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Jun Ying

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentHealth Biostatistics, College of Public Health
DivisionHealth Biostatistics
Address220 UAMS Campus Dr.
Mail Slot # 781
Little Rock AR 72205
Phone501-526-6734
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    Collapse Affiliation 
    Collapse member of
    AMSTAT
    Cancer Institute

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Director of Biostatistics Shared Resource, Cancer Institute

    Mater of Sciences in Clinical and Translational Sciences Program


    Collapse Teaching 

    Collapse Research 
    Collapse research overview
    1. Submitted Grants from 7/1/2020 to present:

    1.1
    PI: Shuk-mei Ho
    Title: Discovery of Novel Epigenetic Biomarkers Associated with Exposure and Adverse Health Outcomes in Veterans Exposed to Airborne Hazards from Open Burn Pits
    Funding Agency: DoD
    Submission Time: Sept 2020
    Outcome: Not funded

    1.2
    PI: Joseph Su
    Title: Modulation effect of selenium on the association between environmental arsenic exposure and aggressive prostate cancer
    Funding Agency: DoD
    Submission Time: Sept 2020
    Outcome: Not funded

    1.3
    PI: Yuet-Kin Leung
    Title: Regulation of prostate stem-like cells dynamics by lead exposure
    Funding Agency: DoD
    Submission Time: Sept 2020
    Outcome: Not funded

    1.4
    PI: Yuet-Kin Leung
    Title: Epigenetics, heavy metals, and associated disease in Veterans exposed to open burn-pit toxicants
    Funding Agency: VA Merit
    Submission Time: March 2021
    Outcome: Not funded

    1.5
    PI: Michael Birrer
    Title: Novel biomarker modulating angiogenesis/immune response in ovarian cancer pathogenesis
    Funding Agency: NIH/NCI
    Submission Time: Nov 2020
    Outcome: Not funded

    2. Publication from 7/1/2020 to present:
    2.1
    Davis KG, Freeman AM, Ying J, Huth JR. Workers' compensation costs for healthcare caregivers: Home healthcare, long-term care, and hospital nurses and nursing aides.
    Am J Ind Med. 2021 May;64(5):369-380. doi: 10.1002/ajim.23237. Epub 2021 Feb 22.
    PMID: 33616226

    2.2
    Leung YK, Biesiada J, Govindarajah V, Ying J, Kendler A, Medvedovic M, Ho SM. Low-Dose Bisphenol A in a Rat Model of Endometrial Cancer: A CLARITY-BPA Study. Environ Health Perspect. 2020 Dec;128(12):127005. doi: 10.1289/EHP6875. Epub 2020 Dec 9. PubMed PMID: 33296240.

    Collapse research activities and funding
    2UM1CA121947     (Sparano/Lee)Sep 1, 2020 - Aug 31, 2025
    NIH/NCI/Montefiore/EMMES
    AIDS MALIGNANCY CONSORTIUM (AMC)
    Role Description: The goal of this project is to continue and expand our domestic and international clinical trials work in these areas, including the ANCHOR trial. The Statistical Center for AIDS Malignancy Consortium (AMC) supports the statistical design and analysis of the multicenter clinical trials and studies conducted by the AMC, and the development and implementation of the ANCHOR study.
    Role: Other

    1UL1 TR003107     (James)Jul 1, 2019 - Jun 30, 2024
    NIH/NCATS
    EXPANDING TRANSLATIONAL RESEARCH IN ARKANSAS
    Role Description: As the academic home for translational researchers, our Clinical and Translational Science Award (CTSA) hub has developed efficient and resourceful workflows, established excellent research training and educational programs, and launched initiatives to support the growth of team science and community engagement. The major goal of this project is to expand Translational Research in Arkansas
    Role: Other

    U01DD001285-03     (Nembhard)Dec 1, 2018 - Aug 31, 2023
    DHHS/CDC
    BIRTH DEFECTS STUDY TO EVALUATE PREGNANCY EXPOSURES (BD-STEPS) II
    Role Description: The Arkansas Center for Birth Defects Research and Prevention, a participant in the NBDPS for 16 years and a participant in 8D STEPS I, is dedicated to understanding the causes of birth defects and welcomes the opportunity to continue to contribute to an evidence base that will facilitate development of effective prevention strategies. The goal of this project is to evaluate pregnancy exposures (BD-STEPS) II Core & Component B Steps – Stillbirth
    Role: Other

