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This is a "connection" page, showing publications co-authored by Peter Crooks and Narsimha Reddy Penthala.

 
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22.445
 
  1. Penthala NR, Balasubramaniam M, Dachavaram SS, Morris EJ, Bhat-Nakshatri P, Ponder J, Jordan CT, Nakshatri H, Crooks PA. Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKKß ubiquitin-like domain (ULD). Eur J Med Chem. 2021 Nov 15; 224:113675.
    View in: PubMed
    Score: 0.909
  2. Penthala NR, Shoeib A, Dachavaram SS, Cabanlong CV, Yang J, Zhan CG, Prather PL, Crooks PA. 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorg Med Chem Lett. 2020 11 15; 30(22):127501.
    View in: PubMed
    Score: 0.858
  3. Penthala NR, Yadlapalli JK, Parkin S, Crooks PA. Crystal structures of (Z)-5-[2-(benzo[b]thio-phen-2-yl)-1-(3,5-di-meth-oxy-phen-yl)ethen-yl]-1H-tetra-zole and (Z)-5-[2-(benzo[b]thio-phen-3-yl)-1-(3,4,5-tri-meth-oxy-phen-yl)ethen-yl]-1H-tetra-zole. Acta Crystallogr E Crystallogr Commun. 2016 May 01; 72(Pt 5):652-5.
    View in: PubMed
    Score: 0.632
  4. Penthala NR, Ketkar A, Sekhar KR, Freeman ML, Eoff RL, Balusu R, Crooks PA. 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1). Bioorg Med Chem. 2015 Nov 15; 23(22):7226-33.
    View in: PubMed
    Score: 0.615
  5. Penthala NR, Madhukuri L, Thakkar S, Madadi NR, Lamture G, Eoff RL, Crooks PA. Synthesis and anti-cancer screening of novel heterocyclic-(2H)-1,2,3-triazoles as potential anti-cancer agents. Medchemcomm. 2015 Aug 01; 6(8):1535-1543.
    View in: PubMed
    Score: 0.599
  6. Penthala NR, Thakkar S, Crooks PA. Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents. Bioorg Med Chem Lett. 2015 Jul 15; 25(14):2763-7.
    View in: PubMed
    Score: 0.594
  7. Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents. Eur J Med Chem. 2015 Mar 06; 92:212-20.
    View in: PubMed
    Score: 0.579
  8. Penthala NR, Madadi NR, Bommagani S, Parkin S, Crooks PA. Comparison of crystal structures of 4-(benzo[b]thio-phen-2-yl)-5-(3,4,5-tri-meth-oxy-phen-yl)-2H-1,2,3-triazole and 4-(benzo[b]thio-phen-2-yl)-2-methyl-5-(3,4,5-tri-meth-oxy-phen-yl)-2H-1,2,3-triazole. Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 01; 70(Pt 11):392-5.
    View in: PubMed
    Score: 0.572
  9. Penthala NR, Madadi NR, Janganati V, Crooks PA. L-Proline catalyzed one-step synthesis of 4,5-diaryl-2H-1,2,3-triazoles from heteroaryl cyanostilbenes via [3+2] cycloaddition of azide. Tetrahedron Lett. 2014 Oct 01; 55(40):5562-5565.
    View in: PubMed
    Score: 0.569
  10. Penthala NR, Bommagani S, Janganati V, Parkin S, Crooks PA. Crystal structure of (E)-13-{4-[(Z)-2-cyano-2-(3,4,5-tri-meth-oxy-phen-yl)ethen-yl]phen-yl}parthenolide methanol hemisolvate. Acta Crystallogr Sect E Struct Rep Online. 2014 Oct 01; 70(Pt 10):o1092-3.
    View in: PubMed
    Score: 0.567
  11. Penthala NR, Bommagani S, Janganati V, MacNicol KB, Cragle CE, Madadi NR, Hardy LL, MacNicol AM, Crooks PA. Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression. Eur J Med Chem. 2014 Oct 06; 85:517-25.
