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Usama Hussein

TitlePost Doctoral Fellow
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Hematology
Address800 Marshall Street
Mail Slot # 512-10
Little Rock AR 72202
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    Dr. Usama Hussein is a post doctoral fellow of cancer biology at the peds pediatric hematology/oncology for Research at Arkansas Children Hospital Research Institute and joined the department in 2022. He completed his fellowship of Oncology at Jeonbuk National University Medical School and Jeonbuk National University Hospital in Republic of South Korea in 2021. He performed his residence for research fellowship in molecular and pharmaceutical science at Saarland University, Germany in 2015. He trained and earned his PhD degree at Beni-Suef University in a collaboration with Mitchel Cancer Institute, University of South Alabama in the oncologic science in 2013-2015. Dr. Hussein has several publications and scientific poster presentations/abstracts and is a reviewer in several peer reviewed journals. His research interests are osteosarcoma and gynecologic cancers including breast cancer, high grade serous ovarian carcinoma. Moreover, he has interests in genomic instability, DNA damage and repair mechanisms as well. His recent research is study gene regulations based on Next Generation Sequencing platforms like RNA-seq, ChIP-seq, DNA-seq, and analysis of big data using Python, R particularly biocManager libraries and machine learning.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Ahn SW, Lee CM, Kang MA, Hussein UK, Park HS, Ahn AR, Yu HC, Yang JD, Yang YH, Park K, Lee J, Jang KY, Park SH. IL4Ra and IL13Ra1 Are Involved in the Development of Human Gallbladder Cancer. J Pers Med. 2022 Feb 09; 12(2). PMID: 35207737.
      View in: PubMed
    2. Ahn AR, Noh SJ, Hussein UK, Park HS, Chung MJ, Lee H, Moon WS, Kang MJ, Kim HJ, Lee NR, Jang KY, Kim KM. FAM83H and Nectin1 expression are related with survival and relapse of bladder urothelial carcinoma patients. BMC Urol. 2021 Oct 08; 21(1):143. PMID: 34625065.
      View in: PubMed
    3. Hussein UK, Ahmed AG, Song Y, Kim KM, Moon YJ, Ahn AR, Park HS, Ahn SJ, Park SH, Kim JR, Jang KY. CK2a/CSNK2A1 Induces Resistance to Doxorubicin through SIRT6-Mediated Activation of the DNA Damage Repair Pathway. Cells. 2021 07 13; 10(7). PMID: 34359939.
      View in: PubMed
    4. Amin SN, Khashaba AS, Latif NSA, El Gazzar WB, Hussein UK. Citicoline improved cardiovascular function in animal model of dysautonomia. J Physiol Pharmacol. 2021 Feb; 72(1). PMID: 34099586.
      View in: PubMed
    5. Hussein UK, Ahmed AG, Choi WK, Kim KM, Park SH, Park HS, Noh SJ, Lee H, Chung MJ, Moon WS, Kang MJ, Cho DH, Jang KY. SCRIB Is Involved in the Progression of Ovarian Carcinomas in Association with the Factors Linked to Epithelial-to-Mesenchymal Transition and Predicts Shorter Survival of Diagnosed Patients. Biomolecules. 2021 03 09; 11(3). PMID: 33803371.
      View in: PubMed
    6. Kim KM, Hussein UK, Park SH, Moon YJ, Zhang Z, Ahmed AG, Ahn AR, Park HS, Kim JR, Jang KY. Expression of IL4Ra and IL13Ra1 are associated with poor prognosis of soft-tissue sarcoma of the extremities, superficial trunk, and retroperitoneum. Diagn Pathol. 2021 Jan 09; 16(1):2. PMID: 33419470.
      View in: PubMed
    7. Zhang Z, Ha SH, Moon YJ, Hussein UK, Song Y, Kim KM, Park SH, Park HS, Park BH, Ahn AR, Lee SA, Ahn SJ, Kim JR, Jang KY. Inhibition of SIRT6 potentiates the anti-tumor effect of doxorubicin through suppression of the DNA damage repair pathway in osteosarcoma. J Exp Clin Cancer Res. 2020 Nov 17; 39(1):247. PMID: 33198792.
      View in: PubMed
    8. Munakarmi S, Chand L, Shin HB, Hussein UK, Yun BS, Park HR, Jeong YJ. Anticancer effects of Poncirus fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion. Oncol Rep. 2020 12; 44(6):2537-2546. PMID: 33125135.
      View in: PubMed
    9. Hussein UK, Ha SH, Ahmed AG, Kim KM, Park SH, Kim CY, Kwon KS, Zhang Z, Lee SA, Park HS, Park BH, Lee H, Chung MJ, Moon WS, Kang MJ, Jang KY. FAM83H and SCRIB stabilize ß-catenin and stimulate progression of gastric carcinoma. Aging (Albany NY). 2020 06 20; 12(12):11812-11834. PMID: 32564009.
      View in: PubMed
    10. Ahn SW, Ahn AR, Ha SH, Hussein UK, Do Yang J, Kim KM, Park HS, Park SH, Yu HC, Jang KY. Expression of FAM83H and ZNF16 are associated with shorter survival of patients with gallbladder carcinoma. Diagn Pathol. 2020 May 27; 15(1):63. PMID: 32460791.
