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Diana Escalona-Vargas

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Neurology
AddressS5/01 Shorey
324 UAMS Campus Dr.
Mail Slot # 512-15
Little Rock AR 72205
Phone501-526-7679
ORCID ORCID Icon0000-0002-9487-0765 Additional info
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    Other Positions
    TitleAssistant Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentObstetrics And Gynecology, College of Medicine
    DivisionGeneralist OB & Gyn


    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Scientific Director of Magnetoencephalography Lab, Department of Pediatrics, Neurology, Arkansas Children’s Hospital, Aug. 2019-Present.


    Collapse Research 
    Collapse research overview
    I specialize in biomedical signal processing and advanced neuroimaging, with a focus on developing and applying novel computational approaches to electrophysiological signals recorded from large-scale sensor arrays. My expertise spans noninvasive brain imaging techniques including magnetoencephalography (MEG), electroencephalography (EEG), intracranial and high-density EEG, and fetal MEG (fMEG).

    My training includes research internships at the Dynamic Neuroimaging Laboratory at McGill University and the SARA/Fetal MEG Research Center at UAMS, both internationally recognized for their contributions to neuroimaging and biomedical signal analysis.

    Currently, I serve as Technical Director of the MEG Laboratory at Arkansas Children’s Hospital (ACH), where I lead clinical and translational MEG studies for pediatric epilepsy and brain tumor. I also direct the hospital’s Transcranial Magnetic Stimulation (TMS) program, expanding noninvasive functional mapping techniques to improve surgical planning in pediatric epilepsy.

    I maintain active research collaborations with the UAMS fMEG Laboratory to investigate maternal–fetal physiology to study how clinical drug exposure affects fetal brain development and the use of emerging optically pumped magnetometer (OPM) systems for fetal magnetocardiography (fMCG). In parallel, I collaborate on adult EEG studies using intracranial and high-density EEG to investigate epilepsy and Parkinson’s disease.

    My broader research interests include multimodal neuroimaging of cognitive development and brain function across the lifespan, with a strong emphasis on translational applications. I am particularly focused on optimizing pre-surgical mapping of language and memory networks in children with epilepsy to improve post-surgical outcomes. A parallel research track investigates how environmental and psychosocial factors—such as obesity, stress, emotional regulation, and functional seizures—impact brain function in pediatric populations.

    Collapse research activities and funding
         (Escalona-Vargas, Diana)Nov 1, 2022 - Oct 31, 2023
    Center for Childhood Obesity Prevention
    Neuroimaging of food-related impulse control and stressors in childhood obesity
    Role: Principal Investigator

    R01HL164303     (ESWARAN, HARI)Mar 15, 2022 - Feb 28, 2026
    NIH
    Development of low-cost optically pumped magnetometer system for fetal applications
    Role: Co-Investigator

    R01HD105412     (ESWARAN, HARI)Sep 8, 2021 - Aug 31, 2025
    NIH
    Magnetoencephalography based tracking of fetal neurodevelopment in diabetic pregnancies
    Role: Co-Investigator

    R01EB031589     (ESWARAN, HARI)Jul 15, 2021 - Mar 31, 2025
    NIH
    Development of Analysis Tools to Enhance Magnetomyographic Assessment of Pelvic Floor Muscles
    Role: Co-Investigator

    GR039097     (ESCALONA-VARGAS, DIANA)Feb 1, 2021 - Jan 31, 2023
    UAMS ACHRI Flow Through
    GR039097-Escalona-Vargas-ACHRI-Pediatric Language and Memory Mapping in Refractory Epilsy using Magnetoencepahlography
    Role: Principal Investigator

    GR039097     (Diana Escalona-Vargas)Feb 1, 2021 - Jan 31, 2023
    Arkansas Children's Research Institute
    Pediatric Language and Memory Mapping in Refractory Epilepsy using Magnetoencephalography
    Role: Principal Investigator

    27312     (ESCALONA-VARGAS, DIANA)Jan 15, 2019 - Jan 14, 2022
    Brain & Behavior Research Foundation
    Studying the effect of Buprenorphine on Fetal Brain Development Using Magnetoencephalography - Continuation
    Role: Principal Investigator

