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Erika Santos Horta

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentNeurology, College of Medicine
DivisionNeurology Faculty
Address501 Jack Stephens Drive
Mail Slot # 500
Little Rock AR 72205
ORCID ORCID Icon0000-0002-6858-0123 Additional info
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    Other Positions
    TitleAssistant Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentInternal Medicine, College of Medicine
    DivisionHematology Oncology

    Collapse Overview 
    Collapse overview
    My mission is to improve the care of patients through developing clinical trials, disseminating knowledge and by listening to my patients experiences.

    Collapse links to outside websites

    Collapse Affiliation 
    Collapse member of
    American Academy of Neurology
    society of neuro-oncology
    Collapse clinical activities
    Neuro-Oncology Clinic Director
    Adult Neurofibromatosis Clinic Director

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Multiple Sclerosis Clinic Director

    Neurofibromatosis Clinic Director

    Brain and spine tumor clinic director

    Collapse education and training
    Henry Ford Hospital, Detroitfellow06/2020Neuro-Oncology
    University of Minnesota, Minneapolisresident06/2018Neurology
    Mayo Clinic, RochesterResearch Fellowship06/2014Neuro-immunology
    Mayo Clinic, RochesterResearch Trainee09/2011Neuro-Immunology
    HCFMRP, Ribeirao Preto Clinical Fellow09/2010Neuro-Immunology
    HCFMRP, Ribeirao PretoResident02/2010Neurology
    USP/RP, Ribeirao PretoMD11/2006Medicine
    UNICAMP, CampinasBachelor01/2000Applied Physics
    Collapse awards and honors
    2012 - 2013McDonald Fellowship, Multiple Sclerosis International Foundation
    2022 - 2024Adult NF Clinic Program Building Pilot Project, Children Tumor Foundation

    Collapse Research 
    Collapse research activities and funding
    MRE grant     (Erika Santos Horta)Sep 16, 2022 - Sep 16, 2023
    Evaluating mitochondrial dysfunction in patients with NF1
    Role Description: Neurofibromatosis type 1 is a common genetic disease with a broad spectrum of clinical manifestations in multiple organs of the body, including the development of tumors and cancers. In animal models of this disease, dysfunction in a part of the cell called mitochondria ,which is responsible for energy production, was seen. This project will study the function of mitochondria in patients with neurofibromatosis through serial blood samples and compare it with people not afflicted by neurofibromatosis. With that, we plan to confirm If there is mitochondrial dysfunction in patients, and if the degree of dysfunction correlates with symptoms like pain and fatigue. Also, we will study if mitochondrial dysfunction is a marker for toxicity of medications like MEK inhibitors that patients with neurofibromatosis type 1 use in a daily basis.
    Role: Principle Investigator

         (Erika Santos Horta)Sep 11, 2022 - Sep 11, 2024
    Children's Tumor Foundation
    UAMS Adult Neurofibromatosis Clinic
    Role Description: The goal of this award is to start an adult clinic for patients with neurofibromatosis.
    Role: Principal Investigator

    CTF     (BIRRER, MICHAEL)Jul 1, 2022 - Jun 30, 2024
    Children's Tumor Foundation
    Adult NF Clinic Program Building Pilot Project
    Role: Principal Investigator

    CTF-2022-12-002     (BIRRER, MICHAEL)Jul 1, 2022 - Jun 30, 2024
    Children's Tumor Foundation
    Adult NF Clinic Program Building Pilot Project
    Role: Principal Investigator

    NRG-BN007     (SANTOS HORTA, ERIKA)Aug 6, 2021 - Aug 5, 2022
    NRG Oncology Foundation
    A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab Versus Temozolomide in Patients With Newly Diagnosed MGMT (Tumor O-6-Methylguanine DNA Methyltransferase) Unmethylated Glioblastoma
    Role: Principal Investigator

    MS700568_0079     (SANTOS HORTA, ERIKA)Dec 12, 2019
    EMD Serono Research & Development Institute
    No FP attached
    Role: Principal Investigator

    MS700568_0078     (SANTOS HORTA, ERIKA)Dec 9, 2019
    EMD Serono Research & Development Institute
    No FP attached
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Battini S, Gokden M, Palys V, Santos Horta E. Diffuse Leptomeningeal Glioneuronal Tumor: First Description of Metastasis to the Lung and Bone Marrow. Cureus. 2023 Nov; 15(11):e48185. PMID: 38050500.
      View in: PubMed
    2. Horta E, Burke-Smith C, Megna B, Nichols K, Vaughn B, Reshi R, Shmidt E. . Prevalence of Cerebrovascular Accidents in Patients with Ulcerative Colitis in a Single Academic Health System . Scientific Reports:. 2022.
    3. Tobias Walbert, Erika Horta . Cancer Metastasis Through the Lymphovascular System Stanley P. Leong, S. David Nathanson, Jonathan S. Zager. Brain Metastases – Current and Future pharmacological treatment. 2022.
    4. Horta E, Bongiorno C, Ezzeddine M, Neil EC. Neurotoxicity of antibodies in cancer therapy: A review. Clin Neurol Neurosurg. 2020 01; 188:105566. PMID: 31731087.
      View in: PubMed
    5. Tobias Walbert Erika S. Horta. Central Nervous System Metastases. Health-Related Quality of Life Related to Toxicity Treatments in Central Nervous System Metastases. 2019.
    6. Flanagan EP, Weinshenker BG, Krecke KN, Lennon VA, Lucchinetti CF, McKeon A, Wingerchuk DM, Shuster EA, Jiao Y, Horta ES, Pittock SJ. Short myelitis lesions in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorders. JAMA Neurol. 2015 Jan; 72(1):81-7. PMID: 25384099.
      View in: PubMed
    7. Horta ES, Lennon VA, Lachance DH, Jenkins SM, Smith CY, McKeon A, Klein C, Pittock SJ. Neural autoantibody clusters aid diagnosis of cancer. Clin Cancer Res. 2014 Jul 15; 20(14):3862-9. PMID: 24833664.
      View in: PubMed
    8. Apiwattanakul M, Asawavichienjinda T, Pulkes T, Tantirittisak T, Hemachudha T, Horta ES, Jenkins SM, Pittock SJ. Diagnostic utility of NMO/AQP4-IgG in evaluating CNS inflammatory disease in Thai patients. J Neurol Sci. 2012 Sep 15; 320(1-2):118-20. PMID: 22831763.
      View in: PubMed
    9. Horta E, McKeon A, Lennon VA, Benarroch EE. Reversible paraneoplastic tonic pupil with PCA-Tr IgG and Hodgkin lymphoma. Neurology. 2012 May 15; 78(20):1620-2. PMID: 22551727.
      View in: PubMed
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