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Henry Wong

TitleDepartment Chairperson
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentDermatology, College of Medicine
Address324 UAMS Campus Dr.
Mail Slot # 576
Little Rock AR 72205
Phone501-686-5111
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    Collapse Overview 
    Collapse overview
    Henry K. Wong, M.D., Ph.D. is Professor and Chairman of the University of Arkansas for Medical Sciences Department of Dermatology. Dr. Wong comes to UAMS from Ohio State University Medical Center in Columbus, Ohio, where he was director of immunodermatology and co-director of a multi-disciplinary cutaneous lymphoma clinic at the James Cancer Hospital and Comprehensive Cancer Center. He was also director of the psoriasis clinic, dermatology clinical trials, and the medical dermatology research fellowship at Ohio State. He is nationally known for his expertise on cutaneous T-cell lymphoma.Dr. Wong received his medical and doctoral degrees in biochemistry at New York University School of Medicine and the Sackler Institute of Graduate Biomedical Sciences in New York, NY. He was an intern at Barnes Hospital and the Washington University School of Medicine in St. Louis. Dr. Wong completed his residency in dermatology at Bellevue Hospital and New York University and was a visiting research fellow in immunology at the Cornell University School of Medicine.Wong has been chair of the Biomarker Committee of the U.S. Cutaneous Lymphoma Consortium since 2010, and became a member of the Clinical Guideline Committee of the American Academy of Dermatology in 2014. Since 2009, Dr. Wong has been recognized as one of the Best Doctors in Dermatology.Dr. Wong previously held faculty, research, and clinical positions at the Walter Reed Army Medical Center in Washington, D.C., as well as the Wayne State University School of Medicine and the Henry Ford Health System in Detroit.


    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Chairman, Department of Dermatology

    Collapse credentials

    Collapse Research Funds 
    Collapse research activities
    RD.06.SPR.118161     (WONG, HENRY)Mar 25, 2020
    Galderma - Pass Through: Syneos Health
    A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Subjects with Moderateto-Severe Atopic Dermatitis (249958)
    Role: Principal Investigator

    M16-046     (WONG, HENRY)Jan 31, 2020
    AbbVie Inc
    A Phase 3b Multicenter, Randomized, Double-Blind, Double-Dummy, Active Controlled Study Comparing the Safety and Efficacy of Upadacitinib to Dupilumab in Adult Subjects with Moderate to Severe Atopic Dermatitis (IRB 239608)
    Role: Principal Investigator

    KPL-716-C202     (WONG, HENRY)Nov 22, 2019 - Jan 15, 2020
    Kiniksa Pharmaceuticals, Ltd.
    KPL-716-C202: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Pilot Study to Investigate the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Diseases Characterized by Chronic Pruritus (IRB 249909)
    Role: Principal Investigator

    KPL-716-C201     (WONG, HENRY)Nov 22, 2019
    Kiniksa Pharmaceuticals, Ltd. - Pass Through: Innovaderm Research, Inc.
    KPL-716-C201: A Phase 2a/b, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of KPL-716 in Reducing Pruritus in Subjects with Prurigo Nodularis (IRB 239539)
    Role: Principal Investigator

    R3500-AD-1798     (WONG, HENRY)Sep 26, 2019
    Regeneron Pharmaceuticals - Pass Through: PAREXEL International LLC
    A Randomized, Double-Blind, Placebo-Controlled, Phase 2A Study to Assess the Efficacy and Safety of REGN3500 Monotherapy, and Combination of REGN3500 Plus Dupilumab in Adult Patients with Moderate-to-Severe Atopic Dermatitis (229183)
    Role: Principal Investigator

    R3500-AD-1805     (WONG, HENRY)Sep 20, 2019
    Regeneron Pharmaceuticals - Pass Through: PAREXEL International LLC
    R3500-AD-1805 A Phase 2B, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study Investigating the Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 229151
    Role: Principal Investigator

