Antithrombins
"Antithrombins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
Descriptor ID |
D000991
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MeSH Number(s) |
D27.505.519.389.745.800.449 D27.505.954.502.119.500
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Concept/Terms |
Antithrombins- Antithrombins
- Direct Thrombin Inhibitors
- Thrombin Inhibitors, Direct
- Direct Antithrombins
- Antithrombins, Direct
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Below are MeSH descriptors whose meaning is more general than "Antithrombins".
Below are MeSH descriptors whose meaning is more specific than "Antithrombins".
This graph shows the total number of publications written about "Antithrombins" by people in UAMS Profiles by year, and whether "Antithrombins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2020 | 1 | 0 | 1 | 2019 | 1 | 1 | 2 | 2018 | 0 | 1 | 1 | 2017 | 1 | 1 | 2 | 2016 | 0 | 1 | 1 | 2015 | 1 | 1 | 2 | 2014 | 2 | 2 | 4 | 2013 | 1 | 1 | 2 | 1988 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antithrombins" by people in Profiles over the past ten years.
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Bhogal S, Mukherjee D, Bagai J, Truong HT, Panchal HB, Murtaza G, Zaman M, Sachdeva R, Paul TK. Bivalirudin Versus Heparin During Intervention in Acute Coronary Syndrome: A Systematic Review of Randomized Trials. Cardiovasc Hematol Disord Drug Targets. 2020; 20(1):3-15.
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Mallidi J, Ulahannan J, Chaubey VK, Atreya AR, Shakoor MT, Fisher D, Garb J, Lotfi A. Comparison of Clinical Outcomes: Bivalirudin With Transfemoral Access Versus Heparin With Transradial Access in Patients With ST segment Elevation Myocardial Infarction. Crit Pathw Cardiol. 2019 09; 18(3):130-134.
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Kattoor AJ, Pothineni NV, Goel A, Syed M, Syed S, Paydak H, Mehta JL. Prescription Patterns and Outcomes of Patients With Atrial Fibrillation Treated With Direct Oral Anticoagulants and Warfarin: A Real-World Analysis. J Cardiovasc Pharmacol Ther. 2019 09; 24(5):428-434.
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Jain N, Reilly RF. Clinical Pharmacology of Oral Anticoagulants in Patients with Kidney Disease. Clin J Am Soc Nephrol. 2019 02 07; 14(2):278-287.
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Kaatz S, Mahan CE, Nakhle A, Gunasekaran K, Ali M, Lavender R, Paje DG. Management of Elective Surgery and Emergent Bleeding with Direct Oral Anticoagulants. Curr Cardiol Rep. 2017 10 24; 19(12):124.
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Saad M, Nairooz R, Rashed A, Abdelaziz HK, Mentias A, Abbott JD. Bivalirudin versus heparin in women undergoing percutaneous coronary intervention: A systematic review and meta-analysis of randomized clinical trials. Cardiovasc Revasc Med. 2017 Sep; 18(6):418-424.
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Omran J, Abdullah O, Abu-Fadel M, Gray WA, Firwana B, Drachman DE, Mahmud E, Aronow HD, White CJ, Al-Dadah AS. Hemorrhagic and ischemic outcomes of Heparin vs. Bivalirudin in carotid artery stenting: A meta-analysis of studies. Catheter Cardiovasc Interv. 2017 Mar 01; 89(4):746-753.
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Nairooz R, Sardar P, Amin H, Chatterjee S, Helmy T, Naidu SS. Short- and long-term outcomes in diabetes patients undergoing percutaneous coronary intervention with bivalirudin compared with heparin and glycoprotein IIb/IIIA inhibitors: A meta-analysis of randomized trials. Catheter Cardiovasc Interv. 2015 Sep; 86(3):364-75.
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Kupchak BR, McKenzie AL, Luk HY, Saenz C, Kunces LJ, Ellis LA, Vingren JL, Lee EC, Ballard KD, Johnson EC, Kavouras SA, Ganio MS, Wingo JE, Williamson KH, Armstrong LE. Effect of cycling in the heat for 164 km on procoagulant and fibrinolytic parameters. Eur J Appl Physiol. 2015 Jun; 115(6):1295-303.
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Federman M, Dragomer D, Grant S, Reemtsen B, Biniwale R. Use of bivalirudin for anticoagulation during implantation of total artificial heart. J Extra Corpor Technol. 2014 Jun; 46(2):170-2.
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Nairooz R, Sardar P, Amin H, Swaminathan RV, Kim LK, Chatterjee S, Feldman DN. Meta-analysis of randomized clinical trials comparing bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in patients undergoing percutaneous coronary intervention and in patients with ST-segment elevation myocardial infarction. Am J Cardiol. 2014 Jul 15; 114(2):250-9.
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Bain J, Oyler DR, Smyth SS, Macaulay TE. Pathophysiology and pharmacologic treatment of venous thromboembolism. Curr Drug Targets. 2014 Feb; 15(2):199-209.
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Byrnes JW, Swearingen CJ, Prodhan P, Fiser R, Dyamenahalli U. Antithrombin III supplementation on extracorporeal membrane oxygenation: impact on heparin dose and circuit life. ASAIO J. 2014 Jan-Feb; 60(1):57-62.
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Turagam MK, Addepally NS, Velagapudi P. Novel anticoagulants for stroke prevention in atrial fibrillation and chronic kidney disease. Expert Rev Cardiovasc Ther. 2013 Oct; 11(10):1297-9.
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