Diana Escalona-Vargas
Title | Assistant Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Peds Pediatrics, College of Medicine |
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Division | Peds Neurology |
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Address | S5/01 Shorey 324 UAMS Campus Dr. Mail Slot # 512-15 Little Rock AR 72205
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Phone | 501-526-7679 |
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ORCID
.gif) | 0000-0002-9487-0765  |
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vCard | Download vCard |
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Title | Assistant Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Obstetrics And Gynecology, College of Medicine |
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Division | Generalist OB & Gyn |
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Biography Scientific Director of Magnetoencephalography Lab, Department of Pediatrics, Neurology, Arkansas Children’s Hospital, Aug. 2019-Present.
Research I specialize in biomedical signal processing and advanced neuroimaging, with a focus on developing and applying novel computational approaches to electrophysiological signals recorded from large-scale sensor arrays. My expertise spans noninvasive brain imaging techniques including magnetoencephalography (MEG), electroencephalography (EEG), intracranial and high-density EEG, and fetal MEG (fMEG).
My training includes research internships at the Dynamic Neuroimaging Laboratory at McGill University and the SARA/Fetal MEG Research Center at UAMS, both internationally recognized for their contributions to neuroimaging and biomedical signal analysis.
Currently, I serve as Technical Director of the MEG Laboratory at Arkansas Children’s Hospital (ACH), where I lead clinical and translational MEG studies for pediatric epilepsy and brain tumor. I also direct the hospital’s Transcranial Magnetic Stimulation (TMS) program, expanding noninvasive functional mapping techniques to improve surgical planning in pediatric epilepsy.
I maintain active research collaborations with the UAMS fMEG Laboratory to investigate maternal–fetal physiology to study how clinical drug exposure affects fetal brain development and the use of emerging optically pumped magnetometer (OPM) systems for fetal magnetocardiography (fMCG). In parallel, I collaborate on adult EEG studies using intracranial and high-density EEG to investigate epilepsy and Parkinson’s disease.
My broader research interests include multimodal neuroimaging of cognitive development and brain function across the lifespan, with a strong emphasis on translational applications. I am particularly focused on optimizing pre-surgical mapping of language and memory networks in children with epilepsy to improve post-surgical outcomes. A parallel research track investigates how environmental and psychosocial factors—such as obesity, stress, emotional regulation, and functional seizures—impact brain function in pediatric populations.
(Escalona-Vargas, Diana)Nov 1, 2022 - Oct 31, 2023 Center for Childhood Obesity Prevention Neuroimaging of food-related impulse control and stressors in childhood obesity Role: Principal Investigator |
| R01HL164303 (ESWARAN, HARI)Mar 15, 2022 - Feb 28, 2026 NIH Development of low-cost optically pumped magnetometer system for fetal applications Role: Co-Investigator |
| R01HD105412 (ESWARAN, HARI)Sep 8, 2021 - Aug 31, 2025 NIH Magnetoencephalography based tracking of fetal neurodevelopment in diabetic pregnancies Role: Co-Investigator |
| R01EB031589 (ESWARAN, HARI)Jul 15, 2021 - Mar 31, 2025 NIH Development of Analysis Tools to Enhance Magnetomyographic Assessment of Pelvic Floor Muscles Role: Co-Investigator |
