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Emmanouil Giorgakis

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentSurgery, College of Medicine
DivisionSurgery Transplant
Address324 UAMS Campus Dr.
Mail Slot # 520-4
Little Rock AR 72205
ORCID ORCID Icon0000000250195497 Additional info
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    Collapse Overview 

    Collapse Affiliation 
    Collapse member of
    ASTS
    ESOT
    TTS
    ILTS
    ELITA
    RCS(Ed)
    RCPS(Glas)- Fellow
    EBS(transplant)- Fellow
    ACS-Ass.Fellow
    Collapse collaborator
    HOPE-In-Action Consortium
    CovidSurg Collaborative
    GlobalSurg Collaborative
    Mayo Clinic Arizona
    J Hopkins
    King's College London
    UHN-Toronto
    Livergroup
    Pancreasgroup
    CERO-19
    Collapse clinical activities
    Liver transplantation
    Kidney transplantation ( adult/ pediatric)
    Hepatobiliary and Pancreatic Surgery

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Quality Medical Officer- Transplant Service Line


    Collapse Research 
    Collapse research overview
    Dr. Giorgakis’ research interests focus on donation after circulatory death liver transplantation, machine preservation technologies, and expedited utilization of marginal grafts; transplant oncology; transplant healthcare quality improvement projects; and comparative analysis of large scale national databases.

    Dr. Giorgakis is the lead local investigator in multiple multicenter and international projects, including the HOPE in Action liver and kidney trials for the use of HIV+ organs on HIV+ recipients sponsored by J Hopkins/ NIAID, the international cohort study on liver transplantation on cirrhotics with early intrahepatic cholangiocarcinoma, the CovidSurg and CovidSurg-Cancer studies supported by the Global Surgery Collaborative/NIHR, the Liver Group, the International COVID-19 Solid Organ Transplant Registry, and the International CERO-19 Project.

    Collapse research activities and funding
    AWD00054674     (Emmanouil Giorgakis)Sep 22, 2020 - Sep 21, 2022
    University Health Network, Canada
    Liver Transplantation for the treatment of early stages of intrahepatic cholangiocarcinoma in cirrhotics. A multicenter, phase II, open-label study of adults with end-stage liver disease and “very early” iCCA.
    Role: Principal Investigator
    U01AI134591     (GIORGAKIS, EMMANOUIL)Feb 5, 2020
    NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Johns Hopkins University
    HOPE in Action Prospective Multicenter, Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients (IRB 239700)
    Role: Principal Investigator
    U01AI138897     (GIORGAKIS, EMMANOUIL)Feb 5, 2020
    NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: Johns Hopkins University
    HOPE in Action Prospective Multicenter, Clinical Trial of HIV+ Deceased Donor Liver Transplants for HIV+ Recipients (IRB 239701)
    Role: Principal Investigator