    E7777-G000-302     (WONG, HENRY)Dec 27, 2018
    Eisai
    A Clinical Study to Demonstrate Safety and Efficacy of E7777 in Persistent or Recurrent Cutaneous T-Cell Lymphoma (IRB 228431)
    Role: Principal Investigator

    HPN-CTCL-01     (WONG, HENRY)Oct 24, 2017 - Oct 25, 2020
    Soligenix, Inc.
    SGX301- A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy of Topical SGX301 (Synthetic Hypericin) and Fluorescent Bulb-Light Irradiation for the Treatment of Cutaneous T-Cell Lymphoma
    Role: Principal Investigator

    EL-1007-01-01     (WONG, HENRY)Jul 11, 2017 - Jun 22, 2020
    Elorac, Inc.
    Evaluate the safety and efficacy of topical naloxone hydrochloride lotion, 0.5%, for the relief of pruritus in patients with the mycosis fungoides (MF) form of cutaneous t-cell lymphoma (CTCL)
    Role: Principal Investigator

    CAIN457FUS01     (WONG, HENRY)Feb 6, 2017 - Feb 28, 2019
    NOVARTIS Pharmaceuticals Corporation
    CHOICE STUDY
    Role: Principal Investigator

    AIN457A2326     (WONG, HENRY)Jan 17, 2017 - Jul 31, 2019
    NOVARTIS Pharmaceuticals Corporation
    CLARITY
    Role: Principal Investigator

    R21CA164911     (WONG, HENRY KEUNG)Jul 25, 2012 - Jun 30, 2014
    NIH/NCI
    Novel Biomarkers in Cutaneous T Cell Lymphoma
    Role: Principal Investigator

    R21AR052877     (WONG, HENRY KEUNG)Jul 17, 2006 - Jun 30, 2009
    NIH/NIAMS
    Gene expression abnormalities in mycosis fungoides
    Role: Principal Investigator