    View in: PubMed
    Score: 0.563
  12. Penthala NR, Bommagani S, Janganati V, Parkin S, Crooks PA. (E)-13-(2-Bromo-phen-yl)micheliolide. Acta Crystallogr Sect E Struct Rep Online. 2014 Mar 01; 70(Pt 3):o251-2.
    View in: PubMed
    Score: 0.544
  13. Penthala NR, Janganati V, Parkin S, Varughese KI, Crooks PA. (E)-13-(4-Amino-phen-yl)parthenolide. Acta Crystallogr Sect E Struct Rep Online. 2013 Oct 26; 69(Pt 11):o1709-10.
    View in: PubMed
    Score: 0.534
  14. Penthala NR, Sonar VN, Horn J, Leggas M, Yadlapalli JS, Crooks PA. Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents. Medchemcomm. 2013 Jul 01; 4(7):1073-1078.
    View in: PubMed
    Score: 0.522
  15. Penthala NR, Ponugoti PR, Nickell JR, Deaciuc AG, Dwoskin LP, Crooks PA. Pyrrolidine analogs of GZ-793A: synthesis and evaluation as inhibitors of the vesicular monoamine transporter-2 (VMAT2). Bioorg Med Chem Lett. 2013 Jun 01; 23(11):3342-5.
    View in: PubMed
    Score: 0.513
  16. Penthala NR, Crooks PA. rac-5-Bromo-N-benzyl-isatincreatinine ethanol monosolvate. Acta Crystallogr Sect E Struct Rep Online. 2013 Feb 01; 69(Pt 2):o288-9.
    View in: PubMed
    Score: 0.507
  17. Penthala NR, Crooks PA. rac-N-Benzyl-isatincreatinine (unknown solvate). Acta Crystallogr Sect E Struct Rep Online. 2013 Feb 01; 69(Pt 2):o290-1.
    View in: PubMed
    Score: 0.507
  18. Penthala NR, Ponugoti PR, Kasam V, Crooks PA. 5-((1-Aroyl-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-diones as potential anticancer agents with anti-inflammatory properties. Bioorg Med Chem Lett. 2013 Mar 01; 23(5):1442-6.
    View in: PubMed
    Score: 0.503
  19. Penthala NR, Ponugoti PR, Parkin S, Crooks PA. rac-(Z)-Methyl 1-benzyl-3-[(3-hy-droxy-quinuclidin-2-yl-idene)meth-yl]-1H-indole-6-carboxyl-ate. Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 01; 68(Pt 11):o3111.
    View in: PubMed
    Score: 0.497
  20. Penthala NR, Parkin S, Crooks PA. (Z)-3-(1H-Indol-3-yl)-2-(3,4,5-tri-methoxy-phen-yl)acrylonitrile. Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 01; 68(Pt 3):o729.
    View in: PubMed
    Score: 0.475
  21. Penthala NR, Parkin S, Crooks PA. (Z)-3-(1-Benzofuran-2-yl)-2-(3,4,5-tri-meth-oxy-phen-yl)acrylonitrile. Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 01; 68(Pt 3):o731.
    View in: PubMed
    Score: 0.475
  22. Penthala NR, Reddy TR, Parkin S, Crooks PA. (2Z,3E)-2-{[1-(4-Chloro-benz-yl)-1H-indol-3-yl]methyl-idene}quinuclidin-3-one oxime. Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 26; 67(Pt 3):o735.
    View in: PubMed
    Score: 0.444
  23. Penthala NR, Yerramreddy TR, Crooks PA. Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents. Bioorg Med Chem Lett. 2011 Mar 01; 21(5):1411-3.
    View in: PubMed
    Score: 0.440
  24. Penthala NR, Eldridge J, Reddy TR, Parkin S, Crooks PA. (E,E)-1-Methyl-2,6-distyrylpyridinium iodide. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26; 66(Pt 7):o1793.
