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Connection

Susan Smyth to Signal Transduction

This is a "connection" page, showing publications Susan Smyth has written about Signal Transduction.

 
Connection Strength
 
 
 
2.742
 
  1. Smyth SS, Kraemer M, Yang L, Van Hoose P, Morris AJ. Roles for lysophosphatidic acid signaling in vascular development and disease. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 08; 1865(8):158734.
    View in: PubMed
    Score: 0.459
  2. Morris AJ, Smyth SS. Regulation of Lysophosphatidic Acid Metabolism and Signaling by Lipoproteins. Arterioscler Thromb Vasc Biol. 2016 10; 36(10):2029-30.
    View in: PubMed
    Score: 0.358
  3. Smyth SS, Woulfe DS, Weitz JI, Gachet C, Conley PB, Goodman SG, Roe MT, Kuliopulos A, Moliterno DJ, French PA, Steinhubl SR, Becker RC. G-protein-coupled receptors as signaling targets for antiplatelet therapy. Arterioscler Thromb Vasc Biol. 2009 Apr; 29(4):449-57.
    View in: PubMed
    Score: 0.207
  4. Pamuklar Z, Lee JS, Cheng HY, Panchatcharam M, Steinhubl S, Morris AJ, Charnigo R, Smyth SS. Individual heterogeneity in platelet response to lysophosphatidic acid: evidence for a novel inhibitory pathway. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):555-61.
    View in: PubMed
    Score: 0.196
  5. Smyth SS, Sciorra VA, Sigal YJ, Pamuklar Z, Wang Z, Xu Y, Prestwich GD, Morris AJ. Lipid phosphate phosphatases regulate lysophosphatidic acid production and signaling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J Biol Chem. 2003 Oct 31; 278(44):43214-23.
    View in: PubMed
    Score: 0.144
  6. Smyth SS, Patterson C. Tiny dancers: the integrin-growth factor nexus in angiogenic signaling. J Cell Biol. 2002 Jul 08; 158(1):17-21.
    View in: PubMed
    Score: 0.133
  7. Mueller PA, Yang L, Ubele M, Mao G, Brandon J, Vandra J, Nichols TC, Escalante-Alcalde D, Morris AJ, Smyth SS. Coronary Artery Disease Risk-Associated Plpp3 Gene and Its Product Lipid Phosphate Phosphatase 3 Regulate Experimental Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019 11; 39(11):2261-2272.
    View in: PubMed
    Score: 0.110
  8. Abdel-Latif A, Heron PM, Morris AJ, Smyth SS. Lysophospholipids in coronary artery and chronic ischemic heart disease. Curr Opin Lipidol. 2015 Oct; 26(5):432-7.
    View in: PubMed
    Score: 0.083
  9. Mueller P, Ye S, Morris A, Smyth SS. Lysophospholipid mediators in the vasculature. Exp Cell Res. 2015 May 01; 333(2):190-194.
    View in: PubMed
    Score: 0.081
  10. Panchatcharam M, Salous AK, Brandon J, Miriyala S, Wheeler J, Patil P, Sunkara M, Morris AJ, Escalante-Alcalde D, Smyth SS. Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability. Arterioscler Thromb Vasc Biol. 2014 Apr; 34(4):837-45.
    View in: PubMed
    Score: 0.074
  11. Panchatcharam M, Miriyala S, Salous A, Wheeler J, Dong A, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):52-9.
    View in: PubMed
    Score: 0.068
  12. Ren H, Panchatcharam M, Mueller P, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase (LPP3) and vascular development. Biochim Biophys Acta. 2013 Jan; 1831(1):126-32.
    View in: PubMed
    Score: 0.067
  13. Abdel-Latif A, Smyth SS. Preventing platelet thrombosis with a PAR1 pepducin. Circulation. 2012 Jul 03; 126(1):13-5.
    View in: PubMed
    Score: 0.066
  14. Cheng HY, Dong A, Panchatcharam M, Mueller P, Yang F, Li Z, Mills G, Chun J, Morris AJ, Smyth SS. Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. Arterioscler Thromb Vasc Biol. 2012 Jan; 32(1):24-32.
    View in: PubMed
    Score: 0.063
  15. Zhang G, Xiang B, Ye S, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC, Smyth SS, Li Z. Distinct roles for Rap1b protein in platelet secretion and integrin aIIbß3 outside-in signaling. J Biol Chem. 2011 Nov 11; 286(45):39466-77.
    View in: PubMed
    Score: 0.063