    K08AR047818     (WONG, HENRY KEUNG)Sep 20, 2002 - Jun 30, 2008
    NIH/NIAMS
    Gene expression in memory CD4+T cells.
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Lau LH, Cliff ERS, Wong V, Wong H, Torkamani N, Eer A, Weickhardt A, Grossmann M. Hypocalcaemia following denosumab in prostate cancer: A clinical review. Clin Endocrinol (Oxf). 2020 Jun; 92(6):495-502. PMID: 32017154.
      View in: PubMed
    2. Guthrie J, King C, Battle L, Field H, Motwani P, Wong H, Kaley J, Shiver M, Gao L. Pyoderma gangrenosum developing after chest tube placement in a patient with chronic lymphocytic leukemia. Cutis. 2019 Nov; 104(5):E23-E26. PMID: 31886797.
      View in: PubMed
    3. Moerman-Herzog AM, Acheampong DA, Brooks AG, Blair SM, Hsu PC, Wong HK. Transcriptome analysis of Sézary syndrome and lymphocytic-variant hypereosinophilic syndrome T cells reveals common and divergent genes. Oncotarget. 2019 Aug 20; 10(49):5052-5069. PMID: 31489115.
      View in: PubMed
    4. Wong HK, Hoermann R, Grossmann M. Reversible male hypogonadotropic hypogonadism due to energy deficit. Clin Endocrinol (Oxf). 2019 07; 91(1):3-9. PMID: 30903626.
      View in: PubMed
    5. Bayraktar M, Kockara S, Halic T, Mete M, Wong HK, Iqbal K. Local edge-enhanced active contour for accurate skin lesion border detection. BMC Bioinformatics. 2019 Mar 14; 20(Suppl 2):91. PMID: 30871471.
      View in: PubMed
    6. Wong HK. Developing BET-ter treatments for cutaneous T-cell lymphoma. Oncotarget. 2019 Feb 12; 10(13):1267-1268. PMID: 30863486.
      View in: PubMed
    7. Matlock SM, Rush JL, Afzal W, Fulton EH, Berney SM, Wong HK. Spontaneous ulcerations of the breast. Clin Exp Dermatol. 2020 Jan; 45(1):107-110. PMID: 30618053.
      View in: PubMed
    8. Pitch MA, Kim KH, Manning T, Smoller BR, Wong HK, Kaley JR. A diagnostically challenging case of CD8+ primary cutaneous gamma/delta T-cell lymphoma. Dermatol Online J. 2017 Nov 15; 23(11). PMID: 29447636.
      View in: PubMed
    9. Kern M, Kim KH, Johnson G, Hawkins SD, Wong HK. Dermatitis herpetiformis presenting as pseudovasculitis. JAAD Case Rep. 2017 Sep; 3(5):444-447. PMID: 28971130.
      View in: PubMed
    10. Mahmoud F, Shields B, Makhoul I, Avaritt N, Wong HK, Hutchins LF, Shalin S, Tackett AJ. Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack. Cancer Biol Ther. 2017 Jul 03; 18(7):451-469. PMID: 28513269.
      View in: PubMed
    11. Naidu P, Churilov L, Kong A, Kanaan R, Wong H, Van Mourik A, Yao A, Cornish E, Hachem M, Hart GK, Owen-Jones E, Robbins R, Lam Q, Samaras K, Zajac JD, Ekinci EI. Using Routine Hemoglobin A1c Testing to Determine the Glycemic Status in Psychiatric Inpatients. Front Endocrinol (Lausanne). 2017; 8:53. PMID: 28396652.
      View in: PubMed
    12. Field H, Gao L, Motwani P, Wong HK. Erratum to: Pruritus Reduction with Systemic Anti-lymphoma Treatments in Patients with Cutaneous T Cell Lymphoma: A Narrative Review. Dermatol Ther (Heidelb). 2016 Dec; 6(4):597. PMID: 27747468.
      View in: PubMed
    13. Kaya S, Bayraktar M, Kockara S, Mete M, Halic T, Field HE, Wong HK. Abrupt skin lesion border cutoff measurement for malignancy detection in dermoscopy images. BMC Bioinformatics. 2016 Oct 06; 17(Suppl 13):367. PMID: 27766942.
      View in: PubMed
    14. Field H, Gao L, Motwani P, Wong HK. Pruritus Reduction with Systemic Anti-lymphoma Treatments in Patients with Cutaneous T Cell Lymphoma: A Narrative Review. Dermatol Ther (Heidelb). 2016 Dec; 6(4):579-595. PMID: 27590615.
