Samantha Kendrick
Title | Associate Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Biochemistry & Molecular Biology, College of Medicine |
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Address | 4104 Outpatient Circle Mail Slot # 516 Little Rock AR 72205
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Phone | 501-526-6000 |
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ORCID
| 0000-0002-7782-7415 |
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vCard | Download vCard |
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Title | Associate Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Pathology, College of Medicine |
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Affiliation American Society of Hematology The G4 Society
Biography Director, Summer Undergraduate Research Program (SURF)
2023 | Outstanding Mentor Award, Graduate School, UAMS | 2023 | Red Sash Honoree, College of Medicine, UAMS |
Research 2341253 (EOFF, ROBERT L)May 1, 2024 - Apr 30, 2028 National Science Foundation Replication of G-quadruplex DNA by translesion polymerases Role: Principal Investigator |
| CA210788 (KENDRICK, SAMANTHA)Sep 15, 2022 - Sep 14, 2025 DoD Targeting unique DNA structures to repress oncogenic signaling in lymphoma Role: Principal Investigator |
| W81XWH 22 1 1031 (KENDRICK, SAMANTHA)Sep 15, 2022 - Sep 14, 2025 US Department of Defense Targeting unique DNA structures to repress oncogenic signaling in lymphoma Role: Principal Investigator |
| W81XWH2211031 (KENDRICK, SAMANTHA)Sep 15, 2022 - Sep 14, 2025 US Department of Defense Targeting unique DNA structures to repress oncogenic signaling in lymphoma Role: Principal Investigator |
| P20GM121293 (TACKETT, ALAN)Jul 1, 2020 - Jun 30, 2022 NIH/NIGMS Targeting oncogenic regulation through unique DNA structures in lymphoma Role: Principal Investigator |
| P20GM203635 (SMELTZER, MARK)May 1, 2019 - Apr 30, 2020 NIH/NIGMS Impact of HIV on lymphomagenesis Role: Principal Investigator |
| Seeds of Science FY19 (BYRD, ALICIA K)Feb 1, 2019 - Jan 31, 2020 UAMS Internal Research Awards Seeds of Science Pilot award Role: Principal Investigator |
| ACRI # 037191 (KENDRICK, SAMANTHA)Jul 1, 2018 - Jun 30, 2019 UAMS ACHRI Flow Through No FP attached Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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McCrury M, Swafford K, Shuttleworth SL, Mehdi SH, Acharya B, Saha D, Naceanceno K, Byrum SD, Storey AJ, Xu YZ, Doshier C, Patel V, Post GR, De Loose A, Rodriguez A, Shultz LD, Zhan F, Yoon D, Frett B, Kendrick S. Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma. Mol Cancer Ther. 2024 Mar 04; 23(3):316-329. PMID: 37816504.
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Chen J, Wang Z, Phuc T, Xu Z, Yang D, Chen Z, Lin Z, Kendrick S, Dai L, Li HY, Qin Z. Oncolytic strategy using new bifunctional HDACs/BRD4 inhibitors against virus-associated lymphomas. PLoS Pathog. 2023 01; 19(1):e1011089. PMID: 36638143.
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Swafford K, Acharya B, Xu YZ, Raney T, McCrury M, Saha D, Frett B, Kendrick S. Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group. Genes (Basel). 2022 06 25; 13(7). PMID: 35885931.
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Chen J, Barrett L, Lin Z, Kendrick S, Mu S, Dai L, Qin Z. Identification of natural compounds tubercidin and lycorine HCl against small-cell lung cancer and BCAT1 as a therapeutic target. J Cell Mol Med. 2022 05; 26(9):2557-2565. PMID: 35318805.
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Mohan M, Kendrick S, Szabo A, Yarlagadda N, Atwal D, Pandey Y, Roy A, Parikh R, Lopez J, Thanendrarajan S, Schinke C, Alapat D, Sawyer J, Tian E, Tricot G, van Rhee F, Zangari M. Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma. Blood Adv. 2022 02 08; 6(3):808-817. PMID: 34807986.