    Collapse Outreach 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Khorsandi SE, Hardgrave HJ, Osborn T, Klutts G, Nigh J, Spencer-Cole RT, Kakos CD, Anastasiou I, Mavros MN, Giorgakis E. Artificial Intelligence in Liver Transplantation. Transplant Proc. 2021 Nov 02. PMID: 34740449.
      View in: PubMed
    2. Giorgakis E, Khorsandi SE, Burdine L, Singer A, Hewitt W, Heaton N, Mathur AK. Centre volume impact on graft survival and waiting list time in donation after circulatory death liver transplantation in the USA. Br J Surg. 2021 Oct 21. PMID: 34672324.
      View in: PubMed
    3. SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Sep 27; 108(9):1056-1063. PMID: 33761533.
      View in: PubMed
    4. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2021 Aug 24. PMID: 34428858.
      View in: PubMed
    5. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021 11; 76(11):1454-1464. PMID: 34371522.
      View in: PubMed
    6. Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score. Br J Surg. 2021 Jul 06. PMID: 34227657.
      View in: PubMed
    7. Perisetti A, Goyal H, Yendala R, Thandassery RB, Giorgakis E. Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements. World J Gastroenterol. 2021 Jun 28; 27(24):3466-3482. PMID: 34239263.
      View in: PubMed
    8. Esagian SM, Kakos CD, Giorgakis E, Burdine L, Barreto JC, Mavros MN. Adjuvant Transarterial Chemoembolization Following Curative-Intent Hepatectomy Versus Hepatectomy Alone for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Cancers (Basel). 2021 Jun 15; 13(12). PMID: 34203692.
      View in: PubMed
    9. Hill SEM, Jensen HK, Reif R, Karim SA, Sexton KW, Kalkwarf KJ, Giorgakis E, Burdine L. National Readmissions Database characterization of post-cholecystectomy care for inpatients: Readmissions and bile duct repair. Am J Surg. 2021 May 21. PMID: 34176599.
      View in: PubMed
    10. Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study. J Thorac Cardiovasc Surg. 2021 08; 162(2):e355-e372. PMID: 33933259.
      View in: PubMed
    11. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 06; 76(6):748-758. PMID: 33690889.
      View in: PubMed
    12. Stephenson K, Kalkwarf K, Giorgakis E. Application of resuscitative endovascular balloon occlusion in post-transplant mycotic hepatic artery pseudoaneurysm rupture in the setting of Aspergillus Constellatus bacteremia. Ann Hepatobiliary Pancreat Surg. 2021 Feb 28; 25(1):126-131. PMID: 33649265.
      View in: PubMed
    13. Muñoz-Martínez S, Sapena V, Forner A, Nault JC, Sapisochin G, Rimassa L, Sangro B, Bruix J, Sanduzzi-Zamparelli M, Holówko W, El Kassas M, Mocan T, Bouattour M, Merle P, Hoogwater FJH, Alqahtani SA, Reeves HL, Pinato DJ, Giorgakis E, Meyer T, Villadsen GE, Wege H, Salati M, Mínguez B, Di Costanzo GG, Roderburg C, Tacke F, Varela M, Galle PR, Alvares-da-Silva MR, Trojan J, Bridgewater J, Cabibbo G, Toso C, Lachenmayer A, Casadei-Gardini A, Toyoda H, Lüdde T, Villani R, Matilla Peña AM, Guedes Leal CR, Ronzoni M, Delgado M, Perelló C, Pascual S, Lledó JL, Argemi J, Basu B, da Fonseca L, Acevedo J, Siebenhüner AR, Braconi C, Meyers BM, Granito A, Sala M, Rodríguez-Lope C, Blaise L, Romero-Gómez M, Piñero F, Gomez D, Mello V, Pinheiro Alves RC, França A, Branco F, Brandi G, Pereira G, Coll S, Guarino M, Benítez C, Anders MM, Bandi JC, Vergara M, Calvo M, Peck-Radosavljevic M, García-Juárez I, Cardinale V, Lozano M, Gambato M, Okolicsanyi S, Morales-Arraez D, Elvevi A, Muñoz AE, Lué A, Iavarone M, Reig M. Assessing the impact of COVID-19 on liver cancer management (CERO-19). JHEP Rep. 2021 Jun; 3(3):100260. PMID: 33644725.
      View in: PubMed
    14. Giorgakis E, Khorsandi SE, Mathur AK, Burdine L, Jassem W, Heaton N. Comparable graft survival is achievable with the usage of donation after circulatory death liver grafts from donors at or above 70 years of age: A long-term UK national analysis. Am J Transplant. 2021 06; 21(6):2200-2210. PMID: 33222386.
      View in: PubMed