      View in: PubMed
    15. Haverkos BM, Gru AA, Geyer SM, Bingman AK, Hemminger JA, Mishra A, Wong HK, Pancholi P, Freud AG, Caligiuri MA, Baiocchi RA, Porcu P. Increased Levels of Plasma Epstein Barr Virus DNA Identify a Poor-Risk Subset of Patients With Advanced Stage Cutaneous T-Cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2016 08; 16 Suppl:S181-S190.e4. PMID: 27521316.
      View in: PubMed
    16. Mishra A, La Perle K, Kwiatkowski S, Sullivan LA, Sams GH, Johns J, Curphey DP, Wen J, McConnell K, Qi J, Wong H, Russo G, Zhang J, Marcucci G, Bradner JE, Porcu P, Caligiuri MA. Mechanism, Consequences, and Therapeutic Targeting of Abnormal IL15 Signaling in Cutaneous T-cell Lymphoma. Cancer Discov. 2016 09; 6(9):986-1005. PMID: 27422033.
      View in: PubMed
    17. Wong HK. STAT Assays with a TWIST: Differentiating Sézary Syndrome from Erythrodermic Inflammatory Dermatitis. J Invest Dermatol. 2016 07; 136(7):1313-1315. PMID: 27342033.
      View in: PubMed
    18. Kaffenberger BH, Zhang E, Duncan JR, Jaglowski S, Klisovic RB, Devine SM, Wong HK, Gru AA. Endothelial chimerism in chronic sclerotic-type chronic graft-versus-host disease (GVHD) and GVHD-associated angiomatosis. Br J Dermatol. 2016 Oct; 175(4):782-4. PMID: 26875995.
      View in: PubMed
    19. Zheng L, Leung ET, Wong HK, Lui G, Lee N, To KF, Choy KW, Chan RC, Ip M. Unraveling methylation changes of host macrophages in Mycobacterium tuberculosis infection. Tuberculosis (Edinb). 2016 05; 98:139-48. PMID: 27156630.
      View in: PubMed
    20. Purnell JC, Williams BA, Shalin SC, Wong HK. Mucocutaneous findings associated with interleukin (IL)-17 inhibition. JAAD Case Rep. 2016 Jan; 2(1):92-4. PMID: 27051840.
      View in: PubMed
    21. Tint AN, Hoermann R, Wong H, Ekinci EI, MacIsaac RJ, Jerums G, Zajac JD, Grossmann M. Association of sex hormone-binding globulin and free testosterone with mortality in men with type 2 diabetes mellitus. Eur J Endocrinol. 2016 Jan; 174(1):59-68. PMID: 26483395.
      View in: PubMed
    22. Scarisbrick JJ, Prince HM, Vermeer MH, Quaglino P, Horwitz S, Porcu P, Stadler R, Wood GS, Beylot-Barry M, Pham-Ledard A, Foss F, Girardi M, Bagot M, Michel L, Battistella M, Guitart J, Kuzel TM, Martinez-Escala ME, Estrach T, Papadavid E, Antoniou C, Rigopoulos D, Nikolaou V, Sugaya M, Miyagaki T, Gniadecki R, Sanches JA, Cury-Martins J, Miyashiro D, Servitje O, Muniesa C, Berti E, Onida F, Corti L, Hodak E, Amitay-Laish I, Ortiz-Romero PL, Rodríguez-Peralto JL, Knobler R, Porkert S, Bauer W, Pimpinelli N, Grandi V, Cowan R, Rook A, Kim E, Pileri A, Patrizi A, Pujol RM, Wong H, Tyler K, Stranzenbach R, Querfeld C, Fava P, Maule M, Willemze R, Evison F, Morris S, Twigger R, Talpur R, Kim J, Ognibene G, Li S, Tavallaee M, Hoppe RT, Duvic M, Whittaker SJ, Kim YH. Cutaneous Lymphoma International Consortium Study of Outcome in Advanced Stages of Mycosis Fungoides and Sézary Syndrome: Effect of Specific Prognostic Markers on Survival and Development of a Prognostic Model. J Clin Oncol. 2015 Nov 10; 33(32):3766-73. PMID: 26438120.
      View in: PubMed
    23. Haverkos B, Tyler K, Gru AA, Winardi FK, Frederickson J, Hastings J, Elkins C, Zhang X, Xu-Welliver M, Wong HK, Porcu P. Primary Cutaneous B-Cell Lymphoma: Management and Patterns of Recurrence at the Multimodality Cutaneous Lymphoma Clinic of The Ohio State University. Oncologist. 2015 Oct; 20(10):1161-6. PMID: 26306900.