    27312     (ESCALONA-VARGAS, DIANA)Jan 15, 2019 - Jan 14, 2021
    Brain & Behavior Research Foundation
    Studying the effect of Buprenorphine on Fetal Brain Development Using Magnetoencephalography
    Role: Principal Investigator

         (ESCALONA-VARGAS, DIANA I)Jan 1, 2019 - Dec 31, 2019
    UAMS Medical Research Endowment (MRE)
    Buprenorphine on fetal brain development
    Role: Principal Investigator

    R21HD091717     (OLIPHANT, SALLIE SHERROD)Aug 1, 2017 - Jul 31, 2021
    NIH
    Magnetomyography of levator muscle complex in pregnancy and postpartum: Adaptation, injury, and recovery patterns
    Role: Co-Investigator

    R21HD091744     (ESWARAN, HARI)Aug 1, 2017 - Jul 31, 2021
    NIH
    Non-invasive prenatal assessment using optically pumped magnetometers
    Role: Co-Investigator

    1R21HD091717-01     Aug 1, 2017 - Jul 31, 2019
    NIH/National Institutes of Health
    Magnetomyography of levator muscle complex in pregnancy and postpartum: Adaptation, injury, and recovery patterns
    Role: Co-Investigator

    1R21HD091744-01A1     Aug 1, 2017 - Jul 31, 2019
    NIH/National Institutes of Health
    Non-invasive prenatal assessment using optically pumped magnetometers
    Role: Co-Investigator