| GR039097 (ESCALONA-VARGAS, DIANA)Feb 1, 2021 - Jan 31, 2023 UAMS ACHRI Flow Through GR039097-Escalona-Vargas-ACHRI-Pediatric Language and Memory Mapping in Refractory Epilsy using Magnetoencepahlography Role: Principal Investigator |
| GR039097 (Diana Escalona-Vargas)Feb 1, 2021 - Jan 31, 2023 Arkansas Children's Research Institute Pediatric Language and Memory Mapping in Refractory Epilepsy using Magnetoencephalography Role: Principal Investigator |
| 27312 (ESCALONA-VARGAS, DIANA)Jan 15, 2019 - Jan 14, 2022 Brain & Behavior Research Foundation Studying the effect of Buprenorphine on Fetal Brain Development Using Magnetoencephalography - Continuation Role: Principal Investigator |
| 27312 (ESCALONA-VARGAS, DIANA)Jan 15, 2019 - Jan 14, 2021 Brain & Behavior Research Foundation Studying the effect of Buprenorphine on Fetal Brain Development Using Magnetoencephalography Role: Principal Investigator |
| (ESCALONA-VARGAS, DIANA I)Jan 1, 2019 - Dec 31, 2019 UAMS Medical Research Endowment (MRE) Buprenorphine on fetal brain development Role: Principal Investigator |
| R21HD091717 (OLIPHANT, SALLIE SHERROD)Aug 1, 2017 - Jul 31, 2021 NIH Magnetomyography of levator muscle complex in pregnancy and postpartum: Adaptation, injury, and recovery patterns Role: Co-Investigator |
| R21HD091744 (ESWARAN, HARI)Aug 1, 2017 - Jul 31, 2021 NIH Non-invasive prenatal assessment using optically pumped magnetometers Role: Co-Investigator |
| 1R21HD091717-01 Aug 1, 2017 - Jul 31, 2019 NIH/National Institutes of Health Magnetomyography of levator muscle complex in pregnancy and postpartum: Adaptation, injury, and recovery patterns Role: Co-Investigator |
| 1R21HD091744-01A1 Aug 1, 2017 - Jul 31, 2019 NIH/National Institutes of Health Non-invasive prenatal assessment using optically pumped magnetometers Role: Co-Investigator |
| OIA-1632891 (LARSON-PRIOR, LINDA)Sep 1, 2016 - Aug 31, 2021 National Science Foundation - Pass Through: Louisiana Tech University RII Track-2 FEC- Probing and Understanding the Brain: Micro and Macro Dynamics of Seizure and Memory Networks - Continuation - Continuation - Continuation Role: Co-Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Oliphant S, Mercado L, Siegel ER, Jones C, Moody H, Escalona-Vargas D, Eswaran H. Magnetomyographic assessment of pelvic floor muscles compared to ultrasound during pregnancy. Physiol Rep. 2025 Mar; 13(5):e70266. PMID: 40059440.
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Mercado L, Oliphant S, Escalona-Vargas D, Siegel ER, Moody H, Eswaran H. Comparison of non-invasive magnetomyography to Brink score for assessment of pelvic floor muscle strength. Physiol Meas. 2024 Sep 26; 45(9). PMID: 39250931.
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Mercado L, Rose S, Escalona-Vargas D, Dajani N, Siegel ER, Preissl H, Eswaran H. Correlating maternal and cord-blood inflammatory markers and BDNF with human fetal brain activity recorded by magnetoencephalography: An exploratory study. Brain Behav Immun Health. 2024 Aug; 39:100804. PMID: 38979093.
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Mercado L, Rose S, Escalona-Vargas D, Siegel ER, Whittington JR, Preissl H, Helmich M, Eswaran H. Correlation of fetal heart rate dynamics to inflammatory markers and brain-derived neurotrophic factor during pregnancy. J Perinat Med. 2024 May 27; 52(4):399-405. PMID: 38404246.
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Fu Q, Bustamante-Gomez NC, Reyes-Pardo H, Gubrij I, Escalona-Vargas D, Thostenson JD, Palmieri M, Goellner JJ, Nookaew I, Barnes CL, Stambough JB, Ambrogini E, O'Brien CA. Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation. JCI Insight. 2023 09 22; 8(18). PMID: 37581932.
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Mehl ST, Simmons PM, Whittington JR, Escalona-Vargas D, Siegel ER, Lowery CL, Crimmins-Pierce LD, Eswaran H. Assessing uterine electrophysiology prior to elective term induction of labor. Curr Res Physiol. 2023; 6:100103. PMID: 37554388.