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
    List All   |   Timeline
    1. Sun F, Cheng Y, Ying J, Mery D, Al Hadidi S, Wanchai V, Siegel ER, Xu H, Gai D, Ashby TC, Bailey C, Chen JR, Schinke C, Thanendrarajan S, Zangari M, Janz S, Barlogie B, Van Rhee F, Tricot G, Shaughnessy JD, Zhan F. A gene signature can predict risk of MGUS progressing to multiple myeloma. J Hematol Oncol. 2023 Jun 29; 16(1):70. PMID: 37386588.
      View in: PubMed
    2. Nissen C, Ying J, Newkirk M, Narayanasamy G, Lewis G, Xia F. An Analysis of Risk Factors for Radiation Necrosis Following Cranial Radiation. Cureus. 2022 Sep; 14(9):e29268. PMID: 36133504.
      View in: PubMed
    3. Li C, Bhatti SA, Ying J. Immune Checkpoint Inhibitors-Associated Cardiotoxicity. Cancers (Basel). 2022 Feb 23; 14(5). PMID: 35267453.
      View in: PubMed
    4. Ho SM, Rao R, Ouyang B, Tam NNC, Schoch E, Song D, Ying J, Leung YK, Govindarajah V, Tarapore P. Three-Generation Study of Male Rats Gestationally Exposed to High Butterfat and Bisphenol A: Impaired Spermatogenesis, Penetrance with Reduced Severity. Nutrients. 2021 Oct 17; 13(10). PMID: 34684636.
      View in: PubMed
    5. Leung YK, Biesiada J, Govindarajah V, Ying J, Kendler A, Medvedovic M, Ho SM. Low-Dose Bisphenol A in a Rat Model of Endometrial Cancer: A CLARITY-BPA Study. Environ Health Perspect. 2020 12; 128(12):127005. PMID: 33296240.
      View in: PubMed
    6. Cheong A, Johnson SA, Howald EC, Ellersieck MR, Camacho L, Lewis SM, Vanlandingham MM, Ying J, Ho SM, Rosenfeld CS. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. 2018; 13(7):704-720. PMID: 30001178.
      View in: PubMed
    7. Leung YK, Ouyang B, Niu L, Xie C, Ying J, Medvedovic M, Chen A, Weihe P, Valvi D, Grandjean P, Ho SM. Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. Epigenetics. 2018; 13(3):290-300. PMID: 29560787.
      View in: PubMed
    8. Chen G, Zhang Y, Yuan M, He S, Ying J, Li C. [Effect of simulated microgravity on peripheral oxygen saturation in rats]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 02 25; 35(1):57-59. PMID: 29745601.
      View in: PubMed
    9. Leung YK, Govindarajah V, Cheong A, Veevers J, Song D, Gear R, Zhu X, Ying J, Kendler A, Medvedovic M, Belcher S, Ho SM. Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk. Endocr Relat Cancer. 2017 07; 24(7):365-378. PMID: 28487351.
      View in: PubMed
    10. Tarapore P, Hennessy M, Song D, Ying J, Ouyang B, Govindarajah V, Leung YK, Ho SM. Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets. Data Brief. 2016 Dec; 9:812-817. PMID: 27872877.
      View in: PubMed
    11. Tarapore P, Hennessy M, Song D, Ying J, Ouyang B, Govindarajah V, Leung YK, Ho SM. High butter-fat diet and bisphenol A additively impair male rat spermatogenesis. Reprod Toxicol. 2017 03; 68:191-199. PMID: 27658648.
      View in: PubMed
    12. Zhou L, Xu T, Zhang Y, Zhu M, Zhu W, Wang Z, Gu H, Wang H, Li P, Ying J, Yang L, Ren P, Li J, Xu Z, Ni L, Bao Q, Chen J. Transcriptional network in ovarian cancer cell line SKOV3 treated with Pinellia pedatisecta Schott extract. Oncol Rep. 2016 Jul; 36(1):462-70. PMID: 27176137.
      View in: PubMed
    13. Govindarajah V, Leung YK, Ying J, Gear R, Bornschein RL, Medvedovic M, Ho SM. In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands. J Nutr Biochem. 2016 Mar; 29:73-82. PMID: 26895667.
      View in: PubMed
    14. Martinez AM, Cheong A, Ying J, Xue J, Kannan K, Leung YK, Thomas MA, Ho SM. Effects of High-Butterfat Diet on Embryo Implantation in Female Rats Exposed to Bisphenol A. Biol Reprod. 2015 Dec; 93(6):147. PMID: 26510865.
      View in: PubMed
    15. Paquette IM, Ying J, Shah SA, Abbott DE, Ho SM. African Americans should be screened at an earlier age for colorectal cancer. Gastrointest Endosc. 2015 Nov; 82(5):878-83. PMID: 25952088.
      View in: PubMed
    16. Lam HM, Ouyang B, Chen J, Ying J, Wang J, Wu CL, Jia L, Medvedovic M, Vessella RL, Ho SM. Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer. Endocr Relat Cancer. 2014; 21(6):903-14. PMID: 25287069.
      View in: PubMed
    17. Tarapore P, Ying J, Ouyang B, Burke B, Bracken B, Ho SM. Exposure to bisphenol A correlates with early-onset prostate cancer and promotes centrosome amplification and anchorage-independent growth in vitro. PLoS One. 2014; 9(3):e90332. PMID: 24594937.
      View in: PubMed
    18. Ouyang B, Bernstein DI, Lummus ZL, Ying J, Boulet LP, Cartier A, Gautrin D, Ho SM. Interferon-? promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma. Toxicol Sci. 2013 Jun; 133(2):218-24. PMID: 23535363.
      View in: PubMed
    19. Winchester PD, Huskins J, Ying J. Agrichemicals in surface water and birth defects in the United States. Acta Paediatr. 2009 Apr; 98(4):664-9. PMID: 19183116.
      View in: PubMed
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