      View in: PubMed
    24. Kaffenberger B, Haverkos B, Tyler K, Wong HK, Porcu P, Gru AA. Extranodal Marginal Zone Lymphoma-like Presentations of Angioimmunoblastic T-Cell Lymphoma: A T-Cell Lymphoma Masquerading as a B-Cell Lymphoproliferative Disorder. Am J Dermatopathol. 2015 Aug; 37(8):604-13. PMID: 25839892.
      View in: PubMed
    25. Lee GL, Woods KL, Clark L, Peters S, Wong HK, McGwire BS. Short communication: mucocutaneous leishmaniasis in HIV-related immune reconstitution syndrome. AIDS Res Hum Retroviruses. 2015 Sep; 31(9):889-92. PMID: 26154873.
      View in: PubMed
    26. Chan DV, Flynn J, Ziegler R, Wong HK. HLA-DR1 in familial frontal fibrosing alopecia. J Am Acad Dermatol. 2015 Jul; 73(1):e39. PMID: 26089075.
      View in: PubMed
    27. Kaffenberger BH, Kaffenberger JA, Wong H, Jarjour W, Levin D, Bechtel MA. Magnetic resonance elastography and transient elastography as non-invasive analyses for liver fibrosis: can they obviate the need for liver biopsy in psoriasis patients treated with methotrexate? Int J Dermatol. 2015 Jul; 54(7):752-6. PMID: 26108262.
      View in: PubMed
    28. Tyler KH, Haverkos BM, Hastings J, Hu E, Philips R, Gru AA, Welliver MX, Mishra A, Wong HK, Porcu P. The Role of an Integrated Multidisciplinary Clinic in the Management of Patients with Cutaneous Lymphoma. Front Oncol. 2015; 5:136. PMID: 26137450.
      View in: PubMed
    29. Wong HK, Gibson H, Hake T, Geyer S, Frederickson J, Marcucci G, Caligiuri MA, Porcu P, Mishra A. Promoter-Specific Hypomethylation Is Associated with Overexpression of PLS3, GATA6, and TWIST1 in the Sezary Syndrome. J Invest Dermatol. 2015 Aug; 135(8):2084-2092. PMID: 25806852.
      View in: PubMed
    30. Majithia L, Rong Y, Siddiqui F, Hattie T, Gupta N, Weldon M, Chakravarti A, Wong HK, Porcu P, Xu-Welliver M. Treating cutaneous T-cell lymphoma with highly irregular surfaces with photon irradiation using rice as tissue compensator. Front Oncol. 2015; 5:49. PMID: 25759793.
      View in: PubMed
    31. Chan DV, Kartono F, Ziegler R, Abdulwahab N, DiPaola N, Flynn J, Wong HK. Absence of HLA-DR1 positivity in 2 familial cases of frontal fibrosing alopecia. J Am Acad Dermatol. 2014 Nov; 71(5):e208-10. PMID: 25437995.
      View in: PubMed
    32. Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, Hill GR, Wong HK, MacDonald KK, Maillard I, Koreth J, Elias L, Cutler C, Soiffer RJ, Antin JH, Ritz J, Panoskaltsis-Mortari A, Byrd JC, Blazar BR. Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. J Clin Invest. 2014 Nov; 124(11):4867-76. PMID: 25271622.
      View in: PubMed
    33. Kaffenberger BH, Lee GL, Tyler K, Chan DV, Jarjour W, Ariza ME, Williams MV, Wong HK. Current and potential immune therapies and vaccines in the management of psoriasis. Hum Vaccin Immunother. 2014; 10(4):876-86. PMID: 24492530.
      View in: PubMed
    34. Chan DV, Gibson HM, Aufiero BM, Wilson AJ, Hafner MS, Mi QS, Wong HK. Differential CTLA-4 expression in human CD4+ versus CD8+ T cells is associated with increased NFAT1 and inhibition of CD4+ proliferation. Genes Immun. 2014 Jan; 15(1):25-32. PMID: 24173147.
      View in: PubMed
    35. Wong HK. Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma. Discov Med. 2013 Sep; 16(87):71-8. PMID: 23998443.
      View in: PubMed