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Mercado L, Escalona-Vargas D, Blossom S, Siegel ER, Whittington JR, Preissl H, Walden K, Eswaran H. The effect of maternal pregestational diabetes on fetal autonomic nervous system. Physiol Rep. 2023 05; 11(9):e15680. PMID: 37144450.
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Escalona-Vargas D, Siegel ER, Oliphant S, Eswaran H. Evaluation of Pelvic Floor Muscles in Pregnancy and Postpartum With Non-Invasive Magnetomyography. IEEE J Transl Eng Health Med. 2022; 10:1800106. PMID: 34950538.
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Bolin EH, Escalona-Vargas D, Daily JA, Siegel ER, Lowery CL, Coker J, Stowe ZN, Eswaran H. Magnetocardiographic identification of prolonged fetal corrected QT interval in women receiving treatment for opioid use disorder. J Obstet Gynaecol Res. 2019 Oct; 45(10):1989-1996. PMID: 31297963.
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Sippel K, Moser J, Schleger F, Escalona-Vargas D, Preissl H, Rosenstiel W, Spuler M. Fully Automated Subtraction of Heart Activity for Fetal Magnetoencephalography Data. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:5685-5689. PMID: 31947143.
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Escalona-Vargas D, Oliphant S, Eswaran H. Magnetomyographic Recordings of Pelvic Floor Activity During Pregnancy and Postpartum: A Novel Non-invasive Approach. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:1855-1858. PMID: 31946259.
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Escalona-Vargas D, Coker JL, Ray-Griffith S, Siegel ER, Lowery CL, Stowe ZN, Eswaran H. Fetal assessment in buprenorphine-maintained women using fetal magnetoencephalography: a pilot study. Addiction. 2018 10; 113(10):1895-1904. PMID: 29781091.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 30387530.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 30441673.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 32157908.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 33086201.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 22255978.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 27521462.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 37884730.
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Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 38622756.
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Eswaran H, Escalona-Vargas D, Bolin EH, Wilson JD, Lowery CL. Fetal magnetocardiography using optically pumped magnetometers: a more adaptable and less expensive alternative? Prenat Diagn. 2017 Feb; 37(2):193-196. PMID: 27891637.
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Escalona-Vargas DI, Thagard AS, McGrail K, Napolitano PG, Magann EF, Lowery CL, Eswaran H. Observations of fetal brain activity via non-invasive magnetoencephalography following administration of magnesium sulfate for neuroprotection in preterm labor. Prenat Diagn. 2016 Oct; 36(10):982-984. PMID: 27569124.
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Escalona-Vargas D, Siegel ER, Murphy P, Lowery CL, Eswaran H. Selection of Reference Channels Based on Mutual Information for Frequency-Dependent Subtraction Method Applied to Fetal Biomagnetic Signals. IEEE Trans Biomed Eng. 2017 05; 64(5):1115-1122. PMID: 27416588.
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Escalona-Vargas D, Govindan RB, Furdea A, Murphy P, Lowery CL, Eswaran H. Characterizing the Propagation of Uterine Electrophysiological Signals Recorded with a Multi-Sensor Abdominal Array in Term Pregnancies. PLoS One. 2015; 10(10):e0140894. PMID: 26505624.
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Escalona-Vargas DI, Lopez-Arevalo I, Guti?rrez D. Multicompare tests of the performance of different metaheuristics in EEG dipole source localization. ScientificWorldJournal. 2014; 2014:524367. PMID: 24757424.
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Escalona-Vargas DI., Lopez-Arevalo I., and Gutierrez D. On the performance of metaheuristic algorithms in the solution of the EEG inverse problem. Third World Congress on Nature and Biologically Inspired Computing (NaBIC). 2011.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 28391212.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 28268470.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 29582244.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 33018349.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 30440290.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 19523710.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 35907757.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 38789219.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 40021708.
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McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 40237588.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2011 | 11 | 2014 | 1 | 2015 | 1 | 2016 | 2 | 2017 | 1 | 2018 | 9 | 2019 | 3 | 2021 | 1 | 2023 | 3 | 2024 | 3 | 2025 | 1 |
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