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Clark Sims

TitleAssistant Staff Scientist
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPediatrics, College of Medicine
DivisionPeds Developmental Nutrition
Address Behavorial Medicine Building
4301 W Markham St.
Mail Slot # 611
Little Rock AR 72205
Phone501-686-7146
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    Collapse Research 
    Collapse research activities and funding
    F31DK104533     (SIMS, CLARK RANEY)Jan 1, 2015 - Dec 31, 2017
    NIH
    Targeting renal perfusion and mitochondrial oxidants in a model of infant sepsis
    Role: Principal Investigator
    14PRE20450050     (SIMS, CLARK R)Jul 1, 2014 - Dec 31, 2014
    American Heart Association (SouthWest Affiliate)
    Renal microcirculatory failure in a rat pup model of pediatric sepsis
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Ballard M, Saben JL, Krukowski RA, B?rsheim E, Sims CR, Samuel H, Jansen L, Andres A. Excessive Gestational Weight Gain, independent of BMI, is associated with Child Fat Mass Index at age 2 years in the Glowing Study. J Acad Nutr Diet. 2024 Oct 17. PMID: 39426519.
      View in: PubMed
    2. Fiecke C, Crimmins M, Hameed A, Sims C, Williams DK, Bode L, Martinez A, Andres A, Ferruzzi MG. Dietary modulation of human milk bioactives is associated with maternal FUT2 secretor phenotype: an exploratory analysis of carotenoids and polyphenol metabolites. Front Nutr. 2024; 11:1463969. PMID: 39444568.
      View in: PubMed
    3. McCorkle G, Andres A, Sims CR, Casey PH, Sorensen ST, Durey T, Bellando J. Exploring the relationship between child temperament, maternal psychiatric symptoms, family environment and infant feeding. Matern Child Nutr. 2024 Sep 03; e13728. PMID: 39228139.
      View in: PubMed
    4. Gurung M, Mulakala BK, Schlegel BT, Rajasundaram D, Shankar K, Bode L, Ruebel ML, Sims C, Martinez A, Andres A, Yeruva L. Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome. Clin Nutr ESPEN. 2024 Oct; 63:903-918. PMID: 39209027.
      View in: PubMed
    5. McGehee DL, Saben JL, Sims CR, Turner D, Thakali KM, Diaz EC, Sobik SR, Edwards T, Krukowski RA, Williams DK, B?rsheim E, Andres A. Childhood cardiometabolic risk factors associated with the perinatal environment of the maternal-paternal-child triad. Pediatr Obes. 2024 Aug 25; e13162. PMID: 39183454.
      View in: PubMed
    6. Sparks JR, Redman LM, Drews KL, Sims CR, Krukowski RA, Andres A. Healthful Eating Behaviors among Couples Contribute to Lower Gestational Weight Gain. Nutrients. 2024 Mar 13; 16(6). PMID: 38542733.
      View in: PubMed
    7. Sims CR, Saben JL, Martinez A, Sobik SR, Crimmins MR, Bulmanski JE, Turner D, Furst A, Jansen LT, Bode L, Andres A. A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition - a feasibility study. Front Nutr. 2024; 11:1303822. PMID: 38544749.
      View in: PubMed
    8. Crimmins MR, Hand M, Samuel H, Bellando J, Sims CR, Andres A, Sobik S. The Impact of Excessive Weight on Breastfeeding Intention, Initiation, and Duration. Breastfeed Med. 2023 09; 18(9):688-695. PMID: 37729033.
      View in: PubMed
    9. Chen JR, Samuel HA, Shlisky J, Sims CR, Lazarenko OP, Williams DK, Andres A, Badger TM. A longitudinal observational study of skeletal development between ages 3 mo and 6 y in children fed human milk, milk formula, or soy formula. Am J Clin Nutr. 2023 06; 117(6):1211-1218. PMID: 37028556.
      View in: PubMed
    10. Sobik S, Sims CR, Crimmins M, Bimali M, Williams DK, Andres A. Associations Between Maternal Physical Activity, Maternal Lipid Levels, and Infant Anthropometric Outcomes at Two Weeks of Age. Matern Child Health J. 2023 Jan; 27(1):168-177. PMID: 36352287.
      View in: PubMed
    11. Diaz EC, Williams DK, Cotter M, Sims CR, Wolfe RR, Andres A, B?rsheim E. Breastfeeding duration modifies the association between maternal weight status and offspring dietary palmitate oxidation. Am J Clin Nutr. 2022 08 04; 116(2):404-414. PMID: 35404455.
      View in: PubMed
    12. Gilley SP, Ruebel ML, Sims C, Zhong Y, Turner D, Lan RS, Pack LM, Piccolo BD, Chintapalli SV, Abraham A, Bode L, Andres A, Shankar K. Associations between maternal obesity and offspring gut microbiome in the first year of life. Pediatr Obes. 2022 09; 17(9):e12921. PMID: 35478493.
      View in: PubMed
    13. Saben JL, Sims CR, Pack L, Lan R, B?rsheim E, Andres A. Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index. Pediatr Obes. 2022 05; 17(5):e12876. PMID: 34913264.
      View in: PubMed
    14. Ruebel ML, Gilley SP, Sims CR, Zhong Y, Turner D, Chintapalli SV, Piccolo BD, Andres A, Shankar K. Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy. Nutrients. 2021 Sep 21; 13(9). PMID: 34579172.
      View in: PubMed
    15. Fawcett K, Martinez A, Crimmins M, Sims C, B?rsheim E, Andres A. Effect of a dietary and exercise intervention in women with overweight and obesity undergoing fertility treatments: protocol for a randomized controlled trial. BMC Nutr. 2021 Aug 17; 7(1):51. PMID: 34399856.