    36. Kaffenberger BH, Kartono Winardi F, Frederickson J, Porcu P, Wong HK. Periocular cutaneous anaplastic large cell lymphoma clearance with brentuximab vedotin. J Clin Aesthet Dermatol. 2013 Aug; 6(8):29-31. PMID: 24003348.
      View in: PubMed
    37. de Silva S, Wang F, Hake TS, Porcu P, Wong HK, Wu L. Downregulation of SAMHD1 expression correlates with promoter DNA methylation in Sézary syndrome patients. J Invest Dermatol. 2014 Feb; 134(2):562-565. PMID: 23884314.
      View in: PubMed
    38. Kaffenberger BH, Kaffenberger TM, Wong HK. Immunotargeting in the management of psoriasis. Immunotargets Ther. 2013; 2:51-60. PMID: 27471688.
      View in: PubMed
    39. Madigan LM, Kaffenberger BH, Wong HK. Bullae and psoriasiform hyperkeratosis after treatment with golimumab. J Am Acad Dermatol. 2013 Jun; 68(6):e195-6. PMID: 23680221.
      View in: PubMed
    40. Wong HK, Kaffenberger BH, Zirwas M. A palpable erythematous cord over the trunk in a patient with systemic lupus erythematosus. Interstitial granulomatous dermatitis (IGD). JAMA Dermatol. 2013 May; 149(5):609-14. PMID: 23677093.
      View in: PubMed
    41. de Silva S, Hoy H, Hake TS, Wong HK, Porcu P, Wu L. Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells. J Biol Chem. 2013 Mar 29; 288(13):9284-92. PMID: 23426363.
      View in: PubMed
    42. Sihoe AD, Hiranandani R, Wong H, Yeung ES. Operating on a suspicious lung mass without a preoperative tissue diagnosis: pros and cons. Eur J Cardiothorac Surg. 2013 Aug; 44(2):231-7; discussion 237. PMID: 23299236.
      View in: PubMed
    43. Ariza ME, Williams MV, Wong HK. Targeting IL-17 in psoriasis: from cutaneous immunobiology to clinical application. Clin Immunol. 2013 Feb; 146(2):131-9. PMID: 23314273.
      View in: PubMed
    44. Kaffenberger BH, Wong HK, Jarjour W, Andritsos LA. Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation. J Am Acad Dermatol. 2013 Mar; 68(3):489-92. PMID: 22981608.
      View in: PubMed
    45. Gibson HM, Mishra A, Chan DV, Hake TS, Porcu P, Wong HK. Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome. J Invest Dermatol. 2013 Jan; 133(1):249-57. PMID: 22951729.
      View in: PubMed
    46. Sopkovich JA, Anetakis Poulos G, Wong HK. Acrodermatitis continua of hallopeau successfully treated with adalimumab. J Clin Aesthet Dermatol. 2012 Feb; 5(2):60-2. PMID: 22468174.
      View in: PubMed
    47. Wong HK, Bechtel MA. Blistering insights into the pathogenesis of bullous pemphigoid. Clin Immunol. 2012 Feb; 142(2):101-4. PMID: 22217422.
      View in: PubMed
    48. Wong HK, Mishra A, Hake T, Porcu P. Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome). Br J Haematol. 2011 Oct; 155(2):150-66. PMID: 21883142.
      View in: PubMed
    49. Campbell SM, Peters SB, Zirwas MJ, Wong HK. Immunophenotypic diagnosis of primary cutaneous lymphomas: a review for the practicing dermatologist. J Clin Aesthet Dermatol. 2010 Oct; 3(10):21-5. PMID: 20967191.
      View in: PubMed
    50. Chong BF, Dantzer P, Germeroth T, Hafner M, Wilson AJ, Xiao G, Wong HK. Induced Sézary syndrome PBMCs poorly express immune response genes up-regulated in stimulated memory T cells. J Dermatol Sci. 2010 Oct; 60(1):8-20. PMID: 20801618.
      View in: PubMed
    51. Erter J, Alinari L, Darabi K, Gurcan M, Garzon R, Marcucci G, Bechtel MA, Wong H, Porcu P. New targets of therapy in T-cell lymphomas. Curr Drug Targets. 2010 Apr; 11(4):482-93. PMID: 20196721.
      View in: PubMed