    View in: PubMed
    Score: 0.424
  25. Penthala NR, Yerramreddy TR, Madadi NR, Crooks PA. Synthesis and in vitro evaluation of N-alkyl-3-hydroxy-3-(2-imino-3-methyl-5-oxoimidazolidin-4-yl)indolin-2-one analogs as potential anticancer agents. Bioorg Med Chem Lett. 2010 Aug 01; 20(15):4468-71.
    View in: PubMed
    Score: 0.422
  26. Penthala NR, Yerramreddy TR, Crooks PA. Microwave assisted synthesis and in vitro cytotoxicities of substituted (Z)-2-amino-5-(1-benzyl-1H-indol-3-yl)methylene-1-methyl-1H-imidazol-4(5H)-ones against human tumor cell lines. Bioorg Med Chem Lett. 2010 Jan 15; 20(2):591-3.
    View in: PubMed
    Score: 0.407
  27. Penthala NR, Reddy TR, Parkin S, Crooks PA. 3-(2-Amino-1-methyl-4-oxo-4,5-dihydro-1H-imidazol-5-yl)-5-fluoro-3-hydr-oxy-1-methyl-indolin-2-one methanol hemisolvate. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 31; 65(Pt 11):o2909-10.
    View in: PubMed
    Score: 0.405
  28. Penthala NR, Reddy TR, Parkin S, Crooks PA. 3-(2-Amino-1-methyl-4-oxo-4,5-dihydro-1H-imidazol-5-yl)-3-hydr-oxy-1-phenyl-indolin-2-one ethanol solvate. Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 12; 65(Pt 10):o2439-40.
    View in: PubMed
    Score: 0.401
  29. Penthala NR, Reddy TR, Parkin S, Crooks PA. rac-2-(2-Amino-4-oxo-4,5-dihydro-1,3-thia-zol-5-yl)-2-hydroxy-indane-1,3-dione. Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 18; 65(Pt 8):o1877.
    View in: PubMed
    Score: 0.397
  30. Penthala NR, Reddy TR, Parkin S, Crooks PA. 3-(2-Amino-1-methyl-4-oxo-4,5-dihydro-1H-imidazol-5-yl)-3-hydroxy-indolin-2-one monohydrate. Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 21; 65(Pt 3):o552.
    View in: PubMed
    Score: 0.386
  31. Penthala NR, Reddy TR, Parkin S, Crooks PA. (Z)-Methyl 4-({3-[(2,5-dioxoimidazolidin-4-yl-idene)meth-yl]-1H-indol-1-yl}meth-yl)benzoate. Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 10; 65(Pt 1):o62-3.
    View in: PubMed
    Score: 0.381
  32. Penthala NR, Reddy TR, Parkin S, Crooks PA. (Z)-4-[3-(2,5-Dioxoimidazolidin-4-ylidenemeth-yl)-1H-indol-1-ylmeth-yl]benzonitrile. Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 18; 64(Pt 11):o2122.
    View in: PubMed
    Score: 0.377
  33. Bowroju SK, Penthala NR, Lakkaniga NR, Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ, Crooks PA. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease. Bioorg Med Chem. 2021 09 01; 45:116311.
    View in: PubMed
    Score: 0.228
  34. Albayati ZAF, Penthala NR, Bommagani S, Post GR, Smeltzer MS, Crooks PA. Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone. Toxicol Rep. 2021; 8:359-364.
    View in: PubMed
    Score: 0.221
  35. Yadlapalli JSK, Albayati ZAF, Breen PJ, Dobretsov M, Penthala NR, Hendrickson HP, Crooks PA. A pharmacokinetic study of morphine-6-O-sulfate in rat plasma and brain. Drug Dev Res. 2021 09; 82(6):802-814.
    View in: PubMed
    Score: 0.220
  36. Bowroju SK, Mainali N, Ayyadevara S, Penthala NR, Krishnamachari S, Kakraba S, Reis RJS, Crooks PA. Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aß Self-Aggregation and Metal Chelation-Induced Aß Aggregation. Molecules. 2020 Aug 08; 25(16).