      View in: PubMed
    16. Saben JL, Sims CR, Abraham A, Bode L, Andres A. Human Milk Oligosaccharide Concentrations and Infant Intakes Are Associated with Maternal Overweight and Obesity and Predict Infant Growth. Nutrients. 2021 Jan 29; 13(2). PMID: 33572881.
      View in: PubMed
    17. Rosa F, Mercer KE, Lin H, Sims CR, Pack LM, Goode G, Badger T, Andres A, Yeruva L. Early Infant Formula Feeding Impacts Urinary Metabolite Profile at 3 Months of Age. Nutrients. 2020 Nov 20; 12(11). PMID: 33233521.
      View in: PubMed
    18. Saben JL, Sims CR, Piccolo BD, Andres A. Maternal adiposity alters the human milk metabolome: associations between nonglucose monosaccharides and infant adiposity. Am J Clin Nutr. 2020 11 11; 112(5):1228-1239. PMID: 32844207.
      View in: PubMed
    19. Sobik S, Sims CR, McCorkle G, Bellando J, Sorensen ST, Badger TM, Casey PH, Williams DK, Andres A. Early infant feeding effect on growth and body composition during the first 6 years and neurodevelopment at age 72 months. Pediatr Res. 2021 07; 90(1):140-147. PMID: 32961547.
      View in: PubMed
    20. Sims CR, Lipsmeyer ME, Turner DE, Andres A. Human milk composition differs by maternal BMI in the first 9 months postpartum. Am J Clin Nutr. 2020 09 01; 112(3):548-557. PMID: 32401302.
      View in: PubMed
    21. Saben JL, Abraham A, Bode L, Sims CR, Andres A. Third-Trimester Glucose Homeostasis in Healthy Women Is Differentially Associated with Human Milk Oligosaccharide Composition at 2 Months Postpartum by Secretor Phenotype. Nutrients. 2020 Jul 24; 12(8). PMID: 32722157.
      View in: PubMed
    22. Harris JE, Pinckard KM, Wright KR, Baer LA, Arts PJ, Abay E, Shettigar VK, Lehnig AC, Robertson B, Madaris K, Canova TJ, Sims C, Goodyear LJ, Andres A, Ziolo MT, Bode L, Stanford KI. Exercise-induced 3'-sialyllactose in breast milk is a critical mediator to improve metabolic health and cardiac function in mouse offspring. Nat Metab. 2020 08; 2(8):678-687. PMID: 32694823.
      View in: PubMed
    23. Bellando J, McCorkle G, Spray B, Sims CR, Badger TM, Casey PH, Scott H, Beall SR, Sorensen ST, Andres A. Developmental assessments during the first 5 years of life in infants fed breast milk, cow's milk formula, or soy formula. Food Sci Nutr. 2020 Jul; 8(7):3469-3478. PMID: 32724610.
      View in: PubMed
    24. Heard-Lipsmeyer ME, Diaz EC, Sims CR, Sobik SR, Ruebel ML, Thakali KM, Krukowski RA, Cleves M, B?rsheim E, Shankar K, Andres A. Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life. Obesity (Silver Spring). 2020 03; 28(3):624-630. PMID: 32030918.
      View in: PubMed
    25. Heard-Lipsmeyer ME, Hull H, Sims CR, Cleves MA, Andres A. Evaluating body composition in infancy and childhood: A comparison between 4C, QMR, DXA, and ADP. Pediatr Obes. 2020 06; 15(6):e12617. PMID: 31986239.
      View in: PubMed
    26. Diaz EC, Cleves MA, DiCarlo M, Sobik SR, Ruebel ML, Thakali KM, Sims CR, Dajani NK, Krukowski RA, B?rsheim E, Badger TM, Shankar K, Andres A. Parental adiposity differentially associates with newborn body composition. Pediatr Obes. 2020 04; 15(4):e12596. PMID: 31856430.
      View in: PubMed
    27. Ruebel ML, Cotter M, Sims CR, Moutos DM, Badger TM, Cleves MA, Shankar K, Andres A. Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective. J Clin Endocrinol Metab. 2017 06 01; 102(6):2029-2038. PMID: 28323970.
      View in: PubMed
    28. Sims CR, Singh SP, Mu S, Gokden N, Zakaria D, Nguyen TC, Mayeux PR. Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome. Front Pharmacol. 2017; 8:237. PMID: 28515693.
      View in: PubMed
    29. Sims CR, Nguyen TC, Mayeux PR. Could Biomarkers Direct Therapy for the Septic Patient? J Pharmacol Exp Ther. 2016 May; 357(2):228-39. PMID: 26857961.
      View in: PubMed
    30. Wang Z, Sims CR, Patil NK, Gokden N, Mayeux PR. Pharmacologic targeting of sphingosine-1-phosphate receptor 1 improves the renal microcirculation during sepsis in the mouse. J Pharmacol Exp Ther. 2015 Jan; 352(1):61-6. PMID: 25355645.
      View in: PubMed
    31. Sims CR, MacMillan-Crow LA, Mayeux PR. Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis. Clin Pharmacol Ther. 2014 Dec; 96(6):662-4. PMID: 25148376.
      View in: PubMed
    32. Mercer KE, Sims CR, Yang CS, Wynne RA, Moutos C, Hogue WR, Lumpkin CK, Suva LJ, Chen JR, Badger TM, Ronis MJ. Loss of functional NADPH oxidase 2 protects against alcohol-induced bone resorption in female p47phox-/- mice. Alcohol Clin Exp Res. 2014 Mar; 38(3):672-82. PMID: 24256560.
      View in: PubMed
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