    15. Giorgakis E, Mathur AK. Expedited placement to maximize utilization of marginal organs. Curr Opin Organ Transplant. 2020 12; 25(6):640-646. PMID: 33105204.
      View in: PubMed
    16. C4 article: Implications of COVID-19 in transplantation. Am J Transplant. 2021 05; 21(5):1801-1815. PMID: 33040483.
      View in: PubMed
    17. Sheckley M, Calderon E, Patel BM, Sen A, Giorgakis E, Hewitt WR, Singer AL, Reddy KS, Moss AA, Mathur AK. Utilization of Veno-Arterial Extracorporeal Life Support for Acute Respiratory Distress Syndrome After Liver Transplant. Exp Clin Transplant. 2020 Aug 07. PMID: 32778014.
      View in: PubMed
    18. Kakadia S, Trotta H, Kurczek L, Burdine L, Veeraputhiran M, Giorgakis E. Early Outcomes of Ruxolitinib in the Treatment of Steroid Refractory Graft-versus-host Disease on Liver Transplant Recipients. Transplantation. 2020 08; 104(8):e247. PMID: 32732859.
      View in: PubMed
    19. Giorgakis E, Zehtaban SP, Stevens AE, Bhusal S, Burdine L. COVID-19 in solid organ transplant recipients. Transpl Infect Dis. 2021 02; 23(1):e13419. PMID: 32667723.
      View in: PubMed
    20. Calderon E, Chang YH, Chang JM, Velazco CS, Giorgakis E, Srinivasan A, Moss AA, Khamash H, Heilman R, Reddy KS, Mathur AK. Outcomes and Health Care Utilization After Early Hospital Dismissal in Kidney Transplantation: An Analysis of 1001 Consecutive Cases. Ann Surg. 2020 Jun 09. PMID: 32516231.
      View in: PubMed
    21. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. Lancet. 2020 07 04; 396(10243):27-38. PMID: 32479829.
      View in: PubMed
    22. Perisetti A, Inamdar S, Garcia-Saenz-de-Sicilia, Giorgakis E. Abnormal liver enzymes in a liver transplant recipient. American Journal of Transplantation. 2020; 1932-1934.
      View Publication
    23. Giorgakis E, Chong B, Oklu R, Jaroszewski DE, Knuttinen G, Mathur AK. Successful treatment of visceral pseudoaneurysm after pancreatectomy using flow-diverting stent device. Ann Hepatobiliary Pancreat Surg. 2020 Feb; 24(1):114-118. PMID: 32181440.
      View in: PubMed
    24. C4 article: Challenges and solutions to appropriate and timely medication access in transplantation in the United States. Am J Transplant. 2020 02; 20(2):362-376. PMID: 31814278.
      View in: PubMed
    25. Emmanouil Giorgakis, Amit K Mathur. Handbook of Gastrointestinal Cancers: Evidence-Based Treatment and Multidisciplinary Patient Care, Springer Publishing Company Tanios Bekaii-Saab, Bassel F El-Rayes, Timothy M Pawlik . How I Treat Early-Stage Hepatocellular Cancer Through Transplant. 2019.
    26. Khurmi N, Seman M, Gaitan B, Young S, Rosenfeld D, Giorgakis E, Hewitt W, Mathur A. Nontraditional Use of TEE to Evaluate Hepatic Vasculature and Guide Surgical Management in Orthotopic Liver Transplantation. Case Rep Transplant. 2019; 2019:5293069. PMID: 31321114.
      View in: PubMed
    27. Rosenfeld DM, Smith ML, Seamans DP, Giorgakis E, Gaitan BD, Khurmi N, Aqel BA, Reddy KS. Fatal diffuse pulmonary fat microemboli following reperfusion in liver transplantation with the use of marginal steatotic allografts. Am J Transplant. 2019 09; 19(9):2640-2645. PMID: 31012531.
      View in: PubMed
    28. Giorgakis E, Mathur AK, Chakkera HA, Reddy KS, Moss AA, Singer AL. Solid pancreas transplant: Pushing forward. World J Transplant. 2018 Nov 30; 8(7):237-251. PMID: 30596031.
      View in: PubMed
    29. Giorgakis E, Singer AL, Khorsandi SE, Prachalias A. Transplantation crisis at the time of economic recession in Greece. Public Health. 2018 Jul; 160:125-128. PMID: 29803187.
      View in: PubMed
    30. Giorgakis E, Khorsandi SE, Jassem W, Heaton N. DCD consensus and futility in liver transplantation. J Hepatol. 2018 07; 69(1):255-256. PMID: 29655976.
      View in: PubMed
    31. Giorgakis E, Tedeschi M, Bonaccorsi-Riani E, Khorsandi SE, Menon K, Vilca-Melendez H, Jassem W, Srinivasan P, Prachalias A, Heaton N. The Effect of Recipient Body Mass Index and Its Extremes on Survival and Graft Vascular and Biliary Complications After Liver Transplantation: A Single Center Retrospective Study. Ann Transplant. 2017 Oct 13; 22:611-621. PMID: 29026064.