  16. Fulkerson Z, Wu T, Sunkara M, Kooi CV, Morris AJ, Smyth SS. Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells. J Biol Chem. 2011 Oct 07; 286(40):34654-63.
    View in: PubMed
    Score: 0.063
  17. Smyth SS. Platelets unplugged: an ATVB special series focused on platelet biology. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2339-40.
    View in: PubMed
    Score: 0.060
  18. Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS. Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. Int J Biochem Cell Biol. 2010 Jun; 42(6):965-74.
    View in: PubMed
    Score: 0.057
  19. Becker RC, Smyth S. The evolution of platelet-directed pharmacotherapy. J Thromb Haemost. 2009 Jul; 7 Suppl 1:266-71.
    View in: PubMed
    Score: 0.054
  20. Morris AJ, Selim S, Salous A, Smyth SS. Blood relatives: dynamic regulation of bioactive lysophosphatidic acid and sphingosine-1-phosphate metabolism in the circulation. Trends Cardiovasc Med. 2009 May; 19(4):135-40.
    View in: PubMed
    Score: 0.053
  21. Totani L, Piccoli A, Manarini S, Federico L, Pecce R, Martelli N, Cerletti C, Piccardoni P, Lowell CA, Smyth SS, Berton G, Evangelista V. Src-family kinases mediate an outside-in signal necessary for beta2 integrins to achieve full activation and sustain firm adhesion of polymorphonuclear leucocytes tethered on E-selectin. Biochem J. 2006 May 15; 396(1):89-98.
    View in: PubMed
    Score: 0.044
  22. Stouffer GA, Smyth SS. Effects of thrombin on interactions between beta3-integrins and extracellular matrix in platelets and vascular cells. Arterioscler Thromb Vasc Biol. 2003 Nov 01; 23(11):1971-8.
    View in: PubMed
    Score: 0.036
  23. Smyth SS. Tweezing apart von Willebrand factor-glycoprotein Ib-IX adhesive signaling. J Thromb Haemost. 2003 Jun; 1(6):1136-7.
    View in: PubMed
    Score: 0.035
  24. Mao G, Smyth SS, Morris AJ. Regulation of PLPP3 gene expression by NF-?B family transcription factors. J Biol Chem. 2019 09 20; 294(38):14009-14019.
    View in: PubMed
    Score: 0.027
  25. Wu C, Lu W, Zhang Y, Zhang G, Shi X, Hisada Y, Grover SP, Zhang X, Li L, Xiang B, Shi J, Li XA, Daugherty A, Smyth SS, Kirchhofer D, Shiroishi T, Shao F, Mackman N, Wei Y, Li Z. Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis. Immunity. 2019 06 18; 50(6):1401-1411.e4.
    View in: PubMed
    Score: 0.027
  26. Totani L, Piccoli A, Dell'Elba G, Concetta A, Di Santo A, Martelli N, Federico L, Pamuklar Z, Smyth SS, Evangelista V. Phosphodiesterase type 4 blockade prevents platelet-mediated neutrophil recruitment at the site of vascular injury. Arterioscler Thromb Vasc Biol. 2014 Aug; 34(8):1689-96.
    View in: PubMed
    Score: 0.019
  27. Park GY, Lee YG, Berdyshev E, Nyenhuis S, Du J, Fu P, Gorshkova IA, Li Y, Chung S, Karpurapu M, Deng J, Ranjan R, Xiao L, Jaffe HA, Corbridge SJ, Kelly EA, Jarjour NN, Chun J, Prestwich GD, Kaffe E, Ninou I, Aidinis V, Morris AJ, Smyth SS, Ackerman SJ, Natarajan V, Christman JW. Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):928-40.
    View in: PubMed
    Score: 0.018
  28. Xiang B, Zhang G, Guo L, Li XA, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nat Commun. 2013; 4:2657.
    View in: PubMed
    Score: 0.017
  29. Xiang B, Zhang G, Ren H, Sunkara M, Morris AJ, Gartner TK, Smyth SS, Li Z. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism. PLoS One. 2012; 7(12):e51037.
    View in: PubMed
    Score: 0.017
  30. Zhao J, He D, Berdyshev E, Zhong M, Salgia R, Morris AJ, Smyth SS, Natarajan V, Zhao Y. Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways. Biochem J. 2011 Oct 01; 439(1):45-55.
    View in: PubMed
    Score: 0.016
  31. Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7257-62.
    View in: PubMed
    Score: 0.014
  32. Federico L, Pamuklar Z, Smyth SS, Morris AJ. Therapeutic potential of autotaxin/lysophospholipase d inhibitors. Curr Drug Targets. 2008 Aug; 9(8):698-708.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.