    52. Porcu P, Wong HK. We should have a dream: unlocking the workings of the genome in cutaneous T-cell lymphomas. Clin Lymphoma Myeloma. 2009 Dec; 9(6):409-11. PMID: 19951878.
      View in: PubMed
    53. Tang N, Gibson H, Germeroth T, Porcu P, Lim HW, Wong HK. T-plastin (PLS3) gene expression differentiates Sézary syndrome from mycosis fungoides and inflammatory skin diseases and can serve as a biomarker to monitor disease progression. Br J Dermatol. 2010 Feb 01; 162(2):463-6. PMID: 19995369.
      View in: PubMed
    54. Chong BF, Wong HK. Treatment of psoriasis with etanercept in a patient with a history of primary B-cell lymphoma. Clin Exp Dermatol. 2009 Jul; 34(5):e11-3. PMID: 19040508.
      View in: PubMed
    55. Sze SC, Tong Y, Zhang YB, Zhang ZJ, Lau AS, Wong HK, Tsang KW, Ng TB. A novel mechanism: Erxian Decoction, a Chinese medicine formula, for relieving menopausal syndrome. J Ethnopharmacol. 2009 May 04; 123(1):27-33. PMID: 19429335.
      View in: PubMed
    56. Zhou L, Seo KH, Wong HK, Mi QS. MicroRNAs and immune regulatory T cells. Int Immunopharmacol. 2009 May; 9(5):524-7. PMID: 19539573.
      View in: PubMed
    57. Wong HK. Immunopathogenesis of mycosis fungoides/Sézary syndrome (cutaneous T-cell lymphoma). G Ital Dermatol Venereol. 2008 Dec; 143(6):375-83. PMID: 19169210.
      View in: PubMed
    58. Chong BF, Wilson AJ, Gibson HM, Hafner MS, Luo Y, Hedgcock CJ, Wong HK. Immune function abnormalities in peripheral blood mononuclear cell cytokine expression differentiates stages of cutaneous T-cell lymphoma/mycosis fungoides. Clin Cancer Res. 2008 Feb 01; 14(3):646-53. PMID: 18245523.
      View in: PubMed
    59. Lokitz ML, Wong HK. Bexarotene and narrowband ultraviolet B phototherapy combination treatment for mycosis fungoides. Photodermatol Photoimmunol Photomed. 2007 Dec; 23(6):255-7. PMID: 17986063.
      View in: PubMed
    60. Gibson HM, Hedgcock CJ, Aufiero BM, Wilson AJ, Hafner MS, Tsokos GC, Wong HK. Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter. J Immunol. 2007 Sep 15; 179(6):3831-40. PMID: 17785820.
      View in: PubMed
    61. Chong BF, Wong HK. Immunobiologics in the treatment of psoriasis. Clin Immunol. 2007 May; 123(2):129-38. PMID: 17317321.
      View in: PubMed
    62. Tuchinda C, Lim HW, Strickland FM, Guzmán EA, Wong HK. Comparison of broadband UVB, narrowband UVB, broadband UVA and UVA1 on activation of apoptotic pathways in human peripheral blood mononuclear cells. Photodermatol Photoimmunol Photomed. 2007 Feb; 23(1):2-9. PMID: 17254028.
      View in: PubMed
    63. Yu Q, Chow EM, Wong H, Gu J, Mandelboim O, Gray-Owen SD, Ostrowski MA. CEACAM1 (CD66a) promotes human monocyte survival via a phosphatidylinositol 3-kinase- and AKT-dependent pathway. J Biol Chem. 2006 Dec 22; 281(51):39179-93. PMID: 17071610.
      View in: PubMed
    64. Wong HK, Tsokos GC. Fas (CD95) ligation inhibits activation of NF-kappa B by targeting p65-Rel A in a caspase-dependent manner. Clin Immunol. 2006 Oct; 121(1):47-53. PMID: 16765090.
      View in: PubMed
    65. Kontos AP, Kerr HA, Malick F, Fivenson DP, Lim HW, Wong HK. 308-nm excimer laser for the treatment of lymphomatoid papulosis and stage IA mycosis fungoides. Photodermatol Photoimmunol Photomed. 2006 Jun; 22(3):168-71. PMID: 16719874.
      View in: PubMed
    66. Tuchinda C, Wong HK. Etanercept for chronic progressive cutaneous sarcoidosis. J Drugs Dermatol. 2006 Jun; 5(6):538-40. PMID: 16774106.