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Chen J, Dai L, Kendrick S, Post SR, Qin Z. The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrob Agents Chemother. 2022 03 15; 66(3):e0239521. PMID: 35041508.
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Mohan M, Szabo A, Yarlagadda N, Gundarlapalli S, Thanendrarajan S, Kendrick S, Schinke C, Alapat D, Sawyer J, Tian E, Tricot G, van Rhee F, Zangari M. Persistent bone marrow minimal residual disease as a "high-risk" disease feature in multiple myeloma. Am J Hematol. 2021 09 01; 96(9):E341-E344. PMID: 34050985.
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Mohan M, Kumar M, Samant R, Van Hemert R, Tian E, Desai S, van Rhee F, Thanendrarajan S, Schinke C, Suva LJ, Sharma S, Milad M, Kendrick S, Zangari M. Bone remineralization of lytic lesions in multiple myeloma - The Arkansas experience. Bone. 2021 05; 146:115876. PMID: 33556629.
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Brown SL, Kendrick S. The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure. Pharmaceuticals (Basel). 2021 Jan 27; 14(2). PMID: 33513764.
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Shponka V, Reveles CY, Alam S, Jaramillo M, Maguire A, Rimsza LM, Kendrick S. Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV. AIDS. 2020 11 15; 34(14):2025-2035. PMID: 32773475.
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Xu YZ, Jenjaroenpun P, Wongsurawat T, Byrum SD, Shponka V, Tannahill D, Chavez EA, Hung SS, Steidl C, Balasubramanian S, Rimsza LM, Kendrick S. Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma. NAR Cancer. 2020 Dec; 2(4):zcaa029. PMID: 33094287.
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Storey AJ, Naceanceno KS, Lan RS, Washam CL, Orr LM, Mackintosh SG, Tackett AJ, Edmondson RD, Wang Z, Li HY, Frett B, Kendrick S, Byrum SD. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Mol Omics. 2020 08 01; 16(4):316-326. PMID: 32347222.
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Chen J, Kendrick S, Qin Z. Mechanistic Insights into Chemoresistance Mediated by Oncogenic Viruses in Lymphomas. Viruses. 2019 12 16; 11(12). PMID: 31888174.
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Maguire A, Chen X, Wisner L, Malasi S, Ramsower C, Kendrick S, Barrett MT, Glinsmann-Gibson B, McGrath M, Rimsza LM. Enhanced DNA repair and genomic stability identify a novel HIV-related diffuse large B-cell lymphoma signature. Int J Cancer. 2019 12 01; 145(11):3078-3088. PMID: 31044434.
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Saha D, Kharbanda A, Essien , Zhang , Cooper R, Basak D, Kendrick S, Frett B, Li H. Intramolecular cyclization of imidazo[1,2-a]pyridines via a silver mediated/palladium catalyzed C–H activation strategy. Organic chemistry frontiers. 2019; 2234.
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Kendrick S, Muranyi A, Gokhale V, Hurley LH, Rimsza LM. Simultaneous Drug Targeting of the Promoter MYC G-Quadruplex and BCL2 i-Motif in Diffuse Large B-Cell Lymphoma Delays Tumor Growth. J Med Chem. 2017 08 10; 60(15):6587-6597. PMID: 28605593.
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Kendrick S, Rimsza LM, Scott DW, Slack GW, Farinha P, Tan KL, Persky D, Puvvada S, Connors JM, Sehn L, Gascoyne RD, Schmelz M. Aberrant cytoplasmic expression of MHCII confers worse progression free survival in diffuse large B-cell lymphoma. Virchows Arch. 2017 Jan; 470(1):113-117. PMID: 27888357.
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Kendrick S, Tus K, Wright G, Jaffe ES, Rosenwald A, Campo E, Chan WC, Connors JM, Braziel RM, Ott G, Delabie J, Cook JR, Weisenburger DD, Greiner TC, Fu K, Staudt LM, Gascoyne RD, Scott DW, Rimsza LM. Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status. Leuk Lymphoma. 2016; 57(3):717-20. PMID: 26437080.