      View in: PubMed
    11. Ahmed AG, Hussein UK, Ahmed AE, Kim KM, Mahmoud HM, Hammouda O, Jang KY, Bishayee A. Mustard Seed (Brassica nigra) Extract Exhibits Antiproliferative Effect against Human Lung Cancer Cells through Differential Regulation of Apoptosis, Cell Cycle, Migration, and Invasion. Molecules. 2020 Apr 29; 25(9). PMID: 32365503.
      View in: PubMed
    12. Kim KM, Hussein UK, Park SH, Kang MA, Moon YJ, Zhang Z, Song Y, Park HS, Bae JS, Park BH, Ha SH, Moon WS, Kim JR, Jang KY. FAM83H is involved in stabilization of ß-catenin and progression of osteosarcomas. J Exp Clin Cancer Res. 2019 Jun 18; 38(1):267. PMID: 31215499.
      View in: PubMed
    13. Kim KM, Hussein UK, Bae JS, Park SH, Kwon KS, Ha SH, Park HS, Lee H, Chung MJ, Moon WS, Kang MJ, Jang KY. The Expression Patterns of FAM83H and PANX2 Are Associated With Shorter Survival of Clear Cell Renal Cell Carcinoma Patients. Front Oncol. 2019; 9:14. PMID: 30723706.
      View in: PubMed
    14. Kessler SM, Hosseini K, Hussein UK, Kim KM, List M, Schultheiß CS, Schulz MH, Laggai S, Jang KY, Kiemer AK. Hepatocellular Carcinoma and Nuclear Paraspeckles: Induction in Chemoresistance and Prediction for Poor Survival. Cell Physiol Biochem. 2019; 52(4):787-801. PMID: 30946555.
      View in: PubMed
    15. Bae JS, Noh SJ, Kim KM, Park SH, Hussein UK, Park HS, Park BH, Ha SH, Lee H, Chung MJ, Moon WS, Cho DH, Jang KY. SIRT6 Is Involved in the Progression of Ovarian Carcinomas via ß-Catenin-Mediated Epithelial to Mesenchymal Transition. Front Oncol. 2018; 8:538. PMID: 30524965.
      View in: PubMed
    16. Hussein UK, Park HS, Bae JS, Kim KM, Chong YJ, Kim CY, Kwon KS, Chung MJ, Lee H, Kang MJ, Moon WS, Jang KY. Expression of oxidized protein tyrosine phosphatase and ?H2AX predicts poor survival of gastric carcinoma patients. BMC Cancer. 2018 Aug 20; 18(1):836. PMID: 30126387.
      View in: PubMed
    17. Park HJ, Bae JS, Kim KM, Moon YJ, Park SH, Ha SH, Hussein UK, Zhang Z, Park HS, Park BH, Moon WS, Kim JR, Jang KY. The PARP inhibitor olaparib potentiates the effect of the DNA damaging agent doxorubicin in osteosarcoma. J Exp Clin Cancer Res. 2018 May 21; 37(1):107. PMID: 29784019.
      View in: PubMed
    18. Amin SN, Hussein UK, Yassa HD, Hassan SS, Rashed LA. Synergistic actions of vitamin D and metformin on skeletal muscles and insulin resistance of type 2 diabetic rats. J Cell Physiol. 2018 08; 233(8):5768-5779. PMID: 29205344.
      View in: PubMed
    19. Hussein UK, Hassan NEY, Elhalwagy MEA, Zaki AR, Abubakr HO, Nagulapalli Venkata KC, Jang KY, Bishayee A. Ginger and Propolis Exert Neuroprotective Effects against Monosodium Glutamate-Induced Neurotoxicity in Rats. Molecules. 2017 Nov 08; 22(11). PMID: 29117134.
      View in: PubMed
    20. Schultheiss CS, Laggai S, Czepukojc B, Hussein UK, List M, Barghash A, Tierling S, Hosseini K, Golob-Schwarzl N, Pokorny J, Hachenthal N, Schulz M, Helms V, Walter J, Zimmer V, Lammert F, Bohle RM, Dandolo L, Haybaeck J, Kiemer AK, Kessler SM. The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma. Cell Stress. 2017 Aug 25; 1(1):37-54. PMID: 31225433.
      View in: PubMed
    21. Hussein UK, Mahmoud HM, Farrag AG, Bishayee A. Chemoprevention of Diethylnitrosamine-Initiated and Phenobarbital-Promoted Hepatocarcinogenesis in Rats by Sulfated Polysaccharides and Aqueous Extract of Ulva lactuca. Integr Cancer Ther. 2015 Nov; 14(6):525-45. PMID: 26130745.
      View in: PubMed
    22. Tripathi K, Hussein UK, Anupalli R, Barnett R, Bachaboina L, Scalici J, Rocconi RP, Owen LB, Piazza GA, Palle K. Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation. Oncotarget. 2015 Mar 10; 6(7):5237-52. PMID: 25742788.
      View in: PubMed
    23. Gayomali C, Hussein U, Cameron SF, Protopapas Z, Finkelstein FO. Incidence of encapsulating peritoneal sclerosis: a single-center experience with long-term peritoneal dialysis in the United States. Perit Dial Int. 2011 May-Jun; 31(3):279-86. PMID: 21555415.
      View in: PubMed
    24. Selleri S, Arnaboldi F, Palazzo M, Hussein U, Balsari A, Rumio C. Caveolin-1 is expressed on multipotent cells of hair follicles and might be involved in their resistance to chemotherapy. Br J Dermatol. 2005 Sep; 153(3):506-13. PMID: 16120134.
      View in: PubMed
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