    View in: PubMed
    Score: 0.214
  37. Bommagani S, Penthala NR, Balasubramaniam M, Kuravi S, Caldas-Lopes E, Guzman ML, Balusu R, Crooks PA. A novel tetrazole analogue of resveratrol is a potent anticancer agent. Bioorg Med Chem Lett. 2019 01 15; 29(2):172-178.
    View in: PubMed
    Score: 0.190
  38. Dachavaram SS, Penthala NR, Calahan JL, Munson EJ, Crooks PA. Highly sulphated cellulose: a versatile, reusable and selective desilylating agent for deprotection of alcoholic TBDMS ethers. Org Biomol Chem. 2018 08 22; 16(33):6057-6062.
    View in: PubMed
    Score: 0.186
  39. Madadi NR, Penthala NR, Ketkar A, Eoff RL, Trujullo-Alonso V, Guzman ML, Crooks PA. Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents. Anticancer Agents Med Chem. 2018; 18(4):556-564.
    View in: PubMed
    Score: 0.178
  40. Bommagani S, Ponder J, Penthala NR, Janganati V, Jordan CT, Borrelli MJ, Crooks PA. Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells. Eur J Med Chem. 2017 Aug 18; 136:393-405.
    View in: PubMed
    Score: 0.171
  41. Penthala NR, Janganati V, Alpe TL, Apana SM, Berridge MS, Crooks PA, Borrelli MJ. N-[11CH3]Dimethylaminoparthenolide (DMAPT) uptake into orthotopic 9LSF glioblastoma tumors in the rat. Bioorg Med Chem Lett. 2016 12 15; 26(24):5883-5886.
    View in: PubMed
    Score: 0.165
  42. Madadi NR, Ketkar A, Penthala NR, Bostian AC, Eoff RL, Crooks PA. Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells. Bioorg Med Chem Lett. 2016 May 01; 26(9):2164-9.
    View in: PubMed
    Score: 0.157
  43. Bommagani S, Penthala NR, Parkin S, Crooks PA. Crystal structure of (E)-13-(pyrimidin-5-yl)parthenolide. Acta Crystallogr E Crystallogr Commun. 2015 Dec 01; 71(Pt 12):1536-8.
    View in: PubMed
    Score: 0.154
  44. Janganati V, Ponder J, Jordan CT, Borrelli MJ, Penthala NR, Crooks PA. Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor Cells. J Med Chem. 2015 Nov 25; 58(22):8896-906.
    View in: PubMed
    Score: 0.154
  45. Wan A, Penthala NR, Fifer EK, Parkin S, Crooks PA. Comparison of the crystal structures of 4,4'-bis-[3-(4-methyl-piperidin-1-yl)prop-1-yn-1-yl]-1,1'-biphenyl and 4,4'-bis-[3-(2,2,6,6-tetra-methyl-piperidin-1-yl)prop-1-yn-1-yl]-1,1'-biphen-yl. Acta Crystallogr E Crystallogr Commun. 2015 Oct 01; 71(Pt 10):1132-5.
    View in: PubMed
    Score: 0.152
  46. Wan A, Penthala NR, Fifer EK, Parkin S, Crooks PA. Comparison crystal structure conformations of two structurally related biphenyl analogues: 4,4'-bis-[3-(pyrrolidin-1-yl)prop-1-yn-1-yl]-1,1'-biphenyl and 4,4'-bis-{3-[(S)-2-methyl-pyrrolidin-1-yl]prop-1-yn-1-yl}-1,1'-biphen-yl. Acta Crystallogr E Crystallogr Commun. 2015 Oct 01; 71(Pt 10):1147-50.
    View in: PubMed
    Score: 0.152
  47. Madadi NR, Penthala NR, Howk K, Ketkar A, Eoff RL, Borrelli MJ, Crooks PA. Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4. Eur J Med Chem. 2015 Oct 20; 103:123-32.
    View in: PubMed
    Score: 0.152
  48. Madadi NR, Zong H, Ketkar A, Zheng C, Penthala NR, Janganati V, Bommagani S, Eoff RL, Guzman ML, Crooks PA. Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin. Medchemcomm. 2015 May 01; 6(3):788-794.