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Li L, Pongtornpipat P, Tiutan T, Kendrick SL, Park S, Persky DO, Rimsza LM, Puvvada SD, Schatz JH. Synergistic induction of apoptosis in high-risk DLBCL by BCL2 inhibition with ABT-199 combined with pharmacologic loss of MCL1. Leukemia. 2015 Aug; 29(8):1702-12. PMID: 25882699.
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Kendrick SL, Redd L, Muranyi A, Henricksen LA, Stanislaw S, Smith LM, Perry AM, Fu K, Weisenburger DD, Rosenwald A, Ott G, Gascoyne RD, Jaffe ES, Campo E, Delabie J, Braziel RM, Cook JR, Tubbs RR, Staudt LM, Chan WC, Steidl C, Grogan TM, Rimsza LM. BCL2 antibodies targeted at different epitopes detect varying levels of protein expression and correlate with frequent gene amplification in diffuse large B-cell lymphoma. Hum Pathol. 2014 Oct; 45(10):2144-53. PMID: 25090918.
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Kendrick S, Kang HJ, Alam MP, Madathil MM, Agrawal P, Gokhale V, Yang D, Hecht SM, Hurley LH. The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure. J Am Chem Soc. 2014 Mar 19; 136(11):4161-71. PMID: 24559410.
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Kang HJ, Kendrick S, Hecht SM, Hurley LH. The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules. J Am Chem Soc. 2014 Mar 19; 136(11):4172-85. PMID: 24559432.
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Puvvada S, Kendrick S, Rimsza L. Molecular classification, pathway addiction, and therapeutic targeting in diffuse large B cell lymphoma. Cancer Genet. 2013 Jul-Aug; 206(7-8):257-65. PMID: 24080457.
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Valentino C, Kendrick S, Johnson N, Gascoyne R, Chan WC, Weisenburger D, Braziel R, Cook JR, Tubbs R, Campo E, Rosenwald A, Ott G, Delabie J, Jaffe E, Zhang W, Brunhoeber P, Nitta H, Grogan T, Rimsza L. Colorimetric in situ hybridization identifies MYC gene signal clusters correlating with increased copy number, mRNA, and protein in diffuse large B-cell lymphoma. Am J Clin Pathol. 2013 Feb; 139(2):242-54. PMID: 23355209.
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Wang L, Rodrigues NA, Wu Y, Maslikowski BM, Singh N, Lacroix S, B?dard PA. Pleiotropic action of AP-1 in v-Src-transformed cells. J Virol. 2011 Jul; 85(13):6725-35. PMID: 21507983.
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Brooks TA, Kendrick S, Hurley L. Making sense of G-quadruplex and i-motif functions in oncogene promoters. FEBS J. 2010 Sep; 277(17):3459-69. PMID: 20670278.
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Kendrick S, Hurley LH. The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements. Pure Appl Chem. 2010 Jan 01; 82(8):1609-1621. PMID: 21796223.
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Kendrick S, Akiyama Y, Hecht SM, Hurley LH. The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern. J Am Chem Soc. 2009 Dec 09; 131(48):17667-76. PMID: 19908860.
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Richardson M, Wong D, Lacroix S, Stanisz J, Singh G. Inhibition by doxycycline of angiogenesis in the chicken chorioallantoic membrane (CAM). Cancer Chemother Pharmacol. 2005 Jul; 56(1):1-9. PMID: 15726364.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2005 | 1 | 2009 | 1 | 2010 | 2 | 2011 | 1 | 2013 | 2 | 2014 | 3 | 2015 | 2 | 2016 | 1 | 2017 | 1 | 2019 | 3 | 2020 | 3 | 2021 | 3 | 2022 | 4 | 2023 | 1 | 2024 | 1 |
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