      View in: PubMed
    32. Giorgakis E, Khorsandi SE, Jassem W, Heaton N. Minimization of Ischemic Cholangiopathy in Donation After Cardiac Death Liver Transplantation: Is It Thrombolytic Therapy or Warm Ischemic Time Stringency and Donor Bile Duct Flush? Am J Transplant. 2018 01; 18(1):274-275. PMID: 28710889.
      View in: PubMed
    33. Khorsandi SE, Giorgakis E, Vilca-Melendez H, O'Grady J, Heneghan M, Aluvihare V, Suddle A, Agarwal K, Menon K, Prachalias A, Srinivasan P, Rela M, Jassem W, Heaton N. Developing a donation after cardiac death risk index for adult and pediatric liver transplantation. World J Transplant. 2017 Jun 24; 7(3):203-212. PMID: 28698837.
      View in: PubMed
    34. Giorgakis E, Tedeschi M, Bonaccorsi-Riani E, Khorsandi SE, Vilca-Melendez H, Heaton N. Primum Non Nocere: Organ Donation After Electrocution and Transplantation of Electricity-Damaged Livers: Report of 2 Cases. Transplant Proc. 2016 10; 48(8):2596-2600. PMID: 27788788.
      View in: PubMed
    35. Ramesh BS, Giorgakis E, Lopez-Davila V, Dashtarzheneha AK, Loizidou M. Detection of cell surface calreticulin as a potential cancer biomarker using near-infrared emitting gold nanoclusters. Nanotechnology. 2016 Jul 15; 27(28):285101. PMID: 27255548.
      View in: PubMed
    36. Giorgakis E, Ramesh B, Kamali-Dashtarzheneh A, Fusai GK, Imber C, Tsironis D, Loizidou M. Demonstration of Calreticulin Expression in Hamster Pancreatic Adenocarcinoma with the Use of Fluorescent Gold Quantum Dots. Anticancer Res. 2016 Mar; 36(3):861-7. PMID: 26976972.
      View in: PubMed
    37. Giorgakis E, Ramesh B, Loizidou M. Ex vivo tracing of pancreatic neuroendocrine tumors with bio-conjugated fluorescent quantum dots: a paradigm of nanoparticle-based diagnostics. Ann Gastroenterol. 2015 Oct-Dec; 28(4):509-10. PMID: 26423638.
      View in: PubMed
    38. Chakravartty S, Tassinari D, Salerno A, Giorgakis E, Rubino F. What is the Mechanism Behind Weight Loss Maintenance with Gastric Bypass? Curr Obes Rep. 2015 Jun; 4(2):262-8. PMID: 26627220.
      View in: PubMed
    39. Giorgakis E, Loizidou M, Mavroeidis V, Imber C, Ramesh B. Fluorescence-guided laparoscopic surgery: what if we could label pancreatic cancer with biomarker-conjugated fluorescent quantum nanocrystals? J Am Coll Surg. 2015 Mar; 220(3):376-7. PMID: 25700907.
      View in: PubMed
    40. Giorgakis E. ESSENTIAL SKILLS IN THE MANAGEMENT OF SURGICAL PATIENT-ESMSC 2. Athens: Scientific Publications Parisianou S.A. Abdominal Organ Transplantation: Essential Principles. 2015; 91-95.
    41. Panagiotopoulos S, Giorgakis E, Rubino F. ESSENTIAL SKILLS IN THE MANAGEMENT OF SURGICAL PATIENT-ESMSC 2. Athens: Scientific Publications Parisianou S.A. Bariatric, Metabolic and Diabetes Surgery: Essential Principles. 2015; 148-152.
    42. Giorgakis E, Mavroeidis V, Tsironis D, Davidson B. Vascular endothelial growth factor detection in serous pancreatic cysts: have we really reached a breakthrough? J Am Coll Surg. 2014 Sep; 219(3):591. PMID: 25151348.
      View in: PubMed
    43. Giorgakis E, Fernandez-Diaz S. Diffuse subcutaneous emphysema after transperitoneal laparoscopic donor nephrectomy. Hippokratia. 2013 Jan; 17(1):94. PMID: 23935356.
      View in: PubMed
    44. Kourkoulos M, Giorgakis E, Nikiteas N, Tsigris C. Laparoscopic Gastric Plication: Its pitfalls and intrigues. Hippokratia. 2012 Oct; 16(4):392. PMID: 23935334.
      View in: PubMed
    45. Kourkoulos M, Giorgakis E, Kokkinos C, Mavromatis T, Griniatsos J, Nikiteas N, Tsigris C. Laparoscopic gastric plication for the treatment of morbid obesity: a review. Minim Invasive Surg. 2012; 2012:696348. PMID: 22811900.
      View in: PubMed
    46. Giorgakis E, Karydakis V, Farghaly A. Perforated endometrial appendicitis in pregnancy. Hippokratia. 2012 Apr; 16(2):181-3. PMID: 23935277.
      View in: PubMed
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