Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obes Res. 2004 Aug; 12(8):1278-89.
    View in: PubMed
    Score: 0.044
  41. Wang MH, Smith A, Zhou Y, Chang HH, Lin S, Zhao X, Imig JD, Dorrance AM. Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension. Hypertension. 2003 Oct; 42(4):594-9.
    View in: PubMed
    Score: 0.041
  42. Zhuo JL, Imig JD, Hammond TG, Orengo S, Benes E, Navar LG. Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor. Hypertension. 2002 Jan; 39(1):116-21.
    View in: PubMed
    Score: 0.037
  43. Cert?kov? Ch?bov? V, Kujal P, Vanourkov? Z, ?karoupkov? P, Sadowski J, Kompanowska-Jezierska E, Tesar V, Hammock B, Imig J, Maxov? H, Cervenka L, Vaneckov? I. Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats. Kidney Blood Press Res. 2019; 44(6):1493-1505.
    View in: PubMed
    Score: 0.032
  44. Widiapradja A, Manteufel EJ, Dehlin HM, Pena J, Goldspink PH, Sharma A, Kolb LL, Imig JD, Janicki JS, Lu B, Levick SP. Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart. Sci Rep. 2019 07 29; 9(1):11004.
    View in: PubMed
    Score: 0.031
  45. Cert?kov? Ch?bov? V, Kujal P, ?karoupkov? P, Varnourkov? Z, Vackov? ?, Huskov? Z, Kikerlov? S, Sadowski J, Kompanowska-Jezierska E, Baranowska I, Hwang SH, Hammock BD, Imig JD, Tesar V, Cervenka L. Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. Kidney Blood Press Res. 2018; 43(2):329-349.
    View in: PubMed
    Score: 0.028
  46. Campbell WB, Imig JD, Schmitz JM, Falck JR. Orally Active Epoxyeicosatrienoic Acid Analogs. J Cardiovasc Pharmacol. 2017 Oct; 70(4):211-224.
    View in: PubMed
    Score: 0.027
  47. Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW, Geurts AM, Staruschenko A, Imig JD, Sorokin A. p66Shc regulates renal vascular tone in hypertension-induced nephropathy. J Clin Invest. 2016 07 01; 126(7):2533-46.
    View in: PubMed
    Score: 0.025
  48. Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Clin Exp Pharmacol Physiol. 2013 Apr; 40(4):273-81.
    View in: PubMed
    Score: 0.020
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.