      View in: PubMed
    67. Lewis TG, Tuchinda C, Lim HW, Wong HK. Life-threatening pustular and erythrodermic psoriasis responding to infliximab. J Drugs Dermatol. 2006 Jun; 5(6):546-8. PMID: 16774108.
      View in: PubMed
    68. Wong HK, Wilson AJ, Gibson HM, Hafner MS, Hedgcock CJ, Berger CL, Edelson RL, Lim HW. Increased expression of CTLA-4 in malignant T-cells from patients with mycosis fungoides -- cutaneous T cell lymphoma. J Invest Dermatol. 2006 Jan; 126(1):212-9. PMID: 16417239.
      View in: PubMed
    69. Aufiero BM, Talwar H, Young C, Krishnan M, Hatfield JS, Lee HK, Wong HK, Hamzavi I, Murakawa GJ. Narrow-band UVB induces apoptosis in human keratinocytes. J Photochem Photobiol B. 2006 Feb 01; 82(2):132-9. PMID: 16309917.
      View in: PubMed
    70. Stern N, Markel G, Arnon TI, Gruda R, Wong H, Gray-Owen SD, Mandelboim O. Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1. J Immunol. 2005 Jun 01; 174(11):6692-701. PMID: 15905509.
      View in: PubMed
    71. Deeb D, Jiang H, Gao X, Hafner MS, Wong H, Divine G, Chapman RA, Dulchavsky SA, Gautam SC. Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation. Mol Cancer Ther. 2004 Jul; 3(7):803-12. PMID: 15252141.
      View in: PubMed
    72. Wang L, Zhang Z, Zhang R, Hafner MS, Wong HK, Jiao Z, Chopp M. Erythropoietin up-regulates SOCS2 in neuronal progenitor cells derived from SVZ of adult rat. Neuroreport. 2004 Jun 07; 15(8):1225-9. PMID: 15167538.
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    73. Krishnan S, Warke VG, Nambiar MP, Wong HK, Tsokos GC, Farber DL. Generation and biochemical analysis of human effector CD4 T cells: alterations in tyrosine phosphorylation and loss of CD3zeta expression. Blood. 2001 Jun 15; 97(12):3851-9. PMID: 11389026.
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    74. Nambiar MP, Enyedy EJ, Warke VG, Krishnan S, Dennis G, Wong HK, Kammer GM, Tsokos GC. T cell signaling abnormalities in systemic lupus erythematosus are associated with increased mutations/polymorphisms and splice variants of T cell receptor zeta chain messenger RNA. Arthritis Rheum. 2001 Jun; 44(6):1336-50. PMID: 11407693.
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    75. Warke VG, Krishnan S, Nambiar MP, Farber DL, Tsokos GC, Wong HK. Identification of differentially expressed genes in human memory (CD45RO+) CD4+ T lymphocytes. Immunol Invest. 2001 May; 30(2):87-101. PMID: 11465674.
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    76. Tsokos GC, Wong HK, Enyedy EJ, Nambiar MP. Immune cell signaling in lupus. Curr Opin Rheumatol. 2000 Sep; 12(5):355-63. PMID: 10990169.
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    77. Wong HK, Kammer GM, Dennis G, Tsokos GC. Abnormal NF-kappa B activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression. J Immunol. 1999 Aug 01; 163(3):1682-9. PMID: 10415075.
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    78. Wong HK, Ziff EB. The human papillomavirus type 16 E7 protein complements adenovirus type 5 E1A amino-terminus-dependent transactivation of adenovirus type 5 early genes and increases ATF and Oct-1 DNA binding activity. J Virol. 1996 Jan; 70(1):332-40. PMID: 8523545.
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    79. Wong HK, Ziff EB. Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters. J Virol. 1994 Aug; 68(8):4910-20. PMID: 8035489.
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