    View in: PubMed
    Score: 0.148
  49. Penthala NR, Crooks PA, Freeman ML, Sekhar KR. Development and validation of a novel assay to identify radiosensitizers that target nucleophosmin 1. Bioorg Med Chem. 2015 Jul 01; 23(13):3681-6.
    View in: PubMed
    Score: 0.148
  50. Madadi NR, Penthala NR, Bommagani S, Parkin S, Crooks PA. Crystal structure of 4,5-bis-(3,4,5-tri-meth-oxy-phen-yl)-2H-1,2,3-triazole methanol monosolvate. Acta Crystallogr Sect E Struct Rep Online. 2014 Oct 01; 70(Pt 10):o1128-9.
    View in: PubMed
    Score: 0.142
  51. Janganati V, Penthala NR, Madadi NR, Chen Z, Crooks PA. Anti-cancer activity of carbamate derivatives of melampomagnolide B. Bioorg Med Chem Lett. 2014 Aug 01; 24(15):3499-502.
    View in: PubMed
    Score: 0.139
  52. Janganati V, Penthala NR, Cragle CE, MacNicol AM, Crooks PA. Heterocyclic aminoparthenolide derivatives modulate G(2)-M cell cycle progression during Xenopus oocyte maturation. Bioorg Med Chem Lett. 2014 Apr 15; 24(8):1963-7.
    View in: PubMed
    Score: 0.137
  53. Janganati V, Penthala NR, Madadi NR, Parkin S, Crooks PA. Monosuccinate ester of melampomagnolide B. Acta Crystallogr Sect E Struct Rep Online. 2014 Mar 01; 70(Pt 3):o372-3.
    View in: PubMed
    Score: 0.137
  54. Madadi NR, Penthala NR, Janganati V, Crooks PA. Synthesis and anti-proliferative activity of aromatic substituted 5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione analogs against human tumor cell lines. Bioorg Med Chem Lett. 2014 Jan 15; 24(2):601-3.
    View in: PubMed
    Score: 0.135
  55. Bommagani S, Penthala NR, Janganati V, Parkin S, Crooks PA. 13-(N,N-Di-methyl-amino)-micheliolide 0.08-hydrate. Acta Crystallogr Sect E Struct Rep Online. 2013 Nov 20; 69(Pt 12):o1789-90.
    View in: PubMed
    Score: 0.134
  56. Janganati V, Penthala NR, Parkin S, Crooks PA. 13-(Imidazol-1-yl)-11,13-di-hydro-melampomagnolide B monohydrate. Acta Crystallogr Sect E Struct Rep Online. 2013 Nov 06; 69(Pt 12):o1734-5.
    View in: PubMed
    Score: 0.134
  57. Ding D, Nickell JR, Deaciuc AG, Penthala NR, Dwoskin LP, Crooks PA. Synthesis and evaluation of novel azetidine analogs as potent inhibitors of vesicular [3H]dopamine uptake. Bioorg Med Chem. 2013 Nov 01; 21(21):6771-7.
    View in: PubMed
    Score: 0.132
  58. Zheng G, Horton DB, Penthala NR, Nickell JR, Culver JP, Deaciuc AG, Dwoskin LP, Crooks PA. Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse. Medchemcomm. 2013 Mar; 4(3):564-568.
    View in: PubMed
    Score: 0.128
  59. Madadi NR, Penthala NR, Brents LK, Ford BM, Prather PL, Crooks PA. Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett. 2013 Apr 01; 23(7):2019-21.
    View in: PubMed
    Score: 0.127
  60. Ponugoti PR, Penthala NR, Dwoskin LP, Parkin S, Crooks PA. cis-1-Benzyl-pyrrolidine-2,5-dicarbonitrile. Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 01; 67(Pt 4):o747.
    View in: PubMed
    Score: 0.111
  61. Ponugoti PR, Penthala NR, Dwoskin LP, Parkin S, Crooks PA. cis-2,5-Bis(2-fluoro-5-meth-oxy-pheneth-yl)pyrrolidinium formate. Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 26; 67(Pt 3):o737.