    OIA-1632891     (LARSON-PRIOR, LINDA)Sep 1, 2016 - Aug 31, 2021
    National Science Foundation - Pass Through: Louisiana Tech University
    RII Track-2 FEC- Probing and Understanding the Brain: Micro and Macro Dynamics of Seizure and Memory Networks - Continuation - Continuation - Continuation
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
    List All   |   Timeline
    1. Oliphant S, Mercado L, Siegel ER, Jones C, Moody H, Escalona-Vargas D, Eswaran H. Magnetomyographic assessment of pelvic floor muscles compared to ultrasound during pregnancy. Physiol Rep. 2025 Mar; 13(5):e70266. PMID: 40059440.
      View in: PubMed
    2. Mercado L, Oliphant S, Escalona-Vargas D, Siegel ER, Moody H, Eswaran H. Comparison of non-invasive magnetomyography to Brink score for assessment of pelvic floor muscle strength. Physiol Meas. 2024 Sep 26; 45(9). PMID: 39250931.
      View in: PubMed
    3. Mercado L, Rose S, Escalona-Vargas D, Dajani N, Siegel ER, Preissl H, Eswaran H. Correlating maternal and cord-blood inflammatory markers and BDNF with human fetal brain activity recorded by magnetoencephalography: An exploratory study. Brain Behav Immun Health. 2024 Aug; 39:100804. PMID: 38979093.
      View in: PubMed
    4. Mercado L, Rose S, Escalona-Vargas D, Siegel ER, Whittington JR, Preissl H, Helmich M, Eswaran H. Correlation of fetal heart rate dynamics to inflammatory markers and brain-derived neurotrophic factor during pregnancy. J Perinat Med. 2024 May 27; 52(4):399-405. PMID: 38404246.
      View in: PubMed
    5. Fu Q, Bustamante-Gomez NC, Reyes-Pardo H, Gubrij I, Escalona-Vargas D, Thostenson JD, Palmieri M, Goellner JJ, Nookaew I, Barnes CL, Stambough JB, Ambrogini E, O'Brien CA. Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation. JCI Insight. 2023 09 22; 8(18). PMID: 37581932.
      View in: PubMed
    6. Mehl ST, Simmons PM, Whittington JR, Escalona-Vargas D, Siegel ER, Lowery CL, Crimmins-Pierce LD, Eswaran H. Assessing uterine electrophysiology prior to elective term induction of labor. Curr Res Physiol. 2023; 6:100103. PMID: 37554388.
      View in: PubMed
    7. Mercado L, Escalona-Vargas D, Blossom S, Siegel ER, Whittington JR, Preissl H, Walden K, Eswaran H. The effect of maternal pregestational diabetes on fetal autonomic nervous system. Physiol Rep. 2023 05; 11(9):e15680. PMID: 37144450.
      View in: PubMed
    8. Escalona-Vargas D, Siegel ER, Oliphant S, Eswaran H. Evaluation of Pelvic Floor Muscles in Pregnancy and Postpartum With Non-Invasive Magnetomyography. IEEE J Transl Eng Health Med. 2022; 10:1800106. PMID: 34950538.
      View in: PubMed
    9. Bolin EH, Escalona-Vargas D, Daily JA, Siegel ER, Lowery CL, Coker J, Stowe ZN, Eswaran H. Magnetocardiographic identification of prolonged fetal corrected QT interval in women receiving treatment for opioid use disorder. J Obstet Gynaecol Res. 2019 Oct; 45(10):1989-1996. PMID: 31297963.
      View in: PubMed
    10. Sippel K, Moser J, Schleger F, Escalona-Vargas D, Preissl H, Rosenstiel W, Spuler M. Fully Automated Subtraction of Heart Activity for Fetal Magnetoencephalography Data. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:5685-5689. PMID: 31947143.
      View in: PubMed
    11. Escalona-Vargas D, Oliphant S, Eswaran H. Magnetomyographic Recordings of Pelvic Floor Activity During Pregnancy and Postpartum: A Novel Non-invasive Approach. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:1855-1858. PMID: 31946259.
      View in: PubMed
    12. Escalona-Vargas D, Coker JL, Ray-Griffith S, Siegel ER, Lowery CL, Stowe ZN, Eswaran H. Fetal assessment in buprenorphine-maintained women using fetal magnetoencephalography: a pilot study. Addiction. 2018 10; 113(10):1895-1904. PMID: 29781091.
      View in: PubMed
    13. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 30387530.
      View in: PubMed
    14. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 30441673.
      View in: PubMed
    15. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 32157908.
      View in: PubMed
    16. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 33086201.
      View in: PubMed
    17. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 22255978.
      View in: PubMed
    18. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 27521462.
      View in: PubMed
    19. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 37884730.
      View in: PubMed
    20. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 38622756.
      View in: PubMed
    21. Eswaran H, Escalona-Vargas D, Bolin EH, Wilson JD, Lowery CL. Fetal magnetocardiography using optically pumped magnetometers: a more adaptable and less expensive alternative? Prenat Diagn. 2017 Feb; 37(2):193-196. PMID: 27891637.
      View in: PubMed
    22. Escalona-Vargas DI, Thagard AS, McGrail K, Napolitano PG, Magann EF, Lowery CL, Eswaran H. Observations of fetal brain activity via non-invasive magnetoencephalography following administration of magnesium sulfate for neuroprotection in preterm labor. Prenat Diagn. 2016 Oct; 36(10):982-984. PMID: 27569124.
      View in: PubMed
    23. Escalona-Vargas D, Siegel ER, Murphy P, Lowery CL, Eswaran H. Selection of Reference Channels Based on Mutual Information for Frequency-Dependent Subtraction Method Applied to Fetal Biomagnetic Signals. IEEE Trans Biomed Eng. 2017 05; 64(5):1115-1122. PMID: 27416588.
      View in: PubMed
    24. Escalona-Vargas D, Govindan RB, Furdea A, Murphy P, Lowery CL, Eswaran H. Characterizing the Propagation of Uterine Electrophysiological Signals Recorded with a Multi-Sensor Abdominal Array in Term Pregnancies. PLoS One. 2015; 10(10):e0140894. PMID: 26505624.
      View in: PubMed
    25. Escalona-Vargas DI, Lopez-Arevalo I, Guti?rrez D. Multicompare tests of the performance of different metaheuristics in EEG dipole source localization. ScientificWorldJournal. 2014; 2014:524367. PMID: 24757424.
      View in: PubMed
    26. Escalona-Vargas DI., Lopez-Arevalo I., and Gutierrez D. On the performance of metaheuristic algorithms in the solution of the EEG inverse problem. Third World Congress on Nature and Biologically Inspired Computing (NaBIC). 2011.
    27. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 28391212.
      View in: PubMed
    28. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 28268470.
      View in: PubMed
    29. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 29582244.
      View in: PubMed
    30. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 33018349.
      View in: PubMed
    31. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 30440290.
      View in: PubMed
    32. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 19523710.
      View in: PubMed
    33. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 35907757.
      View in: PubMed
    34. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 38789219.
      View in: PubMed
    35. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 40021708.
      View in: PubMed
    36. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 40237588.
      View in: PubMed
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