    View in: PubMed
    Score: 0.111
  62. Madadi NR, Reddy TR, Penthala NR, Parkin S, Crooks PA. (Z)-2-Amino-5-[2,4-dimeth-oxy-6-(4-methoxy-styr-yl)benzyl-idene]-1,3-thia-zol-4(5H)-one methanol solvate. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26; 66(Pt 7):o1792.
    View in: PubMed
    Score: 0.106
  63. Yerramreddy TR, Milewski M, Penthala NR, Stinchcomb AL, Crooks PA. Novel 3-O-pegylated carboxylate and 3-O-pegylated carbamate prodrugs of naltrexone for microneedle-enhanced transdermal delivery. Bioorg Med Chem Lett. 2010 Jun 01; 20(11):3280-3.
    View in: PubMed
    Score: 0.105
  64. Reddy TR, Penthala NR, Parkin S, Crooks PA. (Z)-4-[3-(3-Oxoquinuclidin-2-ylidene-meth-yl)-1H-indol-1-ylmeth-yl]benzo-nitrile. Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 04; 64(Pt 11):o2049.
    View in: PubMed
    Score: 0.094
  65. Reddy TR, Penthala NR, Parkin S, Crooks PA. (Z)-Methyl 4-[3-(3-oxoquinuclidin-2-yl-idenemeth-yl)-1H-indol-1-ylmeth-yl]benzoate. Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 04; 64(Pt 11):o2050.
    View in: PubMed
    Score: 0.094
  66. Darrigues E, Zhao EH, De Loose A, Lee MP, Borrelli MJ, Eoff RL, Galileo DS, Penthala NR, Crooks PA, Rodriguez A. Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion. Int J Mol Sci. 2021 Oct 03; 22(19).
    View in: PubMed
    Score: 0.058
  67. Balasubramaniam M, Mainali N, Bowroju SK, Atluri P, Penthala NR, Ayyadevera S, Crooks PA, Shmookler Reis RJ. Structural modeling of GSK3ß implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs. Sci Rep. 2020 10 27; 10(1):18326.
    View in: PubMed
    Score: 0.054
  68. Yang JF, Williams AH, Penthala NR, Prather PL, Crooks PA, Zhan CG. Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands. ACS Chem Neurosci. 2020 10 21; 11(20):3455-3463.
    View in: PubMed
    Score: 0.054
  69. Wang R, Kumar B, Bhat-Nakshatri P, Prasad MS, Jacobsen MH, Ovalle G, Maguire C, Sandusky G, Trivedi T, Mohammad KS, Guise T, Penthala NR, Crooks PA, Liu J, Zimmers T, Nakshatri H. Aging-associated skeletal muscle defects in HER2/Neu transgenic mammary tumor model. JCSM Rapid Commun. 2021 Jan-Jun; 4(1):24-39.
    View in: PubMed
    Score: 0.053
  70. Moore Ii JP, Dachavaram SS, Bommagani S, Penthala NR, Venkatraman P, Foster EJ, Crooks PA, A Hestekin J. Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II. Molecules. 2020 Apr 17; 25(8).
    View in: PubMed
    Score: 0.052
  71. Kakraba S, Ayyadevara S, Penthala NR, Balasubramaniam M, Ganne A, Liu L, Alla R, Bommagani SB, Barger SW, Griffin WST, Crooks PA, Shmookler Reis RJ. A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease. Front Mol Neurosci. 2019; 12:310.
    View in: PubMed
    Score: 0.051
  72. Balasubramaniam M, Ayyadevara S, Ganne A, Kakraba S, Penthala NR, Du X, Crooks PA, Griffin ST, Shmookler Reis RJ. Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases. iScience. 2019 Oct 25; 20:248-264.
    View in: PubMed
    Score: 0.050
  73. Ketkar A, Maddukuri L, Penthala NR, Reed MR, Zafar MK, Crooks PA, Eoff RL. Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms. ACS Chem Biol. 2019 06 21; 14(6):1337-1351.
    View in: PubMed
    Score: 0.049
  74. Ford BM, Cabanlong CV, Tai S, Franks LN, Penthala NR, Crooks PA, Prather PL, Fantegrossi WE. Reduced Tolerance and Asymmetrical Crosstolerance to Effects of the Indole Quinuclidinone Analog PNR-4-20, a G Protein-Biased Cannabinoid 1 Receptor Agonist in Mice: Comparisons with ?9-Tetrahydrocannabinol and JWH-018. J Pharmacol Exp Ther. 2019 05; 369(2):259-269.
    View in: PubMed
    Score: 0.048
  75. Marecki JC, Aarattuthodiyil S, Byrd AK, Penthala NR, Crooks PA, Raney KD. N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3. Bioorg Med Chem Lett. 2019 02 01; 29(3):430-434.
    View in: PubMed
    Score: 0.048
  76. Yadlapalli JSK, Bommagani SB, Mahelona RD, Wan A, Gannon BM, Penthala NR, Dobretsov M, Crooks PA, Fantegrossi WE. Evaluation of morphine-like effects of the mixed mu/delta agonist morphine-6-O-sulfate in rats: Drug discrimination and physical dependence. Pharmacol Res Perspect. 2018 07; 6(4):e00403.
    View in: PubMed
    Score: 0.046
  77. Zafar MK, Maddukuri L, Ketkar A, Penthala NR, Reed MR, Eddy S, Crooks PA, Eoff RL. A Small-Molecule Inhibitor of Human DNA Polymerase ? Potentiates the Effects of Cisplatin in Tumor Cells. Biochemistry. 2018 02 20; 57(7):1262-1273.
    View in: PubMed
    Score: 0.045
  78. Wang R, Bhat-Nakshatri P, Padua MB, Prasad MS, Anjanappa M, Jacobson M, Finnearty C, Sefcsik V, McElyea K, Redmond R, Sandusky G, Penthala N, Crooks PA, Liu J, Zimmers T, Nakshatri H. Pharmacological Dual Inhibition of Tumor and Tumor-Induced Functional Limitations in a Transgenic Model of Breast Cancer. Mol Cancer Ther. 2017 Dec; 16(12):2747-2758.
    View in: PubMed
    Score: 0.044
  79. Ford BM, Franks LN, Tai S, Fantegrossi WE, Stahl EL, Berquist MD, Cabanlong CV, Wilson CD, Penthala NR, Crooks PA, Prather PL. Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development. Pharmacol Res. 2017 Nov; 125(Pt B):161-177.
    View in: PubMed
    Score: 0.043
  80. Han YS, Penthala NR, Oliveira M, Mesplède T, Xu H, Quan Y, Crooks PA, Wainberg MA. Identification of resveratrol analogs as potent anti-dengue agents using a cell-based assay. J Med Virol. 2017 03; 89(3):397-407.
    View in: PubMed
    Score: 0.041
  81. Jang DS, Penthala NR, Apostolov EO, Wang X, Crooks PA, Basnakian AG. Novel cytoprotective inhibitors for apoptotic endonuclease G. DNA Cell Biol. 2015 Feb; 34(2):92-100.
    View in: PubMed
    Score: 0.036
  82. Jang DS, Penthala NR, Apostolov EO, Wang X, Fahmi T, Crooks PA, Basnakian AG. Novel high-throughput deoxyribonuclease 1 assay. J Biomol Screen. 2015 Feb; 20(2):202-11.
    View in: PubMed
    Score: 0.036
  83. Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML. Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization. Int J Radiat Oncol Biol Phys. 2014 Aug 01; 89(5):1106-1114.
    View in: PubMed
    Score: 0.035
  84. Franks LN, Ford BM, Madadi NR, Penthala NR, Crooks PA, Prather PL. Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs. Eur J Pharmacol. 2014 Aug 15; 737:140-8.
    View in: PubMed
    Score: 0.035
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.